Benzamide (BioDeep_00000002325)
Secondary id: BioDeep_00000405587
human metabolite Endogenous PANOMIX_OTCML-2023
代谢物信息卡片
Trimethobenzamide hydrochloride
化学式: C7H7NO (121.0528)
中文名称: 苯甲酰胺
谱图信息:
最多检出来源 Homo sapiens(lipidsearch) 24.98%
分子结构信息
SMILES: C1=CC=C(C=C1)C(=O)N
InChI: InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
描述信息
Benzamide is an intermediate in the Benzoate degradation via CoA ligation. Benzamides are a class of chemical compounds derived from Benzamid, the carbonic acid amide of benzoic acid. In psychiatry some substituted benzamides are therapeutically used as neuroleptics and/or antipsychotics (wikipedia).
Benzamide is an intermediate in the Benzoate degradation via CoA ligation.
CONFIDENCE standard compound; INTERNAL_ID 8080
KEIO_ID B009
Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].
同义名列表
20 个代谢物同义名
Trimethobenzamide hydrochloride; Benzamide (acd/name 4.0); Amid kyseliny benzoove; Phenyl carboxyamide; Benzoic acid amide; Benzenecarboxamide; Phenylcarboxyamide; Phenylcarboxamide; Benzoate amide; Benzoylamide; Benzoic Acid; PHC(=O)NH2; PHC(O)NH2; Benzamide; benzoate; Tigan; Benzamide; Phenylamide; Benzamide; Benzamide
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:28179
- KEGG: C09815
- KEGGdrug: D70176
- PubChem: 2331
- HMDB: HMDB0004461
- Metlin: METLIN44739
- ChEMBL: CHEMBL267373
- Wikipedia: Benzamide
- MetaCyc: SAM
- KNApSAcK: C00042277
- foodb: FDB023373
- chemspider: 2241
- CAS: 55738-52-8
- CAS: 55-21-0
- MoNA: SM808001
- MoNA: KO002438
- MoNA: KO002439
- MoNA: KO002442
- MoNA: KO002441
- MoNA: KO002440
- PMhub: MS000002349
- PubChem: 12003
- PDB-CCD: UNU
- 3DMET: B01116
- NIKKAJI: J1.374I
- RefMet: Benzamide
- medchemexpress: HY-Z0283
- KNApSAcK: 28179
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
9 个相关的物种来源信息
- 45005 - Colchicum autumnale: 10.1055/S-0028-1097251
- 452779 - Haplophyllum obtusifolium:
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-012-0464-Y
- 16752 - Houttuynia cordata: 10.1248/CPB.57.1227
- 40717 - Paeonia peregrina: 10.3406/LINLY.1891.15426
- 1226109 - Sarcomelicope argyrophylla: 10.1055/S-2007-969594
- 1883 - Streptomyces: 10.3390/MOLECULES23051032
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yi-Dan Ma, Huan Zhou, Guo-Tai Lin, Ke-Huan Wu, Gong Xu, Xili Liu, Dan Xu. Design, Synthesis, and Fungicidal Activities of Novel N-(Pyrazol-5-yl)benzamide Derivatives Containing a Diphenylamine Moiety.
Journal of agricultural and food chemistry.
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Journal of agricultural and food chemistry.
2024 Jan; 72(3):1527-1538. doi:
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Molecular pharmaceutics.
2023 Feb; 20(2):1015-1024. doi:
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European journal of cell biology.
2012 Mar; 91(3):161-70. doi:
10.1016/j.ejcb.2011.11.003. [PMID: 22306377] - Verónica Rachel Olate, Mariano Walter Pertino, Cristina Theoduloz, Erdem Yesilada, Francisco Monsalve, Paulo González, Daniel Droguett, Pascal Richomme, A Hamid Hadi, Guillermo Schmeda-Hirschmann. New gastroprotective labdeneamides from (4S,9R,10R) methyl 18-carboxy-labda-8,13(E)-diene-15-oate.
Planta medica.
2012 Mar; 78(4):362-7. doi:
10.1055/s-0031-1280453. [PMID: 22250049] - Zhigang Wang, Xiaobing Dou, Dongfang Gu, Chen Shen, Tong Yao, Van Nguyen, Carol Braunschweig, Zhenyuan Song. 4-Hydroxynonenal differentially regulates adiponectin gene expression and secretion via activating PPARγ and accelerating ubiquitin-proteasome degradation.
