Chrysophanic acid (BioDeep_00000398597)

PANOMIX_OTCML-2023

代谢物信息卡片

Chrysophanic acid

化学式: C15H10O4 (254.057906)
中文名称: 大黄酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC(=C2C(=C1)C(=O)C3=C(C2=O)C(=CC=C3)O)O
InChI: InChI=1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3

描述信息

relative retention time with respect to 9-anthracene Carboxylic Acid is 1.321
D009676 - Noxae > D009153 - Mutagens
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.322
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.318
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.324
Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.

同义名列表

2 个代谢物同义名

Chrysophanic acid; Chrysophanol

数据库引用编号

14 个数据库交叉引用编号

ChEBI: CHEBI:3687
PubChem: 10208
ChEMBL: CHEMBL41092
CAS: 481-74-3
MoNA: BML80948
MoNA: BML80947
MoNA: BML80946
MoNA: BML80945
MoNA: BML01181
MoNA: BML01172
MoNA: BML01163
MoNA: BML01132
MoNA: BML01120
medchemexpress: HY-13595

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

406 个相关的物种来源信息

1786036 Rumex pictus: 10.1016/0305-1978(93)90049-W
1231245 Cassia renigera:
346985 Senna obtusifolia:
53852 Cassia fistula:
508996 Cassia javanica:
948718 Senna sophera:
948717 Cassia roxburghii:
53923 Senna alata:
72402 Senna alexandrina:
162709 Cassia grandis:
1288009 Senna macranthera var. micans:
72401 Senna didymobotrya:
5691 Trypanosoma brucei:
1813207 Rhamnus nakaharae: 10.1021/NP50085A021
694413 Rheum delavayi:
137225 Rheum sublanceolatum: 10.1055/S-2008-1074562
2743666 Rheum racemiferum:
137221 Rheum palmatum:
137219 Rheum nanum: 10.1055/S-2008-1074562
268908 Salvia greggii:
1389495 Aloe castellorum: 10.1080/14786410802242851
1786032 Rumex chalepensis:
174651 Rumex japonicus:
346999 Senna siamea:
1137045 Vismia cayennensis: 10.1016/S0031-9422(00)83481-0
999598 Vismia guianensis:
392618 Cunila: 10.1007/S00299-018-2303-8
992784 Senna petersiana: 10.1016/S0367-326X(00)00155-6
346407 Senna quinquangulata:
162908 Senna lindheimeriana: 10.1016/0031-9422(92)80483-U
346959 Senna corymbosa: 10.1016/0031-9422(92)80483-U
281910 Sanguisorba alpina: 10.1016/0031-9422(92)80123-V
3621 Rheum rhabarbarum:
137228 Rheum wittrockii: 10.1016/0378-8741(84)90016-3
137220 Rheum officinale:
240184 Rheum spiciforme: 10.1016/0378-8741(84)90016-3
137224 Rheum reticulatum: 10.1016/0378-8741(84)90016-3
137223 Rheum pumilum: 10.1016/0378-8741(84)90016-3
205071 Rheum tataricum: 10.1016/0378-8741(84)90016-3
574896 Rheum altaicum: 10.1016/0378-8741(84)90016-3
137216 Rheum compactum: 10.1016/0378-8741(84)90016-3
46087 Rheum rhaponticum:
137217 Rheum hotaoense: 10.1016/0378-8741(84)90016-3
137227 Rheum undulatum:
284363 Rheum australe:
137218 Rheum likiangense: 10.1016/0378-8741(84)90016-3
240182 Rheum franzenbachii:
284362 Rheum alexandrae: 10.1016/0378-8741(84)90016-3
137226 Rheum tanguticum:
240183 Rheum kialense: 10.1016/0378-8741(84)90016-3
694412 Rheum acuminatum: 10.1016/0378-8741(84)90016-3
137697 Rheum nobile: 10.1016/0378-8741(84)90016-3
346998 Senna septemtrionalis:
1977557 Senna singueana:
346974 Senna italica:
756587 Senna garrettiana: 10.1111/J.2042-7158.1974.TB09356.X
347003 Senna spectabilis: 10.1111/J.2042-7158.1974.TB09356.X
948713 Senna auriculata: 10.1111/J.2042-7158.1974.TB09356.X
346975 Senna macranthera: 10.1111/J.2042-7158.1974.TB09356.X
267261 Rosa villosa:
180472 Asahinea chrysantha: 10.1007/BF00638766
126820 Senna occidentalis:
3610 Rhamnus cathartica:
5544 Trichoderma harzianum:
13427 Cichorium intybus: 10.1016/S0278-6915(99)00027-7
39414 Plantago lanceolata: 10.1016/S0278-6915(99)00027-7
3888 Pisum sativum: 10.1016/S0278-6915(99)00027-7
4236 Lactuca sativa: 10.1016/S0278-6915(99)00027-7
101996 Plantago coronopus: 10.1016/S0278-6915(99)00027-7
29760 Vitis vinifera: 10.1016/S0278-6915(99)00027-7
52152 Elymus repens: 10.1016/S0278-6915(99)00027-7
35608 Artemisia annua: 10.1016/S0278-6915(99)00027-7
3617 Fagopyrum esculentum: 10.1016/S0278-6915(99)00027-7
5547 Trichoderma viride: 10.1139/V67-020
1129486 Picramnia antidesma:
588669 Aster tataricus: 10.1016/S0031-9422(98)00354-9
314325 Aster sedifolius: 10.1016/S0031-9422(98)00354-9
681474 Picramnia latifolia:
76025 Fallopia multiflora: 10.1002/PTR.2358
280022 Rhamnus prinoides: 10.1002/(SICI)1099-1565(199903/04)10:2<69::AID-PCA447>3.0.CO;2-4
1390085 Ventilago denticulata:
273505 Rumex abyssinicus:
174652 Rumex nepalensis:
174649 Rumex crispus:
25641 Aloe: 10.1002/JPS.2600580211
