Nonadecanoic acid (BioDeep_00000011246)

 

Secondary id: BioDeep_00000864474

human metabolite PANOMIX_OTCML-2023 Endogenous PANOMIX LipidSearch BioNovoGene_Lab2019 natural product


代谢物信息卡片


nonadecanoic acid

化学式: C19H38O2 (298.2872)
中文名称: 十九烷酸, 正碳十九酸, 十九酸
谱图信息: 最多检出来源 Homo sapiens(feces) 25.16%

分子结构信息

SMILES: C(CCCCCCCCC)CCCCCCCCC(=O)O
InChI: InChI=1S/C19H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21/h2-18H2,1H3,(H,20,21)

描述信息

Nonadecanoic acid, also known as n-nonadecanoic acid or nonadecylic acid or C19:0, belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms, with nonadecanoic acid (its ester is called nonadecanoate) having 19 carbon atoms. Nonadecanoic acid is a very hydrophobic molecule, practically insoluble (in water). It is a solid with a melting point of 69.4°C. It can be found in bacteria, plants, and animals (including animal milk) (Nature 176:882; PMID: 14168161). It is secreted by termites (Rhinotermes marginalis) as part of its defence mechanism (Comp. Biochem. Physiol. B 71:731).
Nonadecanoic acid is a C19 straight-chain fatty acid of plant or bacterial origin. An intermediate in the biodegradation of n-icosane, it has been shown to inhibit cancer growth. It has a role as a fungal metabolite. It is a straight-chain saturated fatty acid and a long-chain fatty acid. It is a conjugate acid of a nonadecanoate.
Nonadecanoic acid is a natural product found in Staphisagria macrosperma, Malva sylvestris, and other organisms with data available.
An odd-numbered long chain fatty acid, likely derived from bacterial or plant sources. Nonadecanoic acid has been found in ox fats and vegetable oils. It is also used by certain insects as a phermone. [HMDB].
A C19 straight-chain fatty acid of plant or bacterial origin. An intermediate in the biodegradation of n-icosane, it has been shown to inhibit cancer growth.
Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence[1].
Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence[1].

同义名列表

23 个代谢物同义名

9-(2-CARBOXYPHENYL)-3,6-BIS(DIMETHYLAMINO)XANTHYLIUMPERCHLORATE; Nonadecanoic acid, analytical standard; Nonadecanoic acid, >=98.0\\% (GC); Nonadecanoic acid, >=98\\% (GC); nonadecanoic-d37 acid; nonadecansäure; n-Nonadecanoic acid; n-Nonadecylic acid; Nonadecanoic acid; nonadecanoicacid; Nonadecylic acid; UNII-H6M3VYC62P; n-Nonadecanoate; n-Nonadecylate; Nonadecanoate; Nonadecylate; H6M3VYC62P; AI3-36442; FA(19:0); FA 19:0; 19:00; C19:0; EW8



