ADP-D-ribose (BioDeep_00000004786)
代谢物信息卡片
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] hydrogen phosphate
化学式: C15H23N5O14P2 (559.0716718)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OC4C(C(C(O4)CO)O)O)O)O)N
InChI: InChI=1S/C15H23N5O14P2/c16-12-7-13(18-3-17-12)20(4-19-7)14-10(23)8(21)5(32-14)1-30-35(26,27)34-36(28,29)31-2-6-9(22)11(24)15(25)33-6/h3-6,8-11,14-15,21-25H,1-2H2,(H,26,27)(H,28,29)(H2,16,17,18)/t5-,6-,8-,9-,10-,11-,14-,15?/m1/s1
描述信息
A nucleotide-sugar having ADP as the nucleotide fragment and D-ribofuranos-5-yl as the sugar component.
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:16960
- KEGG: C01882
- PubChem: 33576
- PubChem: 25200469
- PubChem: 4475880
- Metlin: METLIN65671
- ChEMBL: CHEMBL2360089
- MeSH: Adenosine Diphosphate Ribose
- PMhub: MS000017385
- MetaboLights: MTBLC16960
- ChEBI: CHEBI:16864
- PubChem: 4995
- NIKKAJI: J2.734.735E
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
67 个相关的代谢反应过程信息。
Reactome(66)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Nucleobase catabolism:
H2O + XTP ⟶ PPi + XMP - Purine catabolism:
H2O + XTP ⟶ PPi + XMP - Phosphate bond hydrolysis by NUDT proteins:
ADP-D-ribose + H2O ⟶ AMP + R5P - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
H2O ⟶ ADP-ribose - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
H2O ⟶ ADP-ribose - POLB-Dependent Long Patch Base Excision Repair:
H2O ⟶ ADP-ribose - POLB-Dependent Long Patch Base Excision Repair:
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - DNA Repair:
NTHL1:DHU-dsDNA ⟶ DHU + NTHL1:AP-dsDNA - Base Excision Repair:
NTHL1:DHU-dsDNA ⟶ DHU + NTHL1:AP-dsDNA - Resolution of Abasic Sites (AP sites):
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - POLB-Dependent Long Patch Base Excision Repair:
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - POLB-Dependent Long Patch Base Excision Repair:
H2O + PAR-PARP1,PAR-PARP2 dimers ⟶ ADP-D-ribose + PARP1,PARP2 dimers - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Nucleobase catabolism:
H2O + XTP ⟶ PPi + XMP - Purine catabolism:
H2O + XTP ⟶ PPi + XMP - Phosphate bond hydrolysis by NUDT proteins:
ADP-D-ribose + H2O ⟶ AMP + R5P - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - DNA Repair:
MUTYH:(OGUA:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(OGUA:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Nucleobase catabolism:
H2O + XTP ⟶ PPi + XMP - Purine catabolism:
H2O + XTP ⟶ PPi + XMP - Phosphate bond hydrolysis by NUDT proteins:
ADP-D-ribose + H2O ⟶ AMP + R5P - DNA Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Base Excision Repair:
MUTYH:(8oxoG:Ade)-dsDNA ⟶ Ade + MUTYH:AP-dsDNA - Resolution of Abasic Sites (AP sites):
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - Resolution of AP sites via the multiple-nucleotide patch replacement pathway:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA - POLB-Dependent Long Patch Base Excision Repair:
NAD + PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA ⟶ NAM + PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
Adenosine + Pi ⟶ Adenine + _alpha_-D-Ribose 1-phosphate
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Agata Jacewicz, Swathi Dantuluri, Stewart Shuman. Structural basis for Tpt1-catalyzed 2'-PO4 transfer from RNA and NADP(H) to NAD.
Proceedings of the National Academy of Sciences of the United States of America.
2023 Oct; 120(44):e2312999120. doi:
10.1073/pnas.2312999120. [PMID: 37883434] - Andras Szollosi, János Almássy. Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer.
Scientific reports.
2023 Jul; 13(1):11471. doi:
10.1038/s41598-023-38640-6. [PMID: 37454209] - Nadezhda Spechenkova, Natalya O Kalinina, Sergey K Zavriev, Andrew J Love, Michael Taliansky. ADP-Ribosylation and Antiviral Resistance in Plants.
Viruses.
