Azadirachtin (BioDeep_00000000692)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


1H,7H-Naphtho[1,8-bc:4,4a-c]difuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-, 5,10a-dimethyl ester, (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-

化学式: C35H44O16 (720.2629)
中文名称: 印楝素
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 61.25%

分子结构信息

SMILES: C/C=C(\C)C(=O)O[C@H]1C[C@@H](OC(C)=O)[C@@]2(C(=O)OC)CO[C@H]3[C@@H](O)[C@@](C)([C@]45O[C@@]4(C)[C@H]4C[C@@H]5O[C@@H]5OC=C[C@@]54O)[C@@H]4[C@@](O)(C(=O)OC)OC[C@@]14[C@@H]32
InChI: InChI=1S/C35H44O16/c1-8-15(2)24(38)49-18-12-19(48-16(3)36)32(26(39)43-6)13-46-21-22(32)31(18)14-47-34(42,27(40)44-7)25(31)29(4,23(21)37)35-20-11-17(30(35,5)51-35)33(41)9-10-45-28(33)50-20/h8-10,17-23,25,28,37,41-42H,11-14H2,1-7H3/b15-8+

描述信息

Azadirachtin A is a member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica). It has a role as a hepatoprotective agent. It is an azadirachtin, an organic heterotetracyclic compound, an acetate ester, an epoxide, an enoate ester, a cyclic hemiketal, a tertiary alcohol, a secondary alcohol and a methyl ester.
Azadirachtin is a natural product found in Azadirachta and Azadirachta indica with data available.
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
[Raw Data] CBB03_Azadirachtin_pos_40eV.txt
[Raw Data] CBB03_Azadirachtin_pos_10eV.txt
[Raw Data] CBB03_Azadirachtin_pos_50eV.txt
[Raw Data] CBB03_Azadirachtin_pos_20eV.txt
[Raw Data] CBB03_Azadirachtin_pos_30eV.txt

同义名列表

36 个代谢物同义名

3-Acetyl-1-tigloylazadirachtinin; Azadirachtinin; Azadirachtin; 1H,7H-Naphtho[1,8-bc:4,4a-c]difuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-, 5,10a-dimethyl ester, (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-; 1H,7H-Naphtho(1,8-bc:4,4a-c)difuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-(((2E)-2-methyl-1-oxo-2-butenyl)oxy)-4-((1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro(2,3-b)oxireno(e)oxepin-1a(2H)-yl)-, dimethyl ester, (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-; dimethyl (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-acetoxy-3,5-dihydroxy-4-[(1aR,2S,3aS,6aS,7S,7aS)-6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}octahydro-1H-naphtho[1,8a-c:4,5-bc]difuran-5,10a(8H)-dicarboxylate; dimethyl (1S,4S,5R,6S,7S,8R,11S,12R,14S,15R)-12-acetyloxy-4,7-dihydroxy-6-[(1S,2S,6S,8S,9R,11S)-2-hydroxy-11-methyl-5,7,10-trioxatetracyclo[6.3.1.02,6.09,11]dodec-3-en-9-yl]-6-methyl-14-[(E)-2-methylbut-2-enoyl]oxy-3,9-dioxatetracyclo[6.6.1.01,5.011,15]pentadecane-4,11-dicarboxylate; Dimethyl (1S,4S,5R,6S,7S,8R,11S,12R,14S,15R)-12-acetyloxy-4,7-dihydroxy-6-[(1S,2S,6S,9R,11S)-2-hydroxy-11-methyl-5,7,10-trioxatetracyclo[6.3.1.02,6.09,11]dodec-3-en-9-yl]-6-methyl-14-[(E)-2-methylbut-2-enoyl]oxy-3,9-dioxatetracyclo[6.6.1.01,5.011,15]pentadecane-4,11-dicarboxylate; dimethyl acetoxy-dihydroxy-[hydroxy(methyl)[?]yl]-methyl-[(E)-2-methylbut-2-enoyl]oxy-[?]dicarboxylate; FTNJWQUOZFUQQJ-NDAWSKJSSA-N; AZADIRACHTIN [MI]; UNII-O4U1SAF85H; Azadirachtin-A; azadirachtin A; Safer BioNEEM; azadyrachtin; Nimbicidine; AZADIRACTIN; O4U1SAF85H; Superneem; NeemAzal; bioneem; Nimurin; Ornazin; neemix; Azatin; Gronim; BIOSAL; Ecozin; Suneem; Oikos; Align; dimethyl 12-acetyloxy-4,7-dihydroxy-6-(2-hydroxy-11-methyl-5,7,10-trioxatetracyclo[6.3.1.02,6.09,11]dodec-3-en-9-yl)-6-methyl-14-[(E)-2-methylbut-2-enoyl]oxy-3,9-dioxatetracyclo[6.6.1.01,5.011,15]pentadecane-4,11-dicarboxylate; Azadirachtinin; 3-Acetyl-1-tigloylazadirachtinin; AZADIRACHTINB(P); Azadirachtin A



