Mesalamine (BioDeep_00000402576)
Main id: BioDeep_00000001603
代谢物信息卡片
5-Aminosalicylic acid
化学式: C7H7NO3 (153.0426)
中文名称: 5-氨基水杨酸, 美沙拉嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C=C1N)C(=O)O)O
InChI: InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
描述信息
A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EC - Aminosalicylic acid and similar agents
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D018501 - Antirheumatic Agents
CONFIDENCE standard compound; INTERNAL_ID 8621
同义名列表
5 个代谢物同义名
5-Aminosalicylic acid; Mesalamine; Mesalazine; 5-Aminosalicylate; Mesalamine
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:6775
- KEGG: C07138
- KEGGdrug: D00377
- PubChem: 4075
- DrugBank: DB00244
- ChEMBL: CHEMBL704
- MeSH: Mesalamine
- CAS: 89-57-6
- MoNA: SM862104
- PubChem: 9347
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shuling Zhang, Yanwu Li, Gang Chen, Xu Wang, Bin Wu. Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.
Journal of ethnopharmacology.
2024 Jun; 328(?):118131. doi:
10.1016/j.jep.2024.118131. [PMID: 38565408] - Yili Tao, Lai Wang, Xiaofeng Ye, Xin Qian, Danye Pan, Xiaoyu Dong, Qian Jiang, Po Hu. Huang Qin decoction increases SLC6A4 expression and blocks the NFκB-mediated NLRP3/Caspase1/GSDMD pathway to disrupt colitis-associated carcinogenesis.
Functional & integrative genomics.
2024 Mar; 24(2):55. doi:
10.1007/s10142-024-01334-x. [PMID: 38467948] - Yulin Ye, Limin Liu, Zelin Feng, Yifei Liu, Junming Miao, Xinyue Wei, Huizhen Li, Jie Yang, Xiaocang Cao, Jingwen Zhao. The ERK-cPLA2-ACSL4 axis mediating M2 macrophages ferroptosis impedes mucosal healing in ulcerative colitis.
Free radical biology & medicine.
2024 Mar; 214(?):219-235. doi:
10.1016/j.freeradbiomed.2024.02.016. [PMID: 38367927] - Hongyun Xu, Chunyu Wu, Danning Wang, Haiqiang Wang. Alleviating effect of Nexrutine on mucosal inflammation in mice with ulcerative colitis: Involvement of the RELA suppression.
Immunity, inflammation and disease.
2024 Jan; 12(1):e1147. doi:
10.1002/iid3.1147. [PMID: 38270298] - Hamid Alghurabi, Huda Jassim Muhammad, Tatsuaki Tagami, Koki Ogawa, Tetsuya Ozeki. Optimization, cellular uptake, and in vivo evaluation of Eudragit S100-coated bile salt-containing liposomes for oral colonic delivery of 5-aminosalicylic acid.
International journal of pharmaceutics.
2023 Dec; 648(?):123597. doi:
10.1016/j.ijpharm.2023.123597. [PMID: 37952559] - Rong-Lin Wu, Hui-Chao Xu, Zi-Wen Jiang, Hai-Jun Wang, Yu-Xia Cao, Fan-Min Kong, Ai-Ai Dong, Rang-Qian Li, Lai-Xi Ji. [Effect of electroacupuncture on colonic autophagy and AMPK/mTOR signaling pathway in rats with acute ulcerative colitis].
Zhen ci yan jiu = Acupuncture research.
2023 Aug; 48(8):818-24. doi:
10.13702/j.1000?0607.20220863. [PMID: 37614141] - Qiaoli Sun, Yingjue Tang, Liang Dai, Zhipeng Tang, Wenjun Zhou, Tao Wu, Guang Ji. Serum Bile Acid Metabolites Predict the Therapeutic Effect of Mesalazine in Patients with Ulcerative Colitis.
Journal of proteome research.
2023 Apr; 22(4):1287-1297. doi:
10.1021/acs.jproteome.2c00820. [PMID: 36921116] - Cheng Jing, Lü Shangbin, Zhang Yi, H U Shuangyuan, Wei Pengfei, Zhou Wenhua, Shi Junfeng. Efficacy of Qifu Lizhong enema prescription on intestinal mucosal tight junction function modulation of ulcerative colitis rat model.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2023 Apr; 43(2):303-311. doi:
10.19852/j.cnki.jtcm.20220922.002. [PMID: 36994518] - Wenlong Fu, Lei Xie, Jicheng Yu, Yanjun He, Jie Zeng, Jian Liu, Kang Liang, Pu Chen, Lei Jiang, Zhen Gu, Biao Kong. In Situ Interfacial Super-Assembly of Nanobiohybrids through Plant for Food-Grade Oral Medicine.
ACS applied materials & interfaces.
2023 Feb; 15(5):7282-7293. doi:
10.1021/acsami.2c19791. [PMID: 36701261] - L I Yue, Wen Shuting, Zhao Runyuan, Fan Dongmei, Zhao Dike, Liu Fengbin, M I Hong. Efficacy of active ingredients in Qingdai on ulcerative colitis: a network pharmacology-based evaluation.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2023 02; 43(1):124-133. doi:
10.19852/j.cnki.jtcm.2023.01.011. [PMID: 36640003] - Meng-Ru Liu, Hui Li, Lan-Fu Wei, Xiao-Tong Liu, Zhen-Tao An, Li-Mei Gu, Yao-Zhou Tian. [Effects of Huangqin Tang on NLRP3/Caspase-1 pathway in mice model of ulcerative colitis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Jan; 48(1):226-233. doi:
10.19540/j.cnki.cjcmm.20221018.502. [PMID: 36725275] - Fatemeh Vazirian, Sara Samadi, Mohammadreza Abbaspour, Amirmahdi Taleb, Hadi Bagherhosseini, Hooman Mosannen Mozaffari, Amir Hooshang Mohammadpour, Seyed Ahmad Emami. Evaluation of the efficacy of Thymus kotschyanus extract as an additive treatment in patients with ulcerative colitis: a randomized double-blind placebo-controlled trial.
