2-Deoxyadenosine-5-diphosphate (BioDeep_00001868816)

Main id: BioDeep_00000001316

 

BioNovoGene_Lab2019


代谢物信息卡片


2-Deoxyadenosine-5-diphosphate

化学式: C10H15N5O9P2 (411.0345)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)OP(=O)(O)O)O
InChI: InChI=1S/C10H15N5O9P2/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1

描述信息

COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

2 个代谢物同义名

2-Deoxyadenosine-5-diphosphate; dADP



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ADA, APAF1, CASP9, CMPK2, GUCY1A1, HPRT1, MYLK, NME1, NPM1, NT5C2, PKM, PNP, PNPT1
Golgi apparatus, trans-Golgi network membrane 1 CALN1
Peripheral membrane protein 2 ADA, PNPT1
Endoplasmic reticulum membrane 2 PNPT1, UGT1A1
Nucleus 7 ACADS, ADK, APAF1, CASP9, NME1, NPM1, PKM
cytosol 14 ADA, ADK, APAF1, CASP9, GUCY1A1, HPRT1, MYLK, NME1, NPM1, NT5C2, PKM, PNP, PNPT1, RAP2B
centrosome 2 ACADS, NPM1
nucleoplasm 5 ACADS, ADK, ATP2B1, CMPK2, NPM1
Cell membrane 3 ADA, ATP2B1, CALN1
Lipid-anchor 1 RAP2B
Cytoplasmic side 1 RAP2B
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
ruffle membrane 1 NME1
Multi-pass membrane protein 1 ATP2B1
Synapse 2 ATP2B1, MYLK
cell junction 1 ADA
cell surface 1 ADA
glutamatergic synapse 2 ATP2B1, GUCY1A1
Golgi apparatus 1 CALN1
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 NT5C2
Lysosome 1 ADA
plasma membrane 7 ADA, ADK, ATP2B1, CALN1, MYLK, RAP2B, UGT1A1
synaptic vesicle membrane 1 ATP2B1
Membrane 9 ADA, APAF1, ATP2B1, CALN1, CSMD1, NME1, NPM1, RAP2B, UGT1A1
basolateral plasma membrane 1 ATP2B1
extracellular exosome 7 APAF1, ATP2B1, HPRT1, NME1, PKM, PNP, RAP2B
endoplasmic reticulum 1 UGT1A1
extracellular space 1 PNP
perinuclear region of cytoplasm 2 CALN1, UGT1A1
bicellular tight junction 1 RAP2B
mitochondrion 5 ACADS, CASP9, CMPK2, PKM, PNPT1
protein-containing complex 3 APAF1, CASP9, NPM1
intracellular membrane-bounded organelle 1 ATP2B1
Single-pass type I membrane protein 1 CSMD1
Secreted 1 PNP
extracellular region 3 APAF1, PKM, PNP
Single-pass membrane protein 1 UGT1A1
Mitochondrion matrix 2 ACADS, PNPT1
mitochondrial matrix 2 ACADS, PNPT1
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NPM1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 1 ADA
Extracellular vesicle 1 PKM
actin cytoskeleton 1 MYLK
nucleolus 1 NPM1
Early endosome 1 NME1
vesicle 1 PKM
Cell projection, lamellipodium 1 MYLK
Cytoplasm, perinuclear region 2 CALN1, UGT1A1
Membrane raft 1 RAP2B
focal adhesion 1 NPM1
GABA-ergic synapse 1 GUCY1A1
Mitochondrion intermembrane space 1 PNPT1
mitochondrial intermembrane space 1 PNPT1
collagen-containing extracellular matrix 1 PKM
lateral plasma membrane 1 ATP2B1
cilium 1 PKM
cell projection 1 ATP2B1
Nucleus, nucleolus 1 NPM1
Basolateral cell membrane 1 ATP2B1
Recycling endosome membrane 1 RAP2B
Nucleus, nucleoplasm 1 NPM1
specific granule membrane 1 RAP2B
tertiary granule membrane 1 RAP2B
Presynaptic cell membrane 1 ATP2B1
stress fiber 1 MYLK
trans-Golgi network membrane 1 CALN1
ficolin-1-rich granule lumen 3 APAF1, PKM, PNP
secretory granule lumen 3 APAF1, PKM, PNP
immunological synapse 1 ATP2B1
Single-pass type IV membrane protein 1 CALN1
apoptosome 2 APAF1, CASP9
[Isoform 2]: Cytoplasm 1 ADK
spindle pole centrosome 1 NPM1
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
ribonucleoprotein complex 1 NPM1
[Isoform 1]: Nucleus 1 ADK
protein-DNA complex 1 NPM1
Rough endoplasmic reticulum 1 PKM
guanylate cyclase complex, soluble 1 GUCY1A1
granular component 1 NPM1
cell-cell contact zone 1 RAP2B
ribosome 1 PNPT1
catalytic complex 1 PNPT1
endoplasmic reticulum chaperone complex 1 UGT1A1
photoreceptor ribbon synapse 1 ATP2B1
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
cytochrome complex 1 UGT1A1
caspase complex 1 CASP9
mitochondrial degradosome 1 PNPT1


文献列表

  • E Camaioni, J L Boyer, A Mohanram, T K Harden, K A Jacobson. Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors. Journal of medicinal chemistry. 1998 Jan; 41(2):183-90. doi: 10.1021/jm970433l. [PMID: 9457242]
  • H A Simmonds, D R Webster, D Perrett, S Reiter, R J Levinsky. Formation and degradation of deoxyadenosine nucleotides in inherited adenosine deaminase deficiency. Bioscience reports. 1982 May; 2(5):303-14. doi: 10.1007/bf01115116. [PMID: 6980023]