H-Phg-OH (BioDeep_00001868925)

Main id: BioDeep_00000001197

 


代谢物信息卡片


2-Aminophenylacetic acid

化学式: C8H9NO2 (151.0633)
中文名称: L-(+)-α-苯甘氨酸, Alpha-氨基苯乙酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C(C(=O)O)N
InChI: InChI=1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m0/s1

描述信息

同义名列表

3 个代谢物同义名

2-Aminophenylacetic acid; L-Phenylglycine; H-Phg-OH



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AANAT, APP, DAO, HMGB1, PPARG, RALGDS
Peripheral membrane protein 2 DAO, HMGB1
Endosome membrane 1 NCSTN
Endoplasmic reticulum membrane 1 NCSTN
Nucleus 7 APP, CDX1, ESCO2, HMGB1, PPARA, PPARG, RALGDS
cytosol 5 AANAT, APP, DAO, PPARG, RALGDS
dendrite 1 APP
centrosome 1 SLC1A4
nucleoplasm 4 ESCO2, HMGB1, PPARA, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 5 APP, DAO, DPP4, HMGB1, SLC1A5
lamellipodium 1 DPP4
Cell projection, growth cone 1 APP
Multi-pass membrane protein 2 SLC1A4, SLC1A5
Synapse 2 APP, SLC1A4
cell junction 2 DPP4, ESCO2
cell surface 5 APP, DPP4, HMGB1, ITGA2B, SLC1A4
ciliary rootlet 1 APP
dendritic shaft 1 APP
gamma-secretase complex 1 NCSTN
Golgi apparatus 3 APP, ESCO2, NCSTN
Golgi membrane 1 NCSTN
growth cone 1 APP
lysosomal membrane 3 DPP4, GAA, NCSTN
mitochondrial inner membrane 1 APP
neuromuscular junction 1 APP
presynaptic membrane 1 NCSTN
sarcolemma 1 NCSTN
smooth endoplasmic reticulum 1 APP
synaptic vesicle 2 APP, NCSTN
Cytoplasm, cytosol 1 DAO
Lysosome 1 GAA
endosome 2 APP, HMGB1
plasma membrane 10 APP, DAO, DPP4, GAA, HMGB1, ITGA2B, NCSTN, RALGDS, SLC1A4, SLC1A5
presynaptic active zone 2 APP, DAO
Membrane 7 APP, DPP4, GAA, ITGA2B, NCSTN, SLC1A4, SLC1A5
apical plasma membrane 1 DPP4
axon 1 APP
brush border 1 RALGDS
extracellular exosome 9 APP, DAO, DPP4, GAA, ITGA2B, NCSTN, SLC1A4, SLC1A5, VTN
Lysosome membrane 1 GAA
endoplasmic reticulum 4 APP, HMGB1, NCSTN, VTN
extracellular space 4 APP, DAO, HMGB1, VTN
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 3 AANAT, APP, PPARG
bicellular tight junction 1 DAO
intercellular canaliculus 1 DPP4
intracellular membrane-bounded organelle 3 GAA, PPARG, VTN
pericentric heterochromatin 1 ESCO2
Single-pass type I membrane protein 3 APP, ITGA2B, NCSTN
Secreted 6 APP, DAO, DPP4, GAA, HMGB1, VTN
extracellular region 6 APP, DAO, DPP4, GAA, HMGB1, VTN
Single-pass membrane protein 1 DPP4
Extracellular side 2 DAO, HMGB1
anchoring junction 1 DPP4
external side of plasma membrane 1 ITGA2B
dendritic spine 1 APP
perikaryon 1 APP
cytoplasmic vesicle 1 APP
nucleolus 1 PNMA2
Early endosome 2 APP, NCSTN
Membrane, clathrin-coated pit 1 APP
apical part of cell 1 APP
cell-cell junction 1 APP
clathrin-coated pit 1 APP
COPII-coated ER to Golgi transport vesicle 1 APP
Golgi-associated vesicle 1 APP
recycling endosome 1 APP
spindle midzone 1 APP
Single-pass type II membrane protein 1 DPP4
vesicle 1 APP
Apical cell membrane 1 DPP4
Membrane raft 2 APP, DPP4
focal adhesion 3 DPP4, ITGA2B, NCSTN
Peroxisome 1 DAO
basement membrane 1 VTN
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
collagen-containing extracellular matrix 1 VTN
intermediate filament 1 SLC1A4
receptor complex 2 APP, PPARG
chromatin 4 CDX1, ESCO2, PPARA, PPARG
cell projection 1 DAO
Chromosome 2 ESCO2, HMGB1
Secreted, extracellular space 2 DAO, VTN
Nucleus, nucleolus 1 PNMA2
blood microparticle 2 ITGA2B, VTN
site of double-strand break 1 ESCO2
Endomembrane system 1 DPP4
endosome lumen 1 APP
Cytoplasmic vesicle membrane 1 NCSTN
tertiary granule membrane 1 GAA
Melanosome 3 NCSTN, SLC1A4, SLC1A5
basal plasma membrane 1 SLC1A5
trans-Golgi network membrane 1 APP
ficolin-1-rich granule lumen 1 HMGB1
secretory granule lumen 1 HMGB1
Golgi lumen 2 APP, VTN
endoplasmic reticulum lumen 1 APP
transcription repressor complex 1 HMGB1
platelet alpha granule lumen 1 APP
specific granule lumen 1 DAO
XY body 1 ESCO2
endocytic vesicle 1 DPP4
azurophil granule membrane 2 GAA, NCSTN
nuclear envelope lumen 1 APP
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
ficolin-1-rich granule membrane 1 GAA
chromocenter 1 ESCO2
condensed chromosome 1 HMGB1
platelet alpha granule membrane 1 ITGA2B
integrin complex 1 ITGA2B
lamellipodium membrane 1 DPP4
protein complex involved in cell-matrix adhesion 1 VTN
peptidase inhibitor complex 1 VTN
Parasitophorous vacuole 1 VTN
alphav-beta3 integrin-vitronectin complex 1 VTN
rough endoplasmic reticulum lumen 1 VTN
[C83]: Endoplasmic reticulum 1 APP
[C99]: Early endosome 1 APP
[Soluble APP-beta]: Secreted 1 APP
[Amyloid-beta protein 40]: Cell surface 1 APP
[Amyloid-beta protein 42]: Cell surface 1 APP
[Gamma-secretase C-terminal fragment 59]: Nucleus 1 APP
Cell projection, lamellipodium membrane 1 DPP4
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
integrin alphaIIb-beta3 complex 1 ITGA2B
Cell projection, invadopodium membrane 1 DPP4
autolysosome lumen 1 GAA
[Dipeptidyl peptidase 4 soluble form]: Secreted 1 DPP4


