Salinomycin (BioDeep_00000002551)

   

natural product


代谢物信息卡片


AKOS032949878

化学式: C42H70O11 (750.4918)
中文名称: 盐霉素
谱图信息: 最多检出来源 Escherichia coli(natural_products) 26.83%

分子结构信息

SMILES: CCC(C(=O)O)C1CCC(C)C(C(C)C(O)C(C)C(=O)C(CC)C2OC3(C=CC(O)C4(CCC(C)(C5CCC(O)(CC)C(C)O5)O4)O3)C(C)CC2C)O1
InChI: InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic
Same as: D08502

同义名列表

4 个代谢物同义名

Salinomycin; AKOS032949878; Salinomicina; Salinomycin



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ABCB1, AKT1, CAT, CCND1, CDH1, CTNNB1, MAPK8, MTOR, MYC, PIK3CA, POU5F1, TP53, VIM
Peripheral membrane protein 1 MTOR
Endoplasmic reticulum membrane 1 MTOR
Nucleus 11 AKT1, CCND1, CDH1, CTNNB1, MAPK8, MTOR, MYC, NANOG, PARP1, POU5F1, TP53
cytosol 13 AKT1, CAT, CCND1, CD44, CDH1, CTNNB1, MAPK8, MTOR, PARP1, PIK3CA, POU5F1, TP53, VIM
dendrite 1 MTOR
nuclear body 1 PARP1
phagocytic vesicle 2 MTOR, VIM
trans-Golgi network 1 CDH1
centrosome 3 CCND1, CTNNB1, TP53
nucleoplasm 11 AKT1, CCND1, CDH1, CTNNB1, MAPK8, MTOR, MYC, NANOG, PARP1, POU5F1, TP53
Cell membrane 7 ABCB1, AKT1, CD44, CDH1, CTNNB1, LRP6, VIM
Cytoplasmic side 1 MTOR
lamellipodium 4 AKT1, CDH1, CTNNB1, PIK3CA
Early endosome membrane 1 LRP6
Multi-pass membrane protein 2 ABCB1, PROM1
Golgi apparatus membrane 1 MTOR
Synapse 3 CTNNB1, LRP6, MAPK8
cell cortex 2 AKT1, CTNNB1
cell junction 2 CDH1, CTNNB1
cell surface 4 ABCB1, CD44, LRP6, PROM1
glutamatergic synapse 3 AKT1, CDH1, CTNNB1
Golgi apparatus 2 CD44, CDH1
Golgi membrane 1 MTOR
lysosomal membrane 1 MTOR
neuronal cell body 1 LRP6
postsynapse 2 AKT1, CDH1
presynaptic membrane 1 CTNNB1
Cytoplasm, cytosol 1 PARP1
Lysosome 1 MTOR
endosome 1 CDH1
plasma membrane 9 ABCB1, AKT1, CD44, CDH1, CTNNB1, LRP6, PIK3CA, PROM1, VIM
Membrane 11 ABCB1, AKT1, CAT, CD44, CDH1, CTNNB1, LRP6, MTOR, MYC, PARP1, TP53
apical plasma membrane 3 ABCB1, CD44, PROM1
axon 3 CCK, MAPK8, VIM
basolateral plasma membrane 2 CD44, CTNNB1
extracellular exosome 7 ABCB1, CAT, CD44, CDH1, CTNNB1, PROM1, VIM
Lysosome membrane 1 MTOR
endoplasmic reticulum 3 LRP6, PROM1, TP53
extracellular space 3 CCK, IL6, PROM1
perinuclear region of cytoplasm 3 CDH1, CTNNB1, PIK3CA
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 2 CDH1, CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 2 CCND1, CTNNB1
intercalated disc 1 PIK3CA
mitochondrion 4 CAT, PARP1, POU5F1, TP53
protein-containing complex 6 AKT1, CAT, CTNNB1, MYC, PARP1, TP53
intracellular membrane-bounded organelle 2 CAT, NANOG
Microsome membrane 1 MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 CD44, CDH1
Secreted 3 CCK, CD44, IL6
extracellular region 6 CAT, CCK, CD44, CDH1, IL6, LRP6
cytoplasmic side of plasma membrane 1 CDH1
Mitochondrion outer membrane 1 MTOR
Single-pass membrane protein 2 CD44, LRP6
mitochondrial outer membrane 1 MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 CAT, TP53
transcription regulator complex 4 CTNNB1, PARP1, POU5F1, TP53
photoreceptor outer segment 1 PROM1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Nucleus membrane 1 CCND1
nuclear membrane 2 CCND1, CDH1
actin cytoskeleton 1 CDH1
