jatrorrizine (BioDeep_00000859955)

Main id: BioDeep_00000000088

 

PANOMIX_OTCML-2023


代谢物信息卡片


Jatrorrhizine

化学式: C20H20NO4+ (338.13922600000006)
中文名称: 药根碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC
InChI: InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1

描述信息

同义名列表

4 个代谢物同义名

Jatrorrhizine; iatrorrhizine; jatrorrizine; jatrorhizinc



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lingyu Huang, Yu Sha, Wenken Liang, Chune Mo, Chunhong Li, Yecheng Deng, Weiwei Gong, Xianliang Hou, Minglin Ou. High-throughput sequencing reveals Jatrorrhizine inhibits colorectal cancer growth by ferroptosis-related genes. BMC medical genomics. 2023 Sep; 16(1):217. doi: 10.1186/s12920-023-01619-3. [PMID: 37710311]
  • Tianying Hong, Xianmei Pan, Han Xu, Zhijuan Zheng, Lizhen Wen, Jing Li, Mingfeng Xia. Jatrorrhizine inhibits Piezo1 activation and reduces vascular inflammation in endothelial cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Apr; 163(?):114755. doi: 10.1016/j.biopha.2023.114755. [PMID: 37105072]
  • Huan He, Jianling Deng, Maochun Yang, Linjing An, Xiaoli Ye, Xuegang Li. Jatrorrhizine from Rhizoma Coptidis exerts an anti-obesity effect in db/db mice. Journal of ethnopharmacology. 2022 Nov; 298(?):115529. doi: 10.1016/j.jep.2022.115529. [PMID: 35835345]
  • Yan Zhou, Yuehan Wang, Chi Teng Vong, Yanyan Zhu, Baojun Xu, Cheng-Chao Ruan, Yitao Wang, Wai San Cheang. Jatrorrhizine Improves Endothelial Function in Diabetes and Obesity through Suppression of Endoplasmic Reticulum Stress. International journal of molecular sciences. 2022 Oct; 23(20):. doi: 10.3390/ijms232012064. [PMID: 36292919]
  • Janiqua Rolle, Dorothy O Asante, Linsey L Kok-Fong, Hamza Boucetta, Theodora A Seidu, Lesieli L K Tai, Raphael N Alolga. Jatrorrhizine: a review of its pharmacological effects. The Journal of pharmacy and pharmacology. 2021 Apr; 73(6):709-719. doi: 10.1093/jpp/rgaa065. [PMID: 33822109]
  • Dong-Jun Fu, Jun Li, Bin Yu. Annual review of LSD1/KDM1A inhibitors in 2020. European journal of medicinal chemistry. 2021 Mar; 214(?):113254. doi: 10.1016/j.ejmech.2021.113254. [PMID: 33581557]
  • Pooja M, Gangavaram Jyothi Reddy, Kanipakam Hema, Sujatha Dodoala, Bharathi Koganti. Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies. European journal of pharmacology. 2021 Jan; 890(?):173688. doi: 10.1016/j.ejphar.2020.173688. [PMID: 33130280]
  • Chu Chu, Linmin Lian, Caijing Liu, Jing Li, Hui Mao, Luyi Jiang, Jizhong Yan. Online preconcentration by electrokinetic supercharging for sensitive determination of berberine and jatrorrhizine in biological samples. Biomedical chromatography : BMC. 2020 Jun; 34(6):e4824. doi: 10.1002/bmc.4824. [PMID: 32154596]
  • Guanji Wu, Ting Mu, Lihong Zhang, Xiaolin Chen. Jatrorrhizine Hydrochloride alleviates tert-butyl hydroperoxide-induced endothelial cell injury through its anti-inflammatory activity and PPAR-γ activation. Cellular and molecular biology (Noisy-le-Grand, France). 2020 May; 66(2):125-129. doi: 10.14715/cmb/2020.66.2.20. [PMID: 32415938]
  • Rui-Feng Liang, Wen-Jing Ge, Xian-Mei Song, Jun-Ping Zhang, Wei-Feng Cui, She-Feng Zhang, Geng-Sheng Li. Involvement of organic anion-transporting polypeptides and organic cation transporter in the hepatic uptake of jatrorrhizine. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Apr; 50(4):479-487. doi: 10.1080/00498254.2019.1651921. [PMID: 31368836]
