Salidroside (BioDeep_00000000374)

 

Secondary id: BioDeep_00000183132, BioDeep_00000862209

natural product PANOMIX_OTCML-2023


代谢物信息卡片


(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol

化学式: C14H20O7 (300.1209)
中文名称: 红景天甙, 毛柳甙, 红景天苷
谱图信息: 最多检出来源 Viridiplantae(plant) 21.49%

分子结构信息

SMILES: C1=CC(=CC=C1CCOC2C(C(C(C(O2)CO)O)O)O)O
InChI: InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

描述信息

Salidroside is a glycoside.
Salidroside is a natural product found in Plantago australis, Plantago coronopus, and other organisms with data available.
See also: Sedum roseum root (part of); Rhodiola crenulata root (part of).
Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.

同义名列表

43 个代谢物同义名

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-3,4,5-triol; (2R,3R,4S,5S,6R)-2-[2-(4-hydroxyphenyl)ethoxy]-6-methylol-tetrahydropyran-3,4,5-triol; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol; 2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol; Salidroside, United States Pharmacopeia (USP) Reference Standard; Salidroside, primary pharmaceutical reference standard; .BETA.-D-GLUCOPYRANOSIDE, 2-(4-HYDROXYPHENYL)ETHYL-; 2-(4-HYDROXYPHENYL)ETHYL-.BETA.-D-GLUCOPYRANOSIDE; SALIDROSIDE (CONSTITUENT OF RHODIOLA ROSEA) [DSC]; beta-D-glucopyranoside, 2-(4-hydroxyphenyl)ethyl-; beta-D-Glucopyranoside, 2-(4-hydroxyphenyl)ethyl; 2-(4-Hydroxyphenyl)ethyl beta-D-glucopyranoside; 2-(4-hydroxyphenyl)ethyl-beta-d-glucopyranoside; p-Hydroxyphenethyl alcohol 1-O-beta-D-glucoside; 2-(4-Hydroxyphenyl)ethyl ?-D-glucopyranoside; SALIDROSIDE (CONSTITUENT OF RHODIOLA ROSEA); TYROSOL .ALPHA.-(.BETA.-D-GLUCOPYRANOSIDE); 4-hydroxyphenyl-2-ethylglucopyranoside; TYROSOL alpha-(beta-D-GLUCOPYRANOSIDE); (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-; Glucopyranoside, p-hydroxyphenethyl; (4-hydroxyphenethoxy)tetrahydro-2H-; Salidroside, analytical standard; Salidroside, >=95\\% (LC/MS-ELSD); 8-O-b-D-glucoside of tyrosol; salidroside (rhodioloside); SALIDROSIDE [USP-RS]; SALIDROSIDE (USP-RS); Tyrosol glucoside; pyran-3,4,5-triol; salidroside, (-)-; Salidroside,(S); Tox21_113565_1; MEGxp0_000478; sallidroside; Tox21_113565; ACon1_000366; rhodioloside; Salidroside; rhodosin; Hydroxyphenylethanol + Pen; Salidroside



数据库引用编号

44 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

5 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(3)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