2686326 Picramnia hirsuta:
105902 Rhamnus davurica: 10.1021/NP010030V
108868 Ventilago leiocarpa: 10.1021/NP000569D
749552 Boeremia foveata: 10.1042/BJ0980112
278676 Rumex cristatus: 10.1042/BJ0980112
1813065 Rhamnus pallasii: 10.1007/BF00574350
40695 Trichoderma polysporum: 10.1016/S0031-9422(00)81684-2
1819798 Rhamnus wightii: 10.1016/0031-9422(91)83502-C
1813053 Rhamnus formosana: 10.1016/0031-9422(90)85356-K
362788 Senna tora:
424903 Osmanthus armatus: 10.1080/14786410802689713
948714 Senna sulfurea: 10.1055/S-0028-1097458
1842781 Senna gaudichaudii: 10.1055/S-0028-1097458
1526916 Chamaecrista pumila: 10.1016/S0367-326X(99)00041-6
1813059 Rhamnus kurdica: 10.3109/13880209209053982
1778787 Rhamnus punctata: 10.3109/13880209209053982
38448 Monilinia fructicola:
71662 Monodictys: 10.1248/CPB.55.1097
117978 Dendrobium thyrsiflorum: 10.1016/J.PHYTOCHEM.2005.04.001
1351827 Rumex alpinus:
242528 Rumex scutatus: 10.1515/ZNC-1997-9-1014
555937 Kniphofia ensifolia: 10.1016/J.BMC.2013.11.032
555898 Kniphofia caulescens: 10.1016/0305-1978(88)90089-0
555912 Kniphofia linearifolia: 10.1016/0305-1978(88)90089-0
214838 Kniphofia foliosa:
41241 Rumex acetosa:
137229 Rumex patientia:
3620 Rheum: 10.1002/(SICI)1099-0801(199807/08)12:4<193::AID-BMC729>3.0.CO;2-7
139234 Pyrenophora catenaria: 10.1016/S0031-9422(00)91370-0
3618 Rumex: 10.1016/J.BMCL.2013.04.059
214840 Kniphofia insignis: 10.1016/0031-9422(86)80014-0
214843 Kniphofia schimperi: 10.1016/0031-9422(86)80014-0
214841 Kniphofia isoetifolia: 10.1016/0031-9422(86)80014-0
214842 Kniphofia pumila: 10.1016/0031-9422(86)80014-0
51475 Phormium tenax: 10.1021/NP50052A039
217990 Phormium cookianum: 10.1021/NP50052A039
1353961 Selaginella delicatula: 10.1007/S10600-011-0013-3
2686335 Alvaradoa haitiensis:
2686329 Alvaradoa jamaicensis:
1389501 Aloe ellenbeckii: 10.1016/S0031-9422(00)94771-X
1389509 Aloe harlana: 10.1016/S0031-9422(00)94771-X
1593063 Aloe camperi: 10.1016/S0031-9422(00)94771-X
1593069 Aloe debrana:
1593109 Aloe sinana: 10.1016/S0031-9422(00)94771-X
1813110 Aloe calidophila: 10.1016/S0031-9422(00)94771-X
1593106 Aloe schelpei: 10.1016/S0031-9422(00)94771-X
1128790 Aloe globuligemma:
1128792 Aloe greatheadii: 10.1016/S0031-9422(00)94771-X
1811902 Aloe rivae:
1389490 Aloe aculeata: 10.1016/S0031-9422(00)94771-X
1389516 Aloe megalacantha: 10.1016/S0031-9422(00)94771-X
1389513 Aloe kilifiensis: 10.1016/S0031-9422(00)94771-X
1593091 Aloe macrocarpa: 10.1016/S0031-9422(00)94771-X
1593086 Aloe lateritia: 10.1016/S0031-9422(00)94771-X
45385 Aloe arborescens:
1389527 Aloe trichosantha: 10.1016/S0031-9422(00)94771-X
1593107 Aloe secundiflora: 10.1016/S0031-9422(00)94771-X
1188283 Aloe chabaudii: 10.1016/S0031-9422(00)94771-X
438378 Ramularia uredinicola: 10.1021/NP800138Y
49696 Asphodeline lutea: 10.1007/S10600-010-9604-7
1226760 Berchemia floribunda: 10.1248/CPB.56.1248
928054 Eremurus chinensis: 10.1021/NP9904915
1128810 Aloe succotrina:
888276 Aloidendron dichotomum: 10.1016/S0176-1617(11)81144-2
34199 Aloe vera:
1331516 Aloe broomii: 10.1016/S0176-1617(11)81144-2
117798 Aloe ferox: 10.1016/S0176-1617(11)81144-2
48875 Aloe bakeri:
247124 Aloe humilis: 10.1016/S0176-1617(11)81144-2
117806 Aloe nyeriensis: 10.1016/S0176-1617(11)81144-2
1813113 Aloe elgonica: 10.1016/S0176-1617(11)81144-2
1593115 Aloe volkensii: 10.1016/S0176-1617(11)81144-2
1331519 Aloe vaombe: 10.1016/0305-1978(94)90102-3
1593082 Aloe khamiesensis: 10.1016/0305-1978(94)90102-3
49726 Aloe purpurea: 10.1016/0305-1978(95)00063-1
210981 Aloe occidentalis: 10.1016/0305-1978(95)00063-1
212387 Aloe macra: 10.1016/0305-1978(95)00063-1
142771 Entodon luridus: 10.4268/CJCMM20161809
999591 Psorospermum febrifugum: 10.1016/0031-9422(83)83041-6
38033 Chaetomium globosum: 10.1055/S-2002-34415
72655 Xanthorrhoea australis: 10.1071/CH9740331
1155789 Aloe maculata:
106720 Ventilago viminalis: 10.1071/CH9630695
1133552 Asphodeline damascena: 10.1016/0031-9422(85)80028-5
365555 Shorea worthingtonii: 10.1016/S0031-9422(00)91468-7
2601745 Senna longiracemosa: 10.1016/S0031-9422(00)95104-5
198768 Harungana madagascariensis:
1508160 Ligusticum striatum: 10.4268/CJCMM20111013
2689076 Ligusticum chuanxiong: 10.4268/CJCMM20111013
34190 Hemerocallis fulva: 10.3109/13880209009082803
526195 Euphorbia hylonoma: 10.1016/J.FITOTE.2006.09.019
2269067 Asphodeline taurica: 10.1016/0031-9422(89)80076-7
694414 Rheum palaestinum: 10.1016/S0031-9422(00)00341-1