Molecular and cellular endocrinology.
2012 Feb; 349(2):222-31. doi:
10.1016/j.mce.2011.10.027. [PMID: 22085560] - Sylvie Mavel, Zoya Mincheva, Nathalie Méheux, Yvan Carcenac, Denis Guilloteau, Mohamed Abarbri, Patrick Emond. QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT).
Bioorganic & medicinal chemistry.
2012 Feb; 20(4):1388-95. doi:
10.1016/j.bmc.2012.01.014. [PMID: 22300887] - D P K Ng, A Salim, Y Liu, L Zou, F G Xu, S Huang, H Leong, C N Ong. A metabolomic study of low estimated GFR in non-proteinuric type 2 diabetes mellitus.
Diabetologia.
2012 Feb; 55(2):499-508. doi:
10.1007/s00125-011-2339-6. [PMID: 22038517] - Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita, Takashi Usui. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Feb; 40(2):276-82. doi:
10.1124/dmd.111.042614. [PMID: 22031623] - Dorothy B Colagiovanni, Daniel W Drolet, Emilie Langlois-Forget, Marie-Pier Piché, Doug Looker, Gary J Rosenthal. A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma.
Regulatory toxicology and pharmacology : RTP.
2012 Feb; 62(1):115-24. doi:
10.1016/j.yrtph.2011.12.012. [PMID: 22210450] - R Pili, B Salumbides, M Zhao, S Altiok, D Qian, J Zwiebel, M A Carducci, M A Rudek. Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours.
British journal of cancer.
2012 Jan; 106(1):77-84. doi:
10.1038/bjc.2011.527. [PMID: 22134508] - H Matsushita, M Matsuzaki, X-J Han, T-I Nishiki, I Ohmori, H Michiue, H Matsui, K Tomizawa. Antidepressant-like effect of sildenafil through oxytocin-dependent cyclic AMP response element-binding protein phosphorylation.
Neuroscience.
2012 Jan; 200(?):13-8. doi:
10.1016/j.neuroscience.2011.11.001. [PMID: 22088430] - Sugunadevi Sakkiah, Chandrasekaran Meganathan, Young-Sik Sohn, Sundaraganesan Namadevan, Keun Woo Lee. Identification of important chemical features of 11β-hydroxysteroid dehydrogenase type1 inhibitors: application of ligand based virtual screening and density functional theory.
International journal of molecular sciences.
2012; 13(4):5138-5162. doi:
10.3390/ijms13045138. [PMID: 22606035] - Bruce C Campbell, Kathleen L Chan, Jong H Kim. Chemosensitization as a means to augment commercial antifungal agents.
Frontiers in microbiology.
2012; 3(?):79. doi:
10.3389/fmicb.2012.00079. [PMID: 22393330] - Li Shen, Michael Ciesielski, Swathi Ramakrishnan, Kiersten M Miles, Leigh Ellis, Paula Sotomayor, Protul Shrikant, Robert Fenstermaker, Roberto Pili. Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models.
PloS one.
2012; 7(1):e30815. doi:
10.1371/journal.pone.0030815. [PMID: 22303460] - Jueun Oh, Tao Yu, Soo Jeong Choi, Yanyan Yang, Heung Soo Baek, Soon Ae An, Lee Kyoung Kwon, Jinsol Kim, Ho Sik Rho, Song Seok Shin, Wahn Soo Choi, Sungyoul Hong, Jae Youl Cho. Syk/Src pathway-targeted inhibition of skin inflammatory responses by carnosic acid.
Mediators of inflammation.
2012; 2012(?):781375. doi:
10.1155/2012/781375. [PMID: 22577255] - Victor Fang, Lori D Wazny, Colette B Raymond. Hypoglycemics for the treatment of type 2 diabetes in patients with chronic kidney disease: a focus on new agents.
CANNT journal = Journal ACITN.
2012 Jan; 22(1):30-6; quiz 37. doi:
NULL. [PMID: 22558681] - Toshifumi Shiraga, Kanako Yajima, Takuya Teragaki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita, Takashi Usui. Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes.
Biological & pharmaceutical bulletin.
2012; 35(3):413-21. doi:
10.1248/bpb.35.413. [PMID: 22382330] - Jesper T Andreasen, John P Redrobe, Elsebet Ø Nielsen. Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: a comparison of SSR180711 and PNU-282987.