358 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 ANG, CASP1, GSDMD, IL18, MAP2, NOS2, NOS3, PPARG, PRKAA2, PTGS2, SIRT1, STAT3, TXNIP, VEGFA
Peripheral membrane protein 1 PTGS2
Endoplasmic reticulum membrane 2 HMOX1, PTGS2
Mitochondrion membrane 1 GSDMD
Nucleus 10 ANG, HMOX1, NOS2, NOS3, PPARG, PPARGC1A, PRKAA2, SIRT1, STAT3, VEGFA
cytosol 14 ANG, CASP1, GSDMD, HMOX1, IL18, MAP2, NOS2, NOS3, PPARG, PPARGC1A, PRKAA2, SIRT1, STAT3, TXNIP
dendrite 2 MAP2, PRKAA2
mitochondrial membrane 1 GSDMD
nucleoplasm 9 GSDMD, HMOX1, NOS2, NOS3, PPARG, PPARGC1A, PRKAA2, SIRT1, STAT3
RNA polymerase II transcription regulator complex 2 PPARG, STAT3
Cell membrane 3 CASP1, CD8A, GSDMD
Cytoplasmic side 1 HMOX1
Multi-pass membrane protein 1 GSDMD
cell surface 1 VEGFA
dendritic shaft 1 MAP2
Golgi apparatus 3 NOS3, PRKAA2, VEGFA
Golgi membrane 2 INS, NOS3
growth cone 1 ANG
neuronal cell body 3 ANG, MAP2, PRKAA2
Cytoplasm, cytosol 2 IL18, NOS2
plasma membrane 6 CASP1, CD8A, GSDMD, NOS2, NOS3, STAT3
Membrane 4 GSDMD, HMOX1, PRKAA2, VEGFA
axon 1 PRKAA2
caveola 2 NOS3, PTGS2
endoplasmic reticulum 3 HMOX1, PTGS2, VEGFA
extracellular space 8 ANG, GSDMD, HMOX1, IL17A, IL18, IL5, INS, VEGFA
perinuclear region of cytoplasm 4 HMOX1, NOS2, NOS3, PPARG
adherens junction 1 VEGFA
mitochondrion 1 SIRT1
protein-containing complex 2 CASP1, PTGS2
intracellular membrane-bounded organelle 1 PPARG
Microsome membrane 1 PTGS2
chromatin silencing complex 1 SIRT1
Single-pass type I membrane protein 1 CD8A
Secreted 7 ANG, GSDMD, IL17A, IL18, IL5, INS, VEGFA
extracellular region 8 ANG, CD8A, GSDMD, IL17A, IL18, IL5, INS, VEGFA
mitochondrial outer membrane 1 HMOX1
[Isoform 2]: Secreted 1 CD8A
transcription regulator complex 1 STAT3
external side of plasma membrane 2 CD8A, IL17A
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 ANG
nucleolus 3 ANG, CASP1, SIRT1
Cytoplasm, P-body 2 NOS2, NOS3
P-body 2 NOS2, NOS3
Cytoplasm, perinuclear region 1 NOS2
heterochromatin 1 SIRT1
Cytoplasm, cytoskeleton 1 MAP2
microtubule 2 CASP1, MAP2
extracellular matrix 1 VEGFA
Peroxisome 1 NOS2
basement membrane 1 ANG
peroxisomal matrix 1 NOS2
Nucleus, PML body 2 PPARGC1A, SIRT1
PML body 2 PPARGC1A, SIRT1
secretory granule 1 VEGFA
nuclear speck 1 PRKAA2
Inflammasome 1 GSDMD
NLRP3 inflammasome complex 2 CASP1, GSDMD
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 2 PTGS2, SIRT1
nuclear outer membrane 1 PTGS2
dendrite cytoplasm 1 MAP2
receptor complex 2 CD8A, PPARG
neuron projection 2 MAP2, PTGS2
chromatin 4 PPARG, PPARGC1A, SIRT1, STAT3
microtubule associated complex 1 MAP2
Chromosome 1 ANG
cytoskeleton 1 NOS3
Nucleus, nucleolus 1 ANG
fibrillar center 1 SIRT1
nuclear envelope 1 SIRT1
Endomembrane system 1 GSDMD
endosome lumen 1 INS
axon initial segment 1 MAP2
Cell projection, dendrite 1 MAP2
Cytoplasm, Stress granule 2 ANG, NOS3
cytoplasmic stress granule 3 ANG, NOS3, PRKAA2
euchromatin 1 SIRT1
dendritic growth cone 1 MAP2
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 1 GSDMD
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, PTGS2
platelet alpha granule lumen 1 VEGFA
specific granule lumen 1 GSDMD
tertiary granule lumen 1 GSDMD
endocytic vesicle membrane 1 NOS3
proximal neuron projection 1 MAP2
endocytic vesicle 1 ANG
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
AIM2 inflammasome complex 1 CASP1
axon hillock 1 MAP2
[Isoform 1]: Nucleus 1 PPARGC1A
basal dendrite 1 MAP2
canonical inflammasome complex 1 CASP1
[Isoform 1]: Cell membrane 1 CD8A
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
nucleotide-activated protein kinase complex 1 PRKAA2
T cell receptor complex 1 CD8A
cortical cytoskeleton 1 NOS2
angiogenin-PRI complex 1 ANG
apical distal dendrite 1 MAP2
dendritic branch 1 MAP2
dendritic filopodium 1 MAP2
distal dendrite 1 MAP2
primary dendrite 1 MAP2
proximal dendrite 1 MAP2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
IPAF inflammasome complex 1 CASP1
NLRP1 inflammasome complex 1 CASP1
protease inhibitor complex 1 CASP1
[Gasdermin-D]: Cytoplasm, cytosol 1 GSDMD
[Gasdermin-D, N-terminal]: Cell membrane 1 GSDMD
[Gasdermin-D, N-terminal]: Cytoplasm, cytosol 1 GSDMD
[Gasdermin-D, p13]: Nucleus 1 GSDMD
[Gasdermin-D, C-terminal]: Cytoplasm, cytosol 1 GSDMD
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1
[Isoform B4]: Nucleus 1 PPARGC1A
[Isoform B4-8a]: Cytoplasm 1 PPARGC1A
[Isoform B5]: Nucleus 1 PPARGC1A
[Isoform 9]: Nucleus 1 PPARGC1A


