Allicin (BioDeep_00000000766)

   

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Diallyldisulfid-S-oxid, 3-prop-2-enylsulfinylsulfanylprop-1-ene

化学式: C6H10OS2 (162.0173)
中文名称: 蒜素, 大蒜素
谱图信息: 最多检出来源 Viridiplantae(plant) 17.22%

分子结构信息

SMILES: C=CCS(SCC=C)=O
InChI: InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2

描述信息

Allicin is found in garden onion. Allicin is isolated from garlic (Allium sativum). Nutriceutical Allicin is an organic compound obtained from garlic. It is also obtainable from onions, and other species in the family Alliaceae. It was first isolated and studied in the laboratory by Chester J. Cavallito in 1944. This colourless liquid has a distinctively pungent smell. This compound exhibits antibacterial and anti-fungal properties. Allicin is garlics defence mechanism against attacks by pests
Allicin is a sulfoxide and a botanical anti-fungal agent. It has a role as an antibacterial agent.
Allicin has been used in trials studying the treatment of Follicular Lymphoma.
Allicin is a natural product found in Allium chinense, Allium nutans, and other organisms with data available.
See also: Garlic (part of).
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D020011 - Protective Agents > D000975 - Antioxidants
Isolated from garlic (Allium sativum). Nutriceutical
D009676 - Noxae > D000963 - Antimetabolites
D000890 - Anti-Infective Agents
D007004 - Hypoglycemic Agents
Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98\\% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains[1][2].
Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98\% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains[1][2].

同义名列表

50 个代谢物同义名

Diallyldisulfid-S-oxid, 3-prop-2-enylsulfinylsulfanylprop-1-ene; Diallyl thiosulfinate and Allylthiosulphinic acid allyl ester; 2-Propene-1-sulfinothioic acid, S-2-propenyl ester (9CI); 2-Propene-1-sulphinothioic acid S-2-propenyl ester; 2-Propene-1-sulfinothioic acid, S-2-propenyl ester; 2-Propene-1-sulfinothioic acid S-2-propenyl ester; 2-Propene-1-sulfinic acid, thio-, S-allyl ester; 2-Propene-1-sulphinothioate S-2-propenyl ester; 2-Propene-1-sulfinothioate S-2-propenyl ester; 3-[(prop-2-ene-1-sulfinyl)sulfanyl]prop-1-ene; Thio-2-propene-1-sulphinic acid S-allyl ester; thio-2-propene-1-sulfinic acid S-allyl ester; S-2-Propenyl 2-propene-1-sulfinothioate, 9CI; S-prop-2-en-1-yl prop-2-ene-1-sulfinothioate; 4-04-00-00007 (Beilstein Handbook Reference); S-2-PROPEN-1-YL 2-PROPENE-1-SULFINOTHIOATE; Thio-2-propene-1-sulphinate S-allyl ester; Thio-2-propene-1-sulfinate S-allyl ester; 3-prop-2-enylsulfinylsulfanylprop-1-ene; ALLICIN (CONSTITUENT OF GARLIC) [DSC]; 3-(prop-2-enylsulfinylthio)-1-propene; allylthiosulphinic acid allyl ester; S-allyl prop-2-ene-1-sulfinothioate; S-allyl 2-propene-1-sulfinothioate; 3-allylsulfinylsulfanyl-prop-1-ene; 3-allylsulfinylsulfanylprop-1-ene; S-Allyl acrylo-1-sulphinothioate; ALLICIN (CONSTITUENT OF GARLIC); JDLKFOPOAOFWQN-UHFFFAOYSA-N; Allicin (Allyl-S(O)S-Allyl); Dianyctrsnlgide;Allisatin; Diallyldisulfid-S-oxide; diallyl disulfide-oxide; Allicin (not validated); Diallyldisulfid-S-oxid; Diallyl thiosulfinate; Allicin, tech. grade; ALLICIN(TECH GRADE); allylthiosulfinate; ALLICIN [WHO-DD]; UNII-3C39BY17Y6; ALLICIN [MI]; Allicin kit; 3C39BY17Y6; allitridi; C6H10OS2; Allicin; allimin; DADSO; Allicin



