NCBI Taxonomy: 58343

Streptomyces canus (ncbi_taxid: 58343)

found 44 associated metabolites at species taxonomy rank level.

Ancestor: Streptomyces aurantiacus group

Child Taxonomies: Streptomyces canus 299MFChir4.1

Acetamiprid

Pesticide4_Acetamiprid_C10H11ClN4_(1E)-N-[(6-chloropyridin-3-yl)methyl]-N-cyano-N-methylethanimidamide

C10H11ClN4 (222.0672196)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals CONFIDENCE standard compound; INTERNAL_ID 2327 CONFIDENCE standard compound; INTERNAL_ID 8448 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2986 Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders[1][2].

   

Thiacloprid

(E)-Thiacloprid

C10H9ClN4S (252.02364239999997)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals CONFIDENCE standard compound; INTERNAL_ID 52; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7159; ORIGINAL_PRECURSOR_SCAN_NO 7155 CONFIDENCE standard compound; INTERNAL_ID 52; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7152; ORIGINAL_PRECURSOR_SCAN_NO 7150 CONFIDENCE standard compound; INTERNAL_ID 52; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7161; ORIGINAL_PRECURSOR_SCAN_NO 7158 CONFIDENCE standard compound; INTERNAL_ID 52; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7190; ORIGINAL_PRECURSOR_SCAN_NO 7188 CONFIDENCE standard compound; INTERNAL_ID 52; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7200; ORIGINAL_PRECURSOR_SCAN_NO 7197 CONFIDENCE standard compound; INTERNAL_ID 52; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7197; ORIGINAL_PRECURSOR_SCAN_NO 7195 INTERNAL_ID 52; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7197; ORIGINAL_PRECURSOR_SCAN_NO 7195 CONFIDENCE standard compound; INTERNAL_ID 3024 CONFIDENCE standard compound; INTERNAL_ID 8424 CONFIDENCE standard compound; INTERNAL_ID 4044 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2954 EAWAG_UCHEM_ID 2954; CONFIDENCE standard compound

   

Actara

Thiamethoxam

C8H10ClN5O3S (291.0192860000001)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals CONFIDENCE standard compound; INTERNAL_ID 1241; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5832; ORIGINAL_PRECURSOR_SCAN_NO 5830 CONFIDENCE standard compound; INTERNAL_ID 1241; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5856; ORIGINAL_PRECURSOR_SCAN_NO 5853 CONFIDENCE standard compound; INTERNAL_ID 1241; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5865; ORIGINAL_PRECURSOR_SCAN_NO 5862 CONFIDENCE standard compound; INTERNAL_ID 1241; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5851; ORIGINAL_PRECURSOR_SCAN_NO 5850 CONFIDENCE standard compound; INTERNAL_ID 1241; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5874; ORIGINAL_PRECURSOR_SCAN_NO 5871 CONFIDENCE standard compound; INTERNAL_ID 1241; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5871; ORIGINAL_PRECURSOR_SCAN_NO 5868 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2941 CONFIDENCE standard compound; INTERNAL_ID 2595 CONFIDENCE standard compound; INTERNAL_ID 8471

   

Kanamycin

(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol

C18H36N4O11 (484.23804659999996)


Kanamycin is only found in individuals that have used or taken this drug. It is an antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components. [PubChem]Aminoglycosides like kanamycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically Kanamycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes. A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07A - Intestinal antiinfectives > A07AA - Antibiotics J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01G - Aminoglycoside antibacterials S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic

   

heliomycin

Resistomycin

C22H16O6 (376.0946836)


C254 - Anti-Infective Agent > C258 - Antibiotic

   

Nitenpyram

Pesticide4_Nitenpyram_C11H15ClN4O2_N-[(6-Chloro-3-pyridinyl)methyl]-N-ethyl-N-methyl-2-nitro-1,1-ethenediamine

C11H15ClN4O2 (270.088348)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals[1][2].