文献列表

  • Zehui Li, Jiashan Li, Yuan Li, Li Guo, Panyu Xu, Hanqian Du, Na Lin, Ying Xu. The role of Cistanches Herba and its ingredients in improving reproductive outcomes: A comprehensive review. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155681. doi: 10.1016/j.phymed.2024.155681. [PMID: 38718638]
  • Bin Yang, Ying Xu, Jingzhi Yu, Qihao Wang, Qigui Fan, Xiaoyu Zhao, Yang Qiao, Zeyu Zhang, Qing Zhou, Dong Yin, Ming He, Huan He. Salidroside pretreatment alleviates ferroptosis induced by myocardial ischemia/reperfusion through mitochondrial superoxide-dependent AMPKα2 activation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155365. doi: 10.1016/j.phymed.2024.155365. [PMID: 38552436]
  • Ya Hou, Fuhan Fan, Na Xie, Yi Zhang, Xiaobo Wang, Xianli Meng. Rhodiola crenulata alleviates hypobaric hypoxia-induced brain injury by maintaining BBB integrity and balancing energy metabolism dysfunction. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155529. doi: 10.1016/j.phymed.2024.155529. [PMID: 38503156]
  • Lirong Huang, Jiaxin Xu, Kun Jia, Yulin Wu, Wei Yuan, Zhipeng Liao, Bo Cheng, Qiang Luo, Guiyou Tian, Huiqiang Lu. Butylparaben induced zebrafish (Danio rerio) kidney injury by down-regulating the PI3K-AKT pathway. Journal of hazardous materials. 2024 May; 470(?):134129. doi: 10.1016/j.jhazmat.2024.134129. [PMID: 38565019]
  • Suxin You, Zhouyun Ma, Pei Zhang, Wenwen Xu, Changsen Zhan, Nina Sang, Jiazhen Xu, Feiyun Wang, Jiange Zhang. Neuroprotective effects of the salidroside derivative SHPL-49 via the BDNF/TrkB/Gap43 pathway in rats with cerebral ischemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116460. doi: 10.1016/j.biopha.2024.116460. [PMID: 38520864]
  • Xianqi Zhang, Mengdi Zhang, Ziyan Zhang, Shengbo Zhou. Salidroside induces mitochondrial dysfunction and ferroptosis to inhibit melanoma progression through reactive oxygen species production. Experimental cell research. 2024 May; 438(1):114034. doi: 10.1016/j.yexcr.2024.114034. [PMID: 38588875]
  • Guosi Li, Wei Wang, Heng Guo, Shanyong Yi, Fang Wang, Shiping Huang, Nan Hu, Qilin Xu, Yongjun Zang, Bangxing Han, Xinjian Yin. Mutability landscape guided engineering of a promiscuous microbial glycosyltransferase for regioselective synthesis of salidroside and icariside D2. International journal of biological macromolecules. 2024 Apr; 263(Pt 1):130229. doi: 10.1016/j.ijbiomac.2024.130229. [PMID: 38378110]
  • Guosi Li, Qilin Xu, Nan Hu, Xinyang Liu, Yiqi Jiang, Hailong Xue, Yongjun Zang, Fucheng Zhu. Highly efficient biosynthesis of salidroside by a UDP-glucosyltransferase-catalyzed cascade reaction. Biotechnology letters. 2024 Jan; ?(?):. doi: 10.1007/s10529-023-03453-0. [PMID: 38184486]
  • Qiao Liu, Qingman Luo, Bin Zhong, Kecheng Tang, Xueling Chen, Shengqian Yang, Xiaohui Li. Salidroside attenuates myocardial remodeling in DOCA-salt-induced mice by inhibiting the endothelin 1 and PI3K/AKT/NFκB signaling pathways. European journal of pharmacology. 2024 Jan; 962(?):176236. doi: 10.1016/j.ejphar.2023.176236. [PMID: 38048979]
