(E)-Cefixime (BioDeep_00000405778)

Main id: BioDeep_00000002545

 


代谢物信息卡片


Cefixime anhydrous, (E)-

化学式: C16H15N5O7S2 (453.041288)
中文名称: 头孢克肟EP杂质D, 头孢克肟
谱图信息: 最多检出来源 Homo sapiens(urine) 93.33%

分子结构信息

SMILES: C=CC1=C(N2C(C(C2=O)NC(=O)C(=NOCC(=O)O)C3=CSC(=N3)N)SC1)C(=O)O
InChI: InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9+/t10-,14-/m1/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
C254 - Anti-Infective Agent > C258 - Antibiotic > C61101 - Glycopeptide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

3 个代谢物同义名

Cefixime anhydrous, (E)-; (E)-Cefixime; CEFIXIME



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Sepideh Asadi, Bahar Nayeri-Fasaei, Taghi Zahraei-Salehi, Ramak Yahya-Rayat, Nemat Shams, Aram Sharifi. Antibacterial and anti-biofilm properties of carvacrol alone and in combination with cefixime against Escherichia coli. BMC microbiology. 2023 Mar; 23(1):55. doi: 10.1186/s12866-023-02797-x. [PMID: 36864390]
  • Khadijeh Khoshdel, Moones Honarmand, Hassan Hassani. SnO2 and CuO anchored on zeolite as an efficient heterojunction photocatalyst for sunlight-assisted degradation of cefixime. Environmental science and pollution research international. 2023 Mar; 30(13):36883-36903. doi: 10.1007/s11356-022-24635-9. [PMID: 36564689]
  • S Balasurya, Mohammad K Okla, Hamada AbdElgawad, Abdullah A Al-Ghamdi, Mostafa A Abdel-Maksoud, Saud S Al-Amri, Mahmoud M Y Madany, S Sudheer Khan. Self-propelled nanojets an interfacial Schottky junctions modulated oxygen vacancies enriched for enhanced photo-Fenton degradation of organic contaminant: Improving H2O2 generation, Fe3+/Fe2+ cycle and enhancing plant metabolism. Chemosphere. 2023 Feb; 314(?):137516. doi: 10.1016/j.chemosphere.2022.137516. [PMID: 36521743]
  • Xueping Huang, Baihe Wu, Qiuzhao Chen, Yushan Chen, Xinhua Ji, Xiang Zhou, Biao Suo, Zhihui Lin, Xiaoling Zheng. Antibiotic resistance profile of Helicobacter pylori to 14 antibiotics: a multicenter study in Fujian, China. PeerJ. 2023; 11(?):e15611. doi: 10.7717/peerj.15611. [PMID: 37456872]
  • Maryam Ramtin, Fariba Sharifniya, Mohaddeseh Larypoor, Mirsasan Mirpour, Saeid Zarrabi. Evaluation of the Active Ingredient of Campsis radicans Essential Oils and its Antimicrobial Evaluation Against Pathogenic Bacteria. Current microbiology. 2022 Oct; 79(11):338. doi: 10.1007/s00284-022-03042-w. [PMID: 36201048]
  • Phuong Thi Thu Nguyen, Ha Viet Pham, Dung Hoang Van, Linh Van Pham, Hoi Thanh Nguyen, Hung Van Nguyen. Randomized controlled trial of the relative efficacy of high-dose intravenous ceftriaxone and oral cefixime combined with doxycycline for the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae co-infection. BMC infectious diseases. 2022 Jul; 22(1):607. doi: 10.1186/s12879-022-07595-w. [PMID: 35810277]
  • Fatma Ilgaz, Selin Seda Timur, Cemil Can Eylem, Emirhan Nemutlu, Çiğdem Eroğlu Erdem, Hakan Eroğlu, Hülya Gökmen-Özel. Do Thickening Agents Used in Dysphagia Diet Affect Drug Bioavailability?. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2022 Jul; 174(?):106197. doi: 10.1016/j.ejps.2022.106197. [PMID: 35489612]
