Kanamycin (BioDeep_00000002010)

human metabolite blood metabolite Chemicals and Drugs Antibiotics

代谢物信息卡片

(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol

化学式: C18H36N4O11 (484.23804659999996)
中文名称: 卡那霉素A, 卡那霉素
谱图信息: 最多检出来源 Homo sapiens(feces) 31.6%

分子结构信息

SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N
InChI: InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1

描述信息

Kanamycin is only found in individuals that have used or taken this drug. It is an antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components. [PubChem]Aminoglycosides like kanamycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically Kanamycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.
A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07A - Intestinal antiinfectives > A07AA - Antibiotics
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01G - Aminoglycoside antibacterials
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic

同义名列表

17 个代谢物同义名

(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine; O-3-Amino-3-deoxy-a-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-a-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-α-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine; 4,6-Diamino-2-hydroxy-1,3-cyclohexylene 3,6-diamino-3,6-dideoxydi-D-glucopyranoside; 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6diamino-3,6-dideoxydi-alpha-D-glucoside; 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6diamino-3,6-dideoxydi-α-D-glucoside; 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6diamino-3,6-dideoxydi-a-D-glucoside; Kanamycin A monosulfate; Aminodeoxykanamycin; Nebramycin factor 5; KANAMYCIN SULFATE; Kanamycin base; Kanamycin a; kanamycin; Kantrex; KAN

数据库引用编号

20 个数据库交叉引用编号

ChEBI: CHEBI:17630
ChEBI: CHEBI:6104
KEGG: C01822
PubChem: 6032
PubChem: 815
HMDB: HMDB0015303
Metlin: METLIN43223
DrugBank: DB01172
ChEMBL: CHEMBL1384
Wikipedia: Kanamycin
MeSH: Kanamycin
KNApSAcK: C00018690
chemspider: 5810
CAS: 8063-07-8
CAS: 59-01-8
PMhub: MS000001653
PubChem: 4946
PDB-CCD: KAN
NIKKAJI: J4.492J
RefMet: Kanamycin

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
212299 - Elateriospermum tapos: 10.1021/NP070629G
9606 - Homo sapiens: -
1883 - Streptomyces: 10.1021/JA01548A077
68174 - Streptomyces anthocyanicus:
58343 - Streptomyces canus: 10.1021/JF305210U
1912 - Streptomyces hygroscopicus: 10.1021/NP400145U
1967 - Streptomyces kanamyceticus:
1916 - Streptomyces lividans:
54571 - Streptomyces venezuelae: 10.1007/S00253-007-1096-4