Inflammopharmacology.
2022 Dec; 30(6):2145-2152. doi:
10.1007/s10787-022-00991-3. [PMID: 35723850] - Kathryn Clarkston, Rebekah Karns, Anil G Jegga, Mihika Sharma, Sejal Fox, Babajide A Ojo, Phillip Minar, Thomas D Walters, Anne M Griffiths, David R Mack, Brendan Boyle, Neal S LeLeiko, James Markowitz, Joel R Rosh, Ashish S Patel, Sapana Shah, Robert N Baldassano, Marian Pfefferkorn, Cary Sauer, Subra Kugathasan, Yael Haberman, Jeffrey S Hyams, Lee A Denson, Michael J Rosen. Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
Journal of Crohn's & colitis.
2022 Nov; 16(11):1735-1750. doi:
10.1093/ecco-jcc/jjac075. [PMID: 35665804] - Ankit Awasthi, Bimlesh Kumar, Monica Gulati, Sukriti Vishwas, Leander Corrie, Jaskiran Kaur, Rubiya Khursheed, Rozhan Arif Muhammed, Duran Kala, Omji Porwal, Malakapogu Ravindra Babu, M V N L Chaitanya, Ankit Kumar, Narendra Kumar Pandey, Harish Dureja, Dinesh Kumar Chellappan, Niraj Kumar Jha, Gaurav Gupta, Parteek Prasher, Deepak Kumar, Kamal Dua, Sachin Kumar Singh. Novel Nanostructured Lipid Carriers Co-Loaded with Mesalamine and Curcumin: Formulation, Optimization and In Vitro Evaluation.
Pharmaceutical research.
2022 Nov; 39(11):2817-2829. doi:
10.1007/s11095-022-03401-z. [PMID: 36195824] - Ling Huang, Junping Zheng, Guangjun Sun, Huabing Yang, Xiongjie Sun, Xiaowei Yao, Aizhen Lin, Hongtao Liu. 5-Aminosalicylic acid ameliorates dextran sulfate sodium-induced colitis in mice by modulating gut microbiota and bile acid metabolism.
Cellular and molecular life sciences : CMLS.
2022 Aug; 79(8):460. doi:
10.1007/s00018-022-04471-3. [PMID: 35913641] - Ana Aparicio Serrano, Elma Gallego Jiménez, Javier Castro Rodríguez, Pilar Soto Escribano, Eva Iglesias Flores, Sandra Marín Pedrosa, José Manuel Benítez. Mesalazine induced interstitial pneumonitis in the COVID era.
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.
2022 07; 114(7):429-430. doi:
10.17235/reed.2022.8635/2021. [PMID: 35199533] - G L Ma, S G Cao, S L Xia, H Q Zhu, Y Jiang. [A preliminary study on the improved efficacy of mesalazine combined with vitamin D3 in ulcerative colitis].
Zhonghua nei ke za zhi.
2022 Jul; 61(7):785-792. doi:
10.3760/cma.j.cn112138-20210903-00613. [PMID: 35764562] - Vasileios Tsamis, Eleni Tsanaktsidou, Christina Karavasili, Constantinos K Zacharis, Nikolaos Bouropoulos, Dimitrios G Fatouros, Catherine K Markopoulou. Development and validation of HPLC-DAD and LC-(ESI)/MS methods for the determination of sulfasalazine, mesalazine and hydrocortisone 21-acetate in tablets and rectal suppositories: In vitro and ex vivo permeability studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2022 May; 1198(?):123246. doi:
10.1016/j.jchromb.2022.123246. [PMID: 35405570] - James G Moss, Christopher M Parry, Richard C L Holt, Stephen J McWilliam. 5-ASA induced interstitial nephritis in patients with inflammatory bowel disease: a systematic review.
European journal of medical research.
2022 Apr; 27(1):61. doi:
10.1186/s40001-022-00687-y. [PMID: 35488310] - Qian-Ru Cao, Chen Ling, Meng-Jun Liu, Hong Zhang, Shi-Feng Deng. [Electroacupuncture of "Shangjuxu"(ST37) and "Tianshu"(ST25) reduces colonic injury by suppressing NF-κB/NLRP3 signaling in rats with ulcerative colitis].
Zhen ci yan jiu = Acupuncture research.
2022 Apr; 47(4):314-20. doi:
10.13702/j.1000-0607.20210361. [PMID: 35486010] - Bingqing Bai, Huihui Li, Liang Han, Yongyu Mei, Cui Hu, Qiao Mei, Jianming Xu, Xiaochang Liu. Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis.
Molecular medicine reports.
2022 04; 25(4):. doi:
10.3892/mmr.2022.12632. [PMID: 35137923] - Zahra Vaezi, Hamid Asadzadeh Aghdaei, Mosslim Sedghi, Reza Mahdavian, Maryam Molakarimi, Naimeh Hashemi, Hossein Naderi-Manesh. Hemoglobin bio-adhesive nanoparticles as a colon-specific delivery system for sustained release of 5-aminosalicylic acid in the effective treatment of inflammatory bowel disease.
International journal of pharmaceutics.