  • Mahwish Kamran, Mir Azam Khan, Muhammad Shafique, Ghallab Alotaibi, Abdulaziz Al Mouslem, Maqsood Rehman, Muhammad Asghar Khan, Sumaira Gul. Formulation Design, Characterization and In-Vivo Assessment of Cefixime Loaded Binary Solid Lipid Nanoparticles to Enhance Oral Bioavailability. Journal of biomedical nanotechnology. 2022 Apr; 18(4):1215-1226. doi: 10.1166/jbn.2022.3313. [PMID: 35854445]
  • Rozhin Darabi, Mehdi Shabani-Nooshabadi. Development of an amplified nanostructured electrochemical sensor for the detection of cefixime in pharmaceuticals and biological samples. Journal of pharmaceutical and biomedical analysis. 2022 Apr; 212(?):114657. doi: 10.1016/j.jpba.2022.114657. [PMID: 35158186]
  • Di Zhao, Xue-Fang Liu, Yan-Ge Tian, Hao-Ran Dong, Su-Xiang Feng, Jian-Sheng Li. The pharmacokinetic study of Tanreqing and the interaction with cefixime in rat model of pneumonia by validated UPLC-MS/MS. Journal of pharmaceutical and biomedical analysis. 2022 Feb; 209(?):114484. doi: 10.1016/j.jpba.2021.114484. [PMID: 34891004]
  • Bushra Ahmad, Muhammad Rashid Khan, Naseer Ali Shah, Rahmat Ali Khan. In vitro antimicrobial and cytotoxic manifestations of Dicliptera roxburghiana. Pakistan journal of pharmaceutical sciences. 2022 Jan; 35(1):29-34. doi: ". [PMID: 35221269]
  • André Birgy, Fouad Madhi, Camille Jung, Corinne Levy, Aurélie Cointe, Philippe Bidet, Claire Amaris Hobson, Stéphane Bechet, Elsa Sobral, Hoang Vuthien, Agnès Ferroni, Saïd Aberrane, Gaëlle Cuzon, Laetitia Beraud, Vincent Gajdos, Elise Launay, Didier Pinquier, Hervé Haas, Marie Desmarest, Marie-Aliette Dommergues, Robert Cohen, Stéphane Bonacorsi. Clavulanate combinations with mecillinam, cefixime or cefpodoxime against ESBL-producing Enterobacterales frequently associated with blaOXA-1 in a paediatric population with febrile urinary tract infections. The Journal of antimicrobial chemotherapy. 2021 10; 76(11):2839-2846. doi: 10.1093/jac/dkab289. [PMID: 34453533]
  • Chrysovalantis Stafylis, Kori Keith, Shivani Mehta, David Tellalian, Pamela Burian, Carl Millner, Jeffrey D Klausner. Clinical Efficacy of Cefixime for the Treatment of Early Syphilis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 09; 73(5):907-910. doi: 10.1093/cid/ciab187. [PMID: 33640982]
  • Salim Saifullah, Tasmina Kanwal, Shafi Ullah, Muhammad Kawish, Shahida Muhammad Habib, Imdad Ali, Abubakar Munir, Muhammad Imran, Muhammad Raza Shah. Design and development of lipid modified chitosan containing muco-adhesive self-emulsifying drug delivery systems for cefixime oral delivery. Chemistry and physics of lipids. 2021 03; 235(?):105052. doi: 10.1016/j.chemphyslip.2021.105052. [PMID: 33482099]
  • Shivani N Mehta, Chrysovalantis Stafylis, David M Tellalian, Pamela L Burian, Cliff M Okada, Carl E Millner, Christopher M Mejia, Jeffrey D Klausner. Clinical trial protocol to evaluate the efficacy of cefixime in the treatment of early syphilis. Trials. 2020 Dec; 21(1):1009. doi: 10.1186/s13063-020-04885-z. [PMID: 33298143]
  • Alberto Alvarez-Perea, María Luisa Baeza. Anaphylactic shock following the diagnosis of coronavirus disease 2019. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 10; 125(4):477-478. doi: 10.1016/j.anai.2020.07.032. [PMID: 32745608]