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Rekha Gahtori, Ankita H Tripathi, Garima Chand, Amit Pande, Penny Joshi, Ramesh Chandra Rai, Santosh K Upadhyay. Phytochemical Screening of Nyctanthes arbor-tristis Plant Extracts and Their Antioxidant and Antibacterial Activity Analysis. Applied biochemistry and biotechnology. 2024 Jan; 196(1):436-456. doi: 10.1007/s12010-023-04552-4. [PMID: 37140779]
Ziyan Yu, Yaxiao Liao, Jie Liu, Qin Wu, Yu Cheng, Ke Huang. A smartphone-based gold nanoparticle colorimetric sensing platform for kanamycin detection in food samples. Analytical methods : advancing methods and applications. 2023 08; 15(34):4282-4288. doi: 10.1039/d3ay01076g. [PMID: 37599591]
Mohammad Hossein Mirzaee, Masoumeh Emadpour. Advances in the Transformation of Cyclamen persicum Mill. Through Direct Regeneration Based on an Optimized Kanamycin Selection Scheme. Molecular biotechnology. 2023 May; ?(?):. doi: 10.1007/s12033-023-00758-3. [PMID: 37133706]
Jian Song, Kaiyu He, Bingcong Xing, Yong Pei, Dingnan Wang, Yang Wang, Shiyan Li, Jie Li, Weiwei Huan, Yiming Zhang, Bruce D Hammock. Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chip. Analytical chemistry. 2022 12; 94(50):17567-17576. doi: 10.1021/acs.analchem.2c03932. [PMID: 36458677]
Yue Liu, Xiaoxia Sun, Jincan Zhang, Feng Gao, Leilei Yu, Lina Dong, Gangli Zhang, Changxin Wu. Isolation and characterisation of Pulsatilla Radix-utilising bacteria Pediococcus pentosaceus PR-1 from human faeces. FEMS microbiology letters. 2022 10; 369(1):. doi: 10.1093/femsle/fnac089. [PMID: 36073496]
Jiali Zhang, Jing Zhang, Peiling Li, Yuan Gao, Qi Yu, Daojin Sun, Lingling Zhang, Siqi Wang, Jing Tian, Zhenxing Wang, Jiafu Jiang, Fadi Chen, Aiping Song. Development of a Transformation System and Locus Identification Pipeline for T-DNA in Chrysanthemum seticuspe, A Model Species for Hexaploid Cultivated Chrysanthemum. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911426. [PMID: 36232727]
Hongbo Dong, Min Wu, Shengwei Xiang, Tao Song, Ying Li, Bin Long, Chuanling Feng, Zheng Shi. Total Syntheses and Antibacterial Evaluations of Neocyclomorusin and Related Flavones. Journal of natural products. 2022 09; 85(9):2217-2225. doi: 10.1021/acs.jnatprod.2c00658. [PMID: 36062892]
Xiaocui Wu, Guangkun Tan, Jinghui Yang, Yinjuan Guo, Chengchen Huang, Wei Sha, Fangyou Yu. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022 Aug; 121(?):47-54. doi: 10.1016/j.ijid.2022.04.061. [PMID: 35523300]
Ratan W Jadhav, Sopan M Wagalgave, Bajarang V Kumbhar, Rushikesh M Khadake, Ambadas B Rode, Sidhanath V Bhosale, Sheshanath V Bhosale. Aminoglycoside antibiotic kanamycin functionalized tetraphenylethylene molecular probe for highly selective detection of bovine serum albumin protein. Scientific reports. 2022 Jul; 12(1):11526. doi: 10.1038/s41598-022-15890-4. [PMID: 35798871]
Mbarga Manga Joseph Arsene, Podoprigora Irina Viktorovna, Mefed Kirill Mikhaïlovitch, Anyutoulou Kitio Linda Davares, Kezimana Parfait, Manar Rehailia, Senyagin Alexander Nikolayevich, Girich Valentina Stefanovna, Souadkia Sarra, Khabadze Zurab Sulikoevich, Chernaia Zoya Anatolyevna, Das Shommiya. In vitro antimicrobial activity, antibioresistance reversal properties, and toxicity screen of ethanolic extracts of Heracleum mantegazzianum Sommier and Levier (giant hogweed), Centaurea jacea L. (brown knapweed), and Chenopodium album L. (Pigweed): Three invasive plants. Open veterinary journal. 2022 Jul; 12(4):584-594. doi: 10.5455/ovj.2022.v12.i4.22. [PMID: 36118725]