2511937 Bulbine abyssinica: 10.1016/J.TET.2005.01.040
102750 Ageratina altissima: 10.1515/ZNB-2005-0916
103745 Chromolaena odorata: 10.1515/ZNB-2005-0916
158314 Polyporus umbellatus: 10.1007/S10600-009-9229-X
347010 Senna villosa: 10.1016/S0031-9422(00)94783-6
1348480 Vismia latifolia: 10.1002/1097-458X(200012)38:12<1027::AID-MRC777>3.0.CO;2-3
1497607 Asphodelus fistulosus:
1423376 Asphodelus tenuifolius: 10.1016/S0031-9422(00)90193-6
49698 Asphodelus aestivus: 10.1016/S0031-9422(00)90193-6
207931 Asphodelus albus: 10.1055/S-0028-1097723
59067 Ruscus aculeatus: 10.1007/S40278-014-1868-4
2686319 Picramnia sellowii: 10.1021/NP070560C
106683 Karwinskia humboldtiana: 10.1016/S0031-9422(00)88492-7
1006352 Rumex dentatus: 10.1039/P19750000689
66098 Simethis mattiazzii: 10.3109/13880208509070680
1883 Streptomyces: 10.1038/JA.2008.63
948715 Chamaecrista mimosoides: 10.1055/S-2007-969598
117953 Dendrobium fimbriatum: 10.5530/PJ.2014.3.6
2382096 Strossmayeria bakeriana: 10.1016/S0031-9422(00)88708-7
2182550 Abrus melanospermus: 10.1055/S-2007-971214
28573 Talaromyces islandicus: 10.3390/BIOM9020068
106689 Maesopsis eminii: 10.1055/S-2007-969586
263405 Trirhabda geminata: 10.1515/ZNC-1996-3-417
1786036 Rumex pictus: 10.1016/0305-1978(93)90049-W
1231245 Cassia renigera:
346985 Senna obtusifolia:
53852 Cassia fistula:
508996 Cassia javanica:
948718 Senna sophera:
948717 Cassia roxburghii:
53923 Senna alata:
72402 Senna alexandrina:
162709 Cassia grandis:
1288009 Senna macranthera var. micans:
72401 Senna didymobotrya:
5691 Trypanosoma brucei:
1813207 Rhamnus nakaharae: 10.1021/NP50085A021
694413 Rheum delavayi:
137225 Rheum sublanceolatum: 10.1055/S-2008-1074562
2743666 Rheum racemiferum:
137221 Rheum palmatum:
137219 Rheum nanum: 10.1055/S-2008-1074562
268908 Salvia greggii:
1389495 Aloe castellorum: 10.1080/14786410802242851
1786032 Rumex chalepensis:
174651 Rumex japonicus:
346999 Senna siamea:
1137045 Vismia cayennensis: 10.1016/S0031-9422(00)83481-0
999598 Vismia guianensis:
392618 Cunila: 10.1007/S00299-018-2303-8
992784 Senna petersiana: 10.1016/S0367-326X(00)00155-6
346407 Senna quinquangulata:
162908 Senna lindheimeriana: 10.1016/0031-9422(92)80483-U
346959 Senna corymbosa: 10.1016/0031-9422(92)80483-U
281910 Sanguisorba alpina: 10.1016/0031-9422(92)80123-V
3621 Rheum rhabarbarum:
137228 Rheum wittrockii: 10.1016/0378-8741(84)90016-3
137220 Rheum officinale:
240184 Rheum spiciforme: 10.1016/0378-8741(84)90016-3
137224 Rheum reticulatum: 10.1016/0378-8741(84)90016-3
137223 Rheum pumilum: 10.1016/0378-8741(84)90016-3
205071 Rheum tataricum: 10.1016/0378-8741(84)90016-3
574896 Rheum altaicum: 10.1016/0378-8741(84)90016-3
137216 Rheum compactum: 10.1016/0378-8741(84)90016-3
46087 Rheum rhaponticum:
137217 Rheum hotaoense: 10.1016/0378-8741(84)90016-3
137227 Rheum undulatum:
284363 Rheum australe:
137218 Rheum likiangense: 10.1016/0378-8741(84)90016-3
240182 Rheum franzenbachii:
284362 Rheum alexandrae: 10.1016/0378-8741(84)90016-3
137226 Rheum tanguticum:
240183 Rheum kialense: 10.1016/0378-8741(84)90016-3
694412 Rheum acuminatum: 10.1016/0378-8741(84)90016-3
137697 Rheum nobile: 10.1016/0378-8741(84)90016-3
346998 Senna septemtrionalis:
1977557 Senna singueana:
346974 Senna italica:
756587 Senna garrettiana: 10.1111/J.2042-7158.1974.TB09356.X
347003 Senna spectabilis: 10.1111/J.2042-7158.1974.TB09356.X
948713 Senna auriculata: 10.1111/J.2042-7158.1974.TB09356.X
346975 Senna macranthera: 10.1111/J.2042-7158.1974.TB09356.X
267261 Rosa villosa:
180472 Asahinea chrysantha: 10.1007/BF00638766
126820 Senna occidentalis:
3610 Rhamnus cathartica:
5544 Trichoderma harzianum:
13427 Cichorium intybus: 10.1016/S0278-6915(99)00027-7
39414 Plantago lanceolata: 10.1016/S0278-6915(99)00027-7
3888 Pisum sativum: 10.1016/S0278-6915(99)00027-7
4236 Lactuca sativa: 10.1016/S0278-6915(99)00027-7
101996 Plantago coronopus: 10.1016/S0278-6915(99)00027-7
29760 Vitis vinifera: 10.1016/S0278-6915(99)00027-7
52152 Elymus repens: 10.1016/S0278-6915(99)00027-7
35608 Artemisia annua: 10.1016/S0278-6915(99)00027-7
3617 Fagopyrum esculentum: 10.1016/S0278-6915(99)00027-7
5547 Trichoderma viride: 10.1139/V67-020
1129486 Picramnia antidesma:
588669 Aster tataricus: 10.1016/S0031-9422(98)00354-9
314325 Aster sedifolius: 10.1016/S0031-9422(98)00354-9
681474 Picramnia latifolia:
76025 Fallopia multiflora: 10.1002/PTR.2358
280022 Rhamnus prinoides: 10.1002/(SICI)1099-1565(199903/04)10:2<69::AID-PCA447>3.0.CO;2-4
