Dienestrol (BioDeep_00000006659)

 

Secondary id: BioDeep_00001867701

human metabolite blood metabolite natural product


代谢物信息卡片


4,4-Hydroxy-gamma,delta-diphenyl-beta,delta-hexadiene

化学式: C18H18O2 (266.1307)
中文名称: 2,3-二苯酚丁二烯, E,E-二烯雌酚, 双烯雌酚
谱图信息: 最多检出来源 Homo sapiens(plant) 22.52%

分子结构信息

SMILES: C/C=C(C(=C/C)/c1ccc(O)cc1)\c1ccc(O)cc1
InChI: InChI=1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3

描述信息

Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of the vulva. Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis).
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03C - Estrogens > G03CC - Estrogens, combinations with other drugs
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03C - Estrogens > G03CB - Synthetic estrogens, plain
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen

同义名列表

14 个代谢物同义名

4,4-Hydroxy-gamma,delta-diphenyl-beta,delta-hexadiene; 4-[4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol; 4,4-Hydroxy-g,delta-diphenyl-b,delta-hexadiene; 4,4-Hydroxy-γ,δ-diphenyl-β,δ-hexadiene; 4,4-Hydroxy-g,δ-diphenyl-b,δ-hexadiene; p,P-(diethylideneethylene)diphenol; Di(p-oxyphenyl)-2,4-hexadiene; Dehydrostilboestrol; Dehydrostilbestrol; E,E-Dienestrol; Dienoestrol; Dienesterol; Dienestrol; Dienestrol