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(2)

代谢反应

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(2)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

66 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 AKT1, CASP3, CASP9, HPGDS, MTOR, NFE2L2, NLRP3, NOS3, PIK3CA, PIK3R6, STAT3, TLR4, TP53, VEGFA
Peripheral membrane protein 3 ACHE, MTOR, PIK3R6
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 1 MTOR
Nucleus 12 ACHE, AKT1, CASP3, CASP9, MPO, MTOR, NFE2L2, NLRP3, NOS3, STAT3, TP53, VEGFA
cytosol 14 AKT1, CASP3, CASP9, GPT, GSR, HPGDS, MTOR, NFE2L2, NLRP3, NOS3, PIK3CA, PIK3R6, STAT3, TP53
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 2 NFE2L2, TP53
nucleoplasm 9 AKT1, CASP3, HPGDS, MPO, MTOR, NFE2L2, NOS3, STAT3, TP53
RNA polymerase II transcription regulator complex 2 NFE2L2, STAT3
Cell membrane 5 ACHE, AKT1, PIK3R6, TLR4, TRPA1
Cytoplasmic side 1 MTOR
lamellipodium 2 AKT1, PIK3CA
Multi-pass membrane protein 1 TRPA1
Golgi apparatus membrane 2 MTOR, NLRP3
Synapse 1 ACHE
cell cortex 1 AKT1
cell surface 3 ACHE, TLR4, VEGFA
glutamatergic synapse 2 AKT1, CASP3
Golgi apparatus 4 ACHE, NFE2L2, NOS3, VEGFA
Golgi membrane 3 MTOR, NLRP3, NOS3
lysosomal membrane 1 MTOR
neuromuscular junction 1 ACHE
neuronal cell body 1 CASP3
postsynapse 1 AKT1
Cytoplasm, cytosol 2 NFE2L2, NLRP3
Lysosome 2 MPO, MTOR
plasma membrane 9 ACHE, AKT1, NFE2L2, NOS3, PIK3CA, PIK3R6, STAT3, TLR4, TRPA1
Membrane 9 ACHE, AKT1, MTOR, NLRP3, PIK3R6, TLR4, TP53, TRPA1, VEGFA
axon 1 CCK
caveola 1 NOS3
extracellular exosome 3 GPT, GSR, MPO
Lysosome membrane 1 MTOR
endoplasmic reticulum 3 NLRP3, TP53, VEGFA
extracellular space 4 ACHE, CCK, MPO, VEGFA
perinuclear region of cytoplasm 4 ACHE, NOS3, PIK3CA, TLR4
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
mitochondrion 4 CASP9, GSR, NLRP3, TP53
protein-containing complex 3 AKT1, CASP9, TP53
intracellular membrane-bounded organelle 2 HPGDS, MPO
Microsome membrane 1 MTOR
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 TLR4
Secreted 4 ACHE, CCK, NLRP3, VEGFA
extracellular region 5 ACHE, CCK, MPO, NLRP3, VEGFA
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 GSR, TP53
Extracellular side 1 ACHE
transcription regulator complex 2 STAT3, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
external side of plasma membrane 2 GSR, TLR4
Secreted, extracellular space, extracellular matrix 1 VEGFA
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
Early endosome 1 TLR4
cell-cell junction 1 AKT1
vesicle 1 AKT1
Cytoplasm, cytoskeleton 1 TP53
spindle 1 AKT1
extracellular matrix 1 VEGFA
basement membrane 1 ACHE
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 2 MPO, VEGFA
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
ciliary basal body 1 AKT1
chromatin 3 NFE2L2, STAT3, TP53
mediator complex 1 NFE2L2
stereocilium bundle 1 TRPA1
phagocytic cup 1 TLR4
cytoskeleton 1 NOS3
Lipid-anchor, GPI-anchor 1 ACHE
site of double-strand break 1 TP53
nuclear envelope 1 MTOR
Endomembrane system 2 MTOR, NLRP3
microtubule organizing center 1 NLRP3
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
side of membrane 1 ACHE
germ cell nucleus 1 TP53
replication fork 1 TP53
azurophil granule 1 MPO
lipopolysaccharide receptor complex 1 TLR4
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 2 PIK3CA, PIK3R6
phosphatidylinositol 3-kinase complex, class IA 2 PIK3CA, PIK3R6
endocytic vesicle membrane 1 NOS3
azurophil granule lumen 1 MPO
apoptosome 1 CASP9
phagocytic vesicle lumen 1 MPO
[Isoform 1]: Nucleus 1 TP53
synaptic cleft 1 ACHE
protein-DNA complex 1 NFE2L2
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, phagosome 1 MTOR
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform H]: Cell membrane 1 ACHE
phosphatidylinositol 3-kinase complex, class IB 2 PIK3CA, PIK3R6
caspase complex 1 CASP9