  • Azam Mohsenzadeh, Masoud Movahedi, Mohammad Saatchi, Nima Parvaneh, Mansoureh Shariat, Asghar Aghamohammadi, Mohammad Gharagozlou. Serum sickness-like reactions in Iranian children: a registry-based study in a referral center. Allergologia et immunopathologia. 2020 Sep; 48(5):424-429. doi: 10.1016/j.aller.2019.07.012. [PMID: 32653225]
  • Han-Ki Park, Youngwoo Choi, Dong-Hyun Lee, Sujeong Kim, Jong-Myung Lee, Sae Won Choi, Hee-Ra Lee, Mina Rho, Hae-Sim Park. Altered gut microbiota by azithromycin attenuates airway inflammation in allergic asthma. The Journal of allergy and clinical immunology. 2020 05; 145(5):1466-1469.e8. doi: 10.1016/j.jaci.2020.01.044. [PMID: 32035985]
  • Liang-Liang Wang, Narsaiah Battini, Rammohan R Yadav Bheemanaboina, Mohammad Fawad Ansari, Jin-Ping Chen, Yun-Peng Xie, Gui-Xin Cai, Shao-Lin Zhang, Cheng-He Zhou. A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV. European journal of medicinal chemistry. 2019 Oct; 179(?):166-181. doi: 10.1016/j.ejmech.2019.06.046. [PMID: 31254919]
  • Muhammad Waqas Khadam, Muhammad Mudassar Ashraf, Umbreen Naz, Nadeem Irfan Bukhari, Imtiaz Mahmood Tahir, Dawood Asghar. Disposition kinetics, renal clearance and urinary excretion of cefixime in adolescent Pakistani boys - DRUG ANALYSIS REPORT. JPMA. The Journal of the Pakistan Medical Association. 2019 Mar; 69(3):367-372. doi: NULL. [PMID: 30890829]
  • Mohammad Dehghani, Navid Nasirizadeh, Mohammad Esmail Yazdanshenas. Determination of cefixime using a novel electrochemical sensor produced with gold nanowires/graphene oxide/electropolymerized molecular imprinted polymer. Materials science & engineering. C, Materials for biological applications. 2019 Mar; 96(?):654-660. doi: 10.1016/j.msec.2018.12.002. [PMID: 30606577]
  • Kristie L Connolly, Ann E Eakin, Carolina Gomez, Blaire L Osborn, Magnus Unemo, Ann E Jerse. Pharmacokinetic Data Are Predictive of In Vivo Efficacy for Cefixime and Ceftriaxone against Susceptible and Resistant Neisseria gonorrhoeae Strains in the Gonorrhea Mouse Model. Antimicrobial agents and chemotherapy. 2019 03; 63(3):. doi: 10.1128/aac.01644-18. [PMID: 30642924]
  • Lindley A Barbee, Seema U Nayak, Jeffrey L Blumer, Mary Ann OʼRiordan, Wesley Gray, Jonathan M Zenilman, Matthew R Golden, J McLeod Griffiss. A Phase 1 Pharmacokinetic and Safety Study of Extended-Duration, High-dose Cefixime for Cephalosporin-resistant Neisseria gonorrhoeae in the Pharynx. Sexually transmitted diseases. 2018 10; 45(10):677-683. doi: 10.1097/olq.0000000000000844. [PMID: 29624558]
  • Shaghufta Perveen, Naila Safdar, Gul-E-Saba Chaudhry, Azra Yasmin. Antibacterial evaluation of silver nanoparticles synthesized from lychee peel: individual versus antibiotic conjugated effects. World journal of microbiology & biotechnology. 2018 Jul; 34(8):118. doi: 10.1007/s11274-018-2500-1. [PMID: 30008019]
  • Jayaweera Arachchige Asela Sampath Jayaweera, Mohommed Reyes. Antimicrobial misuse in pediatric urinary tract infections: recurrences and renal scarring. Annals of clinical microbiology and antimicrobials. 2018 Jun; 17(1):27. doi: 10.1186/s12941-018-0279-4. [PMID: 29940982]
  • Saman Naghibi, Hamed Sahebi. Employment of modified Fe3 O4 nanoparticles using thermo-sensitive polymer for extraction and pre-concentration of cefexime in biological samples. Biomedical chromatography : BMC. 2018 Feb; 32(2):. doi: 10.1002/bmc.4082. [PMID: 28833295]
