PUROMYCIN (BioDeep_00000001635)
natural product PANOMIX_OTCML-2023
代谢物信息卡片
CHEMBL320467
化学式: C22H29N7O5 (471.223)
中文名称: 嘌呤霉素
谱图信息:
最多检出来源 Homo sapiens(otcml) 11.41%
分子结构信息
SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O
InChI: InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1
描述信息
An aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome.
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D009676 - Noxae > D000963 - Antimetabolites
C784 - Protein Synthesis Inhibitor
D000970 - Antineoplastic Agents
KEIO_ID P075; [MS2] KO009213
KEIO_ID P075
同义名列表
4 个代谢物同义名
PUROMYCIN; CHEMBL320467; Puromycin dihydrochloride; Puromycin
数据库引用编号
38 个数据库交叉引用编号
- ChEBI: CHEBI:17939
- KEGG: C01610
- KEGGdrug: D05653
- PubChem: 439530
- Metlin: METLIN43466
- Metlin: METLIN64568
- DrugBank: DB08437
- ChEMBL: CHEMBL469912
- MeSH: Puromycin
- KNApSAcK: C00001507
- CAS: 58-58-2
- CAS: 53-79-2
- MoNA: Bruker_HCD_library001274
- MoNA: Bruker_HCD_library001275
- MoNA: MoNA041636
- MoNA: KO003831
- MoNA: KO009215
- MoNA: KO009214
- MoNA: KO001689
- MoNA: KO001686
- MoNA: KO009213
- MoNA: KO003829
- MoNA: KO001687
- MoNA: KO003830
- MoNA: KO003832
- MoNA: KO001690
- MoNA: KO003828
- MoNA: KO001688
- PMhub: MS000000891
- MetaboLights: MTBLC17939
- PubChem: 4763
- PDB-CCD: PUY
- 3DMET: B01469
- NIKKAJI: J2.310H
- KEGG: C11618
- PubChem: 13783
- KNApSAcK: 8642
- KNApSAcK: 17939
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 132473 - Streptomyces alboniger:
- 68174 - Streptomyces anthocyanicus: 10.1016/S0014-5793(97)01564-0
- 1916 - Streptomyces lividans: 10.1016/S0014-5793(97)01564-0
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bing Zhang, Shiying Huang, Zhuoting Liu, Xinhui Liu, Zilan Jiang, Jianping Chen, Youjia Zeng. Investigation of the Metabolism of Astragaloside IV in a Puromycin-Damaged Rat Model by UPLC-Q-TOF-MS/MS Analysis.
Planta medica.
2023 Nov; ?(?):. doi:
10.1055/a-2186-3182. [PMID: 37931776] - Ming Lyu, Yongsen Sun, Nana Yan, Qiang Chen, Xin Wang, Zehui Wei, Zhiying Zhang, Kun Xu. Efficient CRISPR/Cas9-mediated gene editing in mammalian cells by the novel selectable traffic light reporters.
International journal of biological macromolecules.
2023 Jul; 243(?):124926. doi:
10.1016/j.ijbiomac.2023.124926. [PMID: 37217056] - Baowei Ji, Junchao Liu, Yanli Ma, Ye Yin, Hong Xu, Qian Shen, Jian Yu. Minnelide Markedly Reduces Proteinuria in Mice with Adriamycin Nephropathy by Protecting Against Podocyte Injury.
Applied biochemistry and biotechnology.
2023 Mar; ?(?):. doi:
10.1007/s12010-023-04333-z. [PMID: 37000351] - Chen Zhang, Kah Yean Lum, Aya C Taki, Robin B Gasser, Joseph J Byrne, Luis J Montaner, Ian Tietjen, Vicky M Avery, Rohan A Davis. Using a Bioactive Eremophila-Derived Serrulatane Scaffold to Generate a Unique Carbamate Library for Anti-infective Evaluations.
Journal of natural products.
2023 03; 86(3):557-565. doi:
10.1021/acs.jnatprod.2c01041. [PMID: 36799121] - Saaya Hatakeyama, Akihiro Tojo, Hiroshi Satonaka, Nami O Yamada, Takao Senda, Toshihiko Ishimitsu. Decreased Podocyte Vesicle Transcytosis and Albuminuria in APC C-Terminal Deficiency Mice with Puromycin-Induced Nephrotic Syndrome.