1390085 Ventilago denticulata:
273505 Rumex abyssinicus:
174652 Rumex nepalensis:
174649 Rumex crispus:
25641 Aloe: 10.1002/JPS.2600580211
2686326 Picramnia hirsuta:
105902 Rhamnus davurica: 10.1021/NP010030V
108868 Ventilago leiocarpa: 10.1021/NP000569D
749552 Boeremia foveata: 10.1042/BJ0980112
278676 Rumex cristatus: 10.1042/BJ0980112
1813065 Rhamnus pallasii: 10.1007/BF00574350
40695 Trichoderma polysporum: 10.1016/S0031-9422(00)81684-2
1819798 Rhamnus wightii: 10.1016/0031-9422(91)83502-C
1813053 Rhamnus formosana: 10.1016/0031-9422(90)85356-K
362788 Senna tora:
424903 Osmanthus armatus: 10.1080/14786410802689713
948714 Senna sulfurea: 10.1055/S-0028-1097458
1842781 Senna gaudichaudii: 10.1055/S-0028-1097458
1526916 Chamaecrista pumila: 10.1016/S0367-326X(99)00041-6
1813059 Rhamnus kurdica: 10.3109/13880209209053982
1778787 Rhamnus punctata: 10.3109/13880209209053982
38448 Monilinia fructicola:
71662 Monodictys: 10.1248/CPB.55.1097
117978 Dendrobium thyrsiflorum: 10.1016/J.PHYTOCHEM.2005.04.001
1351827 Rumex alpinus:
242528 Rumex scutatus: 10.1515/ZNC-1997-9-1014
555937 Kniphofia ensifolia: 10.1016/J.BMC.2013.11.032
555898 Kniphofia caulescens: 10.1016/0305-1978(88)90089-0
555912 Kniphofia linearifolia: 10.1016/0305-1978(88)90089-0
214838 Kniphofia foliosa:
41241 Rumex acetosa:
137229 Rumex patientia:
3620 Rheum: 10.1002/(SICI)1099-0801(199807/08)12:4<193::AID-BMC729>3.0.CO;2-7
139234 Pyrenophora catenaria: 10.1016/S0031-9422(00)91370-0
3618 Rumex: 10.1016/J.BMCL.2013.04.059
214840 Kniphofia insignis: 10.1016/0031-9422(86)80014-0
214843 Kniphofia schimperi: 10.1016/0031-9422(86)80014-0
214841 Kniphofia isoetifolia: 10.1016/0031-9422(86)80014-0
214842 Kniphofia pumila: 10.1016/0031-9422(86)80014-0
51475 Phormium tenax: 10.1021/NP50052A039
217990 Phormium cookianum: 10.1021/NP50052A039
1353961 Selaginella delicatula: 10.1007/S10600-011-0013-3
2686335 Alvaradoa haitiensis:
2686329 Alvaradoa jamaicensis:
1389501 Aloe ellenbeckii: 10.1016/S0031-9422(00)94771-X
1389509 Aloe harlana: 10.1016/S0031-9422(00)94771-X
1593063 Aloe camperi: 10.1016/S0031-9422(00)94771-X
1593069 Aloe debrana:
1593109 Aloe sinana: 10.1016/S0031-9422(00)94771-X
1813110 Aloe calidophila: 10.1016/S0031-9422(00)94771-X
1593106 Aloe schelpei: 10.1016/S0031-9422(00)94771-X
1128790 Aloe globuligemma:
1128792 Aloe greatheadii: 10.1016/S0031-9422(00)94771-X
1811902 Aloe rivae:
1389490 Aloe aculeata: 10.1016/S0031-9422(00)94771-X
1389516 Aloe megalacantha: 10.1016/S0031-9422(00)94771-X
1389513 Aloe kilifiensis: 10.1016/S0031-9422(00)94771-X
1593091 Aloe macrocarpa: 10.1016/S0031-9422(00)94771-X
1593086 Aloe lateritia: 10.1016/S0031-9422(00)94771-X
45385 Aloe arborescens:
1389527 Aloe trichosantha: 10.1016/S0031-9422(00)94771-X
1593107 Aloe secundiflora: 10.1016/S0031-9422(00)94771-X
1188283 Aloe chabaudii: 10.1016/S0031-9422(00)94771-X
438378 Ramularia uredinicola: 10.1021/NP800138Y
49696 Asphodeline lutea: 10.1007/S10600-010-9604-7
1226760 Berchemia floribunda: 10.1248/CPB.56.1248
928054 Eremurus chinensis: 10.1021/NP9904915
1128810 Aloe succotrina:
888276 Aloidendron dichotomum: 10.1016/S0176-1617(11)81144-2
34199 Aloe vera:
1331516 Aloe broomii: 10.1016/S0176-1617(11)81144-2
117798 Aloe ferox: 10.1016/S0176-1617(11)81144-2
48875 Aloe bakeri:
247124 Aloe humilis: 10.1016/S0176-1617(11)81144-2
117806 Aloe nyeriensis: 10.1016/S0176-1617(11)81144-2
1813113 Aloe elgonica: 10.1016/S0176-1617(11)81144-2
1593115 Aloe volkensii: 10.1016/S0176-1617(11)81144-2
1331519 Aloe vaombe: 10.1016/0305-1978(94)90102-3
1593082 Aloe khamiesensis: 10.1016/0305-1978(94)90102-3
49726 Aloe purpurea: 10.1016/0305-1978(95)00063-1
210981 Aloe occidentalis: 10.1016/0305-1978(95)00063-1
212387 Aloe macra: 10.1016/0305-1978(95)00063-1
142771 Entodon luridus: 10.4268/CJCMM20161809
999591 Psorospermum febrifugum: 10.1016/0031-9422(83)83041-6
38033 Chaetomium globosum: 10.1055/S-2002-34415
72655 Xanthorrhoea australis: 10.1071/CH9740331
1155789 Aloe maculata:
106720 Ventilago viminalis: 10.1071/CH9630695
1133552 Asphodeline damascena: 10.1016/0031-9422(85)80028-5
365555 Shorea worthingtonii: 10.1016/S0031-9422(00)91468-7
2601745 Senna longiracemosa: 10.1016/S0031-9422(00)95104-5
198768 Harungana madagascariensis:
1508160 Ligusticum striatum: 10.4268/CJCMM20111013
2689076 Ligusticum chuanxiong: 10.4268/CJCMM20111013
34190 Hemerocallis fulva: 10.3109/13880209009082803
