Hydrazine (BioDeep_00000005800)
Secondary id: BioDeep_00001867739
human metabolite Endogenous blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: H4N2 (32.0374464)
中文名称: 联胺标准溶液
谱图信息:
最多检出来源 Polyporus(natural_products) 50%
分子结构信息
SMILES: NN
InChI: InChI=1S/H4N2/c1-2/h1-2H2
描述信息
Being bifunctional, with two amines, hydrazine is a key building block for the preparation of many heterocyclic compounds via condensation with a range of difunctional electrophiles. With 2,4-pentanedione, it condenses to give the 3,5-dimethylpyrazole. In the Einhorn-Brunner reaction hydrazines react with imides to give triazoles. Hydrazine is a convenient reductant because the by-products are typically nitrogen gas and water. Thus, it is used as an antioxidant, an oxygen scavenger, and a corrosion inhibitor in water boilers and heating systems. It is also used to reduce metal salts and oxides to the pure metals in electroless nickel plating and plutonium extraction from nuclear reactor waste. Hydrazine is an inorganic chemical compound with the formula N2H4. It is a colourless liquid with an ammonia-like odor and is derived from the same industrial chemistry processes that manufacture ammonia. However, hydrazine has physical properties that are more similar to those of water. The propanone azine is an intermediate in the Atofina-PCUK synthesis. Direct alkylation of hydrazines with alkyl halides in the presence of base affords alkyl-substituted hydrazines, but the reaction is typically inefficient due to poor control on level of substitution (same as in ordinary amines). The reduction of hydrazones to hydrazines present a clean way to produce 1,1-dialkylated hydrazines.
Food contaminant arising from its use as a boiler water additive in production of steam used in food processing
C78281 - Agent Affecting Musculoskeletal System > C1935 - Anticachexia Agent
C471 - Enzyme Inhibitor > C667 - Monoamine Oxidase Inhibitor
D009676 - Noxae > D002273 - Carcinogens
D000970 - Antineoplastic Agents
同义名列表
35 个代谢物同义名
Hydrazine sulfate (1:1) monosodium salt; Hydrazine (hydrazine sulphate); Hydrazine (hydrazine sulfate); Hydrazine phosphate (1:1); Hydrazine phosphate (2:1); Hydrazine Dihydrochloride; Hydrazine sulfate (2:1); Hydrazine (anhydrous); Hydrazine monohydrate; Hydrazine mononitrate; Catalyzed hydrazine; Hydrazine solution; Hydrazine tartrate; Hydrazine sulfate; hydrazine hydrate; Hydrazine nitrate; Nitrogen hydride; Hydrazine base; Oxytreat 35; Scav-ox II; Hydrazines; HYDRAZINE; Hydrazyna; Hydrazin; Amerzine; Segidrin; Levoxine; Diamide; Diazane; Diamine; H2NNH2; Zerox; N2H4; HDZ; Hydrazine
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:15571
- KEGG: C05361
- PubChem: 9321
- HMDB: HMDB0012973
- ChEMBL: CHEMBL1237174
- Wikipedia: Hydrazine
- MetaCyc: 4-HYDROXYMETHYLPHENYLHYDRAZINE
- foodb: FDB013394
- chemspider: 8960
- CAS: 119775-10-9
- CAS: 302-01-2
- PMhub: MS000018675
- PubChem: 7738
- PDB-CCD: HZN
- 3DMET: B00770
- NIKKAJI: J1.516D
- KNApSAcK: 15571
分类词条
相关代谢途径
Reactome(0)
BioCyc(14)
- trans-4-hydroxy-L-proline degradation II
- L-arginine degradation VIII (arginine oxidase pathway)
- methanol and methylamine oxidation to formaldehyde
- superpathway of C1 compounds oxidation to CO2
- superpathway of trimethylamine degradation
- superpathway of coenzyme A biosynthesis I (bacteria)
- methylamine degradation II
- methylamine degradation I
- superpathway of L-lysine degradation
- L-lysine fermentation to acetate and butanoate
- ammonia oxidation I (aerobic)
- ammonia oxidation IV (autotrophic ammonia oxidizers)
- nitrifier denitrification
- ammonia oxidation II (anaerobic)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- ammonia oxidation II (anaerobic):
an oxidized c-type cytochrome + hydrazine ⟶ H+ + N2 + a reduced c-type cytochrome
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yukun Zhang, Chen Xu, Hui Sun, Jindong Ai, Mingguang Ren. A turn-on fluorescent probe for sensing N2H4 in living cells, zebrafishes and plant root with a large turn-on fluorescence signal.
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The Analyst.
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Journal of molecular modeling.
2022 Apr; 28(5):112. doi:
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Analytical and bioanalytical chemistry.
2021 Dec; 413(30):7541-7548. doi:
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Nature chemical biology.
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Analytical and bioanalytical chemistry.
2021 Sep; 413(21):5463-5468. doi:
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2020 Aug; 12(34):38183-38191. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
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Analytical and bioanalytical chemistry.
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