International journal of molecular sciences.
2021 Dec; 22(24):. doi:
10.3390/ijms222413412. [PMID: 34948207] - Yong Huang, Yaqian Huang, Yehua Zhou, Jie Cheng, Chanjun Wan, Maohong Wang, Chiheng Pi, Guoqing Wu, Weiguo Song. Shensu IV prevents glomerular podocyte injury in nephrotic rats via promoting lncRNA H19/DIRAS3-mediated autophagy.
Bioscience reports.
2021 05; 41(5):. doi:
10.1042/bsr20203362. [PMID: 33881140] - Rémi Roumanille, Barbara Vernus, Thomas Brioche, Vincent Descossy, Christophe Tran Van Ba, Sarah Campredon, Antony G Philippe, Pierre Delobel, Christelle Bertrand-Gaday, Angèle Chopard, Anne Bonnieu, Guillaume Py, Pascale Fança-Berthon. Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis and mechanical power in rats.
Journal of the International Society of Sports Nutrition.
2020 Nov; 17(1):58. doi:
10.1186/s12970-020-00390-5. [PMID: 33198764] - Gasper Maeda, Joan J E Munissi, Sofia Lindblad, Sandra Duffy, Jerry Pelletier, Vicky M Avery, Stephen S Nyandoro, Máté Erdélyi. A Meroisoprenoid, Heptenolides, and C-Benzylated Flavonoids from Sphaerocoryne gracilis ssp. gracilis.
Journal of natural products.
2020 02; 83(2):316-322. doi:
10.1021/acs.jnatprod.9b00721. [PMID: 32067457] - Luke P Robertson, Leonardo Lucantoni, Sandra Duffy, Vicky M Avery, Anthony R Carroll. Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens.
Journal of natural products.
2019 04; 82(4):1019-1023. doi:
10.1021/acs.jnatprod.8b00956. [PMID: 30865443] - Takumi Kagawa, Tomáš Zárybnický, Takanao Omi, Yuji Shirai, Shinya Toyokuni, Shingo Oda, Tsuyoshi Yokoi. A scrutiny of circulating microRNA biomarkers for drug-induced tubular and glomerular injury in rats.
Toxicology.
2019 03; 415(?):26-36. doi:
10.1016/j.tox.2019.01.011. [PMID: 30682439] - Vitalina Gryshkova, Mabel Cotter, Portia McGhan, Jana Obajdin, Renaud Fleurance, Andre Nogueira da Costa. Phosphoprotein expression profiles in rat kidney injury: Source for potential mechanistic biomarkers.
Journal of cellular and molecular medicine.
2019 03; 23(3):2251-2255. doi:
10.1111/jcmm.14103. [PMID: 30636369] - Jana Obajdin, Mabel Cotter, Sara Snelling, Sarah Dremier, Pierrette De Ron, Renaud Fleurance, Jean-Pierre Valentin, André Nogueira da Costa, Vitalina Gryshkova. Fatty-Acid Binding Protein 4 (FABP4) as a Potential Preclinical Biomarker of Drug-Induced Kidney Injury.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 Dec; 166(2):441-450. doi:
10.1093/toxsci/kfy204. [PMID: 30215792] - Stéphanie F Glineur, Etienne Hanon, Sarah Dremier, Sara Snelling, Caroline Berteau, Pierrette De Ron, André Nogueira da Costa. Assessment of a Urinary Kidney MicroRNA Panel as Potential Nephron Segment-Specific Biomarkers of Subacute Renal Toxicity in Preclinical Rat Models.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 12; 166(2):409-419. doi:
10.1093/toxsci/kfy213. [PMID: 30169741] - Sarath P D Senadeera, Leonardo Lucantoni, Sandra Duffy, Vicky M Avery, Anthony R Carroll. Antiplasmodial β-Triketone-Flavanone Hybrids from the Flowers of the Australian Tree Corymbia torelliana.
Journal of natural products.
2018 07; 81(7):1588-1597. doi:
10.1021/acs.jnatprod.8b00154. [PMID: 29969262] - Sebastien Andrew Rider, Finnius Austin Bruton, Richard George Collins, Bryan Ronald Conway, John James Mullins. The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics.