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

172 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ANXA5, CASP3, CAT, HSD3B2, PER1
Peripheral membrane protein 6 ANXA5, CYP11A1, CYP1B1, CYP21A2, MBP, MYO10
Endoplasmic reticulum membrane 6 CERS4, CYP17A1, CYP19A1, CYP1B1, CYP21A2, HSD3B2
Mitochondrion membrane 1 CYP11A1
Nucleus 5 CASP3, CERS4, MBP, MPO, PER1
cytosol 6 ANXA5, CASP3, CAT, MBP, MYO10, PER1
mitochondrial membrane 1 HSD3B2
nucleoplasm 3 CASP3, MPO, PER1
Cell membrane 1 TNF
Cytoplasmic side 1 MBP
lamellipodium 1 MYO10
Multi-pass membrane protein 2 CERS4, CYP19A1
Synapse 1 MBP
cell cortex 1 MYO10
cell surface 2 MBP, TNF
glutamatergic synapse 1 CASP3
Golgi apparatus 1 ATRN
mitochondrial inner membrane 2 CYP11A1, HSD3B2
neuronal cell body 5 CASP3, CYP17A1, MBP, MYO10, TNF
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 MYO10
Lysosome 1 MPO
plasma membrane 5 ATRN, LCT, MBP, MYO10, TNF
Membrane 7 ANXA5, CAT, CYP11A1, CYP19A1, CYP1B1, CYP21A2, HSD3B2
axon 1 CYP17A1
extracellular exosome 5 ANXA5, ATRN, CAT, MBP, MPO
endoplasmic reticulum 3 CYP17A1, CYP19A1, HSD3B2
extracellular space 5 ATRN, GH2, IL6, MPO, TNF
mitochondrion 3 CAT, CYP11A1, CYP1B1
protein-containing complex 2 CAT, MBP
intracellular membrane-bounded organelle 4 CAT, CYP1B1, HSD3B2, MPO
Microsome membrane 4 CYP17A1, CYP19A1, CYP1B1, CYP21A2
filopodium 1 MYO10
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 ATRN, LCT
Secreted 2 GH2, IL6
extracellular region 7 ANXA5, CAT, GH2, IL6, MBP, MPO, TNF
Single-pass membrane protein 2 CYP21A2, HSD3B2
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 2 CAT, CYP11A1
external side of plasma membrane 2 ANXA5, TNF
nucleolus 2 HSD3B2, MYO10
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 LCT
Cell projection, filopodium tip 1 MYO10
Cell projection, lamellipodium 1 MYO10
filopodium tip 1 MYO10
Mitochondrion inner membrane 1 CYP11A1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 MYO10
focal adhesion 2 ANXA5, CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
mitochondrial intermembrane space 1 HSD3B2
collagen-containing extracellular matrix 2 ANXA5, MBP
secretory granule 1 MPO
Cell projection, ruffle 1 MYO10
ruffle 1 MYO10
Zymogen granule membrane 1 ANXA5
neuron projection 1 MYO10
phagocytic cup 1 TNF
cell periphery 1 MBP
[Isoform 3]: Nucleus 1 MBP
Cytoplasm, cell cortex 1 MYO10
[Isoform 3]: Secreted 1 ATRN
intercellular bridge 1 HSD3B2
endosome lumen 1 GH2
myosin complex 1 MYO10
Smooth endoplasmic reticulum membrane 1 HSD3B2
myelin sheath 1 MBP
filopodium membrane 1 MYO10
azurophil granule 1 MPO
ficolin-1-rich granule lumen 2 CAT, MBP
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 IL6
transport vesicle 1 MBP
azurophil granule lumen 1 MPO
vesicle membrane 1 ANXA5
phagocytic vesicle lumen 1 MPO
external side of apical plasma membrane 1 LCT
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 ATRN
Cell projection, filopodium membrane 1 MYO10
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
compact myelin 1 MBP
internode region of axon 1 MBP
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
endothelial microparticle 1 ANXA5
[Bone marrow proteoglycan]: Secreted 1 MBP
Myelin membrane 1 MBP
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Hiroshi Nakahashi, Yuka Nishino, Hiroki Nakagawa, Nobuyuki Hara, Atsushi Usami, Mitsuo Miyazawa. Evaluation of the Key Odorants in Volatile Oils from Tubers of Apios americana Medikus. Journal of oleo science. 2015; 64(11):1235-42. doi: 10.5650/jos.ess15132. [PMID: 26521814]
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  • Céline Dejoye, Maryline Abert Vian, Guy Lumia, Christian Bouscarle, Frederic Charton, Farid Chemat. Combined extraction processes of lipid from Chlorella vulgaris microalgae: microwave prior to supercritical carbon dioxide extraction. International journal of molecular sciences. 2011; 12(12):9332-41. doi: 10.3390/ijms12129332. [PMID: 22272135]
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