Pharmacology, biochemistry, and behavior.
2012 Jan; 100(3):624-9. doi:
10.1016/j.pbb.2011.11.004. [PMID: 22108649] - Yoshiyuki Iwatsuki, Takayuki Sato, Yumiko Moritani, Takeshi Shigenaga, Mami Suzuki, Tomihisa Kawasaki, Toshiyuki Funatsu, Seiji Kaku. Biochemical and pharmacological profile of darexaban, an oral direct factor Xa inhibitor.
European journal of pharmacology.
2011 Dec; 673(1-3):49-55. doi:
10.1016/j.ejphar.2011.10.009. [PMID: 22040919] - Mat Ropi Muktar, Norfaizah Osman, Khalijah Awang, Hazrina Hazni, Ahmad Kaleem Qureshi, A Hamid A Hadi, Kazuma Zaima, Hiroshi Morita, Marc Litaudon. Neonaucline, a new indole alkaloid from the leaves of Ochreinauclea maingayii (Hook. f.) Ridsd. (Rubiaceae).
Molecules (Basel, Switzerland).
2011 Dec; 17(1):267-74. doi:
10.3390/molecules17010267. [PMID: 22205092] - Juan L Vivero-Escoto, Kathryn M L Taylor-Pashow, Rachel C Huxford, Joseph Della Rocca, Christie Okoruwa, Hongyu An, Weili Lin, Wenbin Lin. Multifunctional mesoporous silica nanospheres with cleavable Gd(III) chelates as MRI contrast agents: synthesis, characterization, target-specificity, and renal clearance.
Small (Weinheim an der Bergstrasse, Germany).
2011 Dec; 7(24):3519-28. doi:
10.1002/smll.201100521. [PMID: 22069305] - Fukushi Hirayama, Hiroyuki Koshio, Tsukasa Ishihara, Shunichiro Hachiya, Keizo Sugasawa, Yuji Koga, Norio Seki, Ryouta Shiraki, Takeshi Shigenaga, Yoshiyuki Iwatsuki, Yumiko Moritani, Kenichi Mori, Takeshi Kadokura, Tomihisa Kawasaki, Yuzo Matsumoto, Shuichi Sakamoto, Shin-ichi Tsukamoto. Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor.
Journal of medicinal chemistry.
2011 Dec; 54(23):8051-65. doi:
10.1021/jm200868m. [PMID: 21995444] - Gary E Meininger, Russell Scott, Maria Alba, Yue Shentu, Edmund Luo, Himal Amin, Michael J Davies, Keith D Kaufman, Barry J Goldstein. Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes.
Diabetes care.
2011 Dec; 34(12):2560-6. doi:
10.2337/dc11-1200. [PMID: 21994424] - M D Cantley, P M Bartold, V Marino, D P Fairlie, G T Le, A J Lucke, D R Haynes. Histone deacetylase inhibitors and periodontal bone loss.
Journal of periodontal research.
2011 Dec; 46(6):697-703. doi:
10.1111/j.1600-0765.2011.01392.x. [PMID: 21745207] - Masakazu Ishii, Ryouta Iizuka, Yuji Kiuchi, Yasuo Mori, Shunichi Shimizu. Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity.
Molecular and cellular biochemistry.
2011 Dec; 358(1-2):1-11. doi:
10.1007/s11010-011-0913-3. [PMID: 21656126] - Roger N Gunn, Venkatesha Murthy, Ana M Catafau, Graham Searle, Santiago Bullich, Mark Slifstein, Daniele Ouellet, Stefano Zamuner, Raul Herance, Cristian Salinas, Ricardo Pardo-Lozano, Eugenii A Rabiner, Magi Farre, Marc Laruelle. Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1.
Synapse (New York, N.Y.).
2011 Dec; 65(12):1319-32. doi:
10.1002/syn.20966. [PMID: 21688322] - Seung Hee Kang, Hee-Jeong Cho, Gayong Shim, Sangbin Lee, Su-Hyeon Kim, Han-Gon Choi, Chan-Wha Kim, Yu-Kyoung Oh. Cationic liposomal co-delivery of small interfering RNA and a MEK inhibitor for enhanced anticancer efficacy.
Pharmaceutical research.