2022 Mar; 616(?):121531. doi:
10.1016/j.ijpharm.2022.121531. [PMID: 35121044] - Jiaxing Zhao, Bing Zhang, Qing Mao, Kunqi Ping, Peng Zhang, Fengwei Lin, Dan Liu, Yao Feng, Ming Sun, Yan Zhang, Qiu Hua Li, Tingjian Zhang, Yanhua Mou, Shaojie Wang. Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5-ASA-PABA-MAC and 5-ASA-PABA-Diamine for the Treatment of Ulcerative Colitis.
Journal of medicinal chemistry.
2022 03; 65(6):4926-4948. doi:
10.1021/acs.jmedchem.1c02166. [PMID: 35275619] - M H Sanad, Nermien M Gomaa, Nermeen M El Bakary, Ismail T Ibrahim, Ayman Massoud. Radioiodination of balsalazide, bioevaluation, and characterization as a highly selective radiotracer for imaging of ulcerative colitis in mice.
Journal of labelled compounds & radiopharmaceuticals.
2022 03; 65(3):71-82. doi:
10.1002/jlcr.3961. [PMID: 34984721] - David M Alvarado, Juhee Son, Larissa B Thackray, Maria Florencia Gomez Castro, Sarada Prasad, Xueyang Cui, Naomi M Sonnek, Michael S Diamond, Siyuan Ding, Matthew A Ciorba. Mesalamine Reduces Intestinal ACE2 Expression Without Modifying SARS-CoV-2 Infection or Disease Severity in Mice.
Inflammatory bowel diseases.
2022 02; 28(2):318-321. doi:
10.1093/ibd/izab274. [PMID: 34849936] - Christopher Ma, Jenny Jeyarajah, Leonardo Guizzetti, Claire E Parker, Siddharth Singh, Parambir S Dulai, Geert R D'Haens, William J Sandborn, Brian G Feagan, Vipul Jairath. Modeling Endoscopic Improvement after Induction Treatment With Mesalamine in Patients With Mild-to-Moderate Ulcerative Colitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2022 02; 20(2):447-454.e1. doi:
10.1016/j.cgh.2020.11.040. [PMID: 33279779] - Xiao-Lan Su, Tao Zhang, Song Guo, Xin Wang, Lin Chen, Wei Wei. Efficacy of Wumei Baijiang prescription on regulatory T cells / helper T cells Immune balance in mice with ulcerative coliti.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2022 02; 42(1):30-38. doi:
. [PMID: 35294120] - Marouf Alhalabi, Kamal Alaa Eddin, Fadwa Ali, Ahmad Abbas. SARS-CoV-2 (COVID-19) pneumonia patient treated with two doses of infliximab within 2 weeks for acute severe ulcerative colitis: A case report.
Medicine.
2022 Jan; 101(4):e28722. doi:
10.1097/md.0000000000028722. [PMID: 35089243] - Xinyi Guo, Changxing Liu, Yahui Huang. Efficacy and Safety of Vitamin D Adjuvant Therapy for Ulcerative Colitis: A Meta-Analysis.
Computational and mathematical methods in medicine.
2022; 2022(?):6836942. doi:
10.1155/2022/6836942. [PMID: 35912148] - Rejani Cristine Faustino Dos Santos, Wilson Roberto Catapani, André Akira Ramos Takahashi, Jaques Waisberg. C-reactive protein levels and prevalence of leukopenia in patients with inflammatory bowel disease treated with azathioprine and/or mesalazine: a real-life study.
Einstein (Sao Paulo, Brazil).
2022; 20(?):eAO6500. doi:
10.31744/einstein_journal/2022ao6500. [PMID: 35584442] - Amandeep Singh, Uttam Kumar Mandal, Raj Kumar Narang. Development and In Vivo Evaluation of Pectin Based Enteric Coated Microparticles Loaded with Mesalamine and Saccharomyces boulardii for Management of Ulcerative Colitis.
Assay and drug development technologies.
2022 01; 20(1):22-34. doi:
10.1089/adt.2021.052. [PMID: 34780287] - Burhan Ceylan, Evrim Kepekci Tekkeli, Cem Önal. Development of An HPLC Method for the Determination of Mesalazine in Human Plasma by Fluorimetric Derivatization and Application to A Prototype Pharmacokinetic Study.
Journal of fluorescence.
2022 Jan; 32(1):319-325. doi:
10.1007/s10895-021-02848-4. [PMID: 34797459] - Masaki Wakai, Ryohei Hayashi, Yoshitaka Ueno, Kana Onishi, Takeshi Takasago, Takuro Uchida, Hidehiko Takigawa, Ryo Yuge, Yuji Urabe, Shiro Oka, Yasuhiko Kitadai, Shinji Tanaka. Promoting mechanism of serum amyloid a family expression in mouse intestinal epithelial cells.
PloS one.
2022; 17(3):e0264836. doi:
10.1371/journal.pone.0264836. [PMID: 35303008] - Ryan C Ungaro, Erica J Brenner, Manasi Agrawal, Xian Zhang, Michael D Kappelman, Jean-Frederic Colombel. Impact of Medications on COVID-19 Outcomes in Inflammatory Bowel Disease: Analysis of More Than 6000 Patients From an International Registry.
Gastroenterology.
2022 Jan; 162(1):316-319.e5. doi:
10.1053/j.gastro.2021.09.011. [PMID: 34529987] - Fei Xie, Shichao Li, Yao Fan, Wusheng Li, Qijun Lv, Xin Sun, Yingshuang Chen, Xiangdong Yang. Efficacy and Safety of Bifidobacterium Quadruple Viable Bacteria Combined with Mesalamine against UC Management: A Systematic Review and Meta-Analysis.
Oxidative medicine and cellular longevity.