  • Juanjuan Liu, Qianqian Li, Changzhong Wang, Jing Shao, Tianming Wang, Daqiang Wu, Kelong Ma, Guiming Yan, Dengke Yin. Antifungal evaluation of traditional herbal monomers and their potential for inducing cell wall remodeling in Candida albicans and Candida auris. Biofouling. 2020 03; 36(3):319-331. doi: 10.1080/08927014.2020.1759559. [PMID: 32410461]
  • Sheng Wang, Wei Jiang, Ting Ouyang, Xiu-Yin Shen, Fen Wang, Yu-Hua Qu, Min Zhang, Tao Luo, Hua-Qiao Wang. Jatrorrhizine Balances the Gut Microbiota and Reverses Learning and Memory Deficits in APP/PS1 transgenic mice. Scientific reports. 2019 12; 9(1):19575. doi: 10.1038/s41598-019-56149-9. [PMID: 31862965]
  • Siyuan Sun, Sisi Zhou, Shaowei Lei, Shujie Zhu, Kai Wang, Huidi Jiang, Hui Zhou. Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice. Xenobiotica; the fate of foreign compounds in biological systems. 2019 Oct; 49(10):1237-1243. doi: 10.1080/00498254.2018.1542188. [PMID: 30472912]
  • Zhong-Min Zhao, Xiao-Fei Shang, Raymond Kobla Lawoe, Ying-Qian Liu, Rui Zhou, Yu Sun, Yin-Fang Yan, Jun-Cai Li, Guan-Zhou Yang, Cheng-Jie Yang. Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine. Pesticide biochemistry and physiology. 2019 Sep; 159(?):51-58. doi: 10.1016/j.pestbp.2019.05.015. [PMID: 31400784]
  • Qi Li, Huan DU, Huan-Song Wen, Tong Xu, Yu-Jie Wang, Xian-Rong Lai, Gang Fan. [Determination of six compounds in Berberidis Cortex and comparative study of its different species]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2019 Mar; 44(5):968-974. doi: 10.19540/j.cnki.cjcmm.20181226.014. [PMID: 30989857]
  • Shizuka Kamimura, Masakazu Nishihara, Yuko Osumi, Hironori Shiota. [Simultaneous Quantitative Analysis of Berberine and Other Alkaloids in Powdered Phellodendron Bark]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2019; 139(11):1471-1478. doi: 10.1248/yakushi.19-00097. [PMID: 31685744]
  • Xinyu Zhao, Yan Wang, Lu Zheng, Chengpeng Sun, Chao Wang, Haijian Cong, Ting Xiang, Lin Zhang, Houli Zhang, Sa Deng, Baojing Zhang, Bin Wu, Xiaokui Huo. Comparative pharmacokinetics study of five alkaloids in rat plasma and related compound-herb interactions mechanism after oral administration of Shuanghua Baihe tablets. Natural product research. 2018 Sep; 32(17):2031-2036. doi: 10.1080/14786419.2017.1365075. [PMID: 28871816]
  • Tian-Jin Wu, Jun Lu, Hui Ni, Ping Li, Yan Jiang, Hui-Jun Li. Construction of an optimized method for quality evaluation and species discrimination of Coptidis Rhizoma by ion-pair high performance liquid chromatography combined with response surface methodology. Journal of pharmaceutical and biomedical analysis. 2018 May; 153(?):152-157. doi: 10.1016/j.jpba.2018.02.019. [PMID: 29494887]
  • Xiaoling Gu, Yang Jin, Fang Dong, Yueqing Cai, Zhengyi You, Junhui You, Liying Zhang, Shuhu Du. Toward rapid analysis, forecast and discovery of bioactive compounds from herbs by jointly using thin layer chromatography and ratiometric surface-enhanced Raman spectroscopy technique. Journal of pharmaceutical and biomedical analysis. 2018 May; 153(?):9-15. doi: 10.1016/j.jpba.2018.02.016. [PMID: 29459236]