  • Dan-Qing Zhang, Xiao-Ying Liu, Lin-Feng Qiu, Zhao-Rui Liu, Ya-Peng Yang, Long Huang, Shi-Yu Wang, Jian-Qiang Zhang. Two chromosome-level genome assemblies of Rhodiola shed new light on genome evolution in rapid radiation and evolution of the biosynthetic pathway of salidroside. The Plant journal : for cell and molecular biology. 2024 Jan; 117(2):464-482. doi: 10.1111/tpj.16501. [PMID: 37872890]
  • Ting Zhu, Hui Liu, Shiman Gao, Ning Jiang, Shuai Chen, Weijie Xie. Effect of salidroside on neuroprotection and psychiatric sequelae during the COVID-19 pandemic: A review. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Jan; 170(?):115999. doi: 10.1016/j.biopha.2023.115999. [PMID: 38091637]
  • Liu Shuyuan, Chen Haoyu. Mechanism of Nardostachyos Radix et Rhizoma-Salidroside in the treatment of premature ventricular beats based on network pharmacology and molecular docking. Scientific reports. 2023 11; 13(1):20741. doi: 10.1038/s41598-023-48277-0. [PMID: 38007574]
  • Bing Jiang, Yangyang Cui, Xinxin Ma, Yanmei Zhang, Xin Feng, Tao Yang, Longfei Feng, Wenjing Guo, Yangyang Li, Tao Wang, Huan Guo, Haining Li, Ying Duan, Haixiang Su. Crosstalk between autophagy inhibitor and salidroside-induced apoptosis: A novel strategy for autophagy-based treatment of hepatocellular cancer. International immunopharmacology. 2023 Nov; 124(Pt B):111040. doi: 10.1016/j.intimp.2023.111040. [PMID: 37839277]
  • Mu-Han Chen, Xin-Ze Liu, Xiu-Wu Qu, Rui-Bo Guo, Lu Zhang, Liang Kong, Yang Yu, Yang Liu, Juan Zang, Xiu-Ying Li, Xue-Tao Li. ApoE-modified liposomes encapsulating resveratrol and salidroside alleviate manifestations of Alzheimer's disease in APP/PS-1 mice. Drug development and industrial pharmacy. 2023 Sep; ?(?):1-13. doi: 10.1080/03639045.2023.2252062. [PMID: 37649422]
  • Feng Chen, Yi Hong Chai, Fa Zhang, Yong Qiang Liu, Yan Zhang, Ya Jing Shi, Jian Ming Zhang, Yu-Fang Leng. Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of salidroside on intestine ischemia reperfusion. Bioscience reports. 2023 Aug; ?(?):. doi: 10.1042/bsr20230539. [PMID: 37530723]
  • Edward J Calabrese, Gaurav Dhawan, Rachna Kapoor, Evgenios Agathokleous, Vittorio Calabrese. Rhodiola rosea and salidroside commonly induce hormesis, with particular focus on longevity and neuroprotection. Chemico-biological interactions. 2023 Aug; 380(?):110540. doi: 10.1016/j.cbi.2023.110540. [PMID: 37169278]
  • Zexin Wen, Tong Liu, Yanli Zhang, Qiujuan Yue, Hang Meng, Yijie He, Yi Yang, Minghao Li, Jianwen Zheng, Wei Lin. Salidroside regulates tumor microenvironment of non-small cell lung cancer via Hsp70/Stub1/Foxp3 pathway in Tregs. BMC cancer. 2023 Aug; 23(1):717. doi: 10.1186/s12885-023-11036-5. [PMID: 37528345]
  • Jie Ma, Yujie Li, Xiaodi Ji, Anqi Wang, Yue Lan, Lihong Ma. Integrating network pharmacology and experimental verification to explore the mechanisms of salidroside against myocardial fibrosis. Biochemical and biophysical research communications. 2023 Aug; 677(?):38-44. doi: 10.1016/j.bbrc.2023.07.059. [PMID: 37544102]
  • Xue-Hua Wang, Zhong-Fu Zuo, Lu Meng, Qi Yang, Pan Lv, Li-Pan Zhao, Xiao-Bai Wang, Yu-Fei Wang, Ying Huang, Cong Fu, Wen-Qiang Liu, Xue-Zheng Liu, De-Yu Zheng. Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway. Psychopharmacology. 2023 Jul; ?(?):. doi: 10.1007/s00213-023-06373-z. [PMID: 37490132]