2011 Dec; 28(12):3069-78. doi:
10.1007/s11095-011-0569-4. [PMID: 21879387] - C Ferreira, D C Soares, C B Barreto-Junior, M T Nascimento, L Freire-de-Lima, J C Delorenzi, M E F Lima, G C Atella, E Folly, T M U Carvalho, E M Saraiva, L H Pinto-da-Silva. Leishmanicidal effects of piperine, its derivatives, and analogues on Leishmania amazonensis.
Phytochemistry.
2011 Dec; 72(17):2155-64. doi:
10.1016/j.phytochem.2011.08.006. [PMID: 21885074] - Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B Langdon, Joel P Berger. Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs.
Molecular pharmacology.
2011 Dec; 80(6):1156-65. doi:
10.1124/mol.111.074401. [PMID: 21937665] - Xin Li, Lina Du, Chenyun Wang. Validation of a LC/MS/MS method for the quantitation of a new gastroprokinetic agent SHR116958 and its metabolite in rat plasma.
Die Pharmazie.
2011 Nov; 66(11):826-30. doi:
NULL. [PMID: 22204126] - Mohammed N Tantawy, Todd E Peterson, Carrie K Jones, Kari Johnson, Jerri M Rook, P Jeffrey Conn, Ronald M Baldwin, M Sib Ansari, Robert M Kessler. Impact of isoflurane anesthesia on D2 receptor occupancy by [18F]fallypride measured by microPET with a modified Logan plot.
Synapse (New York, N.Y.).
2011 Nov; 65(11):1173-80. doi:
10.1002/syn.20955. [PMID: 21584868] - Gregor Jost, Philipp Lengsfeld, Diana C Lenhard, Hubertus Pietsch, Joachim Hütter, Martin A Sieber. Viscosity of iodinated contrast agents during renal excretion.
European journal of radiology.
2011 Nov; 80(2):373-7. doi:
10.1016/j.ejrad.2011.02.003. [PMID: 21376497] - Sunipa Majumdar, Eric Buckles, John Estrada, Shahriar Koochekpour. Aberrant DNA methylation and prostate cancer.
Current genomics.
2011 Nov; 12(7):486-505. doi:
10.2174/138920211797904061. [PMID: 22547956] - Takeshi Fuchigami, Mamoru Haratake, Yasuhiro Magata, Terushi Haradahira, Morio Nakayama. Synthesis and characterization of [¹²⁵I]2-iodo N-[(S)-{(S)-1-methylpiperidin-2-yl}(phenyl)methyl]3-trifluoromethyl-benzamide as novel imaging probe for glycine transporter 1.
Bioorganic & medicinal chemistry.
2011 Nov; 19(21):6245-53. doi:
10.1016/j.bmc.2011.09.010. [PMID: 21975065] - Kazuyoshi Yoshii, Masamichi Hirayama, Toshifumi Nakamura, Ryoko Toda, Junko Hasegawa, Mineo Takei, Yukinori Mera, Yoshihiro Kawabata. Mechanism for distribution of acotiamide, a novel gastroprokinetic agent for the treatment of functional dyspepsia, in rat stomach.
Journal of pharmaceutical sciences.
2011 Nov; 100(11):4965-73. doi:
10.1002/jps.22649. [PMID: 21630282] - Sócrates Golzio dos Santos, Karine Formiga Queiroga, Adriana Maria Fernandes de Oliveira, Josean Fechine Tavares, Stanley Juan Chavez Gutierrez, Margareth de Fátima Formiga Melo Diniz, José Maria Barbosa-Filho, Marcelo Sobral da Silva. Blood matrix effects for male and female Wistar rats, in simultaneous HPLC-UV determination of riparin I and III from Aniba riparia (Nees) Mez. (Lauraceae).
Talanta.
2011 Oct; 86(?):233-40. doi:
10.1016/j.talanta.2011.09.008. [PMID: 22063536] - Victoria J Burton, Alan M Holmes, Loredana I Ciuclan, Alexander Robinson, Jan S Roger, Gabor Jarai, Andrew C Pearce, David C Budd. Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.
Blood.
2011 Oct; 118(17):4750-8. doi:
10.1182/blood-2011-05-347393. [PMID: 21900197] - A A Ensafi, H Karimi-Maleh, S Mallakpour, B Rezaei. Highly sensitive voltammetric sensor based on catechol-derivative-multiwall carbon nanotubes for the catalytic determination of captopril in patient human urine samples.