  • Shui-Lan Zhu, Ting Lei, Xu Gao, Jun Tu. [Jatrorrhizine regulates GLUTs with multiple manners for hypoglycemic effect in insulin-resistance 3T3-L1 adipocytes]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2018 Mar; 43(6):1215-1220. doi: 10.19540/j.cnki.cjcmm.20180104.005. [PMID: 29676131]
  • Xuelin Zhou, Haotian Li, Zhilong Shi, Sijia Gao, Shizhang Wei, Kun Li, Jiabo Wang, Jianyu Li, Ruilin Wang, Man Gong, Yanling Zhao, Xiaohe Xiao. Inhibition activity of a traditional Chinese herbal formula Huang-Lian-Jie-Du-Tang and its major components found in its plasma profile on neuraminidase-1. Scientific reports. 2017 Nov; 7(1):15549. doi: 10.1038/s41598-017-15733-7. [PMID: 29138445]
  • Jing-Yu Zheng, Guo-Feng Li, Zhong-Mei He, Hong-Yan Zhu, Yan Zhao, Yu-Gang Gao, He Yang, Lian-Xue Zhang. [Pharmacokinetics and oral bioavailability of palmatine and jatrorrhizine in Huangteng in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2017 Jul; 42(14):2773-2778. doi: 10.19540/j.cnki.cjcmm.20170523.002. [PMID: 29098836]
  • Tao Luo, Xiu-Yin Shen, Sheng Li, Ting Ouyang, Quan-An Mai, Hua-Qiao Wang. The Protective Effect of Jatrorrhizine Against Oxidative Stress in Primary Rat Cortical Neurons. CNS & neurological disorders drug targets. 2017; 16(5):617-623. doi: 10.2174/1871527315666160711101210. [PMID: 27401065]
  • Weiwei Yang, Liping She, Kun Yu, Shan Yan, Xuefeng Zhang, Xiaoyi Tian, Shuren Ma, Xiwen Zhang. Jatrorrhizine hydrochloride attenuates hyperlipidemia in a high-fat diet-induced obesity mouse model. Molecular medicine reports. 2016 Oct; 14(4):3277-84. doi: 10.3892/mmr.2016.5634. [PMID: 27573054]
  • Liping Li, Siyuan Sun, Yayun Weng, Feifeng Song, Sisi Zhou, Mengru Bai, Hui Zhou, Su Zeng, Huidi Jiang. Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3. Xenobiotica; the fate of foreign compounds in biological systems. 2016; 46(2):175-83. doi: 10.3109/00498254.2015.1056283. [PMID: 26134304]
  • Wenguang Wang, Xiaoli Ma, Xiaoyu Guo, Mingbo Zhao, Pengfei Tu, Yong Jiang. A series of strategies for solving the shortage of reference standards for multi-components determination of traditional Chinese medicine, Mahoniae Caulis as a case. Journal of chromatography. A. 2015 Sep; 1412(?):100-11. doi: 10.1016/j.chroma.2015.08.015. [PMID: 26298606]
  • Raphael N Alolga, Yong Fan, Gang Zhang, Jin Li, Yi-Jing Zhao, Jimmy Lelu Kakila, Yan Chen, Ping Li, Lian-Wen Qi. Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers. Scientific reports. 2015 Aug; 5(?):12961. doi: 10.1038/srep12961. [PMID: 26268432]
  • Jiawei Meng, Wenpeng Zhang, Tao Bao, Zilin Chen. Novel molecularly imprinted magnetic nanoparticles for the selective extraction of protoberberine alkaloids in herbs and rat plasma. Journal of separation science. 2015 Jun; 38(12):2117-25. doi: 10.1002/jssc.201500264. [PMID: 25832420]
  • Hao Wu, Kai He, YanZhi Wang, DongFang Xue, Na Ning, Zongyao Zou, Xiaoli Ye, Xuegang Li, DeZhen Wang, Jie Pang. The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2014 Sep; 21(11):1373-81. doi: 10.1016/j.phymed.2014.05.002. [PMID: 24894270]
  • Zhuo Ye, Yinfeng Li, Jianguo Wen, Kunjing Li, Baoxian Ye. Study of the voltammetric behavior of jatrorrhizine and its sensitive determination at electrochemical pretreatment glassy carbon electrode. Talanta. 2014 Aug; 126(?):38-45. doi: 10.1016/j.talanta.2014.03.026. [PMID: 24881532]