2023 01; 15(1):. doi:
10.3390/v15010241. [PMID: 36680280] - Sarah Vogt, Karla Feijs, Sebastian Hosch, Raffaella De Masi, Ruth Lintermann, Bernhard Loll, Lennart Wirthmueller. The superior salinity tolerance of bread wheat cultivar Shanrong No. 3 is unlikely to be caused by elevated Ta-sro1 poly-(ADP-ribose) polymerase activity.
The Plant cell.
2022 10; 34(11):4130-4137. doi:
10.1093/plcell/koac261. [PMID: 35980152] - Nilabhra Mitra, Sanghamitra Dey. Understanding the catalytic abilities of class IV sirtuin OsSRT1 and its linkage to the DNA repair system under stress conditions.
Plant science : an international journal of experimental plant biology.
2022 Oct; 323(?):111398. doi:
10.1016/j.plantsci.2022.111398. [PMID: 35917976] - Mizanur Rahman, Martin Irmler, Micol Introna, Johannes Beckers, Lena Palmberg, Gunnar Johanson, Swapna Upadhyay, Koustav Ganguly. Insight into the pulmonary molecular toxicity of heated tobacco products using human bronchial and alveolar mucosa models at air-liquid interface.
Scientific reports.
2022 09; 12(1):16396. doi:
10.1038/s41598-022-20657-y. [PMID: 36180488] - Lavinia M Sherrill, Elva E Joya, AnnMarie Walker, Anuradha Roy, Yousef M Alhammad, Moriama Atobatele, Sarah Wazir, George Abbas, Patrick Keane, Junlin Zhuo, Anthony K L Leung, David K Johnson, Lari Lehtiö, Anthony R Fehr, Dana Ferraris. Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain.
Bioorganic & medicinal chemistry.
2022 08; 67(?):116788. doi:
10.1016/j.bmc.2022.116788. [PMID: 35597097] - Anu Roy, Yousef M Alhammad, Peter McDonald, David K Johnson, Junlin Zhuo, Sarah Wazir, Dana Ferraris, Lari Lehtiö, Anthony K L Leung, Anthony R Fehr. Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening.
Antiviral research.
2022 07; 203(?):105344. doi:
10.1016/j.antiviral.2022.105344. [PMID: 35598780] - Catherine S Nation, Akram A Da'Dara, Patrick J Skelly. NAD-catabolizing ectoenzymes of Schistosoma mansoni.
The Biochemical journal.
2022 06; 479(11):1165-1180. doi:
10.1042/bcj20210784. [PMID: 35593185] - Moona Sakari, Mai T Tran, Jamie Rossjohn, Arto T Pulliainen, Travis Beddoe, Dene R Littler. Crystal structures of pertussis toxin with NAD+ and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
The Journal of biological chemistry.
2022 05; 298(5):101892. doi:
10.1016/j.jbc.2022.101892. [PMID: 35378130] - Alperen Emre Akgün, Yalın Tolga Yaylalı, Mücahit Seçme, Yavuz Dodurga, Hande Şenol. Kynurenine-PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension.
Anatolian journal of cardiology.
2022 05; 26(5):388-393. doi:
10.5152/anatoljcardiol.2021.861. [PMID: 35552175] - Aikaterini C Tsika, Nikolaos K Fourkiotis, Periklis Charalampous, Angelo Gallo, Georgios A Spyroulias. NMR study of macro domains (MDs) from betacoronavirus: backbone resonance assignments of SARS-CoV and MERS-CoV MDs in the free and the ADPr-bound state.
Biomolecular NMR assignments.
2022 04; 16(1):9-16. doi:
10.1007/s12104-021-10052-5. [PMID: 34686999] - Jingjing Fu, Fan Qiu, Cati Raluca Stolniceanu, Fei Yu, Shiming Zang, Yili Xiang, Yue Huang, Milovan Matovic, Cipriana Stefanescu, Qiyun Tang, Feng Wang. Combined use of 177 Lu-DOTATATE peptide receptor radionuclide therapy and fluzoparib for treatment of well-differentiated neuroendocrine tumors: A preclinical study.
Journal of neuroendocrinology.
2022 04; 34(4):e13109. doi:
10.1111/jne.13109. [PMID: 35304807] - Anthony D Rish, Zhangfei Shen, Tian-Min Fu. It takes two to Tango: Two gates orchestrate the opening of human TRPM2.
Cell calcium.
