malonic acid (BioDeep_00000405337)
Main id: BioDeep_00000002855
PANOMIX_OTCML-2023
代谢物信息卡片
Propanedioic acid
化学式: C3H4O4 (104.01095839999999)
中文名称: 丙二酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(=O)O)C(=O)O
InChI: InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
描述信息
An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
同义名列表
3 个代谢物同义名
数据库引用编号
24 个数据库交叉引用编号
- ChEBI: CHEBI:30794
- KEGG: C00383
- PubChem: 867
- DrugBank: DB02175
- ChEMBL: CHEMBL7942
- LipidMAPS: LMFA01170041
- CAS: 141-82-2
- MoNA: MoNA037952
- MoNA: MoNA034268
- MoNA: MoNA034267
- MoNA: MoNA034265
- MoNA: FiehnHILIC001311
- MoNA: HMDB0000691_ms_ms_960
- MoNA: HMDB0000691_ms_ms_959
- MoNA: HMDB0000691_ms_ms_958
- MetaboLights: MTBLC30794
- ChEBI: CHEBI:15792
- PubChem: 3673
- KNApSAcK: C00001193
- PDB-CCD: MLA
- PDB-CCD: MLI
- 3DMET: B00098
- NIKKAJI: J2.541K
- RefMet: Malonic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shubo Zhang, Wenfang Gao, Lina Xie, Guogang Zhang, Zimin Wei, Jie Li, Caihong Song, Mingkai Chang. Malonic acid shapes bacterial community dynamics in compost to promote carbon sequestration and humic substance synthesis.
Chemosphere.
2024 Feb; 350(?):141092. doi:
10.1016/j.chemosphere.2023.141092. [PMID: 38169202] - Milica N Dimitrijević Stojanović, Andjela A Franich, Milena M Jurišević, Nevena M Gajović, Nebojša N Arsenijević, Ivan P Jovanović, Bojan S Stojanović, Slobodanka Lj Mitrović, Jakob Kljun, Snežana Rajković, Marija D Živković. Platinum(II) complexes with malonic acids: Synthesis, characterization, in vitro and in vivo antitumor activity and interactions with biomolecules.
Journal of inorganic biochemistry.
2022 06; 231(?):111773. doi:
10.1016/j.jinorgbio.2022.111773. [PMID: 35279446] - Sarah Snanoudj, Stéphanie Torre, Bénédicte Sudrié-Arnaud, Lenaig Abily-Donval, Alice Goldenberg, Gajja S Salomons, Stéphane Marret, Soumeya Bekri, Abdellah Tebani. Heterogenous Clinical Landscape in a Consanguineous Malonic Aciduria Family.
International journal of molecular sciences.
2021 Nov; 22(23):. doi:
10.3390/ijms222312633. [PMID: 34884438] - Randy J Chandler, Leah E Venturoni, Jing Liao, Brandon T Hubbard, Jessica L Schneller, Victoria Hoffmann, Susana Gordo, Shengwen Zang, Chih-Wei Ko, Nelson Chau, Kyle Chiang, Mark A Kay, Adi Barzel, Charles P Venditti. Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Hepatology (Baltimore, Md.).
2021 06; 73(6):2223-2237. doi:
10.1002/hep.31570. [PMID: 32976669] - Gui-Ya Yang, Jun-Na Song, Ya-Qing Chang, Lei Wang, Yu-Guang Zheng, Dan Zhang, Long Guo. Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma.
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2021 Apr; 26(7):. doi:
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Scientific reports.
2020 11; 10(1):20408. doi:
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Biochimica et biophysica acta. Biomembranes.
2020 11; 1862(11):183433. doi:
10.1016/j.bbamem.2020.183433. [PMID: 32763244] - Seung Hoon Lee, Jung Min Ko, Mi-Kyoung Song, Junghan Song, Kyung Sun Park. A Korean child diagnosed with malonic aciduria harboring a novel start codon mutation following presentation with dilated cardiomyopathy.
Molecular genetics & genomic medicine.
2020 09; 8(9):e1379. doi:
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Proteomics. Clinical applications.
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2019 Aug; 57(8):715-723. doi:
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Journal of inherited metabolic disease.
2019 01; 42(1):107-116. doi:
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2018 Nov; 43(21):4288-4294. doi:
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Applied microbiology and biotechnology.
2018 Mar; 102(5):2351-2361. doi:
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Journal of hazardous materials.
2018 Jan; 341(?):290-296. doi:
10.1016/j.jhazmat.2017.07.033. [PMID: 28797944] - Christian Wölk, Christopher Janich, Udo Bakowsky, Andreas Langner, Gerald Brezesinski. Malonic acid based cationic lipids - The way to highly efficient DNA-carriers.