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ESR1, HSD3B2, PGR, PPARG, TBX20, TUBB4B, TYR
Peripheral membrane protein 3 ACHE, CYP11A1, ESR1
Endosome membrane 1 CLCN5
Endoplasmic reticulum membrane 2 CYP17A1, HSD3B2
Mitochondrion membrane 1 CYP11A1
Nucleus 7 ACHE, ESR1, KDR, PGR, PPARG, TBX20, TUBB4B
cytosol 6 CLCN5, ESR1, LIPE, PGR, PPARG, TUBB4B
mitochondrial membrane 1 HSD3B2
nucleoplasm 5 ATP2B1, ESR1, PGR, PPARG, SCNN1G
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 7 ACHE, ATP2B1, CLCN5, ESR1, GLRA2, KDR, LIPE
Cytoplasmic side 1 ESR1
Multi-pass membrane protein 4 ATP2B1, CLCN5, GLRA2, SCNN1G
Golgi apparatus membrane 1 CLCN5
Synapse 3 ACHE, ATP2B1, GLRA2
cell junction 1 KDR
cell surface 1 ACHE
glutamatergic synapse 1 ATP2B1
Golgi apparatus 5 ACHE, ATRN, CLCN5, ESR1, KDR
Golgi membrane 1 CLCN5
lysosomal membrane 1 CLCN5
mitochondrial inner membrane 2 CYP11A1, HSD3B2
neuromuscular junction 1 ACHE
neuronal cell body 1 CYP17A1
presynaptic membrane 1 ATP2B1
synaptic vesicle 1 CLCN5
Cytoplasm, cytosol 1 LIPE
Lysosome 1 TYR
endosome 1 KDR
plasma membrane 9 ACHE, ATP2B1, ATRN, CLCN5, ESR1, GLRA2, KDR, PGR, SCNN1G
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ACHE, ATP2B1, CLCN5, CYP11A1, ESR1, GLRA2, HSD3B2, LIPE
apical plasma membrane 1 SCNN1G
axon 1 CYP17A1
basolateral plasma membrane 1 ATP2B1
caveola 1 LIPE
extracellular exosome 4 ATP2B1, ATRN, SCNN1G, TUBB4B
endoplasmic reticulum 3 CYP17A1, HSD3B2, KDR
extracellular space 5 ACHE, ATRN, CPZ, INSL3, PNLIP
perinuclear region of cytoplasm 4 ACHE, INSL3, PPARG, TYR
mitochondrion 1 CYP11A1
protein-containing complex 1 ESR1
intracellular membrane-bounded organelle 5 ATP2B1, GLRA2, HSD3B2, PPARG, TYR
Microsome membrane 1 CYP17A1
Single-pass type I membrane protein 2 ATRN, TYR
Secreted 3 ACHE, INSL3, PNLIP
extracellular region 5 ACHE, INSL3, KDR, PNLIP, TUBB4B
Single-pass membrane protein 1 HSD3B2
mitochondrial outer membrane 1 PGR
[Isoform 2]: Secreted 2 ATRN, KDR
mitochondrial matrix 1 CYP11A1
Extracellular side 1 ACHE
anchoring junction 1 KDR
transcription regulator complex 1 ESR1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 2 KDR, SCNN1G
Extracellular vesicle 1 TUBB4B
Secreted, extracellular space, extracellular matrix 1 CPZ
microtubule cytoskeleton 1 TUBB4B
nucleolus 1 HSD3B2
Melanosome membrane 1 TYR
Early endosome 2 CLCN5, KDR
apical part of cell 1 CLCN5
Golgi-associated vesicle 1 TYR
Apical cell membrane 1 SCNN1G
Mitochondrion inner membrane 1 CYP11A1
Membrane raft 1 KDR
Cytoplasm, cytoskeleton 1 TUBB4B
microtubule 1 TUBB4B
GABA-ergic synapse 1 GLRA2
basement membrane 1 ACHE
mitochondrial intermembrane space 1 HSD3B2
lateral plasma membrane 1 ATP2B1
Postsynaptic cell membrane 1 GLRA2
receptor complex 2 KDR, PPARG
neuron projection 1 GLRA2
chromatin 4 ESR1, PGR, PPARG, TBX20
cell projection 2 ATP2B1, GLRA2
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
transmembrane transporter complex 1 GLRA2
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 3]: Secreted 1 ATRN
intercellular bridge 2 HSD3B2, TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
sorting endosome 1 KDR
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
chloride channel complex 1 GLRA2
axonemal microtubule 1 TUBB4B
sodium channel complex 1 SCNN1G
Melanosome 1 TYR
euchromatin 1 ESR1
Presynaptic cell membrane 1 ATP2B1
Smooth endoplasmic reticulum membrane 1 HSD3B2
side of membrane 1 ACHE
azurophil granule lumen 1 TUBB4B
immunological synapse 1 ATP2B1
[Isoform 1]: Nucleus 1 ESR1
synaptic cleft 1 ACHE
postsynaptic specialization membrane 1 GLRA2
[Isoform 1]: Cell membrane 1 ATRN
glycinergic synapse 1 GLRA2
[Isoform 4]: Mitochondrion outer membrane 1 PGR
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Manoel M S Lima Filho, Alessandra A Correa, Francisco D C Silva, Francisco A O Carvalho, Lúcia H Mascaro, Thiago M B F Oliveira. A glassy carbon electrode modified with silver nanoparticles and functionalized multi-walled carbon nanotubes for voltammetric determination of the illicit growth promoter dienestrol in animal urine. Mikrochimica acta. 2019 07; 186(8):525. doi: 10.1007/s00604-019-3645-9. [PMID: 31292777]
  • Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. Toxicological sciences : an official journal of the Society of Toxicology. 2015 Feb; 143(2):333-48. doi: 10.1093/toxsci/kfu231. [PMID: 25349334]
  • Huixiao Hong, William S Branham, Stacey L Dial, Carrie L Moland, Hong Fang, Jie Shen, Roger Perkins, Daniel Sheehan, Weida Tong. Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities. Chemical research in toxicology. 2012 Nov; 25(11):2553-66. doi: 10.1021/tx3003406. [PMID: 23013281]
  • Shuyu Nong, Fuhua Lin, Xiaojia Huang, Dongxing Yuan. Preparation of a stir bar sorptive extraction coating based on molecularly imprinted polymer and its application in the extraction of dienestrol and hexestrol in complicated samples. Se pu = Chinese journal of chromatography. 2012 Nov; 30(11):1133-42. doi: 10.3724/sp.j.1123.2012.08034. [PMID: 23451515]
  • George Kaklamanos, Georgios Theodoridis, Themistoklis Dabalis. Determination of anabolic steroids in bovine urine by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 Aug; 877(23):2330-6. doi: 10.1016/j.jchromb.2009.03.033. [PMID: 19375394]
  • Kathrin Schmidt, Carolin Stachel, Petra Gowik. Development and in-house validation of an LC-MS/MS method for the determination of stilbenes and resorcylic acid lactones in bovine urine. Analytical and bioanalytical chemistry. 2008 Jun; 391(4):1199-210. doi: 10.1007/s00216-008-1943-x. [PMID: 18363048]
  • Elisabete Silva, Martin Scholze, Andreas Kortenkamp. Activity of xenoestrogens at nanomolar concentrations in the E-Screen assay. Environmental health perspectives. 2007 Dec; 115 Suppl 1(?):91-7. doi: 10.1289/ehp.9363. [PMID: 18174956]
  • Antoni Rúbies, Albert Cabrera, Francesc Centrich. Determination of synthetic hormones in animal urine by high-performance liquid chromatography/mass spectrometry. Journal of AOAC International. 2007 Mar; 90(2):626-32. doi: 10.1093/jaoac/90.2.626. [PMID: 17474533]
  • Katerina Hájková, Jana Pulkrabová, Jakub Schůrek, Jana Hajslová, Jan Poustka, Michaela Nápravníková, Vladimír Kocourek. Novel approaches to the analysis of steroid estrogens in river sediments. Analytical and bioanalytical chemistry. 2007 Feb; 387(4):1351-63. doi: 10.1007/s00216-006-1026-9. [PMID: 17219098]
  • Titus Alfred Makudali Msagati, Mathew Muzi Nindi. The use of liquid membranes in the multi-residue extraction of stilbenes in a variety of biological matrices and their detection with LC-ES-MS. Annali di chimica. 2006 Nov; 96(11-12):635-46. doi: 10.1002/adic.200690066. [PMID: 17217168]
  • E Weiderpass, K Brismar, R Bellocco, H Vainio, R Kaaks. Serum levels of insulin-like growth factor-I, IGF-binding protein 1 and 3, and insulin and endometrial cancer risk. British journal of cancer. 2003 Nov; 89(9):1697-704. doi: 10.1038/sj.bjc.6601312. [PMID: 14583772]
  • Leslie C Dickson, James D MacNeil, JoAnn Reid, Adrian C E Fesser. Validation of screening method for residues of diethylstilbestrol, dienestrol, hexestrol, and zeranol in bovine urine using immunoaffinity chromatography and gas chromatography/mass spectrometry. Journal of AOAC International. 2003 Jul; 86(4):631-9. doi: . [PMID: 14509418]
  • Yuliya Dobrydneva, Roy L Williams, John A Katzenellenbogen, Paul H Ratz, Peter F Blackmore. Diethylstilbestrol and tetrahydrochrysenes are calcium channel blockers in human platelets: relationship to the stilbene pharmacophore. Thrombosis research. 2003 Apr; 110(1):23-31. doi: 10.1016/s0049-3848(03)00110-5. [PMID: 12877905]
  • M T Islam, S Tahara. Repellent activity of estrogenic compounds toward zoospores of the phytopathogenic fungus Aphanomyces cochlioides. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2001 Mar; 56(3-4):253-61. doi: 10.1515/znc-2001-3-414. [PMID: 11371017]