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
cytoplasmic vesicle 1 LRP6
microtubule cytoskeleton 1 AKT1
nucleolus 4 MYC, NANOG, PARP1, TP53
Wnt signalosome 2 CTNNB1, LRP6
apical part of cell 1 CTNNB1
cell-cell junction 2 AKT1, CTNNB1
vesicle 2 AKT1, PROM1
postsynaptic membrane 1 CTNNB1
Apical cell membrane 2 ABCB1, PROM1
Membrane raft 1 LRP6
Cytoplasm, cytoskeleton 3 CTNNB1, TP53, VIM
focal adhesion 4 CAT, CD44, CTNNB1, VIM
spindle 1 AKT1
Cell junction, adherens junction 2 CDH1, CTNNB1
flotillin complex 2 CDH1, CTNNB1
Peroxisome 2 CAT, VIM
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
fascia adherens 1 CTNNB1
intermediate filament 1 VIM
lateral plasma membrane 2 CDH1, CTNNB1
neuron projection 1 VIM
ciliary basal body 1 AKT1
cilium 1 PROM1
chromatin 5 MYC, NANOG, PARP1, POU5F1, TP53
cell leading edge 1 VIM
cell projection 1 CD44
cell periphery 1 CTNNB1
Chromosome 1 PARP1
cytoskeleton 1 VIM
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
Cell projection, cilium, photoreceptor outer segment 1 PROM1
Golgi apparatus, trans-Golgi network 1 CDH1
Nucleus, nucleolus 2 MYC, PARP1
spindle pole 1 CTNNB1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
postsynaptic density, intracellular component 1 CTNNB1
Cell projection, microvillus membrane 1 PROM1
microvillus membrane 2 CTNNB1, PROM1
site of double-strand break 2 PARP1, TP53
nuclear envelope 3 MTOR, MYC, PARP1
Endomembrane system 2 CTNNB1, MTOR
microvillus 2 CD44, PROM1
microtubule organizing center 1 VIM
Cell projection, microvillus 1 CD44
Nucleus, nucleoplasm 1 MYC
euchromatin 1 CTNNB1
germ cell nucleus 1 TP53
replication fork 1 TP53
intermediate filament cytoskeleton 1 VIM
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
secretory granule membrane 1 CD44
endoplasmic reticulum lumen 1 IL6
nuclear matrix 2 TP53, VIM
transcription repressor complex 2 CCND1, TP53
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
RNA polymerase II transcription repressor complex 1 MYC
beta-catenin-TCF complex 1 CTNNB1
anaphase-promoting complex 1 CDH1
Nucleus matrix 1 VIM
presynaptic active zone cytoplasmic component 1 CTNNB1
endoplasmic reticulum-Golgi intermediate compartment 1 PROM1
[Isoform 2]: Nucleus 1 CDH1
[Isoform 1]: Nucleus 1 TP53
protein-DNA complex 2 CTNNB1, PARP1
external side of apical plasma membrane 1 ABCB1
basal dendrite 1 MAPK8
apical junction complex 1 CDH1
photoreceptor outer segment membrane 1 PROM1
prominosome 1 PROM1
Rough endoplasmic reticulum 1 MYC
Cell junction, desmosome 1 CDH1
desmosome 1 CDH1
Cytoplasmic vesicle, phagosome 1 MTOR
catenin complex 2 CDH1, CTNNB1
Wnt-Frizzled-LRP5/6 complex 1 LRP6
site of DNA damage 1 PARP1
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
lamellipodium membrane 1 CD44
Myc-Max complex 1 MYC
catalase complex 1 CAT
macrophage migration inhibitory factor receptor complex 1 CD44
interleukin-6 receptor complex 1 IL6
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
cyclin D1-CDK4 complex 1 CCND1
beta-catenin-TCF7L2 complex 1 CTNNB1
cyclin D1-CDK6 complex 1 CCND1
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
nucleoplasmic reticulum 1 MYC