2022 01; 101(?):102523. doi:
10.1016/j.ceca.2021.102523. [PMID: 34973600] - Neel R Nabar, Christopher N Heijjer, Chong-Shan Shi, Il-Young Hwang, Sundar Ganesan, Mikael C I Karlsson, John H Kehrl. LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells.
Autophagy.
2022 01; 18(1):204-222. doi:
10.1080/15548627.2021.1954779. [PMID: 34313548] - Ahmet Hatipoglu, Deepak Menon, Talia Levy, Maria A Frias, David A Foster. Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells.
PloS one.
2022; 17(10):e0276579. doi:
10.1371/journal.pone.0276579. [PMID: 36269753] - Yener Yazğan, Mustafa Nazıroğlu. Involvement of TRPM2 in the Neurobiology of Experimental Migraine: Focus on Oxidative Stress and Apoptosis.
Molecular neurobiology.
2021 Nov; 58(11):5581-5601. doi:
10.1007/s12035-021-02503-w. [PMID: 34370177] - David Hutin, Alexandra S Long, Kim Sugamori, Peng Shao, Sachin Kumar Singh, Marit Rasmussen, Ninni Elise Olafsen, Solveig Pettersen, Giulia Grimaldi, Denis M Grant, Jason Matthews. 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (TiparpH532A) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality.
Toxicological sciences : an official journal of the Society of Toxicology.
2021 08; 183(1):154-169. doi:
10.1093/toxsci/kfab075. [PMID: 34129049] - Chandrabose Selvaraj, Dhurvas Chandrasekaran Dinesh, Umesh Panwar, Evzen Boura, Sanjeev Kumar Singh. High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors Against Mac1 Domain of SARS-CoV-2 Nsp3.
IEEE/ACM transactions on computational biology and bioinformatics.
2021 Jul; 18(4):1262-1270. doi:
10.1109/tcbb.2020.3037136. [PMID: 33306471] - Stephanie C Lüthi, Anna Howald, Kathrin Nowak, Robert Graage, Giody Bartolomei, Christine Neupert, Xaver Sidler, Deena Leslie Pedrioli, Michael O Hottiger. Establishment of a Mass-Spectrometry-Based Method for the Identification of the In Vivo Whole Blood and Plasma ADP-Ribosylomes.
Journal of proteome research.
2021 06; 20(6):3090-3101. doi:
10.1021/acs.jproteome.0c00923. [PMID: 34032442] - Yousef M O Alhammad, Maithri M Kashipathy, Anuradha Roy, Jean-Philippe Gagné, Peter McDonald, Philip Gao, Louis Nonfoux, Kevin P Battaile, David K Johnson, Erik D Holmstrom, Guy G Poirier, Scott Lovell, Anthony R Fehr. The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.
Journal of virology.
2021 01; 95(3):. doi:
10.1128/jvi.01969-20. [PMID: 33158944] - Vinay Ayyappan, Ricky Wat, Calvin Barber, Christina A Vivelo, Kathryn Gauch, Pat Visanpattanasin, Garth Cook, Christos Sazeides, Anthony K L Leung. ADPriboDB 2.0: an updated database of ADP-ribosylated proteins.
Nucleic acids research.
2021 01; 49(D1):D261-D265. doi:
10.1093/nar/gkaa941. [PMID: 33137182] - Collin D Heer, Daniel J Sanderson, Lynden S Voth, Yousef M O Alhammad, Mark S Schmidt, Samuel A J Trammell, Stanley Perlman, Michael S Cohen, Anthony R Fehr, Charles Brenner. Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.
The Journal of biological chemistry.
2020 12; 295(52):17986-17996. doi:
10.1074/jbc.ra120.015138. [PMID: 33051211] - Meng-Hsuan Lin, San-Chi Chang, Yi-Chih Chiu, Bo-Chen Jiang, Tsung-Han Wu, Chun-Hua Hsu. Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain.
ACS infectious diseases.
2020 11; 6(11):2970-2978. doi:
10.1021/acsinfecdis.0c00441. [PMID: 32946224] - Johannes Gregor Matthias Rack, Valentina Zorzini, Zihan Zhu, Marion Schuller, Dragana Ahel, Ivan Ahel. Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential.
Open biology.
2020 11; 10(11):200237. doi:
10.1098/rsob.200237. [PMID: 33202171] - David N Frick, Rajdeep S Virdi, Nemanja Vuksanovic, Narayan Dahal, Nicholas R Silvaggi. Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3.