文献列表

  • Wamidh H Talib, Media Mohammed Baban, Aya O Azzam, Jenan J Issa, Alaa Y Ali, Alia Kh AlSuwais, Sana Allala, Lina T Al Kury. Allicin and Cancer Hallmarks. Molecules (Basel, Switzerland). 2024 Mar; 29(6):. doi: 10.3390/molecules29061320. [PMID: 38542956]
  • Christina Schier, Martin C H Gruhlke, Georg Reucher, Alan J Slusarenko, Lothar Rink. Combating Black Fungus: Using Allicin as a Potent Antifungal Agent against Mucorales. International journal of molecular sciences. 2023 Dec; 24(24):. doi: 10.3390/ijms242417519. [PMID: 38139348]
  • Liu-Qing Sun, Chao-Feng Zhu, Jiang-Qin He. Effect of Grape Seed Procyanidins Combined with Allicin on Lipid Levels in Hyperlipidemic Rats. Studies in health technology and informatics. 2023 Nov; 308(?):130-136. doi: 10.3233/shti230833. [PMID: 38007734]
  • Hatice Kubra Sasmaz, Eda Adal, Pınar Kadiroğlu, Serkan Selli, Turkan Uzlasir, Hasim Kelebek. Optimization of complex coacervation parameters for the production of encapsulated black garlic using response surface methodology. Journal of food science. 2023 Oct; ?(?):. doi: 10.1111/1750-3841.16768. [PMID: 37786327]
  • George P Burton, Thomas A K Prescott, Rui Fang, Mark A Lee. Regional variation in the antibacterial activity of a wild plant, wild garlic (Allium ursinum L.). Plant physiology and biochemistry : PPB. 2023 Sep; 202(?):107959. doi: 10.1016/j.plaphy.2023.107959. [PMID: 37619271]
  • Fangyuan Sun, Kailiang Xu, Jiayi Zhou, Wei Zhang, Guihe Duan, Ming Lei. Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways. BMC cardiovascular disorders. 2023 08; 23(1):410. doi: 10.1186/s12872-023-03442-1. [PMID: 37596540]
  • Faris J Alyasiri, Maryam Ghobeh, Masoud Homayouni Tabrizi. Preparation and Characterization of Allicin-Loaded Solid Lipid Nanoparticles Surface-Functionalized with Folic Acid-Bonded Chitosan: In Vitro Anticancer and Antioxidant Activities. Frontiers in bioscience (Landmark edition). 2023 07; 28(7):135. doi: 10.31083/j.fbl2807135. [PMID: 37525919]
  • Ying Yang, Min Li, Hai-Yan Bao, Xin-Xia Li, Jian-Guang Li. [Advances in cardiovascular protection effects and mechanisms of allicin]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jul; 48(13):3409-3420. doi: 10.19540/j.cnki.cjcmm.20230320.601. [PMID: 37474979]
  • Lingjuan Kong, Xiaoqing Ji, Yan Liu, YingJie Du. Effect of artemisinin combined with allicin on improving cardiac function, fibrosis and NF-κB signaling pathway in rats with diabetic cardiomyopathy. Acta biochimica Polonica. 2023 Jun; 70(2):401-405. doi: 10.18388/abp.2020_6692. [PMID: 37307593]
  • Ioana Andreea Barbu, Alexandra Ciorîță, Rahela Carpa, Augustin Catalin Moț, Anca Butiuc-Keul, Marcel Pârvu. Phytochemical Characterization and Antimicrobial Activity of Several Allium Extracts. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28103980. [PMID: 37241721]
