Chloroacetyl chloride (BioDeep_00000010194)

 

Secondary id: BioDeep_00001873648

human metabolite


代谢物信息卡片


Monochloroacetyl chloride

化学式: C2H2Cl2O (111.9483)
中文名称: 氯乙酰氯
谱图信息: 最多检出来源 Homo sapiens(blood) 5.06%

分子结构信息

SMILES: C(C(=O)Cl)Cl
InChI: InChI=1S/C2H2Cl2O/c3-1-2(4)5/h1H2

描述信息

Chloroacetyl chloride is a chlorinated acyl chloride. It is a bifunctional compound, making it a useful building block chemical. (Wikipedia)

同义名列表

4 个代谢物同义名

Monochloroacetyl chloride; 2-chloroacetyl chloride; CHLOROACETYL CHLORIDE; Chloroacetyl chloride



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 CDK5, CYP2E1, DHFR, GRIN1, HMGB1, HPGDS, JAK2, MSMP
Peripheral membrane protein 4 CYP1B1, CYP2E1, HMGB1, JAK2
Endosome membrane 1 SLC6A4
Endoplasmic reticulum membrane 4 CYP1B1, CYP2E1, GRIN1, GRIN2A
Nucleus 5 ACR, CDK5, HMGB1, JAK2, PRAC1
cytosol 6 CDK5, DCTN5, DHFR, HPGDS, JAK2, PRAC1
dendrite 2 CDK5, GRIN1
centrosome 1 DCTN5
nucleoplasm 6 CDK5, DCTN5, HMGB1, HPGDS, JAK2, PRAC1
Cell membrane 7 CDK5, GRIN1, GRIN2A, HMGB1, SLC38A3, SLC38A5, SLC6A4
lamellipodium 1 CDK5
Cell projection, growth cone 1 CDK5
Multi-pass membrane protein 5 GRIN1, GRIN2A, SLC38A3, SLC38A5, SLC6A4
Synapse 4 CDK5, GRIN1, GRIN2A, SLC6A4
cell junction 1 CDK5
cell surface 3 GRIN1, GRIN2A, HMGB1
glutamatergic synapse 2 GRIN2A, JAK2
growth cone 1 CDK5
lysosomal membrane 1 GAA
mitochondrial inner membrane 1 CYP2E1
neuromuscular junction 1 CDK5
neuronal cell body 2 CDK5, INHA
postsynapse 1 JAK2
presynaptic membrane 2 GRIN2A, SLC6A4
synaptic vesicle 2 GRIN1, GRIN2A
Lysosome 1 GAA
Presynapse 2 CDK5, SLC6A4
endosome 1 HMGB1
plasma membrane 11 BCHE, CDK5, F2, GAA, GRIN1, GRIN2A, HMGB1, JAK2, SLC38A3, SLC38A5, SLC6A4
terminal bouton 1 GRIN1
Membrane 9 CDK5, CYP1B1, GAA, GRIN1, GRIN2A, JAK2, SLC38A3, SLC38A5, SLC6A4
apical plasma membrane 1 SLC38A3
axon 1 CDK5
basolateral plasma membrane 1 SLC38A3
caveola 1 JAK2
extracellular exosome 2 F2, GAA
Lysosome membrane 1 GAA
endoplasmic reticulum 2 GRIN2A, HMGB1
extracellular space 5 BCHE, F2, HMGB1, INHA, MSMP
lysosomal lumen 1 GAA
mitochondrion 2 CYP1B1, DHFR
protein-containing complex 1 ACR
intracellular membrane-bounded organelle 4 CYP1B1, CYP2E1, GAA, HPGDS
Microsome membrane 2 CYP1B1, CYP2E1
filopodium 1 CDK5
postsynaptic density 3 CDK5, GRIN1, GRIN2A
protein kinase 5 complex 1 CDK5
Secreted 6 BCHE, F2, GAA, HMGB1, INHA, MSMP
extracellular region 6 ACR, BCHE, F2, GAA, HMGB1, INHA
cytoplasmic side of plasma membrane 1 JAK2
excitatory synapse 1 GRIN1
Extracellular side 1 HMGB1
photoreceptor inner segment 1 INHA
photoreceptor outer segment 1 INHA
nuclear membrane 1 DCTN5
dendritic spine 2 GRIN1, GRIN2A
perikaryon 1 CDK5
Golgi-associated vesicle 1 ACR
postsynaptic membrane 3 GRIN1, GRIN2A, SLC6A4
Cell projection, lamellipodium 1 CDK5
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 2 JAK2, SLC6A4
Cell junction, focal adhesion 1 SLC6A4
Cytoplasm, cytoskeleton 1 DCTN5
focal adhesion 2 JAK2, SLC6A4
Cell projection, dendritic spine 1 GRIN2A
collagen-containing extracellular matrix 1 F2
Postsynaptic cell membrane 2 GRIN1, GRIN2A
Cell projection, neuron projection 1 SLC6A4
neuron projection 4 CDK5, GRIN1, GRIN2A, SLC6A4
Chromosome 1 HMGB1
cytoskeleton 1 JAK2
inhibin A complex 1 INHA
blood microparticle 2 BCHE, F2
Basolateral cell membrane 1 SLC38A3
Endomembrane system 2 JAK2, SLC6A4
endosome lumen 1 JAK2
Chromosome, centromere, kinetochore 1 DCTN5
Cytoplasmic vesicle membrane 1 GRIN2A
tertiary granule membrane 1 GAA
euchromatin 1 JAK2
[Isoform 1]: Cytoplasm 1 CDK5
Synaptic cell membrane 1 GRIN1
synaptic membrane 2 GRIN1, GRIN2A
ficolin-1-rich granule lumen 1 HMGB1
secretory granule lumen 1 HMGB1
Golgi lumen 1 F2
endoplasmic reticulum lumen 2 BCHE, F2
transcription repressor complex 1 HMGB1
dynactin complex 1 DCTN5
kinetochore 1 DCTN5
azurophil granule membrane 1 GAA
postsynaptic density membrane 2 GRIN1, GRIN2A
nuclear envelope lumen 1 BCHE
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
extrinsic component of cytoplasmic side of plasma membrane 1 JAK2
synaptic cleft 1 GRIN1
ficolin-1-rich granule membrane 1 GAA
NMDA selective glutamate receptor complex 2 GRIN1, GRIN2A
condensed chromosome 1 HMGB1
extrinsic component of plasma membrane 1 JAK2
granulocyte macrophage colony-stimulating factor receptor complex 1 JAK2
interleukin-12 receptor complex 1 JAK2
interleukin-23 receptor complex 1 JAK2
cyclin-dependent protein kinase holoenzyme complex 1 CDK5
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
inhibin B complex 1 INHA
inhibin-betaglycan-ActRII complex 1 INHA
acrosomal matrix 1 ACR
autolysosome lumen 1 GAA
serotonergic synapse 1 SLC6A4