526195 Euphorbia hylonoma: 10.1016/J.FITOTE.2006.09.019
2269067 Asphodeline taurica: 10.1016/0031-9422(89)80076-7
694414 Rheum palaestinum: 10.1016/S0031-9422(00)00341-1
2511937 Bulbine abyssinica: 10.1016/J.TET.2005.01.040
102750 Ageratina altissima: 10.1515/ZNB-2005-0916
103745 Chromolaena odorata: 10.1515/ZNB-2005-0916
158314 Polyporus umbellatus: 10.1007/S10600-009-9229-X
347010 Senna villosa: 10.1016/S0031-9422(00)94783-6
1348480 Vismia latifolia: 10.1002/1097-458X(200012)38:12<1027::AID-MRC777>3.0.CO;2-3
1497607 Asphodelus fistulosus:
1423376 Asphodelus tenuifolius: 10.1016/S0031-9422(00)90193-6
49698 Asphodelus aestivus: 10.1016/S0031-9422(00)90193-6
207931 Asphodelus albus: 10.1055/S-0028-1097723
59067 Ruscus aculeatus: 10.1007/S40278-014-1868-4
2686319 Picramnia sellowii: 10.1021/NP070560C
106683 Karwinskia humboldtiana: 10.1016/S0031-9422(00)88492-7
1006352 Rumex dentatus: 10.1039/P19750000689
66098 Simethis mattiazzii: 10.3109/13880208509070680
1883 Streptomyces: 10.1038/JA.2008.63
948715 Chamaecrista mimosoides: 10.1055/S-2007-969598
117953 Dendrobium fimbriatum: 10.5530/PJ.2014.3.6
2382096 Strossmayeria bakeriana: 10.1016/S0031-9422(00)88708-7
2182550 Abrus melanospermus: 10.1055/S-2007-971214
28573 Talaromyces islandicus: 10.3390/BIOM9020068
106689 Maesopsis eminii: 10.1055/S-2007-969586
263405 Trirhabda geminata: 10.1515/ZNC-1996-3-417
714442 Ampelopsis Japonica: -
184783 Areca Catechu L.: -
2689076 Ligusticum chuanxiong Hort.: -
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Huang-Fei Jin, Qian-Xue Shen, Ying Shi, Fang-Ming Liu, Bin Wang, Jun Cao, Li-Hong Ye. Magnetic-stirring-enhanced mechanical amorphous dispersion extraction for the hydrophobic phytochemical constituents using an aqueous solution from a medicinal plant. Journal of pharmaceutical and biomedical analysis. 2024 Aug; 245(?):116191. doi: 10.1016/j.jpba.2024.116191. [PMID: 38728950]
吉 Deji, Jun Lan, Basangyangzong, Dawazhuoma. [Establishment and Optimization of Quality Standards for the Traditional Tibetan Medicine Preparation of Liuwei Nengxiao Pills]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2024 Mar; 55(2):425-432. doi: 10.12182/20240360102. [PMID: 38645843]
Razieh Amini, Shadi Moradi, Rezvan Najafi, Mehrdokht Mazdeh, Amir Taherkhani. BACE1 Inhibition Utilizing Organic Compounds Holds Promise as a Potential Treatment for Alzheimer's and Parkinson's Diseases. Oxidative medicine and cellular longevity. 2024; 2024(?):6654606. doi: 10.1155/2024/6654606. [PMID: 38425997]
Fang Zhang, Rui Wu, Yanfang Liu, Shu Dai, Xinyan Xue, Xiaohong Gong, Yunxia Li. Comparative Pharmacokinetic Study of Rhubarb Anthraquinones in Normal and Nonalcoholic Fatty Liver Disease Rats. European journal of drug metabolism and pharmacokinetics. 2024 Jan; 49(1):111-121. doi: 10.1007/s13318-023-00875-z. [PMID: 38112917]
Huijuan Lv, Jingjing Niu, Wenhao Pan, Yudong Wang, Lifang Wang, Meng Wang, Yali Shi, Guifang Zhang, Bandar Al Hamyari, Shaohua Wang, Xuefeng Li, Yanbin Shi. Stool-softening effect and action mechanism of free anthraquinones extracted from Rheum palmatum L. on water deficit-induced constipation in rats. Journal of ethnopharmacology. 2023 Oct; 319(Pt 3):117336. doi: 10.1016/j.jep.2023.117336. [PMID: 37907143]
H Wang, M Li, S Li, J Shi, L Huang, S Cheng, C Zou, H Yan. [Spectrum-effect relationship of total anthraquinone extract of Cassia seeds against fluorouracil-induced liver injury in mice]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2023 May; 43(5):825-831. doi: 10.12122/j.issn.1673-4254.2023.05.19. [PMID: 37313825]
Hanaa M Sayed, Mahmoud A Ramadan, Heba H Salem, Iqrar Ahmad, Harun Patel, Marwa A A Fayed. Phytochemical Investigation, In silico/In vivo Analgesic, and Anti-inflammatory Assessment of the Egyptian Cassia occidentalis L. Steroids. 2023 May; 196(?):109245. doi: 10.1016/j.steroids.2023.109245. [PMID: 37141980]
Su-Kang Kim, Ju-Yeon Ban, Hyungoo Kang, Sang-Il Park. Anti-Apoptotic Effect of Chrysophanol Isolated from Cassia tora Seed Extract on Blue-Light-Induced A2E-Loaded Human Retinal Pigment Epithelial Cells. International journal of molecular sciences. 2023 Apr; 24(7):. doi: 10.3390/ijms24076676. [PMID: 37047648]
Meng Zhang, Zhi-Xian Ding, Wei Huang, Jing Luo, Shu Ye, Sheng-Lin Hu, Peng Zhou, Biao Cai. Chrysophanol exerts a protective effect against Aβ25-35-induced Alzheimer's disease model through regulating the ROS/TXNIP/NLRP3 pathway. Inflammopharmacology. 2023 Mar; ?(?):. doi: 10.1007/s10787-023-01201-4. [PMID: 36976486]