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2017 Oct; 248(?):20-34. doi:
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Bioorganic & medicinal chemistry.
2017 05; 25(9):2601-2608. doi:
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Journal of the American Society for Mass Spectrometry.
2017 05; 28(5):929-938. doi:
10.1007/s13361-017-1631-1. [PMID: 28315235] - Ben Fan, Yu-Long Li, Lei Li, Xiao-Jun Peng, Chen Bu, Xiao-Qin Wu, Rainer Borriss. Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions.
Journal of proteomics.
2017 02; 154(?):1-12. doi:
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10.1093/jxb/erw426. [PMID: 28204578] - Bibi Rafeiza Khan, Daniel J Wherritt, David Huhman, Lloyd W Sumner, Kent D Chapman, Elison B Blancaflor. Malonylation of Glucosylated N-Lauroylethanolamine: A NEW PATHWAY THAT DETERMINES N-ACYLETHANOLAMINE METABOLIC FATE IN PLANTS.
The Journal of biological chemistry.
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10.1002/ajmg.a.37590. [PMID: 26858006] - Xin Guan, Basil J Nikolau. AAE13 encodes a dual-localized malonyl-CoA synthetase that is crucial for mitochondrial fatty acid biosynthesis.
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Phytochemical analysis : PCA.
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10.1007/s12010-013-0334-8. [PMID: 23813405] - Ramakrishnan Karunakaran, Alison K East, Philip S Poole. Malonate catabolism does not drive N2 fixation in legume nodules.
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10.1016/j.plantsci.2012.09.001. [PMID: 23199681] - Trina Ghosh Dastidar, Anil N Netravali. 'Green' crosslinking of native starches with malonic acid and their properties.
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2012 Jan; 5(?):1. doi:
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Cell.
2011 Nov; 147(5):1118-31. doi:
10.1016/j.cell.2011.10.038. [PMID: 22118466] - Vikas S Padalkar, Vikas S Patil, N Sekar. Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding.
Chemistry Central journal.
2011 Nov; 5(?):72. doi:
10.1186/1752-153x-5-72. [PMID: 22067202] - Sung Ryeol Park, Mi Sun Ahn, Ah Reum Han, Je Won Park, Yeo Joon Yoon. Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering.
Journal of microbiology and biotechnology.
2011 Nov; 21(11):1143-6. doi:
10.4014/jmb.1108.08012. [PMID: 22127124] - Vinoy K Ramachandran, Alison K East, Ramakrishnan Karunakaran, J Allan Downie, Philip S Poole. Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics.
Genome biology.
2011 Oct; 12(10):R106. doi:
10.1186/gb-2011-12-10-r106. [PMID: 22018401] - Isabel Bondia-Pons, Emilia Nordlund, Ismo Mattila, Kati Katina, Anna-Marja Aura, Marjukka Kolehmainen, Matej Orešič, Hannu Mykkänen, Kaisa Poutanen. Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread.
Nutrition journal.
2011 Oct; 10(?):116. doi:
10.1186/1475-2891-10-116. [PMID: 22011443] - Sheila Alves, Cristina Nabais, Maria de Lurdes Simões Gonçalves, Margarida M Correia Dos Santos. Nickel speciation in the xylem sap of the hyperaccumulator Alyssum serpyllifolium ssp. lusitanicum growing on serpentine soils of northeast Portugal.
Journal of plant physiology.
2011 Oct; 168(15):1715-22. doi:
10.1016/j.jplph.2011.04.004. [PMID: 21664714] - Jason W Holder, Jil C Ulrich, Anthony C DeBono, Paul A Godfrey, Christopher A Desjardins, Jeremy Zucker, Qiandong Zeng, Alex L B Leach, Ion Ghiviriga, Christine Dancel, Thomas Abeel, Dirk Gevers, Chinnappa D Kodira, Brian Desany, Jason P Affourtit, Bruce W Birren, Anthony J Sinskey. Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development.
PLoS genetics.
2011 Sep; 7(9):e1002219. doi:
10.1371/journal.pgen.1002219. [PMID: 21931557] - Ahmed Alfares, Laura Dempsey Nunez, Khalid Al-Thihli, John Mitchell, Serge Melançon, Natascia Anastasio, Kevin C H Ha, Jacek Majewski, David S Rosenblatt, Nancy Braverman. Combined malonic and methylmalonic aciduria: exome sequencing reveals mutations in the ACSF3 gene in patients with a non-classic phenotype.
Journal of medical genetics.
2011 Sep; 48(9):602-5. doi:
10.1136/jmedgenet-2011-100230. [PMID: 21785126] - Elena A Kotova, Alexey V Kuzevanov, Alina A Pashkovskaya, Yuri N Antonenko. Selective permeabilization of lipid membranes by photodynamic action via formation of hydrophobic defects or pre-pores.