  • Li-Yang Cheng, Cheng-Zhang Yang, Hui-Zi Li, Min Li, Ai-Min Bai, Yu Ouyang, Yan-Jun Hu. Probing the interaction of cephalosporin with bovine serum albumin: A structural and comparative perspective. Luminescence : the journal of biological and chemical luminescence. 2018 Feb; 33(1):209-218. doi: 10.1002/bio.3403. [PMID: 28976065]
  • Muhammad Imran, Muhammad Raza Shah, Farhat Ullah, Shafi Ullah, Abdul Sadiq, Imdad Ali, Farid Ahmed, Waqas Nawaz. Double-tailed acyl glycoside niosomal nanocarrier for enhanced oral bioavailability of Cefixime. Artificial cells, nanomedicine, and biotechnology. 2017 Nov; 45(7):1440-1451. doi: 10.1080/21691401.2016.1246451. [PMID: 27822958]
  • Ying Shi, Qixiao Zhai, Dongyao Li, Bingyong Mao, Xiaoming Liu, Jianxin Zhao, Hao Zhang, Wei Chen. Restoration of cefixime-induced gut microbiota changes by Lactobacillus cocktails and fructooligosaccharides in a mouse model. Microbiological research. 2017 Jul; 200(?):14-24. doi: 10.1016/j.micres.2017.04.001. [PMID: 28527760]
  • Subhash Dhital, Jeevan Bahadur Sherchand, Bharat Mani Pokharel, Keshab Parajuli, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sundar Khadka, Sulochana Khatiwada, Basista Rijal. Antimicrobial susceptibility pattern of Shigella spp. isolated from children under 5 years of age attending tertiary care hospitals, Nepal along with first finding of ESBL-production. BMC research notes. 2017 Jun; 10(1):192. doi: 10.1186/s13104-017-2512-1. [PMID: 28583187]
  • Farhad Akhgari, Naser Samadi, Khalil Farhadi. Fluorescent Carbon Dot as Nanosensor for Sensitive and Selective Detection of Cefixime Based on Inner Filter Effect. Journal of fluorescence. 2017 May; 27(3):921-927. doi: 10.1007/s10895-017-2027-0. [PMID: 28078632]
  • Preeti Kalia, Neelima R Kumar, Kusum Harjai. Studies on the therapeutic effect of propolis along with standard antibacterial drug in Salmonella enterica serovar Typhimurium infected BALB/c mice. BMC complementary and alternative medicine. 2016 Nov; 16(1):485. doi: 10.1186/s12906-016-1474-5. [PMID: 27887651]
  • Carlos Stambolsky, Soledad Rodríguez-Benítez, José Luis Gutiérrez-Pérez, Daniel Torres-Lagares, Jenifer Martín-González, Juan José Segura-Egea. Histologic characterization of regenerated tissues after pulp revascularization of immature dog teeth with apical periodontitis using tri-antibiotic paste and platelet-rich plasma. Archives of oral biology. 2016 Nov; 71(?):122-128. doi: 10.1016/j.archoralbio.2016.07.007. [PMID: 27491082]
  • Tulin Demir, Mumtaz Dadali. Recurrent complicated urinary tract infection due to rare pathogen Sphingomonas paucimobilis: contamination or real deal?. Le infezioni in medicina. 2016 Sep; 24(3):241-4. doi: NULL. [PMID: 27668907]
  • Muhammad Imran, Muhammad Raza Shah, Farhat Ullah, Shafi Ullah, Abdelbary M A Elhissi, Waqas Nawaz, Farid Ahmad, Abdul Sadiq, Imdad Ali. Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime. International journal of pharmaceutics. 2016 May; 505(1-2):122-32. doi: 10.1016/j.ijpharm.2016.03.042. [PMID: 27050867]
