Cirsiliol (BioDeep_00000270028)

 

Secondary id: BioDeep_00000007762

PANOMIX_OTCML-2023


代谢物信息卡片


6-Hydroxyluteolin-6,7-dimethyl ether; 6-Methoxyluteolin 7-methyl ether; Crisiliol

化学式: C17H14O7 (330.0739494)
中文名称: 条叶蓟素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(OC)=CC2OC(C3C=CC(O)=C(O)C=3)=CC(=O)C=2C(O)=C1OC
InChI: InChI=1S/C17H14O7/c1-22-14-7-13-15(16(21)17(14)23-2)11(20)6-12(24-13)8-3-4-9(18)10(19)5-8/h3-7,18-19,21H,1-2H3

描述信息

Cirsiliol is a dimethoxyflavone that is flavone substituted by methoxy groups at positions 6 and 7 and hydroxy groups at positions 5, 3 and 4 respectively. It has a role as a plant metabolite. It is a trihydroxyflavone and a dimethoxyflavone. It is functionally related to a flavone.
Cirsiliol is a natural product found in Teucrium montanum, Thymus herba-barona, and other organisms with data available.
A dimethoxyflavone that is flavone substituted by methoxy groups at positions 6 and 7 and hydroxy groups at positions 5, 3 and 4 respectively.
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.

同义名列表

22 个代谢物同义名

6-Hydroxyluteolin-6,7-dimethyl ether; 6-Methoxyluteolin 7-methyl ether; Crisiliol; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one; 2-(3,4-Dihydroxy-phenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one; 3,4,5-trihydroxy-6,7-dimethoxy-flavone; 6,7-Dimethoxy-5,3,4-trihydroxyflavone; 5,3,4-trihydroxy-6,7-dimethoxyflavone; 3,4,5-trihydroxy-6,7-dimethoxyflavone; 5,3,4-Trihydroxy-6,7-dimethoxyflavone; 6,7-DIMETHOXY-3,4,5-TRIHYDROXYFLAVONE; 6-methoxyluteolin 7-methyl ether; UNII-8W4Y5JK3XE; 8W4Y5JK3XE; Cirsiliol; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4-chromenone; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-chromone; 34334-69-5; ST5331608; C10033



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

59 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Benedetta Fois, Angela Corona, Enzo Tramontano, Simona Distinto, Elias Maccioni, Rita Meleddu, Pierluigi Caboni, Costantino Floris, Filippo Cottiglia. Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function. Journal of enzyme inhibition and medicinal chemistry. 2021 Dec; 36(1):749-757. doi: 10.1080/14756366.2021.1887170. [PMID: 33715562]
  • Akram Taleghani, Seyed Ahmad Emami, Zahra Tayarani-Najaran. Artemisia: a promising plant for the treatment of cancer. Bioorganic & medicinal chemistry. 2020 01; 28(1):115180. doi: 10.1016/j.bmc.2019.115180. [PMID: 31784199]
  • Wael A Elmasri, Tianjiao Yang, Phat Tran, Mohamed-Elamir F Hegazy, Abdul N Hamood, Yehia Mechref, Paul W Paré. Teucrium polium phenylethanol and iridoid glycoside characterization and flavonoid inhibition of biofilm-forming Staphylococcus aureus. Journal of natural products. 2015 Jan; 78(1):2-9. doi: 10.1021/np5004092. [PMID: 25524452]
  • Peter Forgo, István Zupkó, Judit Molnár, Andrea Vasas, György Dombi, Judit Hohmann. Bioactivity-guided isolation of antiproliferative compounds from Centaurea jacea L. Fitoterapia. 2012 Jul; 83(5):921-5. doi: 10.1016/j.fitote.2012.04.006. [PMID: 22537643]
  • Jun Li, Frank R Fronczek, Daneel Ferreira, Charles L Burandt, Vincent Setola, Bryan L Roth, Jordan K Zjawiony. Bis-spirolabdane diterpenoids from Leonotis nepetaefolia. Journal of natural products. 2012 Apr; 75(4):728-34. doi: 10.1021/np3000156. [PMID: 22475308]
  • Shuangqing Wu, Qun Sun, Chunjun Chu, Jian Zhang. [Chemical constituents of Eupatorium lindleyanum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Apr; 37(7):937-40. doi: . [PMID: 22792793]
  • Anat Elmann, Sharon Mordechay, Hilla Erlank, Alona Telerman, Miriam Rindner, Rivka Ofir. Anti-neuroinflammatory effects of the extract of Achillea fragrantissima. BMC complementary and alternative medicine. 2011 Oct; 11(?):98. doi: 10.1186/1472-6882-11-98. [PMID: 22018032]
  • Gjoshe Stefkov, Svetlana Kulevanova, Biljana Miova, Suzana Dinevska-Kjovkarovska, Per Mølgaard, Anna K Jäger, Knud Josefsen. Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. Pharmaceutical biology. 2011 Sep; 49(9):885-92. doi: 10.3109/13880209.2011.552187. [PMID: 21619454]
  • Seed Niazmand, Maryam Esparham, Tahereh Hassannia, Mohammad Derakhshan. Cardiovascular effects of Teucrium polium L. extract in rabbit. Pharmacognosy magazine. 2011 Jul; 7(27):260-4. doi: 10.4103/0973-1296.84244. [PMID: 21969799]
  • Ahmad R Gohari, Soodabeh Saeidnia, Maryam Malmir, Abbass Hadjiakhoondi, Yousef Ajani. Flavones and rosmarinic acid from Salvia limbata. Natural product research. 2010 Dec; 24(20):1902-6. doi: 10.1080/14786411003766912. [PMID: 21108116]
  • Ai-Hua Zhao, Rong-Tao Li, Bei Jiang, Ji-Xia Zhang, Qin-Shi Zhao, Han-Dong Sun. Three new compounds from Isodon melissoides. Journal of Asian natural products research. 2005 Apr; 7(2):151-6. doi: 10.1080/1028602042000204108. [PMID: 15621618]
  • Sheng Lin, Qi-Wei Zhang, Ning-Ning Zhang, Yong-Xin Zhang. [Determination of flavonoids in buds of Herba Artemisiae Scopariae by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Apr; 30(8):591-4. doi: . [PMID: 16011282]
  • Tsuneatsu Nagao, Fumiko Abe, Junei Kinjo, Hikaru Okabe. Antiproliferative constituents in plants 10. Flavones from the leaves of Lantana montevidensis Briq. and consideration of structure-activity relationship. Biological & pharmaceutical bulletin. 2002 Jul; 25(7):875-9. doi: 10.1248/bpb.25.875. [PMID: 12132661]
  • Qi-wei Zhang, Yong-xi Zhang, Ying Zhang, Yong-qing Xiao, Zhi-min Wang. [Studies on chemical constituents in buds of Artemisia scoparia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2002 Mar; 27(3):202-4. doi: . [PMID: 12774401]
  • H Blomgren, G Kling-Andersson. Growth inhibition of human malignant glioma cells in vitro by agents which interfere with biosynthesis of eicosanoids. Anticancer research. 1992 May; 12(3):981-6. doi: NULL. [PMID: 1622156]