文献列表

  • Longhai Du, Yanlong Xu, Binxu Han, Yu Wang, Qingmin Zeng, Minghao Shao, Zuochong Yu. EGFR-targeting peptide conjugated polymer-lipid hybrid nanoparticles for delivery of salinomycin to osteosarcoma. Journal of cancer research and therapeutics. 2023 Dec; 19(6):1544-1551. doi: 10.4103/jcrt.jcrt_2503_22. [PMID: 38156920]
  • Tatyana I Rokitskaya, Alexander M Firsov, Ljudmila S Khailova, Elena A Kotova, Yuri N Antonenko. Selectivity of cation transport across lipid membranes by the antibiotic salinomycin. Biochimica et biophysica acta. Biomembranes. 2023 Jun; 1865(7):184182. doi: 10.1016/j.bbamem.2023.184182. [PMID: 37276926]
  • Jaewang Lee, Jong-Lyel Roh. Promotion of ferroptosis in head and neck cancer with divalent metal transporter 1 inhibition or salinomycin. Human cell. 2023 Mar; ?(?):. doi: 10.1007/s13577-023-00890-x. [PMID: 36890422]
  • Viktoria Martyniuk, Vira Khoma, Tetiana Matskiv, Kateryna Yunko, Lesya Gnatyshyna, Oksana Stoliar, Caterina Faggio. Combined effect of microplastic, salinomycin and heating on Unio tumidus. Environmental toxicology and pharmacology. 2023 Jan; 98(?):104068. doi: 10.1016/j.etap.2023.104068. [PMID: 36680920]
  • Linzhou Yin, Pengyu Liu, Yue Jin, Zunxi Ning, Yiren Yang, Huiyuan Gao. Ferroptosis-related small-molecule compounds in cancer therapy: Strategies and applications. European journal of medicinal chemistry. 2022 Dec; 244(?):114861. doi: 10.1016/j.ejmech.2022.114861. [PMID: 36332549]
  • Yuri N Antonenko, Marta Jędrzejczyk, Tatyana I Rokitskaya, Ljudmila S Khailova, Elena A Kotova, Adam Huczyński. Rate of translocation across lipid bilayer of triphenylphosphonium-linked salinomycin derivatives contributes significantly to their K+/H+ exchange activity on membranes. Bioelectrochemistry (Amsterdam, Netherlands). 2022 Jun; 145(?):108089. doi: 10.1016/j.bioelechem.2022.108089. [PMID: 35299152]
  • Suparna Mercy Basu, Sunil Kumar Yadava, Ruby Singh, Jyotsnendu Giri. Lipid nanocapsules co-encapsulating paclitaxel and salinomycin for eradicating breast cancer and cancer stem cells. Colloids and surfaces. B, Biointerfaces. 2021 Aug; 204(?):111775. doi: 10.1016/j.colsurfb.2021.111775. [PMID: 33940518]
  • Farhad Rostami, Kamran Taherpour, Hossein Ali Ghasemi, Mohammad Akbari Gharaei, Hassan Shirzadi. Effects of Scrophularia striata hydroalcoholic extract in comparison to salinomycin on growth performance, intestinal health and immunity in broiler chickens following a mixed-species Eimeria challenge. Veterinary parasitology. 2021 May; 293(?):109417. doi: 10.1016/j.vetpar.2021.109417. [PMID: 33819905]
  • Hussein M El-Zaher, Sherif Y Eid, Mahmoud M Shaaban, Omar A Ahmed-Farid, Ahmed M Abd El Tawab, Mostafa S A Khattab. Ovarian activity and antioxidant indices during estrous cycle of Barki ewes under effect of thyme, celery and salinomycin as feed additives. Zygote (Cambridge, England). 2021 Apr; 29(2):155-160. doi: 10.1017/s0967199420000611. [PMID: 33228827]
  • Huan Shen, Changquan Calvin Sun, Lichun Kang, Xiaoyue Tan, Peng Shi, Lingyu Wang, Ergang Liu, Junbo Gong. Low-dose salinomycin inhibits breast cancer metastasis by repolarizing tumor hijacked macrophages toward the M1 phenotype. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2021 Feb; 157(?):105629. doi: 10.1016/j.ejps.2020.105629. [PMID: 33176191]