  • Alexandre Malmartel, Christian Ghasarossian. Bacterial resistance in urinary tract infections in patients with diabetes matched with patients without diabetes. Journal of diabetes and its complications. 2016 May; 30(4):705-9. doi: 10.1016/j.jdiacomp.2016.01.005. [PMID: 26851821]
  • Lihui Zhang, Baosheng Liu, Zhiyun Li, Ying Guo. Comparative studies on the interaction of cefixime with bovine serum albumin by fluorescence quenching spectroscopy and synchronous fluorescence spectroscopy. Luminescence : the journal of biological and chemical luminescence. 2015 Aug; 30(5):686-92. doi: 10.1002/bio.2805. [PMID: 25351241]
  • Li Wang, Changyuan Wang, Qi Liu, Qiang Meng, Xiaokui Huo, Pengyuan Sun, Xiaobo Yang, Huijun Sun, Yuhong Zhen, Jinyong Peng, Xiaochi Ma, Kexin Liu. PEPT1- and OAT1/3-mediated drug-drug interactions between bestatin and cefixime in vivo and in vitro in rats, and in vitro in human. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2014 Oct; 63(?):77-86. doi: 10.1016/j.ejps.2014.06.019. [PMID: 25016073]
  • Mehmet Lütfi Yola, Tanju Eren, Necip Atar. Molecularly imprinted electrochemical biosensor based on Fe@Au nanoparticles involved in 2-aminoethanethiol functionalized multi-walled carbon nanotubes for sensitive determination of cefexime in human plasma. Biosensors & bioelectronics. 2014 Oct; 60(?):277-85. doi: 10.1016/j.bios.2014.04.045. [PMID: 24832202]
  • Muhammad Sirajuddin, Saqib Ali, Vickie McKee, Manzar Sohail, Hammad Pasha. Potentially bioactive organotin(IV) compounds: synthesis, characterization, in vitro bioactivities and interaction with SS-DNA. European journal of medicinal chemistry. 2014 Sep; 84(?):343-63. doi: 10.1016/j.ejmech.2014.07.028. [PMID: 25036793]
  • Somnath D Bhinge, Sharangouda M Malipatil, Lalit V Sonawane. Bioanalytical method development and validation for simultaneous estimation of cefixime and dicloxacillin by RP-HPLC in human plasma. Acta chimica Slovenica. 2014; 61(3):580-6. doi: NULL. [PMID: 25286213]
  • V V Rafal'skiĭ, E V Dovgan', Iu V Kozyrev, T A Gustovarova, S V Khlybova, A V Novoselova, N G Filippenko, D G Likhikh. [The efficacy and safety of cefixime and amoxicillin/clavulanate in the treatment of asymptomatic bacteriuria in pregnant women: a randomized, prospective, multicenter study]. Urologiia (Moscow, Russia : 1999). 2013 Sep; ?(5):24, 26-8. doi: . [PMID: 24437236]
  • N Wolff, I Indaburu, F Muller, N Mariescu Depaire. [Purple urine bag syndrome…]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2013 Jun; 23(8):538-9. doi: 10.1016/j.purol.2013.03.017. [PMID: 23725585]
  • Ken Grime, Stuart W Paine. Species differences in biliary clearance and possible relevance of hepatic uptake and efflux transporters involvement. Drug metabolism and disposition: the biological fate of chemicals. 2013 Feb; 41(2):372-8. doi: 10.1124/dmd.112.049312. [PMID: 23139379]
  • Morike Ngoe Mokube, Julius Atashili, Gregory Edie Halle-Ekane, George M Ikomey, Peter M Ndumbe. Bacteriuria amongst pregnant women in the Buea Health District, Cameroon: prevalence, predictors, antibiotic susceptibility patterns and diagnosis. PloS one. 2013; 8(8):e71086. doi: 10.1371/journal.pone.0071086. [PMID: 23976983]
  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