   

Acetamiprid

(1E)-N-((6-Chloro-3-pyridinyl)methyl)-n-cyano-N-methylethanimidamide

C10H11ClN4 (222.0672196)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders[1][2].

   

Thiacloprid

({3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}amino)formonitrile

C10H9ClN4S (252.02364239999997)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals

   

Dinotefuran

Pesticide4_Dinotefuran_C7H14N4O3_Guanidine, N-methyl-N-nitro-N-[(tetrahydro-3-furanyl)methyl]-

C7H14N4O3 (202.1065854)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals CONFIDENCE standard compound; EAWAG_UCHEM_ID 3108 Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors. Target: nAChR, Antiparasitic

   

kanamycin

kanamycin

C18H36N4O11 (484.23804659999996)


A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07A - Intestinal antiinfectives > A07AA - Antibiotics J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01G - Aminoglycoside antibacterials S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic Origin: Microbe, Glycosides, Aminoglycosides KEIO_ID K002; [MS2] KO009014 KEIO_ID K002

   

RESISTOMYCIN

NCGC00160275-01!RESISTOMYCIN

C22H16O6 (376.0946836)


   

Thiamethoxam

Pesticide5_Thiamethoxam_C8H10ClN5O3S_4H-1,3,5-Oxadiazin-4-imine, 3-[(2-chloro-5-thiazolyl)methyl]tetrahydro-5-methyl-N-nitro-, (4E)-

C8H10ClN5O3S (291.0192860000001)


D010575 - Pesticides > D007306 - Insecticides > D000073943 - Neonicotinoids D016573 - Agrochemicals

   

Resistomycin

Resistomycin

C22H16O6 (376.0946836)


Origin: Microbe, Organic chemicals, Polycyclic compounds, Pyrenes

   

(2s)-2-{[(2s)-2-{[(2s)-2-{[(2s,3s)-2-{[(2s)-2-{[(2s)-2-({[(3s,6r,9r,16s,22s,27as)-22-benzyl-1,4,7,11,14,17,20-heptahydroxy-16-isopropyl-6-methyl-3-(2-methylpropyl)-23-oxo-3h,6h,9h,10h,13h,16h,19h,22h,25h,26h,27h,27ah-pyrrolo[2,1-i]1,4,7,10,13,16,19,22-octaazacyclopentacosan-9-yl](hydroxy)methylidene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-methylpentylidene]amino}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1-hydroxy-3-phenylpropylidene]amino}butanedioic acid

(2s)-2-{[(2s)-2-{[(2s)-2-{[(2s,3s)-2-{[(2s)-2-{[(2s)-2-({[(3s,6r,9r,16s,22s,27as)-22-benzyl-1,4,7,11,14,17,20-heptahydroxy-16-isopropyl-6-methyl-3-(2-methylpropyl)-23-oxo-3h,6h,9h,10h,13h,16h,19h,22h,25h,26h,27h,27ah-pyrrolo[2,1-i]1,4,7,10,13,16,19,22-octaazacyclopentacosan-9-yl](hydroxy)methylidene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-methylpentylidene]amino}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1-hydroxy-3-phenylpropylidene]amino}butanedioic acid

C79H102N16O18 (1562.7557632)


   

(3s)-3-{[(3s,7s,13s,16r,22s,28s,31s,34r)-16-(1-aminoethyl)-31-(1-carboxyethyl)-22,28-bis(carboxymethyl)-6,15,18,21,24,27,30,33-octahydroxy-13-isopropyl-4-methyl-2,12-dioxo-1,5,11,14,17,20,23,26,29,32-decaazatricyclo[32.4.0.0⁷,¹¹]octatriaconta-5,14,17,20,23,26,29,32-octaen-3-yl]-c-hydroxycarbonimidoyl}-3-[(1-hydroxy-9-methyldec-3-en-1-ylidene)amino]propanoic acid