Zebrafish.
2018 06; 15(3):234-242. doi:
10.1089/zeb.2017.1527. [PMID: 29480793] - Rohitesh Kumar, Sandra Duffy, Vicky M Avery, Anthony R Carroll, Rohan A Davis. Microthecaline A, a Quinoline Serrulatane Alkaloid from the Roots of the Australian Desert Plant Eremophila microtheca.
Journal of natural products.
2018 04; 81(4):1079-1083. doi:
10.1021/acs.jnatprod.7b00992. [PMID: 29533611] - Michelle L DeBoer, Krishona M Martinson, Mary S Pampusch, Abigail M Hansen, Scott M Wells, Christie Ward, Marcia Hathaway. Cultured equine satellite cells as a model system to assess leucine stimulated protein synthesis in horse muscle.
Journal of animal science.
2018 Feb; 96(1):143-153. doi:
10.1093/jas/skx028. [PMID: 29444251] - Luke P Robertson, Sandra Duffy, Yun Wang, Dongdong Wang, Vicky M Avery, Anthony R Carroll. Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana.
Journal of natural products.
2017 12; 80(12):3211-3217. doi:
10.1021/acs.jnatprod.7b00587. [PMID: 29236492] - Hannah Crossland, Kenneth Smith, Philip J Atherton, Daniel J Wilkinson. A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: A proof-of-concept study.
Biochemical and biophysical research communications.
2017 12; 494(3-4):608-614. doi:
10.1016/j.bbrc.2017.10.085. [PMID: 29054406] - Olivier Delézay, Zhiguo He, Sophie Hodin, Moin A Saleem, Patrick Mismetti, Nathalie Perek, Xavier Delavenne. Glomerular filtration drug injury: In vitro evaluation of functional and morphological podocyte perturbations.
Experimental cell research.
2017 12; 361(2):300-307. doi:
10.1016/j.yexcr.2017.10.031. [PMID: 29107066] - Ryan A West, Oran G O'Doherty, Trevor Askwith, John Atack, Paul Beswick, Jamie Laverick, Michael Paradowski, Lewis E Pennicott, Srinivasa P S Rao, Gareth Williams, Simon E Ward. African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase.
European journal of medicinal chemistry.
2017 Dec; 141(?):676-689. doi:
10.1016/j.ejmech.2017.09.067. [PMID: 29107420] - Rohitesh Kumar, Sandra Duffy, Vicky M Avery, Rohan A Davis. Synthesis of antimalarial amide analogues based on the plant serrulatane diterpenoid 3,7,8-trihydroxyserrulat-14-en-19-oic acid.
Bioorganic & medicinal chemistry letters.
2017 09; 27(17):4091-4095. doi:
10.1016/j.bmcl.2017.07.039. [PMID: 28774427] - Sarath P D Senadeera, Sandra Duffy, Vicky M Avery, Anthony R Carroll. Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana.
Bioorganic & medicinal chemistry letters.
2017 06; 27(11):2602-2607. doi:
10.1016/j.bmcl.2017.03.065. [PMID: 28400231] - Sandra Bodeau, Chloé Sauzay, Rémy Nyga, Christophe Louandre, Véronique Descamps, Catherine François, Corinne Godin, Gabriel Choukroun, Antoine Galmiche. Targeting the Unfolded Protein Response as a Potential Therapeutic Strategy in Renal Carcinoma Cells Exposed to Cyclosporine A.
Anticancer research.
2017 03; 37(3):1049-1057. doi:
10.21873/anticanres.11416. [PMID: 28314264] - Stephen S Nyandoro, Joan J E Munissi, Amra Gruhonjic, Sandra Duffy, Fangfang Pan, Rakesh Puttreddy, John P Holleran, Paul A Fitzpatrick, Jerry Pelletier, Vicky M Avery, Kari Rissanen, Máté Erdélyi. Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves.
Journal of natural products.
2017 01; 80(1):114-125. doi:
10.1021/acs.jnatprod.6b00759. [PMID: 28001067] - Yoshikazu Muroya, Osamu Ito. Effect of clofibrate on fatty acid metabolism in the kidney of puromycin-induced nephrotic rats.