  • Abbas Khan, Zafar Iqbal, Muhammad Imran Khan, Khalid Javed, Abad Khan, Lateef Ahmad, Yasar Shah, Fazli Nasir. Simultaneous determination of cefdinir and cefixime in human plasma by RP-HPLC/UV detection method: Method development, optimization, validation, and its application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Aug; 879(24):2423-9. doi: 10.1016/j.jchromb.2011.06.040. [PMID: 21782531]
  • V V Rafal'skiĭ, E V Divgan', A V Derevitskiĭ. [Cefixim: clinical pharmacology and role in therapy of urogenital infections]. Urologiia (Moscow, Russia : 1999). 2011 Mar; ?(2):63-6. doi: . [PMID: 21818869]
  • Rajeev Jain, Vinod K Gupta, N Jadon, K Radhapyari. Voltammetric determination of cefixime in pharmaceuticals and biological fluids. Analytical biochemistry. 2010 Dec; 407(1):79-88. doi: 10.1016/j.ab.2010.07.027. [PMID: 20678464]
  • John R Brill. Diagnosis and treatment of urethritis in men. American family physician. 2010 Apr; 81(7):873-8. doi: NULL. [PMID: 20353145]
  • S Faure, A Perrin-Guyomard, J M Delmas, P Chatre, M Laurentie. Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. Antimicrobial agents and chemotherapy. 2010 Jan; 54(1):164-9. doi: 10.1128/aac.00310-09. [PMID: 19901088]
  • Emirhan Nemutlu, Sedef Kir, Doruk Katlan, M Sinan Beksaç. Simultaneous multiresponse optimization of an HPLC method to separate seven cephalosporins in plasma and amniotic fluid: application to validation and quantification of cefepime, cefixime and cefoperazone. Talanta. 2009 Nov; 80(1):117-26. doi: 10.1016/j.talanta.2009.06.034. [PMID: 19782200]
  • Xiaofan Sui, Jin Sun, Haiyan Li, Yongjun Wang, Jianfang Liu, Xiaohong Liu, Wenping Zhang, Lijiang Chen, Zhonggui He. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry. 2009 Nov; 44(11):4455-60. doi: 10.1016/j.ejmech.2009.06.004. [PMID: 19586686]
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  • April Barbour, Stephan Schmidt, Sreedharan Nair Sabarinath, Maria Grant, Christoph Seubert, Donna Skee, Bindu Murthy, Hartmut Derendorf. Soft-tissue penetration of ceftobiprole in healthy volunteers determined by in vivo microdialysis. Antimicrobial agents and chemotherapy. 2009 Jul; 53(7):2773-6. doi: 10.1128/aac.01409-08. [PMID: 19364847]
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  • Yukio Kato, Tomoko Sugiura, Yasuhito Nakadera, Mikihiro Sugiura, Yoshiyuki Kubo, Takashi Sato, Akihiro Harada, Akira Tsuji. Investigation of the role of oligopeptide transporter PEPT1 and sodium/glucose cotransporter SGLT1 in intestinal absorption of their substrates using small GTP-binding protein Rab8-null mice. Drug metabolism and disposition: the biological fate of chemicals. 2009 Mar; 37(3):602-7. doi: 10.1124/dmd.108.023689. [PMID: 19074526]
  • V V Pisarev, K V Zaĭtseva, L B Smirnova, V G Belolipetskaia, D A Kibal'chich, I E Koltunov. [Determination of cefixime blood plasma levels by HPLC]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2009; 54(7-8):37-40. doi: NULL. [PMID: 20201402]
  • Ali Reza Nateghian, Joan L Robinson, Shahab Mohandessi, Nakysa Hooman. Resistance pattern of breakthrough urinary tract infections in children on antibiotic prophylaxis. Journal of infection and public health. 2009; 2(3):147-52. doi: 10.1016/j.jiph.2009.08.002. [PMID: 20701875]
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