文献列表

  • Hong Zhang, Cailong Zhao, Huanlin Zheng, Xiaocui Chen, Biao Chen, Zhibing Wu. Design, Synthesis and Bioassay of 2-Phenylglycine Derivatives as Potential Pesticide Candidates. Chemistry & biodiversity. 2023 Jan; 20(1):e202200957. doi: 10.1002/cbdv.202200957. [PMID: 36515624]
  • Alan C Foster, Natalie Rangel-Diaz, Ursula Staubli, Jia-Ying Yang, Mahmud Penjwini, Veena Viswanath, Yong-Xin Li. Phenylglycine analogs are inhibitors of the neutral amino acid transporters ASCT1 and ASCT2 and enhance NMDA receptor-mediated LTP in rat visual cortex slices. Neuropharmacology. 2017 Nov; 126(?):70-83. doi: 10.1016/j.neuropharm.2017.08.010. [PMID: 28807674]
  • Karin Halbmair, Janine Wegner, Ulf Diederichsen, Marina Bennati. Pulse EPR Measurements of Intramolecular Distances in a TOPP-Labeled Transmembrane Peptide in Lipids. Biophysical journal. 2016 Dec; 111(11):2345-2348. doi: 10.1016/j.bpj.2016.10.022. [PMID: 27836102]
  • Yawei Zhao, Rongrong Feng, Guosong Zheng, Jinzhong Tian, Lijun Ruan, Mei Ge, Weihong Jiang, Yinhua Lu. Involvement of the TetR-Type Regulator PaaR in the Regulation of Pristinamycin I Biosynthesis through an Effect on Precursor Supply in Streptomyces pristinaespiralis. Journal of bacteriology. 2015 Jun; 197(12):2062-71. doi: 10.1128/jb.00045-15. [PMID: 25868645]