Gulzar A Rather, Dana Ayzenshtat, Paula Teper-Bamnolker, Manoj Kumar, Zohar Forotan, Dani Eshel, Samuel Bocobza. Advances in protoplast transfection promote efficient CRISPR/Cas9-mediated genome editing in tetraploid potato. Planta. 2022 Jun; 256(1):14. doi: 10.1007/s00425-022-03933-z. [PMID: 35713718]
Jia Fang, Hongmin Wu, Jianning Zhang, Song Mao, Haosong Shi, Dongzhen Yu, Zhengnong Chen, Kaiming Su, Yazhi Xing, Hongjun Dong, Haibo Shi. A reduced form of nicotinamide riboside protects the cochlea against aminoglycoside-induced ototoxicity by SIRT1 activation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Jun; 150(?):113071. doi: 10.1016/j.biopha.2022.113071. [PMID: 35658237]
Chaicharoen Tantanate, Supavat Talabthong, Phenluck Lamyai. Kanamycin Supplement for the Disaggregation of Platelet Clumps in EDTA-Dependent Pseudothrombocytopenia Specimens. Laboratory medicine. 2022 May; 53(3):e69-e73. doi: 10.1093/labmed/lmab090. [PMID: 34668538]
Xiaocui Wu, Guangkun Tan, Wei Sha, Haican Liu, Jinghui Yang, Yinjuan Guo, Xin Shen, Zheyuan Wu, Hongbo Shen, Fangyou Yu. Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures. Microbiology spectrum. 2022 04; 10(2):e0251621. doi: 10.1128/spectrum.02516-21. [PMID: 35311541]
M Hamdi Abdulkareem, I Abbas Abood, M Munis Dakheel. Antimicrobial Resistance of Tannin Extract against E. coli Isolates from Sheep. Archives of Razi Institute. 2022 Apr; 77(2):697-701. doi: 10.22092/ari.2022.356982.1955. [PMID: 36284977]
Ying Wang, Bing Wang, Xingliang Xiong, Shixiong Deng. A self-oriented beacon liquid crystal assay for kanamycin detection with AuNPs signal enhancement. Analytical methods : advancing methods and applications. 2022 01; 14(4):410-416. doi: 10.1039/d1ay01613j. [PMID: 35006220]
Yao Yao, Tao Hu, Chang Song, Chang Liu, Dezhao Kong, Cheng Huang, Jia Zhu, Wei Shen, Haiwei Shi, Sheng Tang. Multiply-amplified strategy for the ultrasensitive detection of kanamycin via aptamer-triggered three-dimensional G-quadruplex/Ni-Fe layered double oxide frame networks. Analytica chimica acta. 2021 Dec; 1187(?):339169. doi: 10.1016/j.aca.2021.339169. [PMID: 34753567]
Jianyu Hu, Hongjie Song, Jing Zhou, Rui Liu, Yi Lv. Metal-Tagged CRISPR/Cas12a Bioassay Enables Ultrasensitive and Highly Selective Evaluation of Kanamycin Bioaccumulation in Fish Samples. Analytical chemistry. 2021 10; 93(42):14214-14222. doi: 10.1021/acs.analchem.1c03094. [PMID: 34644046]
Qian Luo, Kunhao Qin, Fei Liu, Xiaodan Zheng, Yafang Ding, Chunting Zhang, Meiying Xu, Xin Liu, Yunlin Wei. Carbon dots derived from kanamycin sulfate with antibacterial activity and selectivity for Cr6+ detection. The Analyst. 2021 Mar; 146(6):1965-1972. doi: 10.1039/d0an02352c. [PMID: 33496685]
Yue Tang, Yang Hu, Pei Zhou, Chunxiao Wang, Han Tao, Yuangen Wu. Colorimetric Detection of Kanamycin Residue in Foods Based on the Aptamer-Enhanced Peroxidase-Mimicking Activity of Layered WS2 Nanosheets. Journal of agricultural and food chemistry. 2021 Mar; 69(9):2884-2893. doi: 10.1021/acs.jafc.1c00925. [PMID: 33646795]
Wenjiao Zhou, Lin Xu, Bingying Jiang. Target-initiated autonomous synthesis of metal-ion dependent DNAzymes for label-free and amplified fluorescence detection of kanamycin in milk samples. Analytica chimica acta. 2021 Mar; 1148(?):238195. doi: 10.1016/j.aca.2020.12.070. [PMID: 33516378]
Yagya P Subedi, Guillermo A Altenberg, Cheng-Wei T Chang. Advances in the development of connexin hemichannel inhibitors selective toward Cx43. Future medicinal chemistry. 2021 02; 13(4):379-392. doi: 10.4155/fmc-2020-0291. [PMID: 33399487]