  • Y Martín. Determination of three anabolic compounds in calf urine by liquid chromatography with photodiode-array detection. The Analyst. 2000 Dec; 125(12):2230-5. doi: 10.1039/b005743f. [PMID: 11219057]
  • P J van der Merwe, A Pretorius, W Burger. Urinary excretion of diethylstilbestrol in the ostrich. Journal of the South African Veterinary Association. 1998 Jun; 69(2):57-8. doi: 10.4102/jsava.v69i2.816. [PMID: 9760398]
  • G G Kuiper, B Carlsson, K Grandien, E Enmark, J Häggblad, S Nilsson, J A Gustafsson. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology. 1997 Mar; 138(3):863-70. doi: 10.1210/endo.138.3.4979. [PMID: 9048584]
  • O F Vozianov, O H Rieznikov, I O Klymenko, S V Varga, P V Synitsyn, L V Chaĭkovs'ka, S O Vozianov, T Iu Arystova. [The correlation of the hormonal and clinical effects in patients with prostatic cancer undergoing niftolid treatment in combination with low doses of synestrol]. Likars'ka sprava. 1996 Jan; ?(1-2):107-10. doi: NULL. [PMID: 9005063]
  • S K Banerjee, S Banerjee, S A Li, J J Li. Induction of chromosome aberrations in Syrian hamster renal cortical cells by various estrogens. Mutation research. 1994 Dec; 311(2):191-7. doi: 10.1016/0027-5107(94)90176-7. [PMID: 7526183]
  • M D Green, E M Oturu, T R Tephly. Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug metabolism and disposition: the biological fate of chemicals. 1994 Sep; 22(5):799-805. doi: NULL. [PMID: 7835232]
  • H Inano, K Suzuki, H Ishii-Ohba, H Yamanouchi, M Takahashi, K Wakabayashi. Promotive effects of diethylstilbestrol, its metabolite (Z,Z-dienestrol) and a stereoisomer of the metabolite (E,E-dienestrol) in tumorigenesis of rat mammary glands pregnancy-dependently initiated with radiation. Carcinogenesis. 1993 Oct; 14(10):2157-63. doi: 10.1093/carcin/14.10.2157. [PMID: 8222069]
  • D M Ignar-Trowbridge, A R Hughes, J W Putney, J A McLachlan, K S Korach. Diethylstilbestrol stimulates persistent phosphatidylinositol lipid turnover by an estrogen receptor-mediated mechanism in immature mouse uterus. Endocrinology. 1991 Nov; 129(5):2423-30. doi: 10.1210/endo-129-5-2423. [PMID: 1935776]
  • R Bagnati, M G Castelli, L Airoldi, M Paleologo Oriundi, A Ubaldi, R Fanelli. Analysis of diethylstilbestrol, dienestrol and hexestrol in biological samples by immunoaffinity extraction and gas chromatography-negative-ion chemical ionization mass spectrometry. Journal of chromatography. 1990 May; 527(2):267-78. doi: 10.1016/s0378-4347(00)82111-8. [PMID: 2167323]
  • E D Ramsey, J R Perkins, D E Games, J R Startin. Analysis of drug residues in tissue by combined supercritical-fluid extraction-supercritical-fluid chromatography-mass spectrometry-mass spectrometry. Journal of chromatography. 1989 Mar; 464(2):353-64. doi: 10.1016/s0021-9673(00)94253-5. [PMID: 2542348]
  • T D Oberley, L J Lauchner, T D Pugh, A Gonzalez, S Goldfarb, S A Li, J J Li. Specific estrogen-induced cell proliferation of cultured Syrian hamster renal proximal tubular cells in serum-free chemically defined media. Proceedings of the National Academy of Sciences of the United States of America. 1989 Mar; 86(6):2107-11. doi: 10.1073/pnas.86.6.2107. [PMID: 2928320]
  • D Sh Beniashvili, T G Zedginidze. Significance of modifying factors in the development of transplacental renal tumours in rabbits. IARC scientific publications. 1989; ?(96):51-5. doi: NULL. [PMID: 2478464]
  • C J Arts, P T Kemperman, H van den Berg. Oestrogen radioreceptor assay for multi-residue screening of bovine urine for oestrogenic anabolic compounds. Food additives and contaminants. 1989 Jan; 6(1):103-15. doi: 10.1080/02652038909373743. [PMID: 2536336]
  • S P Adams, A C Notides. Reduction of irreversible binding of diethylstilbestrol in hamster renal cortex by inhibitors of cytochrome P-450. Toxicology and applied pharmacology. 1987 Mar; 88(1):113-22. doi: 10.1016/0041-008x(87)90275-4. [PMID: 2436352]
  • A P Carter, J D Cottingham, S N Dixon, R J Heitzman. An improved radioimmunoassay for the anabolic agent hexoestrol, using a monoclonal antibody. Journal of veterinary pharmacology and therapeutics. 1985 Dec; 8(4):362-7. doi: 10.1111/j.1365-2885.1985.tb00968.x. [PMID: 3005606]