  • Reza Abbasi, Bahman Abdi-Hachesoo, Seyed Mostafa Razavi, Fatemeh Namazi, Saeed Nazifi. In vitro and in vivo activity of cinnamaldehyde against Eimeria kofoidi in chukar partridge (Alectoris chukar). Experimental parasitology. 2020 Nov; 218(?):107978. doi: 10.1016/j.exppara.2020.107978. [PMID: 32853633]
  • Sai Kiran S S Pindiprolu, Chirravuri S Phani Kumar, Venu Sampath Kumar Golla, Likitha P, Shreyas Chandra K, Esub Basha S K, Ramachandra R K. Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent. Medical hypotheses. 2020 Oct; 143(?):109858. doi: 10.1016/j.mehy.2020.109858. [PMID: 32516655]
  • K W Bafundo, A B Johnson, G F Mathis. The Effects of a Combination of Quillaja saponaria and Yucca schidigera on Eimeria spp. in Broiler Chickens. Avian diseases. 2020 09; 64(3):300-304. doi: 10.1637/aviandiseases-d-20-00016. [PMID: 33205178]
  • Michał Sulik, Ewa Maj, Joanna Wietrzyk, Adam Huczyński, Michał Antoszczak. Synthesis and Anticancer Activity of Dimeric Polyether Ionophores. Biomolecules. 2020 07; 10(7):. doi: 10.3390/biom10071039. [PMID: 32664671]
  • Aleksandr Ianevski, Rouan Yao, Mona Høysæter Fenstad, Svetlana Biza, Eva Zusinaite, Tuuli Reisberg, Hilde Lysvand, Kirsti Løseth, Veslemøy Malm Landsem, Janne Fossum Malmring, Valentyn Oksenych, Sten Even Erlandsen, Per Arne Aas, Lars Hagen, Caroline H Pettersen, Tanel Tenson, Jan Egil Afset, Svein Arne Nordbø, Magnar Bjørås, Denis E Kainov. Potential Antiviral Options against SARS-CoV-2 Infection. Viruses. 2020 06; 12(6):. doi: 10.3390/v12060642. [PMID: 32545799]
  • Saad A Alkahtani, Ashraf M Mahmoud, Mater H Mahnashi, Ramadan Ali, Mohamed M El-Wekil. Facile fabrication of a novel 3D rose like lanthanum doped zirconia decorated reduced graphene oxide nanosheets: An efficient electro-catalyst for electrochemical reduction of futuristic anti-cancer drug salinomycin during pharmacokinetic study. Biosensors & bioelectronics. 2020 Feb; 150(?):111849. doi: 10.1016/j.bios.2019.111849. [PMID: 31733999]
  • Jianwen Zhou, Mingshuang Sun, Shanshan Jin, Li Fan, Wenquan Zhu, Xiaoyu Sui, Lixin Cao, Chunrong Yang, Cuiyan Han. Combined using of paclitaxel and salinomycin active targeting nanostructured lipid carriers against non-small cell lung cancer and cancer stem cells. Drug delivery. 2019 Dec; 26(1):281-289. doi: 10.1080/10717544.2019.1580799. [PMID: 30880491]
  • Srinivasu B, V Chinni Preetam, Gurram Srinivas, D Srinivas Rao. Effect of Cocciban herbal coccidiostats on hematobiochemical, fecal parameters and cecal histopathology of broiler chicken. Tropical animal health and production. 2019 Jul; 51(6):1375-1381. doi: 10.1007/s11250-019-01831-3. [PMID: 30729387]
  • Yongmei Zhao, Wei Zhao, Yi Chieh Lim, Tianqing Liu. Salinomycin-Loaded Gold Nanoparticles for Treating Cancer Stem Cells by Ferroptosis-Induced Cell Death. Molecular pharmaceutics. 2019 06; 16(6):2532-2539. doi: 10.1021/acs.molpharmaceut.9b00132. [PMID: 31009228]