Aigerim S Kamzina, Michelle P DiPalma, Joseph G L Hunter, Andrew G Diamos, Boyd Armer, Tsafrir S Mor, Hugh S Mason. Production of IgG Fusion Proteins Transiently Expressed in Nicotiana benthamiana. Journal of visualized experiments : JoVE. 2021 01; ?(167):. doi: 10.3791/61774. [PMID: 33522504]
Oleg N Oktyabrsky, Ksenia V Bezmaternykh, Galina V Smirnova, Alexey V Tyulenev. Effect of resveratrol and quercetin on the susceptibility of Escherichia coli to antibiotics. World journal of microbiology & biotechnology. 2020 Oct; 36(11):167. doi: 10.1007/s11274-020-02934-y. [PMID: 33025172]
Man Zhu, Shaoguang Li, Hongxing Li, Hui Li, Fan Xia. Employing an Intercalated Redox Reporter in Electrochemical Aptamer-Based Biosensors to Enable Calibration-Free Molecular Measurements in Undiluted Serum. Analytical chemistry. 2020 09; 92(18):12437-12441. doi: 10.1021/acs.analchem.0c02205. [PMID: 32786211]
Hamideh Hamidi, Mahshid Zarrineh, Ali Es-Haghi, Alireza Ghasempour. Rapid and sensitive determination of neomycin and kanamycin in measles, mumps, and rubella vaccine via high-performance liquid chromatography-tandem mass spectrometry using modified super-paramagnetic Fe3O4 nanospheres. Journal of chromatography. A. 2020 Aug; 1625(?):461343. doi: 10.1016/j.chroma.2020.461343. [PMID: 32709308]
Allyson Dailey, Jessica Saha, Fatima Zaidi, Hafsa Abdirahman, Amanda Haymond, Farhang Alem, Ramin Hakami, Robin Couch. VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance. Scientific reports. 2020 07; 10(1):11746. doi: 10.1038/s41598-020-68622-x. [PMID: 32678173]
Zhi-Cheng Wang, Bingyan Wei, Fang-Ning Pei, Teng Yang, Jie Tang, Song Yang, Li-Fang Yu, Cai-Guang Yang, Fan Yang. Capsaicin derivatives with nitrothiophene substituents: Design, synthesis and antibacterial activity against multidrug-resistant S. aureus. European journal of medicinal chemistry. 2020 Jul; 198(?):112352. doi: 10.1016/j.ejmech.2020.112352. [PMID: 32387838]
Jie Yuan, Li Wang, Jinqiu Ren, Jian-Ping Huang, Mingming Yu, Jun Tang, Yijun Yan, Jing Yang, Sheng-Xiong Huang. Antibacterial Pentacyclic Polyketides from a Soil-Derived Streptomyces. Journal of natural products. 2020 06; 83(6):1919-1924. doi: 10.1021/acs.jnatprod.0c00161. [PMID: 32519857]
Jinghua Xue, Hanxiang Li, Ping Wu, Liangxiong Xu, Yunfei Yuan, Xiaoyi Wei. Bioactive Polyhydroxanthones from Penicillium purpurogenum. Journal of natural products. 2020 05; 83(5):1480-1487. doi: 10.1021/acs.jnatprod.9b01071. [PMID: 32293887]
Nazanin Ghafari, Richard Court, Maxwell Tawanda Chirehwa, Lubbe Wiesner, Lucretia Petersen, Gary Maartens, Tawanda Gumbo, Helen McIlleron, Lebogang Ramma. Pharmacokinetics and other risk factors for kanamycin-induced hearing loss in patients with multi-drug resistant tuberculosis. International journal of audiology. 2020 03; 59(3):219-223. doi: 10.1080/14992027.2019.1690170. [PMID: 31739701]
Jinlong Wang, Tingting Lu, Yang Hu, Xueli Wang, Yuangen Wu. A label-free and carbon dots based fluorescent aptasensor for the detection of kanamycin in milk. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2020 Feb; 226(?):117651. doi: 10.1016/j.saa.2019.117651. [PMID: 31629980]
Anindita Mahapatra, Sukanya Sarkar, Subhash Chandra Biswas, Krishnananda Chattopadhyay. An aminoglycoside antibiotic inhibits both lipid-induced and solution-phase fibrillation of α-synuclein in vitro. Chemical communications (Cambridge, England). 2019 Sep; 55(74):11052-11055. doi: 10.1039/c9cc04251b. [PMID: 31453599]
Yi-Ming Wang, Ling-Cong Kong, Lei Liu, Kokou Ayefounin Odah, Shu-Ming Liu, Xiu-Yun Jiang, Hong-Xia Ma. Antibacterial mode of fibrauretine and synergistic effect with kanamycin against multi-drug resistant Escherichia coli. Biotechnology letters. 2019 Sep; 41(8-9):1023-1031. doi: 10.1007/s10529-019-02697-z. [PMID: 31203568]