  • Junfen Li, Jinzeng Li, Yong Jiao, Chuan Dong. Spectroscopic analysis and molecular modeling on the interaction of jatrorrhizine with human serum albumin (HSA). Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2014 Jan; 118(?):48-54. doi: 10.1016/j.saa.2013.07.029. [PMID: 24036307]
  • Ran Mi, Yan-Jun Hu, Xiao-Yang Fan, Yu Ouyang, Ai-Min Bai. Exploring the site-selective binding of jatrorrhizine to human serum albumin: spectroscopic and molecular modeling approaches. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2014 Jan; 117(?):163-9. doi: 10.1016/j.saa.2013.08.013. [PMID: 23988532]
  • Yan Zhou, Shijie Cao, Ying Wang, Peixiang Xu, Jiankun Yan, Wen Bin, Feng Qiu, Ning Kang. Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells. Fitoterapia. 2014 Jan; 92(?):230-7. doi: 10.1016/j.fitote.2013.11.010. [PMID: 24321576]
  • Zhao-Tang Ma, Xiu-Wei Yang, Ying Zhang, Jian-Xun Liu. Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction. Journal of Asian natural products research. 2014; 16(5):483-96. doi: 10.1080/10286020.2014.913577. [PMID: 24797560]
  • Ran Mi, Pei-Qi Li, Yan-Jun Hu, Xiao-Yang Fan, Hai-Ying Li, Xue-Cheng Yu, Yu Ouyang. Biophysical studies on the interactions of jatrorrhizine with bovine serum albumin by spectroscopic and molecular modeling methods. Molecular biology reports. 2013 Jul; 40(7):4397-404. doi: 10.1007/s11033-013-2529-z. [PMID: 23645029]
  • Hui Zhou, Rong Shi, Bingliang Ma, Yueming Ma, Changhong Wang, Dazheng Wu, Xinhong Wang, Nengneng Cheng. CYP450 1A2 and multiple UGT1A isoforms are responsible for jatrorrhizine metabolism in human liver microsomes. Biopharmaceutics & drug disposition. 2013 Apr; 34(3):176-85. doi: 10.1002/bdd.1835. [PMID: 23299247]
  • Zhaodan Tan, Rong Zhu, Rong Shi, Jie Zhong, Yueming Ma, Changhong Wang, Xinhong Wang, Nengneng Cheng. Involvement of rat organic cation transporter 2 in the renal uptake of jatrorrhizine. Journal of pharmaceutical sciences. 2013 Apr; 102(4):1333-42. doi: 10.1002/jps.23432. [PMID: 23280813]
  • Shuping Wang, Lei Liu, Lingling Wang, Peng Jiang, Li Xiang, Weidong Zhang, Runhui Liu. Development and validation of liquid chromatography-tandem mass spectrometry method for simultaneous determination of four tertiary alkaloids in rat plasma and its application to a pharmacokinetic study. Journal of pharmaceutical and biomedical analysis. 2013 Jan; 72(?):80-8. doi: 10.1016/j.jpba.2012.09.001. [PMID: 23146230]
  • Xiang-Shan Tan, Jing-Yi Ma, Ru Feng, Chao Ma, Wen-Jing Chen, Yu-Peng Sun, Jie Fu, Min Huang, Chi-Yu He, Jia-Wen Shou, Wen-Yi He, Yan Wang, Jian-Dong Jiang. Tissue distribution of berberine and its metabolites after oral administration in rats. PloS one. 2013; 8(10):e77969. doi: 10.1371/journal.pone.0077969. [PMID: 24205048]
  • Rui An, Hua Zhang, Yi-Zhu Zhang, Ran-Chi Xu, Xin-Hong Wang. [Intestinal absorption of different combinations of active compounds from Gegenqinlian decoction by rat single pass intestinal perfusion in situ]. Yao xue xue bao = Acta pharmaceutica Sinica. 2012 Dec; 47(12):1696-702. doi: ". [PMID: 23460978]