  • Jayant Dewangan, Sonal Srivastava, Sakshi Mishra, Aman Divakar, Sadan Kumar, Srikanta Kumar Rath. Salinomycin inhibits breast cancer progression via targeting HIF-1α/VEGF mediated tumor angiogenesis in vitro and in vivo. Biochemical pharmacology. 2019 06; 164(?):326-335. doi: 10.1016/j.bcp.2019.04.026. [PMID: 31028743]
  • Yedukondalu Nalli, Mohd Saleem Dar, Nasima Bano, Javeed Ur Rasool, Aminur R Sarkar, Junaid Banday, Aadil Qadir Bhat, Basit Rafia, Ram A Vishwakarma, Mohd Jamal Dar, Asif Ali. Analyzing the role of cannabinoids as modulators of Wnt/β-catenin signaling pathway for their use in the management of neuropathic pain. Bioorganic & medicinal chemistry letters. 2019 05; 29(9):1043-1046. doi: 10.1016/j.bmcl.2019.03.013. [PMID: 30871771]
  • Michał Antoszczak. A comprehensive review of salinomycin derivatives as potent anticancer and anti-CSCs agents. European journal of medicinal chemistry. 2019 Mar; 166(?):48-64. doi: 10.1016/j.ejmech.2019.01.034. [PMID: 30684870]
  • Jie Li, Liang Zhai, Jiyang Xue, Hai Zhang, Fangyuan Xie, Jie Gao. Effects of D-α-tocopherol polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles on the absorption, pharmacokinetics, and pharmacodynamics of salinomycin sodium. Anti-cancer drugs. 2019 01; 30(1):72-80. doi: 10.1097/cad.0000000000000695. [PMID: 30239423]
  • Lei Liu, Qifei Wang, Jun Mao, Tao Qin, Yan Sun, Jinfeng Yang, Yanyan Han, Lianhong Li, Quanlin Li. Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells. Chemico-biological interactions. 2018 Dec; 296(?):145-153. doi: 10.1016/j.cbi.2018.09.018. [PMID: 30273566]
  • Yejin Jang, Jin Soo Shin, Yi-Seul Yoon, Yun Young Go, Hye Won Lee, Oh Seung Kwon, Sehee Park, Man-Seong Park, Meehyein Kim. Salinomycin Inhibits Influenza Virus Infection by Disrupting Endosomal Acidification and Viral Matrix Protein 2 Function. Journal of virology. 2018 12; 92(24):. doi: 10.1128/jvi.01441-18. [PMID: 30282713]
  • Fangyi Chen, Yibin Zeng, Xiaoxia Qi, Yanchao Chen, Zhe Ge, Zengxin Jiang, Xinchao Zhang, Yinmei Dong, Huaiwen Chen, Zuochong Yu. Targeted salinomycin delivery with EGFR and CD133 aptamers based dual-ligand lipid-polymer nanoparticles to both osteosarcoma cells and cancer stem cells. Nanomedicine : nanotechnology, biology, and medicine. 2018 10; 14(7):2115-2127. doi: 10.1016/j.nano.2018.05.015. [PMID: 29898423]
  • R M Tonda, J K Rubach, B S Lumpkins, G F Mathis, M J Poss. Effects of tannic acid extract on performance and intestinal health of broiler chickens following coccidiosis vaccination and/or a mixed-species Eimeria challenge. Poultry science. 2018 Sep; 97(9):3031-3042. doi: 10.3382/ps/pey158. [PMID: 29767789]
  • Xingxing Yuan, Bingyu Wang, Lei Yang, Yali Zhang. The role of ROS-induced autophagy in hepatocellular carcinoma. Clinics and research in hepatology and gastroenterology. 2018 09; 42(4):306-312. doi: 10.1016/j.clinre.2018.01.005. [PMID: 29544680]
  • Jie Zhou, Jin Sun, Huaiwen Chen, Qing Peng. Promoted delivery of salinomycin sodium to lung cancer cells by dual targeting PLGA hybrid nanoparticles. International journal of oncology. 2018 Sep; 53(3):1289-1300. doi: 10.3892/ijo.2018.4474. [PMID: 30015824]