  • Ningning Xu, Weinan Han, Guoping Yun, Lulu Shi. Allicin Protects Renal Function, Improves Oxidative Stress and Lipid Peroxidation in Rats with Chronic Renal Failure. Iranian journal of kidney diseases. 2023 May; 17(3):135-140. doi: . [PMID: 37337797]
  • JeongWoo Kang, HyunYoung Chae, Md Akil Hossain. Poultry red mite eradication potential of ivermectin and allicin combination treatment. Veterinary medicine and science. 2023 05; 9(3):1292-1296. doi: 10.1002/vms3.1136. [PMID: 37018122]
  • Penghui Ai, Jundong Xue, Yifei Zhu, Wenchao Tan, Yifei Wu, Ying Wang, Zhongai Li, Zhongya Shi, Dongru Kang, Haoyi Zhang, Liwen Jiang, Zicheng Wang. Comparative analysis of two kinds of garlic seedings: qualities and transcriptional landscape. BMC genomics. 2023 Feb; 24(1):87. doi: 10.1186/s12864-023-09183-x. [PMID: 36829121]
  • Shiyin Xu, Yuxiao Liao, Qi Wang, Liegang Liu, Wei Yang. Current studies and potential future research directions on biological effects and related mechanisms of allicin. Critical reviews in food science and nutrition. 2023; 63(25):7722-7748. doi: 10.1080/10408398.2022.2049691. [PMID: 35293826]
  • Uzair Ali, Martin Wabitsch, Daniel Tews, Monica Colitti. Effects of allicin on human Simpson-Golabi-Behmel syndrome cells in mediating browning phenotype. Frontiers in endocrinology. 2023; 14(?):1141303. doi: 10.3389/fendo.2023.1141303. [PMID: 36936145]
  • Linzehao Li, Qinghe Song, Xiandang Zhang, Yan Yan, Xiaolei Wang. Allicin Alleviates Diabetes Mellitus by Inhibiting the Formation of Advanced Glycation End Products. Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27248793. [PMID: 36557926]
  • Verena Nadin Fritsch, Vu Van Loi, Benno Kuropka, Martin Gruhlke, Christoph Weise, Haike Antelmann. The MarR/DUF24-Family QsrR Repressor Senses Quinones and Oxidants by Thiol Switch Mechanisms in Staphylococcus aureus. Antioxidants & redox signaling. 2022 Nov; ?(?):. doi: 10.1089/ars.2022.0090. [PMID: 36242097]
  • Nan Sheng, Yun-Qiu Wang, Cun-Fu Wang, Meng-Qi Jia, Huan-Min Niu, Qi-Qi Lu, Ya-Nan Wang, Dan Feng, Xiao-Xue Zheng, Hui-Qing Yuan. AGR2-induced cholesterol synthesis drives lovastatin resistance that is overcome by combination therapy with allicin. Acta pharmacologica Sinica. 2022 Nov; 43(11):2905-2916. doi: 10.1038/s41401-022-00909-3. [PMID: 35459869]
  • Weiyu Liu, Shaojun Xu, Shuangqin Liang, Changling Duan, Zhilan Xu, Le Zhao, Feifei Wen, Qiuyan Li, Yikui Li, Jinyan Zhang. Hypertensive vascular and cardiac remodeling protection by allicin in spontaneous hypertension rats via CaMK Ⅱ/NF-κB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Nov; 155(?):113802. doi: 10.1016/j.biopha.2022.113802. [PMID: 36271577]
  • Fabian Piskol, Kerstin Neubauer, Maurice Eggers, Lisa Margarete Bode, Jan Jasper, Alan Slusarenko, Edward Reijerse, Wolfgang Lubitz, Dieter Jahn, Jürgen Moser. Two-component carnitine monooxygenase from Escherichia coli: functional characterization, inhibition and mutagenesis of the molecular interface. Bioscience reports. 2022 09; 42(9):. doi: 10.1042/bsr20221102. [PMID: 36066069]