数据库引用编号

63 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 BCL2, BIRC5, CASP3, CASP9, CAT, CCND1, HPGDS, MMP3, MYL9, NFKB1, TP53
Peripheral membrane protein 2 CYP1B1, GORASP1
Endoplasmic reticulum membrane 3 BCL2, CYP1B1, HSP90B1
Nucleus 10 BCL2, BIRC5, CASP3, CASP9, CCND1, HSP90B1, MMP3, NFKB1, PCNA, TP53
cytosol 13 BCL2, BIRC5, CASP3, CASP9, CAT, CCND1, HPGDS, HSP90B1, LIPE, MMP3, MYL9, NFKB1, TP53
nuclear body 1 PCNA
centrosome 3 CCND1, PCNA, TP53
nucleoplasm 8 ATP2B1, BIRC5, CASP3, CCND1, HPGDS, NFKB1, PCNA, TP53
Cell membrane 3 ATP2B1, LIPE, TNF
Cytoplasmic side 1 GORASP1
Multi-pass membrane protein 1 ATP2B1
Golgi apparatus membrane 1 GORASP1
Synapse 1 ATP2B1
cell cortex 1 MYL9
cell surface 1 TNF
glutamatergic synapse 2 ATP2B1, CASP3
Golgi apparatus 1 GORASP1
Golgi membrane 2 GORASP1, INS
neuronal cell body 2 CASP3, TNF
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 LIPE
plasma membrane 2 ATP2B1, TNF
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ATP2B1, BCL2, CAT, CYP1B1, HSP90B1, LIPE, TP53
basolateral plasma membrane 1 ATP2B1
caveola 1 LIPE
extracellular exosome 4 ATP2B1, CAT, HSP90B1, PCNA
endoplasmic reticulum 3 BCL2, HSP90B1, TP53
extracellular space 3 INS, MMP3, TNF
perinuclear region of cytoplasm 1 HSP90B1
bicellular tight junction 1 CCND1
mitochondrion 7 BCL2, CASP9, CAT, CYP1B1, MMP3, NFKB1, TP53
protein-containing complex 6 BCL2, BIRC5, CASP9, CAT, HSP90B1, TP53
intracellular membrane-bounded organelle 4 ATP2B1, CAT, CYP1B1, HPGDS
Microsome membrane 1 CYP1B1
postsynaptic density 1 CASP3
Secreted 2 INS, MMP3
extracellular region 6 CAT, HSP90B1, INS, MMP3, NFKB1, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 CAT, TP53
transcription regulator complex 2 NFKB1, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Nucleus membrane 2 BCL2, CCND1
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, CCND1
external side of plasma membrane 1 TNF
Z disc 1 MYL9
microtubule cytoskeleton 1 BIRC5
nucleolus 1 TP53
midbody 2 BIRC5, HSP90B1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 2 MYL9, TP53
Cytoplasm, cytoskeleton, spindle 1 BIRC5
focal adhesion 2 CAT, HSP90B1
microtubule 1 BIRC5
spindle 1 BIRC5
cis-Golgi network 1 GORASP1
extracellular matrix 1 MMP3
Peroxisome 1 CAT
myofibril 1 MYL9
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 TP53
PML body 1 TP53
collagen-containing extracellular matrix 1 HSP90B1
lateral plasma membrane 1 ATP2B1
interphase microtubule organizing center 1 BIRC5
chromatin 3 NFKB1, PCNA, TP53
cell projection 1 ATP2B1
phagocytic cup 1 TNF
Chromosome 1 BIRC5
centriole 1 BIRC5
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
nuclear chromosome 1 BIRC5
Cytoplasm, cell cortex 1 MYL9
Basolateral cell membrane 1 ATP2B1
site of double-strand break 1 TP53
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Chromosome, centromere 1 BIRC5
Chromosome, centromere, kinetochore 1 BIRC5
Melanosome 1 HSP90B1
Presynaptic cell membrane 1 ATP2B1
germ cell nucleus 1 TP53
replication fork 2 PCNA, TP53
myelin sheath 1 BCL2
sperm plasma membrane 1 HSP90B1
stress fiber 1 MYL9
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, INS, NFKB1
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 HSP90B1, INS
nuclear matrix 1 TP53
transcription repressor complex 2 CCND1, TP53
male germ cell nucleus 1 PCNA
specific granule lumen 1 NFKB1
kinetochore 1 BIRC5
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