  • Dewen Leng, Jun Hu, Xiaolong Huang, Wei He, Yuan Wang, Mei Liu. Promoted Delivery of Salinomycin to Lung Cancer Through Epidermal Growth Factor Receptor Aptamers Coupled DSPE-PEG2000 Nanomicelles. Journal of nanoscience and nanotechnology. 2018 Aug; 18(8):5242-5251. doi: 10.1166/jnn.2018.15424. [PMID: 29458573]
  • Gonzalo J Diaz, Yandy Aguillón, Amparo Cortés. Effects on health, performance, and tissue residues of the ionophore antibiotic salinomycin in finishing broilers (21 to 38 d). Poultry science. 2018 Jun; 97(6):1922-1928. doi: 10.3382/ps/pey069. [PMID: 29554327]
  • Yi-Bin Zeng, Zuo-Chong Yu, Yan-Ni He, Tong Zhang, Ling-Bo Du, Yin-Mei Dong, Huai-Wen Chen, Ying-Ying Zhang, Wu-Qing Wang. Salinomycin-loaded lipid-polymer nanoparticles with anti-CD20 aptamers selectively suppress human CD20+ melanoma stem cells. Acta pharmacologica Sinica. 2018 Feb; 39(2):261-274. doi: 10.1038/aps.2017.166. [PMID: 29388568]
  • Kalina Kamenova, Yordanka Gluhcheva, Ivelin Vladov, Silviya Stoykova, Juliana Ivanova. Ameliorative effect of the anticancer agent salinomycin on cadmium-induced hepatotoxicity and renal dysfunction in mice. Environmental science and pollution research international. 2018 Feb; 25(4):3616-3627. doi: 10.1007/s11356-017-0755-y. [PMID: 29164462]
  • T De Mil, M Devreese, A Maes, S De Saeger, P De Backer, S Croubels. Influence of mycotoxin binders on the oral bioavailability of tylosin, doxycycline, diclazuril, and salinomycin in fed broiler chickens. Poultry science. 2017 Jul; 96(7):2137-2144. doi: 10.3382/ps/pew503. [PMID: 28160001]
  • Jun Li, Wenqing Xu, Xiaoli Yuan, Huaiwen Chen, Hao Song, Bingquan Wang, Jun Han. Polymer-lipid hybrid anti-HER2 nanoparticles for targeted salinomycin delivery to HER2-positive breast cancer stem cells and cancer cells. International journal of nanomedicine. 2017; 12(?):6909-6921. doi: 10.2147/ijn.s144184. [PMID: 29075110]
  • Michal Antoszczak, Ewa Maj, Natalia Kleczewska, Joanna Wietrzyk, Lech Celewicz, Adam Huczynski. Differences in Antiproliferative Activity Between Salinomycin-AZT Conjugates Obtained via 'Click' and Esterification Reactions. Medicinal chemistry (Shariqah (United Arab Emirates)). 2017; 13(2):127-136. doi: 10.2174/1573406412666160823165522. [PMID: 27557629]
  • Enric Xipell, Marisol Gonzalez-Huarriz, Juan Jose Martinez de Irujo, Antonia García-Garzón, Fred F Lang, Hong Jiang, Juan Fueyo, Candelaria Gomez-Manzano, Marta M Alonso. Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma. Oncotarget. 2016 May; 7(21):30626-41. doi: 10.18632/oncotarget.8905. [PMID: 27121320]
  • Chenyang Lu, Xiaojie Zhang, Ming Jiang, Linquan Bai. Enhanced salinomycin production by adjusting the supply of polyketide extender units in Streptomyces albus. Metabolic engineering. 2016 May; 35(?):129-137. doi: 10.1016/j.ymben.2016.02.012. [PMID: 26969249]
  • Xiaoli Huang, Björn Borgström, Sebastian Kempengren, Lo Persson, Cecilia Hegardt, Daniel Strand, Stina Oredsson. Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs. BMC cancer. 2016 Feb; 16(?):145. doi: 10.1186/s12885-016-2142-3. [PMID: 26906175]
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