(3s)-3-{[(3s,7s,13s,16r,22s,28s,31s,34r)-16-(1-aminoethyl)-31-(1-carboxyethyl)-22,28-bis(carboxymethyl)-6,15,18,21,24,27,30,33-octahydroxy-13-isopropyl-4-methyl-2,12-dioxo-1,5,11,14,17,20,23,26,29,32-decaazatricyclo[32.4.0.0⁷,¹¹]octatriaconta-5,14,17,20,23,26,29,32-octaen-3-yl]-c-hydroxycarbonimidoyl}-3-[(1-hydroxy-9-methyldec-3-en-1-ylidene)amino]propanoic acid

C56H87N13O20 (1261.6190022)


   

3-{[1-({[(1-{[({2-amino-1-[(1-{2-[(1-{1-hydroxy-4-oxo-3h,6h,7h,8h,9h,9ah-pyrido[1,2-a]pyrazin-3-yl}ethyl)-c-hydroxycarbonimidoyl]pyrrolidin-1-yl}-3-methyl-1-oxobutan-2-yl)-c-hydroxycarbonimidoyl]propyl}-c-hydroxycarbonimidoyl)methyl]-c-hydroxycarbonimidoyl}-2-carboxyethyl)-c-hydroxycarbonimidoyl]methyl}-c-hydroxycarbonimidoyl)-2-carboxyethyl]-c-hydroxycarbonimidoyl}-3-({3-carboxy-1-hydroxy-2-[(1-hydroxy-10-methyldodec-3-en-1-ylidene)amino]propylidene}amino)-2-methylpropanoic acid

3-{[1-({[(1-{[({2-amino-1-[(1-{2-[(1-{1-hydroxy-4-oxo-3h,6h,7h,8h,9h,9ah-pyrido[1,2-a]pyrazin-3-yl}ethyl)-c-hydroxycarbonimidoyl]pyrrolidin-1-yl}-3-methyl-1-oxobutan-2-yl)-c-hydroxycarbonimidoyl]propyl}-c-hydroxycarbonimidoyl)methyl]-c-hydroxycarbonimidoyl}-2-carboxyethyl)-c-hydroxycarbonimidoyl]methyl}-c-hydroxycarbonimidoyl)-2-carboxyethyl]-c-hydroxycarbonimidoyl}-3-({3-carboxy-1-hydroxy-2-[(1-hydroxy-10-methyldodec-3-en-1-ylidene)amino]propylidene}amino)-2-methylpropanoic acid

C58H91N13O20 (1289.6503006)


   

(3s)-3-{[(3s,4r,7s,13s,16r,22s,28s,31s,34r)-16-(1-aminoethyl)-31-[(1s)-1-carboxyethyl]-22,28-bis(carboxymethyl)-6,15,18,21,24,27,30,33-octahydroxy-13-isopropyl-4-methyl-2,12-dioxo-1,5,11,14,17,20,23,26,29,32-decaazatricyclo[32.4.0.0⁷,¹¹]octatriaconta-5,14,17,20,23,26,29,32-octaen-3-yl]-c-hydroxycarbonimidoyl}-3-{[(3z)-1-hydroxy-10-methyldodec-3-en-1-ylidene]amino}propanoic acid

(3s)-3-{[(3s,4r,7s,13s,16r,22s,28s,31s,34r)-16-(1-aminoethyl)-31-[(1s)-1-carboxyethyl]-22,28-bis(carboxymethyl)-6,15,18,21,24,27,30,33-octahydroxy-13-isopropyl-4-methyl-2,12-dioxo-1,5,11,14,17,20,23,26,29,32-decaazatricyclo[32.4.0.0⁷,¹¹]octatriaconta-5,14,17,20,23,26,29,32-octaen-3-yl]-c-hydroxycarbonimidoyl}-3-{[(3z)-1-hydroxy-10-methyldodec-3-en-1-ylidene]amino}propanoic acid

C58H91N13O20 (1289.6503006)