  • Xinfeng Zhao, Qian Li, Liujiao Bian, Xiaohui Zheng, Jianbin Zheng, Youyi Zhang, Zijian Li. Using immobilized G-protein coupled receptors to screen bioactive traditional Chinese medicine compounds with multiple targets. Journal of pharmaceutical and biomedical analysis. 2012 Nov; 70(?):549-52. doi: 10.1016/j.jpba.2012.05.004. [PMID: 22651959]
  • Gang Fan, Meng Ying Zhang, Xiang Dong Zhou, Xian Rong Lai, Qing Hong Yue, Ce Tang, Wei Zao Luo, Yi Zhang. Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy. Analytica chimica acta. 2012 Oct; 747(?):76-83. doi: 10.1016/j.aca.2012.08.038. [PMID: 22986138]
  • Shuaihua Zhang, Ruiyang Ma, Xiumin Yang, Chun Wang, Zhi Wang. On-line sample concentration and determination of cationic alkaloids in human plasma by micelle to solvent stacking in capillary zone electrophoresis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Oct; 906(?):41-7. doi: 10.1016/j.jchromb.2012.08.017. [PMID: 22944006]
  • Mayurkumar B Patel, Shrihari Mishra. Isoquinoline alkaloids from Tinospora cordifolia inhibit rat lens aldose reductase. Phytotherapy research : PTR. 2012 Sep; 26(9):1342-7. doi: 10.1002/ptr.3721. [PMID: 22294283]
  • Yonghong Zhu, Ling Tong, Shuiping Zhou, He Sun, Kaishun Bi, Boli Zhang. Simultaneous determination of active flavonoids and alkaloids of Tang-Min-Ling-Pill in rat plasma by liquid chromatography tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Sep; 904(?):51-8. doi: 10.1016/j.jchromb.2012.07.010. [PMID: 22883103]
  • Lihong Liu, Zilin Chen. Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection. Analytica chimica acta. 2012 Aug; 737(?):99-104. doi: 10.1016/j.aca.2012.05.054. [PMID: 22769040]
  • Ling Zhu, Bo Huang, Xiaoquan Ban, Jingsheng He, Yuxin Chen, Li Han, Youwei Wang. Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC-MS analysis of its chemical composition. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012 Jul; 50(7):2584-8. doi: 10.1016/j.fct.2012.04.035. [PMID: 22561681]
  • Jin Ah Ryuk, Ming Shan Zheng, Mi Young Lee, Chang Seob Seo, Ying Li, Seung Ho Lee, Dong Cheul Moon, Hye Won Lee, Je-Hyun Lee, Ju Young Park, Jong Keun Son, Byoung Seob Ko. Discrimination of Phellodendron amurense and P. chinense based on DNA analysis and the simultaneous analysis of alkaloids. Archives of pharmacal research. 2012 Jun; 35(6):1045-54. doi: 10.1007/s12272-012-0612-y. [PMID: 22870814]
  • Jin Yuan, Ying Wang, Rui An, Shuang Wang, Shui-Jun Li, Jing-Ying Jia, S W Annie Bligh, Xin-Hong Wang, Yue-Ming Ma. Simultaneous determination of six alkaloids and one monoterpene in rat plasma by liquid chromatography-tandem mass spectrometry and pharmacokinetic study after oral administration of a Chinese medicine Wuji Pill. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 May; 895-896(?):154-61. doi: 10.1016/j.jchromb.2012.03.036. [PMID: 22503734]
  • Rong Shi, Hui Zhou, Bingliang Ma, Yueming Ma, Dazheng Wu, Xinhong Wang, Hongfeng Luo, Nengneng Cheng. Pharmacokinetics and metabolism of jatrorrhizine, a gastric prokinetic drug candidate. Biopharmaceutics & drug disposition. 2012 Apr; 33(3):135-45. doi: 10.1002/bdd.1779. [PMID: 22344858]
  • Beibei Zhang, Aili Cao, Jiyan Zhou, Zhibi Hu, Dazheng Wu. Effect of jatrorrhizine on delayed gastrointestinal transit in rat postoperative ileus. The Journal of pharmacy and pharmacology. 2012 Mar; 64(3):413-9. doi: 10.1111/j.2042-7158.2011.01407.x. [PMID: 22309273]
