Ambrosin (BioDeep_00000007275)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
Azuleno[4,5-b]furan-2,9-dione,3,3a,4,5,6,6a,9a,9b-octahydro-6,9a-dimethyl-3-methylene-, (3aS,6S,6aR,9aR,9bR)-
化学式: C15H18O3 (246.1256)
中文名称: 豚草素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=C1C(=O)OC2C1CCC(C)C1C=CC(=O)C12C
InChI: InChI=1S/C15H18O3/c1-8-4-5-10-9(2)14(17)18-13(10)15(3)11(8)6-7-12(15)16/h6-8,10-11,13H,2,4-5H2,1,3H3/t8-,10-,11-,13+,15-/m0/s1
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:2629
- KEGG: C09292
- PubChem: 92119
- PubChem: 257272
- Metlin: METLIN67578
- ChEMBL: CHEMBL115843
- KNApSAcK: C00003210
- CAS: 64813-79-2
- CAS: 509-93-3
- PMhub: MS000020596
- PubChem: 11483
- 3DMET: B02836
- NIKKAJI: J10.275J
- LOTUS: LTS0051702
- KNApSAcK: 2629
- LOTUS: LTS0273844
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
79 个相关的物种来源信息
- 4211 - Ambrosia: LTS0051702
- 4211 - Ambrosia: LTS0273844
- 4212 - Ambrosia artemisiifolia:
- 4212 - Ambrosia artemisiifolia: 10.1002/JPS.3030420702
- 4212 - Ambrosia artemisiifolia: 10.1002/PRAC.19883300204
- 4212 - Ambrosia artemisiifolia: 10.1016/0731-7085(89)80139-6
- 4212 - Ambrosia artemisiifolia: 10.1016/J.BSE.2012.06.004
- 4212 - Ambrosia artemisiifolia: 10.1016/S0021-9673(01)82080-X
- 4212 - Ambrosia artemisiifolia: 10.1016/S0367-326X(99)00091-X
- 4212 - Ambrosia artemisiifolia: 10.1021/JO01284A074
- 4212 - Ambrosia artemisiifolia: 10.1021/NP50045A044
- 4212 - Ambrosia artemisiifolia: 10.1055/S-2006-962617
- 4212 - Ambrosia artemisiifolia: 10.1135/CCCC19632257
- 4212 - Ambrosia artemisiifolia: LTS0051702
- 4212 - Ambrosia artemisiifolia: LTS0273844
- 2067517 - Ambrosia hispida:
- 2067517 - Ambrosia hispida: 10.1016/S0031-9422(00)98540-6
- 2067517 - Ambrosia hispida: 10.1021/JO01034A526
- 2067517 - Ambrosia hispida: LTS0051702
- 2067517 - Ambrosia hispida: LTS0273844
- 1028380 - Ambrosia maritima:
- 1028380 - Ambrosia maritima: 10.1002/JPS.3030420702
- 1028380 - Ambrosia maritima: 10.1002/PRAC.19883300204
- 1028380 - Ambrosia maritima: 10.1016/0731-7085(89)80139-6
- 1028380 - Ambrosia maritima: 10.1016/J.BSE.2012.06.004
- 1028380 - Ambrosia maritima: 10.1016/S0021-9673(01)82080-X
- 1028380 - Ambrosia maritima: 10.1016/S0367-326X(99)00091-X
- 1028380 - Ambrosia maritima: 10.1021/JO01284A074
- 1028380 - Ambrosia maritima: 10.1021/NP50045A044
- 1028380 - Ambrosia maritima: 10.1055/S-2006-962617
- 1028380 - Ambrosia maritima: 10.1135/CCCC19632257
- 1028380 - Ambrosia maritima: LTS0051702
- 1028380 - Ambrosia maritima: LTS0273844
- 2364176 - Ambrosia monogyra: 10.1016/0031-9422(91)84213-C
- 2364176 - Ambrosia monogyra: LTS0273844
- 2067519 - Ambrosia peruviana: 10.1016/S0031-9422(00)82350-X
- 2067519 - Ambrosia peruviana: LTS0051702
- 2067519 - Ambrosia peruviana: LTS0273844
- 1538339 - Ambrosia polystachya:
- 1538339 - Ambrosia polystachya: 10.1002/JPS.3030420702
- 1538339 - Ambrosia polystachya: 10.1002/PRAC.19883300204
- 1538339 - Ambrosia polystachya: 10.1016/0731-7085(89)80139-6
- 1538339 - Ambrosia polystachya: 10.1016/J.BSE.2012.06.004
- 1538339 - Ambrosia polystachya: 10.1016/S0021-9673(01)82080-X
- 1538339 - Ambrosia polystachya: 10.1016/S0367-326X(99)00091-X
- 1538339 - Ambrosia polystachya: 10.1021/JO01284A074
- 1538339 - Ambrosia polystachya: 10.1021/NP50045A044
- 1538339 - Ambrosia polystachya: 10.1055/S-2006-962617
- 1538339 - Ambrosia polystachya: 10.1135/CCCC19632257
- 1538339 - Ambrosia polystachya: LTS0051702
- 1538339 - Ambrosia polystachya: LTS0273844
- 29715 - Ambrosia psilostachya: 10.1002/JPS.3030420702