2022; 2022(?):8272371. doi:
10.1155/2022/8272371. [PMID: 36238645] - Yu Liu, Yingjie Sun, Xince Wang, Dongsheng Wang, Li Zeng, Qingge Lu. Efficacy of the Panax Notoginseng Ejiao Suppository in the Treatment of Patients with Ulcerative Proctitis and Its Effect on Inflammatory Response and Immune Function.
Disease markers.
2022; 2022(?):1479964. doi:
10.1155/2022/1479964. [PMID: 36188425] - Chenthan Krishnakumar, Ashwin N Ananthakrishnan, Brendan M Boyle, Anne M Griffiths, Neal S LeLeiko, David R Mack, James F Markowitz, Joel R Rosh, Cary G Sauer, Thomas D Walters, Erin Bonkowski, Lee A Denson, Jeffrey S Hyams, Subra Kugathasan. Early Change in Fecal Calprotectin Predicts One-Year Outcome in Children Newly Diagnosed With Ulcerative Colitis.
Journal of pediatric gastroenterology and nutrition.
2022 01; 74(1):72-78. doi:
10.1097/mpg.0000000000003291. [PMID: 34433783] - Peng-Yu Chen, Chong Yuan, Zong-Chao Hong, Ying Zhang, Xin-Ge Ke, Bing Yu, Chen Wang, Xue-Cheng Xiao, He-Zhen Wu, Yan-Fang Yang. Revealing the mechanism of 'Huai Hua San' in the treatment of ulcerative colitis based on network pharmacology and experimental study.
Journal of ethnopharmacology.
2021 Dec; 281(?):114321. doi:
10.1016/j.jep.2021.114321. [PMID: 34118340] - Isabel Garrido, Ana Luísa Santos, Joanne Lopes, Susana Lopes, Guilherme Macedo. 'Hepatotoxicity in inflammatory bowel disease: mesalazine, the forgotten drug'.
European journal of gastroenterology & hepatology.
2021 12; 33(1S Suppl 1):e1067-e1070. doi:
10.1097/meg.0000000000002306. [PMID: 35048663] - Manja Newe, Theresa A Kant, Maximilian Hoffmann, Johanna S E Rausch, Luise Winter, Karolina Künzel, Erik Klapproth, Claudia Günther, Stephan R Künzel. Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice.
Naunyn-Schmiedeberg's archives of pharmacology.
2021 11; 394(11):2233-2244. doi:
10.1007/s00210-021-02135-w. [PMID: 34410453] - Mohamed Attauabi, Jakob Seidelin, Johan Burisch. Association between 5-aminosalicylates in patients with IBD and risk of severe COVID-19: an artefactual result of research methodology?.
Gut.
2021 10; 70(10):2020-2022. doi:
10.1136/gutjnl-2021-324397. [PMID: 33658323] - Lucie Weislinger, Lucas Guillo, Ferdinando D'Amico, Silvio Danese, Hamza Achit, Carole Ayav, Francis Guillemin, Laurent Peyrin-Biroulet, Luc Frimat. Knowledge of 5-aminosalicylic acid nephrotoxicity and adherence to kidney function monitoring of patients with inflammatory bowel disease.
European journal of gastroenterology & hepatology.
2021 09; 33(9):1148-1152. doi:
10.1097/meg.0000000000002008. [PMID: 33252416] - Satyaki Roy, Shehzad Z Sheikh, Terrence S Furey. A machine learning approach identifies 5-ASA and ulcerative colitis as being linked with higher COVID-19 mortality in patients with IBD.
Scientific reports.
2021 08; 11(1):16522. doi:
10.1038/s41598-021-95919-2. [PMID: 34389789] - Shuying Li, Yan Yin, Dan Xiao, Yong Zou. Supplemental bifid triple viable capsule treatment improves inflammatory response and T cell frequency in ulcerative colitis patients.
BMC gastroenterology.
2021 Aug; 21(1):314. doi:
10.1186/s12876-021-01887-2. [PMID: 34348654] - Hiromu Morikubo, Taku Kobayashi, Ryo Ozaki, Shinji Okabayashi, Satoshi Kuronuma, Osamu Takeuchi, Tenyo Shiba, Hiroki Kiyohara, Mao Matsubayashi, Shintaro Sagami, Masaru Nakano, Osamu Ikezaki, Tadakazu Hisamatsu, Yoichi Tanaka, Toshifumi Hibi. Differential effects of mesalazine formulations on thiopurine metabolism through thiopurine S-methyltransferase inhibition.
Journal of gastroenterology and hepatology.
2021 Aug; 36(8):2116-2124. doi:
10.1111/jgh.15411. [PMID: 33470487] - Hong Shen, Shengsheng Zhang, Wenxia Zhao, Shunping Ren, Xiao Ke, Qinghua Gu, Zhipeng Tang, Jingri Xie, Suning Chen, Yan Chen, Jiandong Zou, Lu Zhang, Zhaofeng Shen, Kai Zheng, Yajun Liu, Peiqing Gu, Jiafei Cheng, Jingyi Hu, Lei Zhu. Randomised clinical trial: Efficacy and safety of Qing-Chang-Hua-Shi granules in a multicenter, randomized, and double-blind clinical trial of patients with moderately active ulcerative colitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Jul; 139(?):111580. doi:
10.1016/j.biopha.2021.111580. [PMID: 33857914] - Lucas Guillo, Ferdinando D'Amico, Hamza Achit, Carole Ayav, Francis Guillemin, Silvio Danese, Luc Frimat, Laurent Peyrin-Biroulet. Kidney function monitoring to prevent 5-aminosalicylic acid nephrotoxicity: What the gastroenterologist should know.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2021 Jun; 53(6):691-696. doi:
10.1016/j.dld.2021.01.015. [PMID: 33563584] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Kohichiroh Nii, Kaoru Okazaki, Hitoshi Okada, Toru Kuboi. Maternal mesalazine-induced neonatal gastrointestinal bleeding.