  • Fengqing Liu, Zhongdong Li, Xiaojin Shi, Mingkang Zhong. Determination of berberine, palmatine and jatrorrhizine in rabbit plasma by liquid chromatography-electrospray ionization-mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2011 Dec; 56(5):1006-15. doi: 10.1016/j.jpba.2011.08.001. [PMID: 21890297]
  • Stephen Cw Sze, Ho-Pan Cheung, Tzi-Bun Ng, Zhang-Jing Zhang, Kam-Lok Wong, Hei-Kiu Wong, Yong-Mei Hu, Christine Mn Yow, Yao Tong. Effects of Erxian decoction, a Chinese medicinal formulation, on serum lipid profile in a rat model of menopause. Chinese medicine. 2011 Nov; 6(?):40. doi: 10.1186/1749-8546-6-40. [PMID: 22047073]
  • Ji Zhang, Hang Jin, Wanyi Li, Yuanzhong Wang, Jinyu Zhang. [Correlation analysis soil nutrition as sell as yield and active compounds of Coptis teeta]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Oct; 36(19):2629-31. doi: 10.4268/cjcmm20111906. [PMID: 22242419]
  • Mayurkumar B Patel, Shrihari Mishra. Hypoglycemic activity of alkaloidal fraction of Tinospora cordifolia. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2011 Sep; 18(12):1045-52. doi: 10.1016/j.phymed.2011.05.006. [PMID: 21665451]
  • Juan Chen, Yang Yang, Yan-Ping Shi. Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. Biomedical chromatography : BMC. 2011 Sep; 25(9):1045-53. doi: 10.1002/bmc.1569. [PMID: 21154891]
  • JianYe Yuan, JiYan Zhou, ZhiBi Hu, Guang Ji, JianQun Xie, DaZheng Wu. The effects of jatrorrhizine on contractile responses of rat ileum. European journal of pharmacology. 2011 Aug; 663(1-3):74-9. doi: 10.1016/j.ejphar.2011.05.002. [PMID: 21596029]
  • Hao Wu, Li-Bing Zhang, Li-Ming Du. Ionic liquid sensitized fluorescence determination of four isoquinoline alkaloids. Talanta. 2011 Jul; 85(1):787-93. doi: 10.1016/j.talanta.2011.04.076. [PMID: 21645774]
  • Tao Luo, Hui Zhang, Wei-Wei Zhang, Jun-Ting Huang, En-Lin Song, Sheng-Guo Chen, Feng He, Jie Xu, Hua-Qiao Wang. Neuroprotective effect of Jatrorrhizine on hydrogen peroxide-induced cell injury and its potential mechanisms in PC12 cells. Neuroscience letters. 2011 Jul; 498(3):227-31. doi: 10.1016/j.neulet.2011.05.017. [PMID: 21605627]
  • Bin Zan, Rong Shi, Tianming Wang, Jiasheng Wu, Yueming Ma, Nengneng Cheng. Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics. Biomedical chromatography : BMC. 2011 Jul; 25(7):816-26. doi: 10.1002/bmc.1521. [PMID: 20872909]
  • Chi-Sheng Shia, Yu-Chi Hou, Shin-Hun Juang, Shang-Yuan Tsai, Pei-Hsun Hsieh, Lu-Ching Ho, Pei-Dawn Lee Chao. Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):721293. doi: 10.1093/ecam/nep124. [PMID: 19737807]
  • Chunmei Liu, Yuping Tang, Yongqing Hua, Erxin Shang, Jinao Duan, Dekang Wu, Anwei Ding. [Bio-activity evaluation of Qinlian Siwu decoction on inhibiting mice uterine contraction in vitro and its components analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Dec; 35(24):3362-7. doi: . [PMID: 21438408]
  • Jin Feng, Wen Xu, Xia Tao, Hua Wei, Fei Cai, Bo Jiang, Wansheng Chen. Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. Journal of pharmaceutical and biomedical analysis. 2010 Nov; 53(3):591-8. doi: 10.1016/j.jpba.2010.04.002. [PMID: 20430560]
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