Clinical and experimental nephrology.
2016 Dec; 20(6):862-870. doi:
10.1007/s10157-016-1253-0. [PMID: 26949064] - Fraser J Scott, Abedawn I Khalaf, Sandra Duffy, Vicky M Avery, Colin J Suckling. Selective anti-malarial minor groove binders.
Bioorganic & medicinal chemistry letters.
2016 07; 26(14):3326-3329. doi:
10.1016/j.bmcl.2016.05.039. [PMID: 27212070] - Zhe Lyu, Rachit Jain, Peyton Smith, Travis Fetchko, Yajun Yan, William B Whitman. Engineering the Autotroph Methanococcus maripaludis for Geraniol Production.
ACS synthetic biology.
2016 07; 5(7):577-81. doi:
10.1021/acssynbio.5b00267. [PMID: 26886063] - Melanie Adler, Susanne Ramm, Marc Hafner, Jeremy L Muhlich, Esther Maria Gottwald, Elijah Weber, Alenka Jaklic, Amrendra Kumar Ajay, Daniel Svoboda, Scott Auerbach, Edward J Kelly, Jonathan Himmelfarb, Vishal S Vaidya. A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro.
Journal of the American Society of Nephrology : JASN.
2016 Apr; 27(4):1015-28. doi:
10.1681/asn.2015010060. [PMID: 26260164] - Tsegaye Deyou, Ivan Gumula, Fangfang Pang, Amra Gruhonjic, Michael Mumo, John Holleran, Sandra Duffy, Paul A Fitzpatrick, Matthias Heydenreich, Göran Landberg, Solomon Derese, Vicky Avery, Kari Rissanen, Máté Erdélyi, Abiy Yenesew. Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.
Journal of natural products.
2015 Dec; 78(12):2932-9. doi:
10.1021/acs.jnatprod.5b00581. [PMID: 26651537] - Edgar Maquigussa, Carine P Arnoni, Luciana G Pereira, Mirian A Boim. Calcitriol ameliorates renal damage in a pre-established proteinuria model.
Molecular medicine reports.
2015 Jul; 12(1):1009-15. doi:
10.3892/mmr.2015.3555. [PMID: 25823676] - De-shu Dai, Xiang Liu, Yang Yang, Xiao-mei Luo, Ren-xian Tang, Zhong-cheng Yin, Hong-qi Ren. Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury.
American journal of nephrology.
2015; 42(3):216-27. doi:
10.1159/000440851. [PMID: 26439819] - Ellen T McCarthy, Jianping Zhou, Ryan Eckert, David Genochio, Rishi Sharma, Olurinde Oni, Alok De, Tarak Srivastava, Ram Sharma, Virginia J Savin, Mukut Sharma. Ethanol at low concentrations protects glomerular podocytes through alcohol dehydrogenase and 20-HETE.
Prostaglandins & other lipid mediators.
2015 Jan; 116-117(?):88-98. doi:
10.1016/j.prostaglandins.2014.10.006. [PMID: 25447342] - Christiane Sippl, Ludwig F Zeilbeck, Rudolf Fuchshofer, Ernst R Tamm. Optineurin associates with the podocyte Golgi complex to maintain its structure.
Cell and tissue research.
2014 Nov; 358(2):567-83. doi:
10.1007/s00441-014-1968-8. [PMID: 25096716] - Micaela Cerletti, María J Martínez, María I Giménez, Diego E Sastre, Roberto A Paggi, Rosana E De Castro. The LonB protease controls membrane lipids composition and is essential for viability in the extremophilic haloarchaeon Haloferax volcanii.
Environmental microbiology.
2014 Jun; 16(6):1779-92. doi:
10.1111/1462-2920.12385. [PMID: 24428705] - Yui Yamashita, Yoshitomo Kadokura, Naoyuki Sotta, Toru Fujiwara, Ichigaku Takigawa, Akiko Satake, Hitoshi Onouchi, Satoshi Naito. Ribosomes in a stacked array: elucidation of the step in translation elongation at which they are stalled during S-adenosyl-L-methionine-induced translation arrest of CGS1 mRNA.
The Journal of biological chemistry.