  • E H Jansen, R H van den Berg, H van Blitterswijk, R Both-Miedema, R W Stephany. A highly specific detection method for diethylstilbestrol in bovine urine by radioimmunoassay following high performance liquid chromatography. Food additives and contaminants. 1985 Oct; 2(4):271-81. doi: 10.1080/02652038509373556. [PMID: 2998898]
  • J G Liehr, B B DaGue, A M Ballatore. Reactivity of 4',4"-diethylstilbestrol quinone, a metabolic intermediate of diethylstilbestrol. Carcinogenesis. 1985 Jun; 6(6):829-36. doi: 10.1093/carcin/6.6.829. [PMID: 4006069]
  • K Takahashi, L S Jensen. Reduction in hepatic lipid and plasma estradiol in estrogenized chicks injected with ascorbic acid. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1985 Feb; 178(2):200-3. doi: 10.3181/00379727-178-41998. [PMID: 3969379]
  • E H Jansen, R W Stephany. [Diethylstilbestrol in urine of slaughtered cattle]. Tijdschrift voor diergeneeskunde. 1984 May; 109(10):402-4. doi: NULL. [PMID: 6330929]
  • Y Akiba, K Takahashi, T Matsumoto. Effect of diisopropyl 1,3-dithiolan-2-ylidenemalonate on experimental fatty livers in chicks. Poultry science. 1984 Jan; 63(1):117-22. doi: 10.3382/ps.0630117. [PMID: 6701137]
  • Y Akiba, K Takahashi, M Kimura, S I Hirama, T Matsumoto. The influence of environmental temperature, thyroid status and a synthetic oestrogen on the induction of fatty livers in chicks. British poultry science. 1983 Jan; 24(1):71-80. doi: 10.1080/00071668308416715. [PMID: 6831278]
  • R Schade, W Bürger. Hormonal regulation of a new female-specific serum protein (FP) of the laboratory rat. Experientia. 1982 Apr; 38(4):509-11. doi: 10.1007/bf01952667. [PMID: 7084425]
  • A A Zaninovich, R Boado, E Ulloa, N R Bromage, A J Matty. Inhibition of thyroidal iodine release by oestrogens in euthyroid subjects. Acta endocrinologica. 1982 Mar; 99(3):386-92. doi: 10.1530/acta.0.0990386. [PMID: 7072447]
  • A A Zaninovich, R Boado, O Degrossi, N Bromage, A J Matty. Inhibition of thyroidal iodine release by estrogens in patients with hyperthyroidism. The Journal of clinical endocrinology and metabolism. 1979 Oct; 49(4):533-7. doi: 10.1210/jcem-49-4-533. [PMID: 582598]
  • M Metzler. Diethylstilbestrol: evidence for metabolic activation in man, rat, and hamster. National Cancer Institute monograph. 1979 May; ?(51):73-6. doi: NULL. [PMID: 481583]
  • J Weidenfeld, P Carter, V N Reinhold, S B Tanner, L L Engel. Metabolism of diethylstilbestrol: identification of a catechol derived from dienestrol. Biomedical mass spectrometry. 1978 Oct; 5(10):587-90. doi: 10.1002/bms.1200051008. [PMID: 106901]
  • K Pietrzik, C Hesse, D Hötzel. [Residue analysis of substances with estrogenic effects]. DTW. Deutsche tierarztliche Wochenschrift. 1976 May; 83(5):233-6. doi: NULL. [PMID: 776571]
  • D Schnorr, M Mebel, G Dörner, F Stahl, W Rohde. Endocrine effects of oestrogen treatment in patients with prostatic cancer. European urology. 1976; 2(2):85-8. doi: 10.1159/000471968. [PMID: 971678]
  • G Dörner, W Rohde, D Schnorr. Evocability of a slight positive oestrogen feedback action on LH secretion in castrated and oestrogen-primed men. Endokrinologie. 1975 Dec; 66(3):373-6. doi: NULL. [PMID: 174906]
  • R H Roberson, T Trujillo. The effect of methionine, thiouracil, dienestrol diacetate and thyroprotein on the development and prevention of fatty liver in pullets. Poultry science. 1975 May; 54(3):715-21. doi: 10.3382/ps.0540715. [PMID: 1153373]
  • S L TOMPSETT. NOTE ON THE DETECTION OF HEXOESTROL, STILBOESTROL, DIENOESTROL AND THE P-HYDROXY METABOLITES OF PHENOBARBITONE AND PHENYTOIN IN URINE. The Journal of pharmacy and pharmacology. 1964 Mar; 16(?):207-8. doi: 10.1111/j.2042-7158.1964.tb07444.x. [PMID: 14163983]
  • R I POL'KINA. [Renal tumors produced with synestrol and diethylstilbestrol in golden hamsters]. Voprosy onkologii. 1961; 7(7)(?):35-41. doi: NULL. [PMID: 13736651]