BMJ case reports.
2021 Apr; 14(4):. doi:
10.1136/bcr-2020-238743. [PMID: 33858883] - Lan Chang, Qin Zhang, Yunqing Tang, Yulai Fang, Renjie Dou, Yuyao Chu, Yufeng Xia, Zhifeng Wei, Li Chen, Yue Dai. Synthesis of norisoboldine derivatives and bioactivity assay for inducing the generation of regulatory T cells.
Bioorganic & medicinal chemistry letters.
2021 04; 37(?):127844. doi:
10.1016/j.bmcl.2021.127844. [PMID: 33556569] - Hélène Céruti, Gilles Kayem, Lucie Guilbaud, Chloé Dussaux, Anne Gervais, Aurélie Beaufrère, Benoit Coffin, Laurent Mandelbrot, Emeline Maisonneuve. Intrahepatic cholestasis of pregnancy associated with azathioprine: A case series.
Journal of gynecology obstetrics and human reproduction.
2021 Apr; 50(4):102083. doi:
10.1016/j.jogoh.2021.102083. [PMID: 33601075] - Wei Zhou, Haiyin Zhang, Yibin Pan, Yanwu Xu, Yongqing Cao. circRNA expression profiling of colon tissue from mesalazine-treated mouse of inflammatory bowel disease reveals an important circRNA-miRNA-mRNA pathway.
Aging.
2021 03; 13(7):10187-10207. doi:
10.18632/aging.202780. [PMID: 33819198] - Fernando Rizzello, Carlo Calabrese, Marco Salice, Lucia Calandrini, Hana Privitera, Laura Melotti, Giulia Peruzzi, Nikolas Dussias, Andrea Belluzzi, Eleonora Scaioli, Anastasio Decorato, Antonio Siniscalchi, Eleonora Filippone, Silvio Laureti, Matteo Rottoli, Gilberto Poggioli, Paolo Gionchetti. COVID-19 in IBD: The experience of a single tertiary IBD center.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2021 03; 53(3):271-276. doi:
10.1016/j.dld.2020.12.012. [PMID: 33451910] - Niels Vande Casteele, Abhijeet Jakate, Brian McNamee, William J Sandborn. Similar pharmacokinetics of three dosing regimens comprising two oral delayed-release mesalamine formulations in healthy adult volunteers: Randomised, open-label, parallel-group study.
British journal of clinical pharmacology.
2021 03; 87(3):1141-1149. doi:
10.1111/bcp.14479. [PMID: 32671846] - Tong Wang, Hua Lu, Fangyuan Li, Qi Zhang. Effect of Kangfuxin Liquid enema combined with mesalazine on gestational outcomes and quality of life in child-bearing female with active ulcerative colitis: A protocol for randomized, double-blind, controlled trial.
Medicine.
2021 Feb; 100(5):e23915. doi:
10.1097/md.0000000000023915. [PMID: 33592844] - Kun Liu, Bingjie Jia, Liping Zhou, Lei Xing, Lvying Wu, Yuanyuan Li, Jungang Lu, Lei Zhang, Su Guan. Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model.
Journal of proteome research.
2021 02; 20(2):1371-1381. doi:
10.1021/acs.jproteome.0c00757. [PMID: 33356298] - Zhenglan Han, Hanyan Wang, Dongmei Guo, Jingping Zhang. Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis.
Aging.
2021 02; 13(4):5087-5103. doi:
10.18632/aging.202427. [PMID: 33535180] - Erica J Brenner, Bénédicte Pigneur, Gili Focht, Xian Zhang, Ryan C Ungaro, Jean-Frederic Colombel, Dan Turner, Michael D Kappelman, Frank M Ruemmele. Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2021 02; 19(2):394-396.e5. doi:
10.1016/j.cgh.2020.10.010. [PMID: 33059040] - Nandini Nataraj, Siva Kumar Krishnan, Tse-Wei Chen, Shen-Ming Chen, Bih-Show Lou. Ni-Doped ZrO2 nanoparticles decorated MW-CNT nanocomposite for the highly sensitive electrochemical detection of 5-amino salicylic acid.
The Analyst.
2021 Jan; 146(2):664-673. doi:
10.1039/d0an01507e. [PMID: 33206733] - Satoshi Tamura, Natsuki Ishida, Takahiro Miyazu, Shunya Onoue, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Moriya Iwaizumi, Satoshi Osawa, Takahisa Furuta, Ken Sugimoto. Mesalazine granule formulation improves clinical data in Crohn's disease compared with tablet formulation.
Scientific reports.
2020 12; 10(1):21353. doi:
10.1038/s41598-020-78603-9. [PMID: 33288852] - Mario-Livio Jeličić, Edvin Brusač, Daniela Amidžić Klarić, Biljana Nigović, Nikša Turk, Ana Mornar. A chromatographic approach to development of 5-aminosalicylate/folic acid fixed-dose combinations for treatment of Crohn's disease and ulcerative colitis.
Scientific reports.
2020 11; 10(1):20838. doi:
10.1038/s41598-020-77654-2. [PMID: 33257796] - Chun Zhong, Xiaoming Cheng, Bo Jia, PeiYu Xiong, Jinhua Lu, Peixu Zhang, Xinglong Liu, Yunhui Chen. Gancao Xiexin decoction combined with mesalazine in the treatment of ulcerative colitis: A protocol for a systematic review and meta-analysis.
Medicine.