文献列表

  • Yuan-Ping Pang, Jewn Giew Park, Shaohua Wang, Anuradha Vummenthala, Rajesh K Mishra, John E McLaughlin, Rong Di, Jennifer Nielsen Kahn, Nilgun E Tumer, Laszlo Janosi, Jon Davis, Charles B Millard. Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach. PloS one. 2011 Mar; 6(3):e17883. doi: 10.1371/journal.pone.0017883. [PMID: 21455295]
  • Qing-Dong Huang, Guo-Xing Zhong, Yang Zhang, Jiang Ren, Yun Fu, Ji Zhang, Wen Zhu, Xiao-Qi Yu. Cyclen-based cationic lipids for highly efficient gene delivery towards tumor cells. PloS one. 2011; 6(8):e23134. doi: 10.1371/journal.pone.0023134. [PMID: 21887233]
  • M P Kolomytseva, I P Solianikova, E L Golovlev, L A Golovleva. [Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols]. Prikladnaia biokhimiia i mikrobiologiia. 2005 Sep; 41(5):541-6. doi: ". [PMID: 16240653]
  • Tokujiro Kitagawa, Makoto Asada. Preparation and root growth-inhibitory activity of N-substituted 2-(2-chloroacetamido)-3-(furan-2-yl)propanamides. Chemical & pharmaceutical bulletin. 2005 Sep; 53(9):1183-9. doi: 10.1248/cpb.53.1183. [PMID: 16141594]
  • Akinori Hirashima, Yoko Shigeta, Tomohiko Eiraku, Eiichi Kuwano. Inhibitors of calling behavior of Plodia interpunctella. Journal of insect science (Online). 2003; 3(?):4. doi: 10.1093/jis/3.1.4. [PMID: 15841221]