2014 May; 289(18):12693-704. doi:
10.1074/jbc.m113.526616. [PMID: 24652291] - V N Karavana, H Gakiopoulou, E A Lianos. Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study.
European journal of histochemistry : EJH.
2014 Apr; 58(2):2308. doi:
10.4081/ejh.2014.2308. [PMID: 24998921] - Evren U Azeloglu, Simon V Hardy, Narat John Eungdamrong, Yibang Chen, Gomathi Jayaraman, Peter Y Chuang, Wei Fang, Huabao Xiong, Susana R Neves, Mohit R Jain, Hong Li, Avi Ma'ayan, Ronald E Gordon, John Cijiang He, Ravi Iyengar. Interconnected network motifs control podocyte morphology and kidney function.
Science signaling.
2014 Feb; 7(311):ra12. doi:
10.1126/scisignal.2004621. [PMID: 24497609] - Javier P Martínez, Gemma Pérez-Vilaró, Yazh Muthukumar, Nicoletta Scheller, Tatjana Hirsch, Randi Diestel, Heinrich Steinmetz, Rolf Jansen, Ronald Frank, Florenz Sasse, Andreas Meyerhans, Juana Díez. Screening of small molecules affecting mammalian P-body assembly uncovers links with diverse intracellular processes and organelle physiology.
RNA biology.
2013 Nov; 10(11):1661-9. doi:
10.4161/rna.26851. [PMID: 24418890] - Kapil Chaudhary, Daniel T Kleven, Tracy L McGaha, Michael P Madaio. A human monoclonal antibody against the collagen type IV α3NC1 domain is a non-invasive optical biomarker for glomerular diseases.
Kidney international.
2013 Aug; 84(2):403-8. doi:
10.1038/ki.2013.99. [PMID: 23515049] - Daryl L Richie, Katherine V Thompson, Christian Studer, Vivian C Prindle, Thomas Aust, Ralph Riedl, David Estoppey, Jianshi Tao, Jessica A Sexton, Thomas Zabawa, Joseph Drumm, Simona Cotesta, Jürg Eichenberger, Sven Schuierer, Nicole Hartmann, N Rao Movva, John A Tallarico, Neil S Ryder, Dominic Hoepfner. Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents.
Antimicrobial agents and chemotherapy.
2013 May; 57(5):2272-80. doi:
10.1128/aac.01809-12. [PMID: 23478965] - Takahiro Ishizawa, Takashi Kawakami, Patrick C Reid, Hiroshi Murakami. TRAP display: a high-speed selection method for the generation of functional polypeptides.
Journal of the American Chemical Society.
2013 Apr; 135(14):5433-40. doi:
10.1021/ja312579u. [PMID: 23506421] - Damir Simic, Frank Simutis, Catherine Euler, Christina Thurby, W Mike Peden, R Todd Bunch, Gary Pilcher, Thomas Sanderson, Terry Van Vleet. Determination of relative Notch1 and gamma-secretase-related gene expression in puromycin-treated microdissected rat kidneys.
Gene expression.
2013; 16(1):39-47. doi:
10.3727/105221613x13806435102312. [PMID: 24397211] - Jiyoung Moon, Seung-Min Lee, Hyun Ju Do, Yoonsu Cho, Ji Hyung Chung, Min-Jeong Shin. Quercetin up-regulates LDL receptor expression in HepG2 cells.
Phytotherapy research : PTR.
2012 Nov; 26(11):1688-94. doi:
10.1002/ptr.4646. [PMID: 22388943] - Tobias Christian Fuchs, Katharina Frick, Barbara Emde, Stephanie Czasch, Friedrich von Landenberg, Philip Hewitt. Evaluation of novel acute urinary rat kidney toxicity biomarker for subacute toxicity studies in preclinical trials.
Toxicologic pathology.
2012 Oct; 40(7):1031-48. doi:
10.1177/0192623312444618. [PMID: 22581810] - Shoudong Ye, Li Tan, Rongqing Yang, Bo Fang, Su Qu, Eric N Schulze, Houyan Song, Qilong Ying, Ping Li. Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
PloS one.