- 29715 - Ambrosia psilostachya: 10.1016/S0031-9422(00)82350-X
- 29715 - Ambrosia psilostachya: LTS0051702
- 1873154 - Ambrosia salsola:
- 1873154 - Ambrosia salsola: 10.1016/0031-9422(88)80208-5
- 1873154 - Ambrosia salsola: LTS0051702
- 1873154 - Ambrosia salsola: LTS0273844
- 1532261 - Ambrosia tenuifolia:
- 1532261 - Ambrosia tenuifolia: 10.1021/JO01284A074
- 4210 - Asteraceae:
- 4210 - Asteraceae: LTS0051702
- 4210 - Asteraceae: LTS0273844
- 2759 - Eukaryota: LTS0051702
- 2759 - Eukaryota: LTS0273844
- 3398 - Magnoliopsida: LTS0051702
- 3398 - Magnoliopsida: LTS0273844
- 35934 - Parthenium: LTS0051702
- 35934 - Parthenium: LTS0273844
- 183063 - Parthenium hysterophorus: 10.1016/0031-9422(89)80189-X
- 183063 - Parthenium hysterophorus: 10.1016/S0031-9422(00)89954-9
- 183063 - Parthenium hysterophorus: LTS0051702
- 183063 - Parthenium hysterophorus: LTS0273844
- 35493 - Streptophyta: LTS0051702
- 35493 - Streptophyta: LTS0273844
- 58023 - Tracheophyta: LTS0051702
- 58023 - Tracheophyta: LTS0273844
- 33090 - Viridiplantae: LTS0051702
- 33090 - Viridiplantae: LTS0273844
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mohammed N A Khalil, Mouchira A Choucry, Amira S El Senousy, Azza Hassan, Salma A El-Marasy, Sally A El Awdan, Farghaly A Omar. Ambrosin, a potent NF-κβ inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin.
PloS one.
2019; 14(7):e0219378. doi:
10.1371/journal.pone.0219378. [PMID: 31276550] - Wendy Soria Sotillo, Rodrigo Villagomez, Sandra Smiljanic, Xiaoli Huang, Atena Malakpour, Sebastian Kempengren, Gloria Rodrigo, Giovanna Almanza, Olov Sterner, Stina Oredsson. Anti-cancer stem cell activity of a sesquiterpene lactone isolated from Ambrosia arborescens and of a synthetic derivative.
PloS one.
2017; 12(9):e0184304. doi:
10.1371/journal.pone.0184304. [PMID: 28863191] - Mohamed E M Saeed, Haider Abdelgadir, Yoshikazu Sugimoto, Hassan E Khalid, Thomas Efferth. Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells.
Journal of ethnopharmacology.
2015 Nov; 174(?):644-58. doi:
10.1016/j.jep.2015.07.005. [PMID: 26165828] - John V W Becker, Marina M van der Merwe, Anna C van Brummelen, Pamisha Pillay, Bridget G Crampton, Edwin M Mmutlane, Chris Parkinson, Fanie R van Heerden, Neil R Crouch, Peter J Smith, Dalu T Mancama, Vinesh J Maharaj. In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling.
Malaria journal.
2011 Oct; 10(?):295. doi:
10.1186/1475-2875-10-295. [PMID: 21985233] - L M Abou Basha, M H el Sayad, A F Allam, M M Osman. The effect of Ambrosia maritima (Damsissa) on the viability of Lymnaea cailliaudi; an experimental study.
Journal of the Egyptian Society of Parasitology.
1994 Dec; 24(3):513-7. doi:
". [PMID: 7844416] - F Alard, C Stievenart, P Vanparys, L Thilemans, S Geerts. Toxicity and mutagenicity of the molluscicidal plant Ambrosia maritima L.
Drug and chemical toxicology.
1991; 14(4):353-73. doi:
10.3109/01480549109011639. [PMID: 1811958] - M F El Sawy, J Duncan, T F Marshall, H K Bassiouny, M A Shehata. The molluscicidal properties of Ambrosia maritima L. (compositae). 1. Design for a molluscicide field trial.
Tropenmedizin und Parasitologie.
1983 Mar; 34(1):11-4. doi:
". [PMID: 6845414] - H A Shoeb, M A El-Emam. The molluscicidal properties of natural products from Ambrosia maritima.
Egyptian journal of bilharziasis.
1976; 3(2):157-67. doi:
. [PMID: 23941] - S J Torrance, R M Wiedhopf, J R Cole. Ambrosin, tumor inhibitory agent from Hymenoclea salsola (Asteraceae).
Journal of pharmaceutical sciences.
1975 May; 64(5):887-8. doi:
10.1002/jps.2600640542. [PMID: 1151669]