Biochimica et biophysica acta.
2011 Sep; 1808(9):2252-7. doi:
10.1016/j.bbamem.2011.05.018. [PMID: 21663731] - Hyun S Lillehoj, Duk K Kim, David M Bravo, Sung H Lee. Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens.
BMC proceedings.
2011 Jun; 5 Suppl 4(?):S34. doi:
10.1186/1753-6561-5-s4-s34. [PMID: 21645315] - Leonhard Jaitz, Bernhard Mueller, Gunda Koellensperger, Daniela Huber, Eva Oburger, Markus Puschenreiter, Stephan Hann. LC-MS analysis of low molecular weight organic acids derived from root exudation.
Analytical and bioanalytical chemistry.
2011 Jun; 400(8):2587-96. doi:
10.1007/s00216-010-4090-0. [PMID: 20711769] - Hui Chen, Hyun Uk Kim, Hua Weng, John Browse. Malonyl-CoA synthetase, encoded by ACYL ACTIVATING ENZYME13, is essential for growth and development of Arabidopsis.
The Plant cell.
2011 Jun; 23(6):2247-62. doi:
10.1105/tpc.111.086140. [PMID: 21642549] - Xianping Fang, Huasheng Ma, Dezhao Lu, Hong Yu, Wenguo Lai, Songlin Ruan. Comparative proteomics analysis of proteins expressed in the I-1 and I-2 internodes of strawberry stolons.
Proteome science.
2011 May; 9(?):26. doi:
10.1186/1477-5956-9-26. [PMID: 21569547] - Ya-Yun Wang, Yi-Fang Tsay. Arabidopsis nitrate transporter NRT1.9 is important in phloem nitrate transport.
The Plant cell.
2011 May; 23(5):1945-57. doi:
10.1105/tpc.111.083618. [PMID: 21571952] - M Flint Beal. Neuroprotective effects of creatine.
Amino acids.
2011 May; 40(5):1305-13. doi:
10.1007/s00726-011-0851-0. [PMID: 21448659] - So-Hyun Kim, Somi K Cho, Tae-Sun Min, Yujin Kim, Seung-Ok Yang, Hee-Su Kim, Sun-Hee Hyun, Hana Kim, Young-Suk Kim, Hyung-Kyoon Choi. Ameliorating effects of Mango (Mangifera indica L.) fruit on plasma ethanol level in a mouse model assessed with H-NMR based metabolic profiling.
Journal of clinical biochemistry and nutrition.
2011 May; 48(3):214-21. doi:
10.3164/jcbn.10-96. [PMID: 21562641] - Hong Lin, Binghai Lou, Jonathan M Glynn, Harshavardhan Doddapaneni, Edwin L Civerolo, Chuanwu Chen, Yongping Duan, Lijuan Zhou, Cheryl M Vahling. The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease.
PloS one.
2011 Apr; 6(4):e19135. doi:
10.1371/journal.pone.0019135. [PMID: 21552483] - Jian Zhao, David Huhman, Gail Shadle, Xian-Zhi He, Lloyd W Sumner, Yuhong Tang, Richard A Dixon. MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.
The Plant cell.
2011 Apr; 23(4):1536-55. doi:
10.1105/tpc.110.080804. [PMID: 21467581] - Batur Mamtimin, Halmurat Upur. [Plasma metabonomics analysis of tumor patients of phlegm-stasis syndrome].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2011 Apr; 31(4):492-5. doi:
. [PMID: 21608220] - Scott M Damrauer, Peter Studer, Cleide G da Silva, Christopher R Longo, Haley E Ramsey, Eva Csizmadia, Gautam V Shrikhande, Salvatore T Scali, Towia A Libermann, Manoj K Bhasin, Christiane Ferran. A20 modulates lipid metabolism and energy production to promote liver regeneration.
PloS one.
2011 Mar; 6(3):e17715. doi:
10.1371/journal.pone.0017715. [PMID: 21437236] - Nikolaos Psychogios, David D Hau, Jun Peng, An Chi Guo, Rupasri Mandal, Souhaila Bouatra, Igor Sinelnikov, Ramanarayan Krishnamurthy, Roman Eisner, Bijaya Gautam, Nelson Young, Jianguo Xia, Craig Knox, Edison Dong, Paul Huang, Zsuzsanna Hollander, Theresa L Pedersen, Steven R Smith, Fiona Bamforth, Russ Greiner, Bruce McManus, John W Newman, Theodore Goodfriend, David S Wishart. The human serum metabolome.
PloS one.