Biochemistry.
2020 07; 59(28):2608-2615. doi:
10.1021/acs.biochem.0c00309. [PMID: 32578982] - Magdolna Szántó, Peter Bai. The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolism.
Genes & development.
2020 03; 34(5-6):321-340. doi:
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The Plant cell.
2020 03; 32(3):595-611. doi:
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The FEBS journal.
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Cell reports.
2019 06; 27(12):3684-3695.e4. doi:
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Scientific reports.
2019 03; 9(1):4100. doi:
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The International journal of developmental biology.
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American journal of human genetics.
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Nature.
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Biochemical and biophysical research communications.
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Proteins.
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American journal of physiology. Gastrointestinal and liver physiology.
2016 04; 310(7):G497-509. doi:
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Journal of immunology (Baltimore, Md. : 1950).
2015 Sep; 195(5):2057-66. doi:
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American journal of physiology. Renal physiology.
2015 Mar; 308(5):F473-86. doi:
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Proteins.
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Blood.
2014 Sep; 124(11):1715-26. doi:
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Nature reviews. Microbiology.
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The Journal of endocrinology.
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Biogerontology.
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Infection and immunity.
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Journal of cellular and molecular medicine.
2013 Dec; 17(12):1598-607. doi:
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FEBS letters.
2013 Nov; 587(22):3696-702. doi:
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The Biochemical journal.
2013 Nov; 455(3):319-27. doi:
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Free radical biology & medicine.
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Xenobiotica; the fate of foreign compounds in biological systems.
2013 Mar; 43(3):236-45. doi:
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The Plant journal : for cell and molecular biology.
2013 Jan; 73(2):262-75. doi:
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Ultrasonics.
2012 Apr; 52(4):490-6. doi:
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PLoS pathogens.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2011 Oct; 25(10):3529-42. doi:
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Planta.
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The Biochemical journal.
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The Journal of biological chemistry.
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Acta pharmacologica Sinica.
2010 Dec; 31(12):1532-40. doi:
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Experimental biology and medicine (Maywood, N.J.).
2010 Sep; 235(9):1126-33. doi:
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BMC plant biology.
2010 Aug; 10(?):173. doi:
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Toxicology.
2010 May; 271(3):100-6. doi:
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Journal of ethnopharmacology.
2010 Apr; 128(3):654-61. doi:
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Plant physiology.
2010 Apr; 152(4):2000-12. doi:
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Free radical biology & medicine.
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The Journal of membrane biology.
2009 Jul; 230(2):93-9. doi:
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Science signaling.
2009 May; 2(71):ra23. doi:
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Molecular plant.
2009 May; 2(3):442-56. doi:
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The Plant journal : for cell and molecular biology.
2009 Jan; 57(2):289-301. doi:
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Acta biochimica Polonica.
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Journal of immunology (Baltimore, Md. : 1950).
2007 Dec; 179(11):7827-39. doi:
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Neurochemical research.
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Plant physiology.
2007 Sep; 145(1):204-15. doi:
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Molecular biology of the cell.
2007 Aug; 18(8):3015-25. doi:
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Nature.
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Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.
2007 May; 52(6 Suppl):578-84. doi:
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Annals of the New York Academy of Sciences.
2006 Dec; 1090(?):50-8. doi:
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American journal of physiology. Cell physiology.
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Current microbiology.
2006 Oct; 53(4):317-23. doi:
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American journal of physiology. Heart and circulatory physiology.
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American journal of physiology. Renal physiology.
2006 Jul; 291(1):F155-61. doi:
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Journal of pharmacological sciences.
2006 Jun; 101(2):174-8. doi:
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The Journal of biological chemistry.
2006 Feb; 281(5):2489-96. doi:
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Biochemistry.
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The Journal of urology.
2005 Nov; 174(5):2054-9. doi:
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Biochimica et biophysica acta.
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Infection and immunity.
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The Journal of biological chemistry.
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Vaccine.
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2005 Feb; 11(4):1545-50. doi:
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Journal of medicinal chemistry.
2004 Nov; 47(23):5674-82. doi:
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British journal of pharmacology.
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Neuropharmacology.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
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Proceedings of the National Academy of Sciences of the United States of America.
2004 Mar; 101(9):2752-7. doi:
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American journal of obstetrics and gynecology.
2004 Mar; 190(3):680-5. doi:
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Bioscience reports.
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