Dongpeng Wang, Jufeng Duan, Xiao-Jing Chen, Kaiqi Liu, Yingying Guo, Run Shi, Sha Li, Ming Liu, Lijun Zhao, Bei Li, Hongtao Liu, Minglun Li, Yibin Feng, Hongliang Li, Xuanbin Wang. Pharmacokinetic characteristics of emodin in polygoni Multiflori Radix Praeparata. Journal of ethnopharmacology. 2023 Mar; 303(?):115945. doi: 10.1016/j.jep.2022.115945. [PMID: 36435407]
Lingling Wang, Guoying Zhou, Shuo Zhao, Yang Yang. Soluble protein content, bioactive compounds and the antioxidant activity in seeds of ten Rheum tanguticum lines from Qinghai-Tibet Plateau. Chemistry & biodiversity. 2023 Feb; ?(?):e202200901. doi: 10.1002/cbdv.202200901. [PMID: 36788177]
Jiajie Lu, Zhimin Miao, Yuhan Jiang, Weiyi Xia, Xian Wang, Yifeng Shi, Libin Ni, Sunlong Li, Jian Xiao, Sunren Sheng, Haiming Jin. Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis. Biochemical pharmacology. 2023 02; 208(?):115402. doi: 10.1016/j.bcp.2022.115402. [PMID: 36592706]
Maria Goretti de Vasconcelos Silva, Daniele Rodrigues de Lima, Jackelyne Alves Monteiro, Francisco Ernani Alves Magalhães. Anxiolytic-like effect of chrysophanol from Senna cana stem in adult zebrafish (Danio rerio). Natural product research. 2022 Sep; 36(17):4426-4430. doi: 10.1080/14786419.2021.1980788. [PMID: 34547943]
Aarti Sharma, Sonalika Bhalla, Sidharth Mehan. PI3K/AKT/mTOR signalling inhibitor chrysophanol ameliorates neurobehavioural and neurochemical defects in propionic acid-induced experimental model of autism in adult rats. Metabolic brain disease. 2022 08; 37(6):1909-1929. doi: 10.1007/s11011-022-01026-0. [PMID: 35687217]
Pengchegn Li, Xiaohan Zhu, Mi Xiao, Yanqi Su, Shanshan Yu, Jintian Tang, Hongkun Xue, Xu Cai. Rapid Isolation and Hypoglycemic Activity of Secondary Metabolites of Eurotium cristatum by High-Speed Countercurrent Chromatography. Journal of chromatographic science. 2022 Mar; ?(?):. doi: 10.1093/chromsci/bmac020. [PMID: 35325046]
Xinquan Li, Yaxun Cheng, Yunpeng Qin, Huawu Gao, Guangyun Wang, Hang Song, Yan Wang, Biao Cai. Chrysophanol exerts neuroprotective effects via interfering with endoplasmic reticulum stress apoptotic pathways in cell and animal models of Alzheimer's disease. The Journal of pharmacy and pharmacology. 2022 Jan; 74(1):32-40. doi: 10.1093/jpp/rgab148. [PMID: 34791341]
Xu Zhao, Dongge Qiao, Dongsheng Guan, Kun Wang, Yinglin Cui. Chrysophanol Ameliorates Hemin-Induced Oxidative Stress and Endoplasmic Reticulum Stress by Regulating MicroRNA-320-5p/Wnt3a Pathway in HT22 Cells. Oxidative medicine and cellular longevity. 2022; 2022(?):9399658. doi: 10.1155/2022/9399658. [PMID: 35936221]
Chwan-Fwu Lin, Shih-Yi Chuang, Tse-Hung Huang, Thi My Huyen Nguyen, Pei-Wen Wang, Ahmed Alalaiwe, Jia-You Fang. A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Jan; 145(?):112482. doi: 10.1016/j.biopha.2021.112482. [PMID: 34915669]
Wanlapa Nuankaew, Armad Heemman, Chatchai Wattanapiromsakul, Ji Heon Shim, Na Woo Kim, Tamanna Yasmin, Seo Yule Jeong, Youn Hee Nam, Bin Na Hong, Sukanya Dej-Adisai, Tong Ho Kang. Anti-insulin resistance effect of constituents from Senna siamea on zebrafish model, its molecular docking, and structure-activity relationships. Journal of natural medicines. 2021 Jun; 75(3):520-531. doi: 10.1007/s11418-021-01490-5. [PMID: 33620670]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Cheemalamarri Chandrasekhar, Hemshikha Rajpurohit, Kalpana Javaji, Madhusudana Kuncha, Aravind Setti, A Zehra Ali, Ashok K Tiwari, Sunil Misra, C Ganesh Kumar. Anti-hyperglycemic and genotoxic studies of 1-O-methyl chrysophanol, a new anthraquinone isolated from Amycolatopsis thermoflava strain SFMA-103. Drug and chemical toxicology. 2021 Mar; 44(2):148-160. doi: 10.1080/01480545.2018.1551406. [PMID: 30614298]
Ramasamy Harikrishnan, Gunapathy Devi, Chellam Balasundaram, Hien Van Doan, Sanchai Jaturasitha, Einar Ringø, Caterina Faggio. Effect of chrysophanic acid on immune response and immune genes transcriptomic profile in Catla catla against Aeromonas hydrophila. Scientific reports. 2021 01; 11(1):612. doi: 10.1038/s41598-020-79629-9. [PMID: 33436677]
Mingjia Gu, Lidan Lu, Qingxue Wei, Zhiwei Miao, Hang Zhang, Leiping Gao, Lejun Li. Improved oral bioavailability and anti-chronic renal failure activity of chrysophanol via mixed polymeric micelles. Journal of microencapsulation. 2021 Jan; 38(1):47-60. doi: 10.1080/02652048.2020.1849440. [PMID: 33175576]