2020 Nov; 99(47):e23038. doi:
10.1097/md.0000000000023038. [PMID: 33217804] - Dagmar Schierová, Jan Březina, Jakub Mrázek, Kateřina Olša Fliegerová, Simona Kvasnová, Lukáš Bajer, Pavel Drastich. Gut Microbiome Changes in Patients with Active Left-Sided Ulcerative Colitis after Fecal Microbiome Transplantation and Topical 5-aminosalicylic Acid Therapy.
Cells.
2020 10; 9(10):. doi:
10.3390/cells9102283. [PMID: 33066233] - Danfeng Lan, Yunling Wen, Xiangqian Dong, Qin Yang, Yan Liu, Kunhua Wang, Hongying Li, Yinglei Miao. The endogenous ligand for guanylate cyclase-C activation reliefs intestinal inflammation in the DSS colitis model.
Acta biochimica Polonica.
2020 Sep; 67(3):333-340. doi:
10.18388/abp.2020_2881. [PMID: 32894825] - Alberto Vílchez, Juan Antonio Orts, Sarah Frédérique Scheirs, Guillem Benavent. [Mesalazine renal lithiasis.].
Archivos espanoles de urologia.
2020 Jul; 73(6):561-564. doi:
NULL. [PMID: 32633252] - Felipe Varum, Ana Cristina Freire, Roberto Bravo, Abdul W Basit. OPTICORE™, an innovative and accurate colonic targeting technology.
International journal of pharmaceutics.
2020 Jun; 583(?):119372. doi:
10.1016/j.ijpharm.2020.119372. [PMID: 32344022] - Stefano Mazza, Andrea Sorce, Flora Peyvandi, Maurizio Vecchi, Flavio Caprioli. A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis.
Gut.
2020 06; 69(6):1148-1149. doi:
10.1136/gutjnl-2020-321183. [PMID: 32245909] - Masaki Wakai, Ryohei Hayashi, Shinji Tanaka, Toshikatsu Naito, Junko Kumada, Motonobu Nomura, Hidehiko Takigawa, Shiro Oka, Yoshitaka Ueno, Masanori Ito, Kazuaki Chayama. Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission.
BMC gastroenterology.
2020 Apr; 20(1):85. doi:
10.1186/s12876-020-01229-8. [PMID: 32245401] - Fatih Yilmaz, Bora Uslu, Bahar Akkaya, Ramazan Cetinkaya. Mesalazine induced focal segmental glomerulosclerosis in a patient with ulcerative colitis.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2020 Mar; 31(2):528-532. doi:
10.4103/1319-2442.284031. [PMID: 32394929] - Xu Jun, Chen Ning, Song Yang, Wu Zhe, Wu Na, Zhang Yifan, Ren Xinhua, Liu Yulan. Alteration of Fungal Microbiota After 5-ASA Treatment in UC Patients.
Inflammatory bowel diseases.
2020 02; 26(3):380-390. doi:
10.1093/ibd/izz207. [PMID: 31750918] - Ruixian Niu, Jiangtao Zheng, Dongmei Ding, Weian Kuang, Fengyan Lu, Xunguo Yin. Giant pyoderma gangrenosum in a patient with ulcerative colitis: A case report.
Medicine.
2020 Feb; 99(6):e18795. doi:
10.1097/md.0000000000018795. [PMID: 32028391] - Ramaraj Sukanya, Settu Ramki, Shen-Ming Chen, Raj Karthik. Ultrasound treated cerium oxide/tin oxide (CeO2/SnO2) nanocatalyst: A feasible approach and enhanced electrode material for sensing of anti-inflammatory drug 5-aminosalicylic acid in biological samples.
Analytica chimica acta.
2020 Feb; 1096(?):76-88. doi:
10.1016/j.aca.2019.10.059. [PMID: 31883594] - X-E Jiang, S-M Yang, X-J Zhou, Y Zhang. Effects of mesalazine combined with bifid triple viable on intestinal flora, immunoglobulin and levels of cal, MMP-9, and MPO in feces of patients with ulcerative colitis.
European review for medical and pharmacological sciences.
2020 01; 24(2):935-942. doi:
10.26355/eurrev_202001_20079. [PMID: 32017001] - Avinash Adiga, David S Goldfarb. The Association of Mesalamine With Kidney Disease.
Advances in chronic kidney disease.
2020 01; 27(1):72-76. doi:
10.1053/j.ackd.2019.09.002. [PMID: 32147005] - Su-Hua Zhang, Yao Li, Shan-Shan Wei, Lin Guo, Xiao-Mei Huang, Ying Chen, Xiang-Xin Wu, Hua-Lin Cai, Bi-Kui Zhang. Effects of Differential Food Patterns on the Pharmacokinetics of Enteric-Coated Mesalazine Tablets in the Same Cohort of Healthy Chinese Volunteers.
Clinical pharmacology in drug development.
2020 01; 9(1):41-49. doi:
10.1002/cpdd.696. [PMID: 31056855] - Li Xu, Yujie Zhang, Xianmin Xue, Jie Liu, Zeng-Shan Li, Guang-Yu Yang, Ying Song, Yan Pan, Yueyun Ma, Sijun Hu, Aidong Wen, Yanyan Jia, Luz Maria Rodriguez, Mary Beth Tull, Kelly Benante, Seema A Khan, Ying Cao, Borko Jovanovic, Ellen Richmond, Asad Umar, Raymond Bergan, Kaichun Wu. A Phase I Trial of Berberine in Chinese with Ulcerative Colitis.
Cancer prevention research (Philadelphia, Pa.).