2012; 7(4):e35892. doi:
10.1371/journal.pone.0035892. [PMID: 22540008] - Shuangxin Liu, Wei Shi, Houqin Xiao, Xinling Liang, Chunyu Deng, Zhiming Ye, Ping Mei, Suxia Wang, Xiaoying Liu, Zhixin Shan, Yongzheng Liang, Bin Zhang, Wenjian Wang, Yanhui Liu, Lixia Xu, Yunfeng Xia, Jianchao Ma, Zhilian Li. Receptor activator of NF-kappaB and podocytes: towards a function of a novel receptor-ligand pair in the survival response of podocyte injury.
PloS one.
2012; 7(7):e41331. doi:
10.1371/journal.pone.0041331. [PMID: 22848465] - Meike J Ochs, Bernd L Sorg, Laura Pufahl, Manuel Grez, Beatrix Suess, Dieter Steinhilber. Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay.
PloS one.
2012; 7(2):e31363. doi:
10.1371/journal.pone.0031363. [PMID: 22363630] - Satoshi Kinugasa, Akihiro Tojo, Tatsuo Sakai, Harukuni Tsumura, Masafumi Takahashi, Yasunobu Hirata, Toshiro Fujita. Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase.
Kidney international.
2011 Dec; 80(12):1328-38. doi:
10.1038/ki.2011.282. [PMID: 21849973] - Daisuke Sasaki, Atsushi Yamada, Hitomi Umeno, Hiroshi Kurihara, Shunji Nakatsuji, Shiro Fujihira, Kenjiro Tsubota, Mihoko Ono, Akira Moriguchi, Kouji Watanabe, Jiro Seki. Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2011 Nov; 16(7):553-66. doi:
10.3109/1354750x.2011.613123. [PMID: 21955166] - Nosratola D Vaziri, Pavan Gollapudi, Seungyeup Han, Guity Farahmand, Jun Yuan, Ardeshir Rahimi, Hamid Moradi. Nephrotic syndrome causes upregulation of HDL endocytic receptor and PDZK-1-dependent downregulation of HDL docking receptor.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2011 Oct; 26(10):3118-23. doi:
10.1093/ndt/gfr136. [PMID: 21459782] - Craig A Goodman, Danielle M Mabrey, John W Frey, Man Hing Miu, Enrico K Schmidt, Philippe Pierre, Troy A Hornberger. Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2011 Mar; 25(3):1028-39. doi:
10.1096/fj.10-168799. [PMID: 21148113] - Catherine Meyer-Schwesinger, Claudia Lange, Verena Bröcker, Putri Andina Agustian, Putri Andina Agustian, Ulrich Lehmann, Annette Raabe, Martina Brinkmeyer, Eiji Kobayashi, Mario Schiffer, Guntram Büsche, Hans H Kreipe, Friedrich Thaiss, Jan U Becker. Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats.
The American journal of pathology.
2011 Feb; 178(2):494-9. doi:
10.1016/j.ajpath.2010.10.024. [PMID: 21281782] - Rafaela F Alponti, Paulo F Silveira. Neutral aminopeptidase and dipeptidyl peptidase IV activities in plasma of monosodium glutamate obese and food-deprived rats.
Obesity (Silver Spring, Md.).
2010 Jul; 18(7):1312-7. doi:
10.1038/oby.2009.378. [PMID: 19876009] - Nadav Bar, Rivka Dikstein. miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics.
PloS one.
2010 May; 5(5):e10859. doi:
10.1371/journal.pone.0010859. [PMID: 20523723] - Dirk Theile, Bianca Staffen, Johanna Weiss. ATP-binding cassette transporters as pitfalls in selection of transgenic cells.
Analytical biochemistry.
2010 Apr; 399(2):246-50. doi:
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Blood.
2010 Mar; 115(10):2065-72. doi:
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American journal of physiology. Renal physiology.
2009 Oct; 297(4):F1006-16. doi:
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PloS one.
2009 Sep; 4(9):e7068. doi:
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Bioorganic & medicinal chemistry.
2009 May; 17(9):3443-55. doi:
10.1016/j.bmc.2009.03.028. [PMID: 19356937] - Maryam Mirzaei, Yan Xu, Cynthia B Elias, Satya Prakash. Nonviral production of human interleukin-7 in spodoptera frugiperda insect cells as a soluble recombinant protein.
Journal of biomedicine & biotechnology.