2011 Feb; 6(2):e16957. doi:
10.1371/journal.pone.0016957. [PMID: 21359215] - Pamela Strazzer, Flavia Guzzo, Marisa Levi. Correlated accumulation of anthocyanins and rosmarinic acid in mechanically stressed red cell suspensions of basil (Ocimum basilicum).
Journal of plant physiology.
2011 Feb; 168(3):288-93. doi:
10.1016/j.jplph.2010.07.020. [PMID: 20943285] - Ali Ghasemzadeh, Hawa Z E Jaafar. Effect of CO(2) enrichment on synthesis of some primary and secondary metabolites in ginger (Zingiber officinale Roscoe).
International journal of molecular sciences.
2011 Feb; 12(2):1101-14. doi:
10.3390/ijms12021101. [PMID: 21541046] - Valeria Boeris, Cecilia Cassane, Jorge Wagner, Guillermo Picó. The formation of non-soluble complexes between polyethyleneimine-anions and their potential use to isolate enzymes.
Colloids and surfaces. B, Biointerfaces.
2011 Feb; 82(2):354-8. doi:
10.1016/j.colsurfb.2010.09.008. [PMID: 20932724] - Kathleen S Hering-Smith, Faith R Schiro, Ana M Pajor, L Lee Hamm. Calcium sensitivity of dicarboxylate transport in cultured proximal tubule cells.
American journal of physiology. Renal physiology.
2011 Feb; 300(2):F425-32. doi:
10.1152/ajprenal.00036.2010. [PMID: 21123491] - Wagner L Araújo, Adriano Nunes-Nesi, Sonia Osorio, Björn Usadel, Daniela Fuentes, Réka Nagy, Ilse Balbo, Martin Lehmann, Claudia Studart-Witkowski, Takayuki Tohge, Enrico Martinoia, Xavier Jordana, Fábio M Damatta, Alisdair R Fernie. Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture.
The Plant cell.
2011 Feb; 23(2):600-27. doi:
10.1105/tpc.110.081224. [PMID: 21307286] - Batur Mamtimin, Halmurat Upur, Fu-Hua Hao, Aynur Matsidik, Rena Rahim. Plasma metabonomic analysis with ¹H nuclear magnetic resonance revealing the relationship of different tumors and the disease homology theory of traditional Uyghur medicine.
Chinese journal of integrative medicine.
2011 Feb; 17(2):111-5. doi:
10.1007/s11655-011-0638-x. [PMID: 21390577] - Bimlesh Ojha, Gopal Das. Role of hydrophobic and polar interactions for BSA-amphiphile composites.
Chemistry and physics of lipids.
2011 Feb; 164(2):144-50. doi:
10.1016/j.chemphyslip.2010.12.004. [PMID: 21185815] - Mingsheng Qi, Dongping Wang, Carl A Bradley, Youfu Zhao. Genome sequence analyses of Pseudomonas savastanoi pv. glycinea and subtractive hybridization-based comparative genomics with nine pseudomonads.
PloS one.
2011 Jan; 6(1):e16451. doi:
10.1371/journal.pone.0016451. [PMID: 21304594] - Lothar Wissler, Francisco M Codoñer, Jenny Gu, Thorsten B H Reusch, Jeanine L Olsen, Gabriele Procaccini, Erich Bornberg-Bauer. Back to the sea twice: identifying candidate plant genes for molecular evolution to marine life.
BMC evolutionary biology.
2011 Jan; 11(?):8. doi:
10.1186/1471-2148-11-8. [PMID: 21226908] - Hideki Takahashi, Peter Buchner, Naoko Yoshimoto, Malcolm J Hawkesford, Shin-Han Shiu. Evolutionary relationships and functional diversity of plant sulfate transporters.
Frontiers in plant science.
2011; 2(?):119. doi:
10.3389/fpls.2011.00119. [PMID: 22629272] - Fabio Facchinelli, Andreas P M Weber. The metabolite transporters of the plastid envelope: an update.
Frontiers in plant science.
2011; 2(?):50. doi:
10.3389/fpls.2011.00050. [PMID: 22645538] - Nafiseh Darandeh, Ebrahim Hadavi. Effect of Pre-Harvest Foliar Application of Citric Acid and Malic Acid on Chlorophyll Content and Post-Harvest Vase Life of Lilium cv. Brunello.
Frontiers in plant science.
2011; 2(?):106. doi:
10.3389/fpls.2011.00106. [PMID: 22639626] - Andrea Bräutigam, Kaisa Kajala, Julia Wullenweber, Manuel Sommer, David Gagneul, Katrin L Weber, Kevin M Carr, Udo Gowik, Janina Mass, Martin J Lercher, Peter Westhoff, Julian M Hibberd, Andreas P M Weber. An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species.
Plant physiology.
2011 Jan; 155(1):142-56. doi:
10.1104/pp.110.159442. [PMID: 20543093]