Lecanoricacid (BioDeep_00000003760)

   

PANOMIX_OTCML-2023


代谢物信息卡片


4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid

化学式: C16H14O7 (318.0739494)
中文名称: 紅粉苔酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 3.48%

分子结构信息

SMILES: C1(C(O)=CC(O)=CC=1C)C(=O)OC1C=C(C(C(=O)O)=C(C)C=1)O
InChI: InChI=1S/C16H14O7/c1-7-3-9(17)5-11(18)14(7)16(22)23-10-4-8(2)13(15(20)21)12(19)6-10/h3-6,17-19H,1-2H3,(H,20,21)

描述信息

D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase[1].

同义名列表

5 个代谢物同义名

Lecanoric acid; Lecanoricacid; 4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid; Orsellinate depside; NSC 249981



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

38 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tatapudi Kiran Kumar, Bandi Siva, Basani Kiranmai, Vidya Jyothi Alli, Surender Singh Jadav, Araveeti Madhusudana Reddy, Joël Boustie, Françoise Le Devehat, Ashok Kumar Tiwari, Katragadda Suresh Babu. Salazinic Acid and Norlobaridone from the Lichen Hypotrachyna cirrhata: Antioxidant Activity, α-Glucosidase Inhibitory and Molecular Docking Studies. Molecules (Basel, Switzerland). 2023 Nov; 28(23):. doi: 10.3390/molecules28237840. [PMID: 38067568]
  • Mohsen Vaez, Seyed Javad Davarpanah. New Insights into the Biological Activity of Lichens: Bioavailable Secondary Metabolites of Umbilicaria decussata as Potential Anticoagulants. Chemistry & biodiversity. 2021 May; 18(5):e2100080. doi: 10.1002/cbdv.202100080. [PMID: 33773025]
  • Friederike Lünne, Eva-Maria Niehaus, Sarah Lipinski, Jonas Kunigkeit, Svetlana A Kalinina, Hans-Ulrich Humpf. Identification of the polyketide synthase PKS7 responsible for the production of lecanoric acid and ethyl lecanorate in Claviceps purpurea. Fungal genetics and biology : FG & B. 2020 12; 145(?):103481. doi: 10.1016/j.fgb.2020.103481. [PMID: 33130255]
  • Richard Staples, Robert L LaDuca, Ludmila V Roze, Maris Laivenieks, John E Linz, Randolph Beaudry, Alan Fryday, Anthony L Schilmiller, Anna V Koptina, Benjamin Smith, Frances Trail. Structure and Chemical Analysis of Major Specialized Metabolites Produced by the Lichen Evernia prunastri. Chemistry & biodiversity. 2020 Jan; 17(1):e1900465. doi: 10.1002/cbdv.201900465. [PMID: 31701649]
  • Michal Goga, Sebastian J Antreich, Martin Bačkor, Wolfram Weckwerth, Ingeborg Lang. Lichen secondary metabolites affect growth of Physcomitrella patens by allelopathy. Protoplasma. 2017 May; 254(3):1307-1315. doi: 10.1007/s00709-016-1022-7. [PMID: 27645140]
  • An-Hua Wei, Dao-Nian Zhou, Jin-Lan Ruan, Ya-Ling Cai, Chao-Mei Xiong, Ming-Xing Li. Characterisation of phenols and antioxidant and hypolipidaemic activities of Lethariella cladonioides. Journal of the science of food and agriculture. 2012 Jan; 92(2):373-9. doi: 10.1002/jsfa.4601. [PMID: 21918996]
  • Branislav R Ranković, Marijana M Kosanić, Tatjana P Stanojković. Antioxidant, antimicrobial and anticancer activity of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis. BMC complementary and alternative medicine. 2011 Oct; 11(?):97. doi: 10.1186/1472-6882-11-97. [PMID: 22013953]
  • Christopher J Johnson, James P Bennett, Steven M Biro, Juan Camilo Duque-Velasquez, Cynthia M Rodriguez, Richard A Bessen, Tonie E Rocke. Degradation of the disease-associated prion protein by a serine protease from lichens. PloS one. 2011 May; 6(5):e19836. doi: 10.1371/journal.pone.0019836. [PMID: 21589935]
  • Heng Luo, Yoshikazu Yamamoto, Yanpeng Liu, Jae Sung Jung, Hyung-Yeel Kahng, Young Jin Koh, Jae-Seoun Hur. The In vitro antioxidant properties of chinese highland lichens. Journal of microbiology and biotechnology. 2010 Nov; 20(11):1524-8. doi: 10.4014/jmb.1003.03029. [PMID: 21124057]
  • Danielle Bogo, Maria Fatima Cepa de Matos, Neli Kika Honda, Elenir Curi Pontes, Patricia Midori Oguma, Evelyn Cristina Silva da Santos, João Ernesto de Carvalho, Auro Nomizo. In vitro antitumour activity of orsellinates. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2010 Jan; 65(1-2):43-8. doi: 10.1515/znc-2010-1-208. [PMID: 20355320]
  • Changon Seo, Yun-Hyeok Choi, Jong Seog Ahn, Joung Han Yim, Hong Kum Lee, Hyuncheol Oh. PTP1B inhibitory effects of tridepside and related metabolites isolated from the Antarctic lichen Umbilicaria antarctica. Journal of enzyme inhibition and medicinal chemistry. 2009 Oct; 24(5):1133-7. doi: 10.1080/14756360802667811. [PMID: 19619069]
  • Iracilda Z Carlos, Marcela B Quilles, Camila B A Carli, Danielle C G Maia, Fernanda P Benzatti, Thiago I B Lopes, Aline S Gianini, Rosenei L Brum, Wagner Vilegas, Lourdes C dos Santos, Neli K Honda. Lichen metabolites modulate hydrogen peroxide and nitric oxide in mouse macrophages. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2009 Sep; 64(9-10):664-72. doi: 10.1515/znc-2009-9-1010. [PMID: 19957434]
  • C Qiu, Y Ding. [Studies on chemical constituents of Umbilicaria esculenta (Miyoshi) minks]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2001 Sep; 26(9):608-10. doi: . [PMID: 12776427]