Pyricarbate (BioDeep_00000009393)

 

Secondary id: BioDeep_00000858985

human metabolite blood metabolite


代谢物信息卡片


N-methyl[(6-{[(methyl-C-hydroxycarbonimidoyl)oxy]methyl}pyridin-2-yl)methoxy]carboximidic acid

化学式: C11H15N3O4 (253.106251)
中文名称: 吡卡酯
谱图信息: 最多检出来源 Mus musculus(blood) 85.71%

分子结构信息

SMILES: CN=C(O)OCC1=CC=CC(COC(O)=NC)=N1
InChI: InChI=1S/C11H15N3O4/c1-12-10(15)17-6-8-4-3-5-9(14-8)7-18-11(16)13-2/h3-5H,6-7H2,1-2H3,(H,12,15)(H,13,16)

描述信息

C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents
D009676 - Noxae > D000963 - Antimetabolites
Same as: D01396

同义名列表

19 个代谢物同义名

N-methyl[(6-{[(methyl-C-hydroxycarbonimidoyl)oxy]methyl}pyridin-2-yl)methoxy]carboximidic acid; 2,6-Pyridinedimethanol-bis-(N-methylcarbamate); Pyridinol carbamic acid; Pyridinol carbamate; Pyridinolcarbamate; Pyricarbic acid; Colesterinex; Pyricarbate; Parmidine; Prodectin; Angioxine; Duvaline; Anginine; Gasparol; Sospitan; Anginin; Movecil; Lisator; Duaxol



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Qianshen Zhang, Zhiyan Wen, Xin Zhang, Jiajie She, Xiaoling Wang, Zongyu Gao, Ruiqi Wang, Xiaofei Zhao, Zhen Su, Zhen Li, Dawei Li, Xiaofeng Wang, Yongliang Zhang. RETICULON-LIKE PROTEIN B2 is a pro-viral factor co-opted for the biogenesis of viral replication organelles in plants. The Plant cell. 2023 May; ?(?):. doi: 10.1093/plcell/koad146. [PMID: 37216674]
  • Xin Deng, Hong-Yuan Lei, Yong-Shen Ren, Jiao Ai, Yan-Qiu Li, Shuai Liang, Lin-Lin Chen, Mao-Chuan Liao. A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis. Journal of ethnopharmacology. 2023 Jan; 300(?):115677. doi: 10.1016/j.jep.2022.115677. [PMID: 36064148]
  • Akira Hasegawa, Daichi Utsumi, Kaare Lund, Mitsuhiro Okano, Katsuyo Ohashi-Doi, Kimihiro Okubo. Correlation between sensitization to house dust mite major allergens, age, and symptoms in Japanese house dust mite allergic subjects. International immunopharmacology. 2022 Jun; 107(?):108640. doi: 10.1016/j.intimp.2022.108640. [PMID: 35217338]
  • Nenad Joksimović, Jelena Petronijević, Emilija Milović, Nenad Janković, Marijana Kosanić, Nevena Petrović. Antioxidant and Antimicrobial Potential, BSA and DNA Binding Properties of Some 3-Hydroxy-3-Pyrrolin-2-Ones Bearing Thenoyl Fragment. Medicinal chemistry (Shariqah (United Arab Emirates)). 2022; 18(7):784-790. doi: 10.2174/1573406418666220304230342. [PMID: 35249503]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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  • T Tomita, I Yonekura, Y Shirasaki, E Hayashi, F Numano. Effects of phthalazinol (EG 626) and pyridinolcarbamate (Anginin) on lipolytic enzyme activities in rat adipose tissue -in vivo and in vitro-. Japanese journal of pharmacology. 1980 Feb; 30(1):65-73. doi: 10.1254/jjp.30.65. [PMID: 6249948]
  • V Orbetzova, Z Jurukova, M Orbetzova. Antiatherogenic effect of pyridinolcarbamate (prodectin). Experimental study. Artery. 1980; 8(6):560-9. doi: . [PMID: 7259535]
  • H Bouissou, J de Graeve, M Julian, M T Pieraggi, J C Thiers. [Effect of pyridinol carbamate on long-term lathyrism and experimental atheroma in the rat. Histological and biochemical study]. Paroi arterielle. 1980; 6(1):3-15. doi: . [PMID: 7422355]
  • M T Pieraggi, J De Graeve, M Julian, J C Thiers, H Bouissou. Long term lathyrism and atherogenic diet in the rat. Protective action of pyridinol carbamate. Virchows Archiv. A, Pathological anatomy and histology. 1980; 387(1):59-66. doi: 10.1007/bf00428429. [PMID: 7467116]
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  • A S Reddi, W Oppermann, C A Velasco, R A Camerini-Davalos. Diabetic microangiopathy in KK mice. II. Suppression of Glomerulosclerosis by pyridinolcarbamate. Experimental and molecular pathology. 1977 Apr; 26(2):325-39. doi: 10.1016/0014-4800(77)90060-0. [PMID: 852540]
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