  • Ru-Han Liu, Teng-Fei Ma, Qin Yang, Wen-Chang Xiao, Lu Yin, Miao Yin, Jin-Song Zhang, Chi-Hua Wang. Salidroside suppresses proliferation and migration in prostate cancer via the PI3K/AKT pathway. Cancer biomarkers : section A of Disease markers. 2023 Jul; ?(?):. doi: 10.3233/cbm-220454. [PMID: 37545219]
  • Pei Zhang, Jiazhen Xu, Qianfei Cui, Guoqiang Lin, Feiyun Wang, Xinyue Ding, Suxin You, Nina Sang, Junchao Tan, Wenwen Xu, Changsen Zhan, Yuying Zhu, Jiange Zhang. Multi-pathway neuroprotective effects of a novel salidroside derivative SHPL-49 against acute cerebral ischemic injury. European journal of pharmacology. 2023 Jun; 949(?):175716. doi: 10.1016/j.ejphar.2023.175716. [PMID: 37059375]
  • Lin Tao, Zhi-Fang Liang, Liu Miao, Yu-Jie Guo, Ye Li, Yan-Li Liu, Dong-Ming Fang, Zhi-Jie Yang. Mechanism of salidroside against coronary artery disease by network pharmacology analysis. BMC complementary medicine and therapies. 2023 Jun; 23(1):194. doi: 10.1186/s12906-023-04027-3. [PMID: 37308900]
  • Yushiro Fuji, Kai Uchida, Tomoyoshi Akashi, Takashi Ohtsuki, Hiroshi Matsufuji, Masami Yokota Hirai. Molecular Identification of UDP-Sugar Dependent Glycosyltransferase and Acyltransferase Involved in the Phenylethanoid Glycoside Biosynthesis Induced by Methyl Jasmonate in Sesamum indicum L. Plant & cell physiology. 2023 May; ?(?):. doi: 10.1093/pcp/pcad053. [PMID: 37233612]
  • Zhengming Xu, Shuang Liu, Huining Lai, Lijun You, Zhengang Zhao. Green-Efficient Enzymatic Synthesis and Characterization of Liposoluble 6'/6″-O-Lauryl Phenolic Glycosides with Enhanced Intestinal Permeability. Journal of agricultural and food chemistry. 2023 May; 71(20):7689-7702. doi: 10.1021/acs.jafc.3c00527. [PMID: 37167604]
  • Shihua Shi, Demei Huang, Yongcan Wu, Caixia Pei, Yilan Wang, Zherui Shen, Sijing Zhao, Nan Jia, Xiaomin Wang, Bonan Chen, Jie Pan, Fei Wang, Zhenxing Wang. Salidroside pretreatment alleviates PM2.5 caused lung injury via inhibition of apoptosis and pyroptosis through regulating NLRP3 Inflammasome. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 May; 177(?):113858. doi: 10.1016/j.fct.2023.113858. [PMID: 37236293]
  • Jiuxi Liu, Jiapei Cai, Peng Fan, Xue Dong, Naisheng Zhang, Jiandong Tai, Yongguo Cao. Salidroside protects mice from high-fat diet-induced obesity by modulating the gut microbiota. International immunopharmacology. 2023 May; 120(?):110278. doi: 10.1016/j.intimp.2023.110278. [PMID: 37192552]
  • Hongkang Zhu, Fanglin Shen, Xiaochen Wang, Yuliang Cheng, Yahui Guo, He Qian, Yu Liu. Reshaped Gut Microbial Composition and Functions Associated with the Antifatigue Effect of Salidroside in Exercise Mice. Molecular nutrition & food research. 2023 Apr; ?(?):e2300015. doi: 10.1002/mnfr.202300015. [PMID: 37082899]
  • Lingling Xiao, Liang Li, Jingcong Huang, Yuting Luan, Jiaying Pan, Yun Gai, Zhenyu Xu. Salidroside attenuates lipopolysaccharide-induced neuroinflammation and cognitive impairment in septic encephalopathy mice. International immunopharmacology. 2023 Apr; 117(?):109975. doi: 10.1016/j.intimp.2023.109975. [PMID: 36948107]