2009; 2009(?):637942. doi:
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American journal of physiology. Renal physiology.
2008 Nov; 295(5):F1519-27. doi:
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Journal of natural products.
2008 Jun; 71(6):1049-51. doi:
10.1021/np070458f. [PMID: 18512984] - Guozheng Cong, Jianhua Zhou, Shandian Gao, Junzheng Du, Junjun Shao, Tong Lin, Huiyun Chang, Qingge Xie. [Construction of recombinant retroviral vector carrying Lab gene of foot-and-mouth disease virus and its expression in bovine kidney (MDBK) cells].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology.
2008 May; 24(5):740-5. doi:
10.1016/s1872-2075(08)60038-2. [PMID: 18724691] - Law Chung Hiong, Kiew Lik Voon, Nor Azizan Abdullah, Munavvar A Sattar, Nazarina Abdul Rahman, Abdul Hye Khan, Edward James Johns. Effect of TGF-beta1 antisense oligodeoxynucleotide on renal function in chronic renal failure rats.
Acta pharmacologica Sinica.
2008 Apr; 29(4):451-7. doi:
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Journal of pineal research.
2008 Apr; 44(3):316-25. doi:
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Bioorganic & medicinal chemistry letters.
2007 Aug; 17(16):4654-6. doi:
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Canadian journal of physiology and pharmacology.
2007 May; 85(5):502-6. doi:
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Journal of virology.
2007 Mar; 81(6):2584-91. doi:
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Experimental cell research.
2007 Jan; 313(1):38-52. doi:
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American journal of physiology. Renal physiology.
2007 Jan; 292(1):F192-6. doi:
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Clinical nephrology.
2006 Dec; 66(6):405-10. doi:
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RNA (New York, N.Y.).
2006 Sep; 12(9):1683-92. doi:
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RNA (New York, N.Y.).
2006 May; 12(5):717-25. doi:
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Molecular biology of the cell.
2006 Apr; 17(4):1664-75. doi:
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Biochimica et biophysica acta.
2006 Mar; 1763(3):296-304. doi:
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American journal of physiology. Regulatory, integrative and comparative physiology.
2006 Jan; 290(1):R66-72. doi:
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Journal of the American Society of Nephrology : JASN.
2005 Dec; 16(12):3642-50. doi:
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The Journal of biological chemistry.
2005 Jul; 280(26):24396-403. doi:
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The Journal of pharmacology and experimental therapeutics.
2005 Jun; 313(3):943-51. doi:
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American journal of physiology. Renal physiology.
2005 Apr; 288(4):F748-56. doi:
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Kidney international.
2005 Feb; 67(2):514-23. doi:
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Nihon rinsho. Japanese journal of clinical medicine.
2004 Oct; 62(10):1770-2. doi:
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The Journal of biological chemistry.
2004 Aug; 279(33):34827-32. doi:
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Journal of fish diseases.
2004 May; 27(5):277-85. doi:
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Cell calcium.
2004 Apr; 35(4):307-15. doi:
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Radiation research.
2004 Apr; 161(4):418-29. doi:
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Environmental health perspectives.
2004 Mar; 112(4):460-4. doi:
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Journal of virology.
2004 Mar; 78(6):2819-30. doi:
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Environmental health perspectives.
2004 Mar; 112(4):465-79. doi:
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Journal of neurochemistry.
2004 Jan; 88(1):23-31. doi:
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Journal of nephrology.
2003 Mar; 16(2):210-8. doi:
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Kidney international.
2003 Jan; 63(1):107-12. doi:
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European journal of histochemistry : EJH.
2003; 47(4):299-308. doi:
10.4081/840. [PMID: 14706925] - Koshi Mori, Hidemi Shimizu, Akihiro Konno, Toshihiko Iwanaga. Immunohistochemical localization of napsin and its potential role in protein catabolism in renal proximal tubules.
Archives of histology and cytology.
2002 Oct; 65(4):359-68. doi:
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Kidney international.
2002 Sep; 62(3):868-76. doi:
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Kidney international.
2002 Aug; 62(2):496-506. doi:
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2002 Aug; 22(8):613-7. doi:
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Journal of molecular recognition : JMR.
2002 May; 15(3):126-34. doi:
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