  • Jing-Ru Wang, Yong-Mei Hu, Han Zhou, An-Ping Li, Shao-Yong Zhang, Xiong-Fei Luo, Bao-Qi Zhang, Jun-Xia An, Zhi-Jun Zhang, Ying-Qian Liu. Allicin-Inspired Heterocyclic Disulfides as Novel Antimicrobial Agents. Journal of agricultural and food chemistry. 2022 Sep; 70(37):11782-11791. doi: 10.1021/acs.jafc.2c03765. [PMID: 36067412]
  • Suhad Sami Humadi, Samir Mohamed Awad, Ahmed Abd Elkader El-Rashedy, Mohamed Fathy El-Shehry. Design, synthesis, ADME, biological evaluation and molecular dynamic studies of natural and synthetic remedy of Herpes simplex virus type-1. Pakistan journal of pharmaceutical sciences. 2022 Jul; 35(4(Special)):1181-1190. doi: . [PMID: 36218096]
  • Xiaoming Wang, Yue Wang, Ci Fang, Qianmei Gong, Jinhu Huang, Yujuan Zhang, Liping Wang. Allicin affects the pharmacokinetics of sulfadiazine and florfenicol by downregulating the expression of jejunum P-gp and BCRP in broilers. Poultry science. 2022 Jul; 101(7):101947. doi: 10.1016/j.psj.2022.101947. [PMID: 35688033]
  • Maolin Li, Jinzhuo Ning, Houbao Huang, Shuchuan Jiang, Dong Zhuo. Allicin protects against renal ischemia-reperfusion injury by attenuating oxidative stress and apoptosis. International urology and nephrology. 2022 Jul; 54(7):1761-1768. doi: 10.1007/s11255-021-03014-2. [PMID: 34825305]
  • Paola Tedeschi, Manuela Nigro, Alessia Travagli, Martina Catani, Alberto Cavazzini, Stefania Merighi, Stefania Gessi. Therapeutic Potential of Allicin and Aged Garlic Extract in Alzheimer's Disease. International journal of molecular sciences. 2022 Jun; 23(13):. doi: 10.3390/ijms23136950. [PMID: 35805955]
  • Christina Schier, Jana Foerster Née Reiter, Monika Heupel, Philipp Dörner, Michael Klaas, Wolfgang Schröder, Lothar Rink, Alan J Slusarenko, Martin C H Gruhlke. Allicin as a Volatile or Nebulisable Antimycotic for the Treatment of Pulmonary Mycoses: In Vitro Studies Using a Lung Flow Test Rig. International journal of molecular sciences. 2022 Jun; 23(12):. doi: 10.3390/ijms23126607. [PMID: 35743050]
  • Qiqi Li, Yaping Zhang, Wangchang Li, Ke Yan, Yaru Liu, Huiyan Xu, Yangqing Lu, Xingwei Liang, Xiaogan Yang. Allicin protects porcine oocytes against LPS-induced defects during maturation in vitro. Theriogenology. 2022 Apr; 182(?):138-147. doi: 10.1016/j.theriogenology.2022.02.007. [PMID: 35176679]
  • Zhenglin Chang, Lingyue An, Zhican He, Yuyan Zhang, Shujue Li, Min Lei, Peng Xu, Yongchang Lai, Zheng Jiang, Yapeng Huang, Xiaolu Duan, Wenqi Wu. Allicin suppressed Escherichia coli-induced urinary tract infections by a novel MALT1/NF-κB pathway. Food & function. 2022 Mar; 13(6):3495-3511. doi: 10.1039/d1fo03853b. [PMID: 35246671]
  • Elena Catanzaro, Donatella Canistro, Valentina Pellicioni, Fabio Vivarelli, Carmela Fimognari. Anticancer potential of allicin: A review. Pharmacological research. 2022 03; 177(?):106118. doi: 10.1016/j.phrs.2022.106118. [PMID: 35134476]