2020 01; 13(1):117-126. doi:
10.1158/1940-6207.capr-19-0258. [PMID: 31619442] - Maartje M van de Meeberg, Johannes P D Schultheiss, Bas Oldenburg, Herma H Fidder, Alwin D R Huitema. Does the 5-Aminosalicylate Concentration Correlate with the Efficacy of Oral 5-Aminosalicylate and Predict Response in Patients with Inflammatory Bowel Disease? A Systematic Review.
Digestion.
2020; 101(3):245-261. doi:
10.1159/000499331. [PMID: 31013494] - Antonio Tursi, Claudio Cassieri, Raffaele Colucci, Walter Elisei, Marcello Picchio, Giovanni Brandimarte. Budesonide MMX Is Effective in Patients Having Persistent Symptoms and Raised Fecal Calprotectin Following Treatments for Diverticular Disease.
Journal of gastrointestinal and liver diseases : JGLD.
2019 Dec; 28(suppl. 4):45-48. doi:
10.15403/jgld-559. [PMID: 31930223] - Anastasia Foppoli, Alessandra Maroni, Saliha Moutaharrik, Alice Melocchi, Lucia Zema, Luca Palugan, Matteo Cerea, Andrea Gazzaniga. In vitro and human pharmacoscintigraphic evaluation of an oral 5-ASA delivery system for colonic release.
International journal of pharmaceutics.
2019 Dec; 572(?):118723. doi:
10.1016/j.ijpharm.2019.118723. [PMID: 31628978] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Timna Naftali, Lihi Bar-Lev Schleider, Fabiana Sklerovsky Benjaminov, Ido Lish, Fred M Konikoff, Yehuda Ringel. Medical cannabis for inflammatory bowel disease: real-life experience of mode of consumption and assessment of side-effects.
European journal of gastroenterology & hepatology.
2019 Nov; 31(11):1376-1381. doi:
10.1097/meg.0000000000001565. [PMID: 31567639] - Arti Mahto, Sumit Mishra. Design, development and validation of guar gum based pH sensitive drug delivery carrier via graft copolymerization reaction using microwave irradiations.
International journal of biological macromolecules.
2019 Oct; 138(?):278-291. doi:
10.1016/j.ijbiomac.2019.07.063. [PMID: 31310787] - Elif Yorulmaz, Hatice Yorulmaz, Emel Sağlam Gökmen, Serdar Altınay, Suat Hayri Küçük, Oğuzhan Zengi, Duygu Sultan Çelik, Dede Şit. Therapeutic effectiveness of rectally administered fish oil and mesalazine in trinitrobenzenesulfonic acid-induced colitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Oct; 118(?):109247. doi:
10.1016/j.biopha.2019.109247. [PMID: 31351432] - Margarita L Martinez-Fierro, Idalia Garza-Veloz, Maria R Rocha-Pizaña, Edith Cardenas-Vargas, Miguel A Cid-Baez, Fabiola Trejo-Vazquez, Virginia Flores-Morales, Gabriela A Villela-Ramirez, Ivan Delgado-Enciso, Iram P Rodriguez-Sanchez, Yolanda Ortiz-Castro. Serum cytokine, chemokine, and growth factor profiles and their modulation in inflammatory bowel disease.
Medicine.
2019 Sep; 98(38):e17208. doi:
10.1097/md.0000000000017208. [PMID: 31567972] - Vipul Jairath, Suvi R K Hokkanen, Leonardo Guizzetti, Naomi Boxall, Sarah Campbell-Hill, Haridarshan Patel. No increased risk of nephrotoxicity associated with 5-aminosalicylic acid in IBD: a population-based cohort and nested case-control study.
Alimentary pharmacology & therapeutics.
2019 08; 50(4):416-424. doi:
10.1111/apt.15408. [PMID: 31298421] - Hua Fan, Juan Du, Xia Liu, Wei-Wei Zheng, Ze-Hao Zhuang, Cheng-Dang Wang, Rui Gao. Effects of pentasa-combined probiotics on the microflora structure and prognosis of patients with inflammatory bowel disease.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.
2019 Aug; 30(8):680-685. doi:
10.5152/tjg.2019.18426. [PMID: 31418411] - Sifeng Zhu, Chong Yang, Liang Zhang, Shixiao Wang, Mingxu Ma, Jianchun Zhao, Zhiyu Song, Feng Wang, Xianjun Qu, Feng Li, Wenbao Li. Development of M10, myricetin-3-O-β-d-lactose sodium salt, a derivative of myricetin as a potent agent of anti-chronic colonic inflammation.
European journal of medicinal chemistry.
2019 Jul; 174(?):9-15. doi:
10.1016/j.ejmech.2019.04.031. [PMID: 31022552] - Nikos Viazis, Christos Pontas, Konstantinos Karmiris, Ioannis Dimas, Maria Fragaki, Gregorios Paspatis, Ioannis Drygiannakis, Ioannis E Koutroubakis, Dimitris Moschovis, Maria Tzouvala, Georgios Theocharis, Chrysostomos Tsolias, Konstantinos Thomopoulos, Evanthia Zampeli, Georgios Axiaris, Spyros Michopoulos, Eleni Belesiotou, Maria Banasa, Sofia Maraki, Fotini Kouskoumpekou, Georgios Apostolopoulos, Vasiliki Stamouli, Heleni Prifti, Gerasimos J Mantzaris. Prevalence of Clostridium difficile infection among hospitalized inflammatory bowel disease patients in Greece.
European journal of gastroenterology & hepatology.