immunological synapse 1 ATP2B1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
apoptosome 1 CASP9
chromosome, centromeric region 1 BIRC5
nuclear lamina 1 PCNA
Sarcoplasmic reticulum lumen 1 HSP90B1
chromosome passenger complex 1 BIRC5
[Isoform 1]: Nucleus 1 TP53
cytoplasmic microtubule 1 BIRC5
spindle microtubule 1 BIRC5
survivin complex 1 BIRC5
death-inducing signaling complex 1 CASP3
cyclin-dependent protein kinase holoenzyme complex 2 CCND1, PCNA
endocytic vesicle lumen 1 HSP90B1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
muscle myosin complex 1 MYL9
endoplasmic reticulum chaperone complex 1 HSP90B1
BAD-BCL-2 complex 1 BCL2
photoreceptor ribbon synapse 1 ATP2B1
cyclin D1-CDK4 complex 1 CCND1
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[Nuclear factor NF-kappa-B p105 subunit]: Cytoplasm 1 NFKB1
[Nuclear factor NF-kappa-B p50 subunit]: Nucleus 1 NFKB1
I-kappaB/NF-kappaB complex 1 NFKB1
NF-kappaB p50/p65 complex 1 NFKB1
cyclin D1-CDK6 complex 1 CCND1
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Siti Ainnsyah Omar, Sharmilla Ashokhan, Nazia Abdul Majid, Saiful Anuar Karsani, Benjamin Yii Chung Lau, Jamilah Syafawati Yaacob. Enhanced azadirachtin production in neem (Azadirachta indica) callus through NaCl elicitation: Insights into differential protein regulation via shotgun proteomics. Pesticide biochemistry and physiology. 2024 Feb; 199(?):105778. doi: 10.1016/j.pestbp.2024.105778. [PMID: 38458685]
  • Celeste E Wheeler, Christine Vandervoort, John C Wise. Trunk injection to control Xylosandrus germanus (Coleoptera: Curculionidae) in topworked apple trees. Journal of economic entomology. 2023 Nov; ?(?):. doi: 10.1093/jee/toad217. [PMID: 38011810]
  • Natalie Constancio, Douglas Higgins, Mary Hausbeck, Zsofia Szendrei. Managing insect and plant pathogen pests with organic and conventional pesticides in onions. Journal of economic entomology. 2023 Nov; ?(?):. doi: 10.1093/jee/toad201. [PMID: 37931224]
  • Siddavaram Nagini, Manikandan Palrasu, Anupam Bishayee. Limonoids from neem (Azadirachta Indica A. Juss.) are potential anticancer drug candidates. Medicinal research reviews. 2023 Aug; ?(?):. doi: 10.1002/med.21988. [PMID: 37589457]
  • Rajendra Acharya, Sushant Raj Sharma, Apurba K Barman, Sang-Mok Kim, Kyeong-Yeoll Lee. Control efficacy of azadirachtin on the fall armyworm, Spodoptera frugiperda (J. E. Smith) by soil drenching. Archives of insect biochemistry and physiology. 2023 Apr; ?(?):e22020. doi: 10.1002/arch.22020. [PMID: 37106481]
  • B J Sampson, N Tabanca, C T Werle, S J Stringer, D E Wedge, R Moraes. Insecticidal Activity of Jatropha Extracts Against the Azalea Lace Bug, Stephanitis pyrioides (Hemiptera: Tingidae). Journal of economic entomology. 2023 02; 116(1):192-201. doi: 10.1093/jee/toac187. [PMID: 36534944]
  • Soumendranath Chatterjee, Souvik Bag, Debraj Biswal, Dipanwita Sarkar Paria, Raktima Bandyopadhyay, Basanta Sarkar, Abhijit Mandal, Tushar Kanti Dangar. Neem-based products as potential eco-friendly mosquito control agents over conventional eco-toxic chemical pesticides-A review. Acta tropica. 2023 Feb; 240(?):106858. doi: 10.1016/j.actatropica.2023.106858. [PMID: 36750152]
  • Sandeep Kumar, Anmol, Upendra Sharma, Sg Eswara Reddy. Insecticidal potential of extracts, fractions, and molecules of Aconitum heterophyllum Wall ex. Royle against aphid Aphis craccivora Koch (Hemiptera: Aphididae). Pest management science. 2022 Dec; ?(?):. doi: 10.1002/ps.7324. [PMID: 36519419]