Colloids and surfaces. B, Biointerfaces.
2011 Oct; 87(2):480-8. doi:
10.1016/j.colsurfb.2011.06.013. [PMID: 21726986] - Masataka Kusunoki, Kazuhiko Tsutsumi, Daisuke Sato, Aki Nakamura, Satoshi Habu, Yuichi Mori, Munehiko Morishita, Takayuki Yonemoto, Tetsuro Miyata, Yutaka Nakaya, Takao Nakamura. Pioglitazone-induced body weight gain is prevented by combined administration with the lipoprotein lipase activator NO-1886.
European journal of pharmacology.
2011 Oct; 668(3):486-91. doi:
10.1016/j.ejphar.2011.07.030. [PMID: 21835171] - D Ouellet, S Sutherland, T Wang, P Griffini, V Murthy. First-time-in-human study with GSK1018921, a selective GlyT1 inhibitor: relationship between exposure and dizziness.
Clinical pharmacology and therapeutics.
2011 Oct; 90(4):597-604. doi:
10.1038/clpt.2011.154. [PMID: 21866096] - J Vasantha, P Soundararajan, N Vanitharani, G Kannan, P Thennarasu, G Neenu, C Umamaheswara Reddy. Safety and efficacy of nicotinamide in the management of hyperphosphatemia in patients on hemodialysis.
Indian journal of nephrology.
2011 Oct; 21(4):245-9. doi:
10.4103/0971-4065.83735. [PMID: 22022084] - Masataka Kusunoki, Kazuhiko Tsutsumi, Daisuke Sato, Aki Nakamura, Satoshi Habu, Yuichi Mori, Munehiko Morishita, Takayuki Yonemoto, Tetsuro Miyata, Yutaka Nakaya, Takao Nakamura. Activation of lipoprotein lipase increases serum high density lipoprotein 2 cholesterol and enlarges high density lipoprotein 2 particles in rats.
European journal of pharmacology.
2011 Oct; 668(1-2):337-9. doi:
10.1016/j.ejphar.2011.06.040. [PMID: 21756896] - San-Cher Chen, Jinn-Yuh Guh, Tai-Du Lin, Shean-Jaw Chiou, Chi-Ching Hwang, Yu-Min Ko, Lea-Yea Chuang. Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells.
Translational research : the journal of laboratory and clinical medicine.
2011 Oct; 158(4):214-24. doi:
10.1016/j.trsl.2011.06.002. [PMID: 21925118] - Cristina Romei, Silvia Di Prisco, Maurizio Raiteri, Luca Raiteri. Glycine release provoked by disturbed Na⁺, Na⁺ and Ca²⁺ homeostasis in cerebellar nerve endings: roles of Ca²⁺ channels, Na⁺/Ca²⁺ exchangers and GlyT2 transporter reversal.
Journal of neurochemistry.
2011 Oct; 119(1):50-63. doi:
10.1111/j.1471-4159.2011.07401.x. [PMID: 21790607] - Ljuba Iovkova-Berends, Carmen Wängler, Thomas Zöller, Georg Höfner, Klaus Theodor Wanner, Christian Rensch, Peter Bartenstein, Alexey Kostikov, Ralf Schirrmacher, Klaus Jurkschat, Björn Wängler. t-Bu2SiF-derivatized D2-receptor ligands: the first SiFA-containing small molecule radiotracers for target-specific PET-imaging.
Molecules (Basel, Switzerland).
2011 Sep; 16(9):7458-79. doi:
10.3390/molecules16097458. [PMID: 21892125] - Paul Hamberg, Margaret M Woo, Lin-Chi Chen, Jaap Verweij, Maria Grazia Porro, Lily Zhao, Wenkui Li, Diane van der Biessen, Sunil Sharma, Thomas Hengelage, Maja de Jonge. Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor.
Cancer chemotherapy and pharmacology.
2011 Sep; 68(3):805-13. doi:
10.1007/s00280-011-1693-x. [PMID: 21706316] - Gregory Valania, Manmeet Singh, Mara T Slawsky. Targeting hyponatremia and hemodynamics in acute decompensated heart failure: is there a role for vasopressin antagonists?.
Current heart failure reports.
2011 Sep; 8(3):198-205. doi:
10.1007/s11897-010-0035-3. [PMID: 21046492]