  • Hanna Nikolaichuk, Irena M Choma, Gertrud E Morlock. Effect-Directed Profiling of Akebia quinata and Clitoria ternatea via High-Performance Thin-Layer Chromatography, Planar Assays and High-Resolution Mass Spectrometry. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28072893. [PMID: 37049655]
  • Yihan Yang, Daoyi Xi, Yanan Wu, Tao Liu. Complete Biosynthesis of Phenylethanoid Glycoside Verbascoside. Plant communications. 2023 Mar; ?(?):100592. doi: 10.1016/j.xplc.2023.100592. [PMID: 36935606]
  • Sixia Yang, Linshuang Wang, Yi Zeng, Yong Wang, Tingting Pei, Zeping Xie, Qiaowu Xiong, Hui Wei, Wenxu Li, Jiaqi Li, Qian Su, Dongfeng Wei, Weidong Cheng. Salidroside alleviates cognitive impairment by inhibiting ferroptosis via activation of the Nrf2/GPX4 axis in SAMP8 mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Mar; 114(?):154762. doi: 10.1016/j.phymed.2023.154762. [PMID: 36965372]
  • Bing Jiang, Longfei Feng, Tao Yang, Wenjing Guo, Yangyang Li, Tao Wang, Chengguang Liu, Haixiang Su. Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy. Molecular medicine reports. 2023 Feb; 27(2):. doi: 10.3892/mmr.2022.12924. [PMID: 36579660]
  • Yun Wang, Zhe Chen, Jing Luo, Jing Zhang, A-Ming Sang, Zhen-Shun Cheng, Xin-Yi Li. Salidroside postconditioning attenuates ferroptosis-mediated lung ischemia-reperfusion injury by activating the Nrf2/SLC7A11 signaling axis. International immunopharmacology. 2023 Feb; 115(?):109731. doi: 10.1016/j.intimp.2023.109731. [PMID: 36907990]
  • Yihong Chai, Feng Chen, Zijian Li, Panpan Yang, Qi Zhou, Wenling Liu, Yaming Xi. Mechanism of salidroside in the treatment of chronic myeloid leukemia based on the network pharmacology and molecular docking. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2023 Feb; 25(2):384-395. doi: 10.1007/s12094-022-02990-w. [PMID: 36369630]
  • Kun Wang, Li Wang, Guojing Zhao, Yong Liu, Fengchan Wang, Huan Song, Yin Sun, Zhaoshan Zhou, Xuechao Lu, Haibo Hu, Huantian Cui. Mechanistic study of salidroside on ovalbumin-induced asthmatic model mice based on untargeted metabolomics analysis. Food & function. 2023 Jan; 14(1):413-426. doi: 10.1039/d2fo02225g. [PMID: 36515134]
  • Jun Zhou, Shan Yan, Xu Guo, Yanguo Gao, Shiqi Chen, Xiaohan Li, Yonghong Zhang, Qibin Wang, Tao Zheng, Li Chen. Salidroside protects pancreatic β-cells against pyroptosis by regulating the NLRP3/GSDMD pathway in diabetic conditions. International immunopharmacology. 2023 Jan; 114(?):109543. doi: 10.1016/j.intimp.2022.109543. [PMID: 36508922]
  • Jiaying Pan, Jie Zhu, Liang Li, Tao Zhang, Zhenyu Xu. Salidroside attenuates LPS-induced kidney injury through activation of SIRT1/Nrf2 pathway. Human & experimental toxicology. 2023 Jan; 42(?):9603271231169520. doi: 10.1177/09603271231169520. [PMID: 37078094]
  • Ya Hou, Yating Zhang, Shengnan Jiang, Na Xie, Yi Zhang, Xianli Meng, Xiaobo Wang. Salidroside intensifies mitochondrial function of CoCl2-damaged HT22 cells by stimulating PI3K-AKT-MAPK signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jan; 109(?):154568. doi: 10.1016/j.phymed.2022.154568. [PMID: 36610162]
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