  • Weihua Zhao, Qun Zheng, Deqiang Qin, Peiru Luo, Cuiyi Ye, Shigang Shen, Dongmei Cheng, Suqing Huang, Lihui Liu, Hanhong Xu, Zhixiang Zhang. Azadirachtin inhibits the development and metabolism of the silk glands of Spodoptera frugiperda and affects spinning behavior. Pest management science. 2022 Dec; 78(12):5293-5301. doi: 10.1002/ps.7151. [PMID: 36053871]
  • Upma Singh, Prasun Roy, Shilpi Sharma. Bacterial inoculants as effective agents in minimizing the non-target impact of azadirachtin pesticide and promoting plant growth of Vigna radiata. Archives of microbiology. 2022 Aug; 204(9):555. doi: 10.1007/s00203-022-03162-8. [PMID: 35962834]
  • Kunyu Zhao, Hao Wu, Ruiquan Hou, Jiyingzi Wu, Yongqing Wang, Suqing Huang, Dongmei Cheng, Hanhong Xu, Zhixiang Zhang. Effects of sublethal azadirachtin on the immune response and midgut microbiome of Apis cerana cerana (Hymenoptera: Apidae). Ecotoxicology and environmental safety. 2022 Jan; 229(?):113089. doi: 10.1016/j.ecoenv.2021.113089. [PMID: 34929506]
  • Meihong Lin, Sifan Yang, Jiguang Huang, Lijuan Zhou. Insecticidal Triterpenes in Meliaceae: Plant Species, Molecules and Activities: Part Ⅰ (Aphanamixis-Chukrasia). International journal of molecular sciences. 2021 Dec; 22(24):. doi: 10.3390/ijms222413262. [PMID: 34948062]
  • Sukun Lin, Shengnan Li, Zhenghui Liu, Li Zhang, Hao Wu, Dongmei Cheng, Zhixiang Zhang. Using Azadirachtin to Transform Spodoptera frugiperda from Pest to Natural Enemy. Toxins. 2021 08; 13(8):. doi: 10.3390/toxins13080541. [PMID: 34437412]
  • Inoussa Sanané, Judith Legrand, Christine Dillmann, Frédéric Marion-Poll. High-Throughput Feeding Bioassay for Lepidoptera Larvae. Journal of chemical ecology. 2021 Jul; 47(7):642-652. doi: 10.1007/s10886-021-01290-x. [PMID: 34331170]
  • Benshui Shu, Haikuo Yu, Yuning Li, Hongxin Zhong, Xiangli Li, Liang Cao, Jintian Lin. Identification of azadirachtin responsive genes in Spodoptera frugiperda larvae based on RNA-seq. Pesticide biochemistry and physiology. 2021 Feb; 172(?):104745. doi: 10.1016/j.pestbp.2020.104745. [PMID: 33518039]
  • Francisco Cen-Pacheco, Araceli Ortiz-Celiseo, Alvaro Peniche-Cardeña, Omar Bravo-Ruiz, Fernando C López-Fentanes, Gerardo Valerio-Alfaro, José J Fernández. Studies on the bioactive flavonoids isolated from Azadirachta indica. Natural product research. 2020 Dec; 34(24):3483-3491. doi: 10.1080/14786419.2019.1579808. [PMID: 30835540]
  • Yueyue Tian, Zejun Chen, Xiaoqin Huang, Lixia Zhang, Zhengqun Zhang. Evaluation of Botanicals for Management of Piercing-Sucking Pests and the Effect on Beneficial Arthropod Populations in Tea Trees Camellia sinensis (L.) O. Kuntze (Theaceae). Journal of insect science (Online). 2020 Nov; 20(6):. doi: 10.1093/jisesa/ieaa101. [PMID: 33211857]
  • Selma Mokrane, Giuseppe Cavallo, Francesco Tortorici, Elena Romero, Alberto Fereres, Khaled Djelouah, Vincenzo Verrastro, Daniele Cornara. Behavioral effects induced by organic insecticides can be exploited for a sustainable control of the Orange Spiny Whitefly Aleurocanthus spiniferus. Scientific reports. 2020 09; 10(1):15746. doi: 10.1038/s41598-020-72972-x. [PMID: 32978466]
  • Yi Zhang, Boyang Liu, Kaixi Huang, Shiying Wang, Rafael Lopes Quirino, Zhi-Xiang Zhang, Chaoqun Zhang. Eco-Friendly Castor Oil-Based Delivery System with Sustained Pesticide Release and Enhanced Retention. ACS applied materials & interfaces. 2020 Aug; 12(33):37607-37618. doi: 10.1021/acsami.0c10620. [PMID: 32814393]