Chan-Yen Kuo, Valeria Chiu, Po-Chun Hsieh, Chun-Yen Huang, S Joseph Huang, I-Shiang Tzeng, Fu-Ming Tsai, Mao-Liang Chen, Chien-Ting Liu, Yi-Ru Chen. Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis. Journal of pharmacological sciences. 2020 Nov; 144(3):172-182. doi: 10.1016/j.jphs.2020.07.014. [PMID: 32811746]
Fang Dou, Yi Ding, Cheng Wang, Jialin Duan, Wenjun Wang, Hang Xu, Xian Zhao, Jingwen Wang, Aidong Wen. Chrysophanol ameliorates renal interstitial fibrosis by inhibiting the TGF-β/Smad signaling pathway. Biochemical pharmacology. 2020 10; 180(?):114079. doi: 10.1016/j.bcp.2020.114079. [PMID: 32511988]
Danting Li, Bo Lv, Di Wang, Doudou Xu, Siyuan Qin, Ying Zhang, Jie Chen, Wei Zhang, Zunjian Zhang, Fengguo Xu. Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Jul; 72(?):153236. doi: 10.1016/j.phymed.2020.153236. [PMID: 32464544]
Yuanyuan Liu, Chuanqian Liu, Xueting Zhang, Zhenzhen Liu, Xipeng Yan. Chrysophanol protects PC12 cells against oxygen glucose deprivation-evoked injury by up-regulating miR-216a. Cell cycle (Georgetown, Tex.). 2020 06; 19(12):1433-1442. doi: 10.1080/15384101.2020.1731655. [PMID: 32401588]
Xueying Liu, Zehong Yang, Huixuan Li, Wen Luo, Wentao Duan, Junmei Zhang, Zhangzhi Zhu, Min Liu, Saimei Li, Xiaoyi Xin, Haoxiang Wu, Shaoxiang Xian, Meijing Liu, Changhui Liu, Chuangpeng Shen. Chrysophanol Alleviates Metabolic Syndrome by Activating the SIRT6/AMPK Signaling Pathway in Brown Adipocytes. Oxidative medicine and cellular longevity. 2020; 2020(?):7374086. doi: 10.1155/2020/7374086. [PMID: 33274005]
Chuan Guo, Yarong Wang, Yuanlin Piao, Xiangrong Rao, Dehai Yin. Chrysophanol Inhibits the Progression of Diabetic Nephropathy via Inactivation of TGF-β Pathway. Drug design, development and therapy. 2020; 14(?):4951-4962. doi: 10.2147/dddt.s274191. [PMID: 33235436]
Ya-Jun Bai, Yan-Bin Du, Xin-Zhu Yuan, Ning Yuan, Jiang Pu, Quan-Jun Zhang. [Regulation of Chrysophanol-mediated TLR4/NF-κB Pathway on Renal Injury and Immune Response in IgA Nephropathy Rats]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2019 Dec; 50(6):840-846. doi: . [PMID: 31880115]
Mohammad K Parvez, Mohammed S Al-Dosari, Perwez Alam, MdTabish Rehman, Mohammed F Alajmi, Ali S Alqahtani. The anti-hepatitis B virus therapeutic potential of anthraquinones derived from Aloe vera. Phytotherapy research : PTR. 2019 Nov; 33(11):2960-2970. doi: 10.1002/ptr.6471. [PMID: 31410907]
Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
Noha Fathalla, Mokhtar Bishr, Abdel Nasser Singab, Osama Salama. GC-MS and LC-MS Identification of the Phenolic Compounds Present in the ethyl Acetate Fraction Obtained from Senna tora, L. Roxb. seeds. Natural product research. 2019 Oct; 33(19):2878-2881. doi: 10.1080/14786419.2018.1508138. [PMID: 30445876]
Long Xie, Hailong Tang, Jiawen Song, Jiaying Long, Linlin Zhang, Xiaofang Li. Chrysophanol: a review of its pharmacology, toxicity and pharmacokinetics. The Journal of pharmacy and pharmacology. 2019 Oct; 71(10):1475-1487. doi: 10.1111/jphp.13143. [PMID: 31373015]
Bing Yang, Li Xie, Siying Peng, Kanping Sun, Junjie Jin, Yanping Zhen, Kunming Qin, Baochang Cai. Nine components pharmacokinetic study of rat plasma after oral administration raw and prepared Semen Cassiae in normal and acute liver injury rats. Journal of separation science. 2019 Jul; 42(14):2341-2350. doi: 10.1002/jssc.201900007. [PMID: 31037812]
Hyuk Chul Kwon, Tae Yang Kim, Chun Mong Lee, Kwang Sik Lee, Kun Kook Lee. Active compound chrysophanol of Cassia tora seeds suppresses heat-induced lipogenesis via inactivation of JNK/p38 MAPK signaling in human sebocytes. Lipids in health and disease. 2019 Jun; 18(1):135. doi: 10.1186/s12944-019-1072-x. [PMID: 31174532]
Rong-Rong Li, Xue-Fang Liu, Su-Xiang Feng, Sheng-Nan Shu, Pei-Yang Wang, Na Zhang, Jian-Sheng Li, Ling-Bo Qu. Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia. Molecules (Basel, Switzerland). 2019 May; 24(10):. doi: 10.3390/molecules24101898. [PMID: 31108858]
Hee-Yun Kim, Hyunwoo Jee, Jun-Ho Yeom, Hyun-Ja Jeong, Hyung-Min Kim. The ameliorative effect of AST2017-01 in an ovalbumin-induced allergic rhinitis animal model. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2019 May; 68(5):387-395. doi: 10.1007/s00011-019-01226-y. [PMID: 30874868]