Diriba Taddese, Tadele Tolosa, Benti Deresa, Matios Lakow, Abebe Olani, Eshetu Shumi. Antibiograms and risk factors of Salmonella isolates from laying hens and eggs in Jimma Town, South Western Ethiopia. BMC research notes. 2019 Aug; 12(1):472. doi: 10.1186/s13104-019-4516-5. [PMID: 31370868]
Workineh Shibeshi, Anandi N Sheth, Addisu Admasu, Alemseged Beyene Berha, Zenebe Negash, Getnet Yimer. Nephrotoxicity and ototoxic symptoms of injectable second-line anti-tubercular drugs among patients treated for MDR-TB in Ethiopia: a retrospective cohort study. BMC pharmacology & toxicology. 2019 05; 20(1):31. doi: 10.1186/s40360-019-0313-y. [PMID: 31122273]
Madher N Alfindee, Yagya P Subedi, Michelle M Grilley, Jon Y Takemoto, Cheng-Wei T Chang. Antifungal Activities of 4″,6″-Disubstituted Amphiphilic Kanamycins. Molecules (Basel, Switzerland). 2019 May; 24(10):. doi: 10.3390/molecules24101882. [PMID: 31100822]
Zhifeng Jia, Meiling He, Chunjie Wang, Aorigele Chen, Xin Zhang, Jin Xu, He Fu, Bo Liu. Nisin reduces uterine inflammation in rats by modulating concentrations of pro- and anti-inflammatory cytokines. American journal of reproductive immunology (New York, N.Y. : 1989). 2019 05; 81(5):e13096. doi: 10.1111/aji.13096. [PMID: 30681748]
Wei Zhang, Shichun Lun, Ling-Ling Liu, Shiqi Xiao, Guanfu Duan, Hendra Gunosewoyo, Fan Yang, Jie Tang, William R Bishai, Li-Fang Yu. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. Journal of medicinal chemistry. 2019 04; 62(7):3575-3589. doi: 10.1021/acs.jmedchem.9b00010. [PMID: 30875203]
Natasha Strydom, Sneha V Gupta, William S Fox, Laura E Via, Hyeeun Bang, Myungsun Lee, Seokyong Eum, TaeSun Shim, Clifton E Barry, Matthew Zimmerman, Véronique Dartois, Radojka M Savic. Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization. PLoS medicine. 2019 04; 16(4):e1002773. doi: 10.1371/journal.pmed.1002773. [PMID: 30939136]
Shengfeng Huang, Ning Gan, Xinyu Zhang, Yongxiang Wu, Yong Shao, Zhengjin Jiang, Qiqin Wang. Portable fluoride-selective electrode as signal transducer for sensitive and selective detection of trace antibiotics in complex samples. Biosensors & bioelectronics. 2019 Mar; 128(?):113-121. doi: 10.1016/j.bios.2018.12.042. [PMID: 30641453]
Weiguo Miao, Jingsheng Wang. Genetic Transformation of Cotton with the Harpin-Encoding Gene hpaXoo of Xanthomonas oryzae pv. oryzae and Evaluation of Resistance Against Verticillium Wilt. Methods in molecular biology (Clifton, N.J.). 2019; 1902(?):257-280. doi: 10.1007/978-1-4939-8952-2_22. [PMID: 30543078]
Yaqin Wang, Yuyao Zhang, Hua Jin, Zhicheng Deng, Zhuan Li, Yanzhen Mai, Guangwei Li, Hong He. A practical random mutagenesis system for Ralstonia solanacearum strains causing bacterial wilt of Pogostemon cablin using Tn5 transposon. World journal of microbiology & biotechnology. 2018 Dec; 35(1):7. doi: 10.1007/s11274-018-2581-x. [PMID: 30565199]
Serena A Mitchell, Fiona Truscott, Rachael Dickman, John Ward, Alethea B Tabor. Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides. Bioorganic & medicinal chemistry. 2018 11; 26(21):5691-5700. doi: 10.1016/j.bmc.2018.10.015. [PMID: 30392955]
Shahrzad Dehghani, Noor Mohammad Danesh, Mohammad Ramezani, Mona Alibolandi, Parirokh Lavaee, Mojgan Nejabat, Khalil Abnous, Seyed Mohammad Taghdisi. A label-free fluorescent aptasensor for detection of kanamycin based on dsDNA-capped mesoporous silica nanoparticles and Rhodamine B. Analytica chimica acta. 2018 Nov; 1030(?):142-147. doi: 10.1016/j.aca.2018.05.003. [PMID: 30032763]
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