  • Karina D Amaral, Lailla C Gandra, Marco Antonio de Oliveira, Danival J de Souza, Terezinha M C Della Lucia. Effect of azadirachtin on mortality and immune response of leaf-cutting ants. Ecotoxicology (London, England). 2019 Dec; 28(10):1190-1197. doi: 10.1007/s10646-019-02124-z. [PMID: 31696443]
  • N Mukherjee, N Joardar, S P Sinha Babu. Antifilarial activity of azadirachtin fuelled through reactive oxygen species induced apoptosis: a thorough molecular study on Setaria cervi. Journal of helminthology. 2019 Sep; 93(5):519-528. doi: 10.1017/s0022149x18000615. [PMID: 30032733]
  • Hannah Hodgson, Ricardo De La Peña, Michael J Stephenson, Ramesha Thimmappa, Jason L Vincent, Elizabeth S Sattely, Anne Osbourn. Identification of key enzymes responsible for protolimonoid biosynthesis in plants: Opening the door to azadirachtin production. Proceedings of the National Academy of Sciences of the United States of America. 2019 08; 116(34):17096-17104. doi: 10.1073/pnas.1906083116. [PMID: 31371503]
  • G K Challa, D M Firake, G T Behere. Bio-pesticide applications may impair the pollination services and survival of foragers of honey bee, Apis cerana Fabricius in oilseed brassica. Environmental pollution (Barking, Essex : 1987). 2019 Jun; 249(?):598-609. doi: 10.1016/j.envpol.2019.03.048. [PMID: 30933757]
  • Meng Bai, Cai-Juan Zheng, Guo-Lei Huang, Rong-Qing Mei, Bin Wang, You-Ping Luo, Chao Zheng, Zhi-Gang Niu, Guang-Ying Chen. Bioactive Meroterpenoids and Isocoumarins from the Mangrove-Derived Fungus Penicillium sp. TGM112. Journal of natural products. 2019 05; 82(5):1155-1164. doi: 10.1021/acs.jnatprod.8b00866. [PMID: 30990038]
  • Farhan Mahmood Shah, Muhammad Razaq, Qasim Ali, Sarfraz Ali Shad, Muhammad Aslam, Ian C W Hardy. Field evaluation of synthetic and neem-derived alternative insecticides in developing action thresholds against cauliflower pests. Scientific reports. 2019 05; 9(1):7684. doi: 10.1038/s41598-019-44080-y. [PMID: 31118444]
  • Sara R Fernandes, Luisa Barreiros, Rita F Oliveira, Agostinho Cruz, Cristina Prudêncio, Ana Isabel Oliveira, Cláudia Pinho, Nuno Santos, Joaquim Morgado. Chemistry, bioactivities, extraction and analysis of azadirachtin: State-of-the-art. Fitoterapia. 2019 Apr; 134(?):141-150. doi: 10.1016/j.fitote.2019.02.006. [PMID: 30738093]
  • Richa Dubey, Ketaki Patil, Sarath C Dantu, Devika M Sardesai, Parnika Bhatia, Nikita Malik, Jhankar D Acharya, Soham Sarkar, Soumadwip Ghosh, Rajarshi Chakrabarti, Shilpy Sharma, Ashutosh Kumar. Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity. The Biochemical journal. 2019 03; 476(5):889-907. doi: 10.1042/bcj20180820. [PMID: 30814273]
  • Nathan J Herrick, Raymond A Cloyd, Amy L Raudenbush. Systemic Insecticide Applications: Effects on Citrus Mealybug (Hemiptera: Pseudococcidae) Populations Under Greenhouse Conditions. Journal of economic entomology. 2019 02; 112(1):266-276. doi: 10.1093/jee/toy352. [PMID: 30476177]
  • Carmen G Hernández-Valencia, Angélica Román-Guerrero, Ángeles Aguilar-Santamaría, Luis Cira, Keiko Shirai. Cross-Linking Chitosan into Hydroxypropylmethylcellulose for the Preparation of Neem Oil Coating for Postharvest Storage of Pitaya (Stenocereus pruinosus). Molecules (Basel, Switzerland). 2019 Jan; 24(2):. doi: 10.3390/molecules24020219. [PMID: 30634411]
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