Hui-Jun Gou, Ying Yang, Jie Ren, Jun Lu, Yuan Zheng, Ting Li. [Research on period of validity of emodin standard solution and chrysophanol standard solution]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2018 Dec; 43(24):4892-4899. doi: 10.19540/j.cnki.cjcmm.2018.0129. [PMID: 30717536]
Whasun Lim, Yikyung An, Changwon Yang, Fuller W Bazer, Gwonhwa Song. Chrysophanol induces cell death and inhibits invasiveness via mitochondrial calcium overload in ovarian cancer cells. Journal of cellular biochemistry. 2018 12; 119(12):10216-10227. doi: 10.1002/jcb.27363. [PMID: 30129050]
Anzhen Chen, Lei Sun, Hang Yuan, Aiying Wu, Jingguang Lu, Shuangcheng Ma. Simultaneous qualitative and quantitative analysis of 11 active compounds in rhubarb using two reference substances by UHPLC. Journal of separation science. 2018 Oct; 41(19):3686-3696. doi: 10.1002/jssc.201800479. [PMID: 30059192]
Ki Sun Kwon, Ju Hee Lee, Kyung Su So, Byung Kyu Park, Hyun Lim, Jae Sue Choi, Hyun Pyo Kim. Aurantio-obtusin, an anthraquinone from cassiae semen, ameliorates lung inflammatory responses. Phytotherapy research : PTR. 2018 Aug; 32(8):1537-1545. doi: 10.1002/ptr.6082. [PMID: 29675883]
Ying Sun, Xin Xin, Kehan Zhang, Tiantian Cui, Ying Peng, Jiang Zheng. Cytochrome P450 mediated metabolic activation of chrysophanol. Chemico-biological interactions. 2018 Jun; 289(?):57-67. doi: 10.1016/j.cbi.2018.04.015. [PMID: 29698620]
Ulrich Hildebrandt, Alexander Marsell, Markus Riederer. Direct Effects of Physcion, Chrysophanol, Emodin, and Pachybasin on Germination and Appressorium Formation of the Barley ( Hordeum vulgare L.) Powdery Mildew Fungus Blumeria graminis f. sp. hordei (DC.) Speer. Journal of agricultural and food chemistry. 2018 Apr; 66(13):3393-3401. doi: 10.1021/acs.jafc.7b05977. [PMID: 29554805]
Jie Zhang, Hua Kang, Lifang Wang, Xiaoyan Zhao. Chrysophanol ameliorates high-fat diet-induced obesity and inflammation in neonatal rats. Die Pharmazie. 2018 04; 73(4):228-233. doi: 10.1691/ph.2018.7980. [PMID: 29609691]
Xu Chu, Shuhu Zhou, Ran Sun, Lin Wang, Chunye Xing, Ruqing Liang, Qingxia Kong. Chrysophanol Relieves Cognition Deficits and Neuronal Loss Through Inhibition of Inflammation in Diabetic Mice. Neurochemical research. 2018 Apr; 43(4):972-983. doi: 10.1007/s11064-018-2503-1. [PMID: 29497904]
Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu. Chrysophanol inhibits proliferation and induces apoptosis through NF-κB/cyclin D1 and NF-κB/Bcl-2 signaling cascade in breast cancer cell lines. Molecular medicine reports. 2018 03; 17(3):4376-4382. doi: 10.3892/mmr.2018.8443. [PMID: 29344652]
Renato Sonchini Gonçalves, Expedito Leite Silva, Noboru Hioka, Celso Vataru Nakamura, Marcos Luciano Bruschi, Wilker Caetano. An optimized protocol for anthraquinones isolation from Rhamnus frangula L. Natural product research. 2018 Feb; 32(3):366-369. doi: 10.1080/14786419.2017.1356836. [PMID: 28745519]
Xue Wang, Lifeng Han, Gentao Li, Wei Peng, Xiumei Gao, Curtis D Klaassen, Guanwei Fan, Youcai Zhang. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity. Toxicological sciences : an official journal of the Society of Toxicology. 2018 02; 161(2):321-334. doi: 10.1093/toxsci/kfx216. [PMID: 29045746]
Li Kang, Luqin Si, Jing Rao, Dan Li, Ya Wu, Sanlan Wu, Minghui Wu, Sijie He, Wenwen Zhu, Yang Wu, Jiaqiang Xu, Gao Li, Jiangeng Huang. Polygoni Multiflori Radix derived anthraquinones alter bile acid disposition in sandwich-cultured rat hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA. 2017 Apr; 40(?):313-323. doi: 10.1016/j.tiv.2017.01.022. [PMID: 28161596]
Yu-Mei Zhang, Hong-Yu Ren, Xian-Lin Zhao, Juan Li, Jun-Yi Li, Fu-Sheng Wu, Hang Su, Wen-Fu Tang. Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis. World journal of gastroenterology. 2017 Feb; 23(8):1367-1374. doi: 10.3748/wjg.v23.i8.1367. [PMID: 28293083]
Kan Chen, Chang-Qian Wang, Yu-Qi Fan, Zhi-Hua Han, Yue Wang, Lin Gao, Hua-Su Zeng. [Lipid-lowering effect of seven traditional Chinese medicine monomers in zebrafish system]. Sheng li xue bao : [Acta physiologica Sinica]. 2017 Feb; 69(1):55-60. doi: . [PMID: 28217808]
Jianhui Cheng, Lingyu Wang, Weifen Liu, David D Y Chen. Quantitative Nonaqueous Capillary Electrophoresis-Mass Spectrometry Method for Determining Active Ingredients in Plant Extracts. Analytical chemistry. 2017 02; 89(3):1411-1415. doi: 10.1021/acs.analchem.6b04944. [PMID: 28208307]
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