2019 Jul; 31(7):773-776. doi:
10.1097/meg.0000000000001414. [PMID: 30973416] - Yuan Lu, Guanghong Ding, Handan Zheng, Tingting Lü, Zhe Ma, Huangan Wu, Zhijun Weng, Fang Zhang, Luyi Wu, Huirong Liu, Manwen Xu, Hui Feng. Effect of herb-partitioned moxibustion on dopamine levels and dopamine receptor 1 expression in the colon and central nervous system in rats with Crohn's disease.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2019 06; 39(3):356-363. doi:
". [PMID: 32186008] - Shan-Shan Gong, Yi-Hong Fan, Qing-Qing Han, Bin Lv, Yi Xu. Nested case-control study on risk factors for opportunistic infections in patients with inflammatory bowel disease.
World journal of gastroenterology.
2019 May; 25(18):2240-2250. doi:
10.3748/wjg.v25.i18.2240. [PMID: 31143074] - Jing Zhou, Lu-Yi Wu, Liu Chen, Ya-Jing Guo, Yi Sun, Tao Li, Ji-Meng Zhao, Chun-Hui Bao, Huan-Gan Wu, Yin Shi. Herbs-partitioned moxibustion alleviates aberrant intestinal epithelial cell apoptosis by upregulating A20 expression in a mouse model of Crohn's disease.
World journal of gastroenterology.
2019 May; 25(17):2071-2085. doi:
10.3748/wjg.v25.i17.2071. [PMID: 31114134] - Maya Olaisen, Olav Spigset, Arnar Flatberg, Atle van Beelen Granlund, Wenche Rødseth Brede, Grethe Albrektsen, Elin Synnøve Røyset, Bodil Gilde, Arne Kristian Sandvik, Tom Christian Martinsen, Reidar Fossmark. Mucosal 5-aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis.
Alimentary pharmacology & therapeutics.
2019 05; 49(10):1301-1313. doi:
10.1111/apt.15227. [PMID: 30895635] - Carlos Augusto Real Martinez, Fábio Guilherme Campos, Danilo Toshio Kanno, Eli Cristiano Meneses, Gabrielle Maira Matijascic, Eduardo Felipe Kim Goto, José Aires Pereira. Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream.
Acta cirurgica brasileira.
2019 Apr; 34(4):e201900406. doi:
10.1590/s0102-865020190040000006. [PMID: 31038584] - Jeffrey S Hyams, Sonia Davis Thomas, Nathan Gotman, Yael Haberman, Rebekah Karns, Melanie Schirmer, Angela Mo, David R Mack, Brendan Boyle, Anne M Griffiths, Neal S LeLeiko, Cary G Sauer, David J Keljo, James Markowitz, Susan S Baker, Joel Rosh, Robert N Baldassano, Ashish Patel, Marian Pfefferkorn, Anthony Otley, Melvin Heyman, Joshua Noe, Maria Oliva-Hemker, Paul A Rufo, Jennifer Strople, David Ziring, Stephen L Guthery, Boris Sudel, Keith Benkov, Prateek Wali, Dedrick Moulton, Jonathan Evans, Michael D Kappelman, M Alison Marquis, Francisco A Sylvester, Margaret H Collins, Suresh Venkateswaran, Marla Dubinsky, Vin Tangpricha, Krista L Spada, Bradley Saul, Jessie Wang, Jose Serrano, Kevin Hommel, Urko M Marigorta, Greg Gibson, Ramnik J Xavier, Subra Kugathasan, Thomas Walters, Lee A Denson. Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study.
Lancet (London, England).
2019 04; 393(10182):1708-1720. doi:
10.1016/s0140-6736(18)32592-3. [PMID: 30935734] - Theodoros Paschalis, Myrella Paschali, Amit K J Mandal, Constantinos G Missouris. Plasma N-terminal pro-B-type natriuretic peptide (BNP) in mesalazine-induced myopericarditis.
BMJ case reports.
2019 Apr; 12(4):. doi:
10.1136/bcr-2018-229142. [PMID: 30975785] - J B Krajewska, P Pietruszka, D Tomczyk, C Chen, A Owczarek, B Karolewicz, H Czapor-Irzabek, A Gorniak, J Fichna. Evaluation of the effect of liposomes loaded with chlorogenic acid in treatment of 2,4,6-trinitrobenzenesulfonic acid-induced murine colitis.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2019 Apr; 70(2):. doi:
10.26402/jpp.2019.2.10. [PMID: 31443089] - Souvik Mohanta, Sachin Kumar Singh, Bimlesh Kumar, Monica Gulati, Rajesh Kumar, Ankit Kumar Yadav, Sheetu Wadhwa, Jivan Jyoti, Sananda Som, Kamal Dua, Narendra Kumar Pandey. Efficacy of co-administration of modified apple polysaccharide and probiotics in guar gum-Eudragit S100 based mesalamine mini tablets: A novel approach in treating ulcerative colitis.
International journal of biological macromolecules.
2019 Apr; 126(?):427-435. doi:
10.1016/j.ijbiomac.2018.12.154. [PMID: 30572047] - Xin Zheng, Zhen Zhang, Botao Wang, Jiaxin Li, Chongyang Qiu, Qi Zhang, Ximo Wang. Efficacy and safety of once daily versus twice daily mesalazine for mild-to-moderate ulcerative colitis: A meta-analysis of randomized controlled trials.
Medicine.
2019 Apr; 98(14):e15113. doi:
10.1097/md.0000000000015113. [PMID: 30946380] - Xuanyi Meng, Garett Dunsmore, Petya Koleva, Yesmine Elloumi, Richard You Wu, Reed Taylor Sutton, Lindsy Ambrosio, Naomi Hotte, Vivian Nguyen, Karen L Madsen, Levinus A Dieleman, Hongbing Chen, Vivian Huang, Shokrollah Elahi. The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn.
Journal of Crohn's & colitis.
2019 Mar; 13(4):431-441. doi:
10.1093/ecco-jcc/jjy186. [PMID: 30418545]