  • Babatunde Joseph Oso, Akinwunmi Oluwaseun Adeoye, Ige Francis Olaoye. Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases. Journal of biomolecular structure & dynamics. 2022 Jan; 40(1):389-400. doi: 10.1080/07391102.2020.1813630. [PMID: 32876538]
  • Wenpeng Xie, Wenjie Chang, Xiaole Wang, Fei Liu, Xu Wang, Daotong Yuan, Yongkui Zhang. Allicin Inhibits Osteosarcoma Growth by Promoting Oxidative Stress and Autophagy via the Inactivation of the lncRNA MALAT1-miR-376a-Wnt/β-Catenin Signaling Pathway. Oxidative medicine and cellular longevity. 2022; 2022(?):4857814. doi: 10.1155/2022/4857814. [PMID: 35783190]
  • Yingying Zhang, Yinan Jiang, Ziying Wang, Jiayu Wang, Mingzhen Zhu, Hui Yang. Effects of Dietary Resveratrol, Bile Acids, Allicin, Betaine, and Inositol on Recovering the Lipid Metabolism Disorder in the Liver of Rare Minnow Gobiocypris rarus Caused by Bisphenol A. Aquaculture nutrition. 2022; 2022(?):6082343. doi: 10.1155/2022/6082343. [PMID: 36860429]
  • S Shamshad, K A Rizvi, H Shehnaz, S A Jatoi, L Shahnaz, S M S Naqvi, M Qasim, T Zainab, A Haider. Novel NARC-G1 garlic: comparative allicin quantification with morpho-biochemical & genetic profiling. Brazilian journal of biology = Revista brasleira de biologia. 2022; 84(?):e262697. doi: 10.1590/1519-6984.262697. [PMID: 35976350]
  • Batool Mahdi, Rana Abu-Huwaij, Iqbal Al-Khateeb. Development of topical patches releasing allicin using garlic extract. Journal of cosmetic dermatology. 2022 Jan; 21(1):396-402. doi: 10.1111/jocd.14553. [PMID: 34713965]
  • Hanan A Edres, Nabil M Taha, Mohamed A Lebda, Mohamed S Elfeky. The potential neuroprotective effect of allicin and melatonin in acrylamide-induced brain damage in rats. Environmental science and pollution research international. 2021 Nov; 28(41):58768-58780. doi: 10.1007/s11356-021-14800-x. [PMID: 34120280]
  • Lorena Avila-Carrasco, Elda Araceli García-Mayorga, Daisy L Díaz-Avila, Idalia Garza-Veloz, Margarita L Martinez-Fierro, Guadalupe T González-Mateo. Potential Therapeutic Effects of Natural Plant Compounds in Kidney Disease. Molecules (Basel, Switzerland). 2021 Oct; 26(20):. doi: 10.3390/molecules26206096. [PMID: 34684678]
  • Yungang Shan, Deqing Chen, Bo Hu, Guangtao Xu, Wanlu Li, Ye Jin, Xiuhui Jin, Xin Jin, Limin Jin. Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Oct; 142(?):112077. doi: 10.1016/j.biopha.2021.112077. [PMID: 34426252]
  • Peirong Cai, Qihang Zhu, Qianying Cao, Yuni Bai, Hui Zou, Jianhong Gu, Yan Yuan, Xuezhong Liu, Zongping Liu, Jianchun Bian. Quercetin and Allicin Can Alleviate the Hepatotoxicity of Lead (Pb) through the PI3K Signaling Pathway. Journal of agricultural and food chemistry. 2021 Aug; 69(32):9451-9460. doi: 10.1021/acs.jafc.1c03794. [PMID: 34372660]
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