Albanol A (BioDeep_00000006947)

 

Secondary id: BioDeep_00000396553, BioDeep_00001869591

PANOMIX_OTCML-2023


代谢物信息卡片


Mulberrofuran G

化学式: C34H26O8 (562.1627596000001)
中文名称: 桑呋喃 G, 桑呋喃 G
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12c(ccc(c1)O)cc(o2)c1cc(c2c(c1)O[C@@]1([C@H]3[C@H]2C=C(C[C@@H]3c2c(O1)cc(cc2)O)C)c1c(cc(cc1)O)O)O
InChI: InChI=1S/C34H26O8/c1-16-8-23-22-6-4-21(37)15-30(22)41-34(25-7-5-19(35)13-26(25)38)33(23)24(9-16)32-27(39)10-18(12-31(32)42-34)28-11-17-2-3-20(36)14-29(17)40-28/h2-7,9-15,23-24,33,35-39H,8H2,1H3/t23-,24+,33-,34-/m1/s1

描述信息

Mulberrofuran G protects ischemic injury-induced cell death via inhibition of NOX4-mediated ROS generation and ER stress[1]. Mulberrofuran G shows moderate inhibiting activity of hepatitis B virus (HBV) DNA replication with IC50 of 3.99 μM[2].
Mulberrofuran G protects ischemic injury-induced cell death via inhibition of NOX4-mediated ROS generation and ER stress[1]. Mulberrofuran G shows moderate inhibiting activity of hepatitis B virus (HBV) DNA replication with IC50 of 3.99 μM[2].
Mulberrofuran G protects ischemic injury-induced cell death via inhibition of NOX4-mediated ROS generation and ER stress[1]. Mulberrofuran G shows moderate inhibiting activity of hepatitis B virus (HBV) DNA replication with IC50 of 3.99 μM[2].

同义名列表

2 个代谢物同义名

Mulberrofuran G; Albanol A



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Fatma M Abdel Bar, Ghada M Abbas, Ahmed A Gohar, Mohamed-Farid I Lahloub. Antiproliferative activity of stilbene derivatives and other constituents from the stem bark of Morus nigra L. Natural product research. 2020 Dec; 34(24):3506-3513. doi: 10.1080/14786419.2019.1573236. [PMID: 30822142]
  • Pradeep Paudel, Se Eun Park, Su Hui Seong, Hyun Ah Jung, Jae Sue Choi. Novel Diels-Alder Type Adducts from Morus alba Root Bark Targeting Human Monoamine Oxidase and Dopaminergic Receptors for the Management of Neurodegenerative Diseases. International journal of molecular sciences. 2019 Dec; 20(24):. doi: 10.3390/ijms20246232. [PMID: 31835621]
  • Pradeep Paudel, Ting Yu, Su Hui Seong, Eun Bi Kuk, Hyun Ah Jung, Jae Sue Choi. Protein Tyrosine Phosphatase 1B Inhibition and Glucose Uptake Potentials of Mulberrofuran G, Albanol B, and Kuwanon G from Root Bark of Morus alba L. in Insulin-Resistant HepG2 Cells: An In Vitro and In Silico Study. International journal of molecular sciences. 2018 May; 19(5):. doi: 10.3390/ijms19051542. [PMID: 29786669]
  • Ming Li, Xuewei Wu, Xiaoning Wang, Tao Shen, Dongmei Ren. Two novel compounds from the root bark of Morus alba L. Natural product research. 2018 Jan; 32(1):36-42. doi: 10.1080/14786419.2017.1327862. [PMID: 28521570]
  • Ghada M Abbas, Fatma M Abdel Bar, Hany N Baraka, Ahmed A Gohar, Mohammed-Farid Lahloub. A new antioxidant stilbene and other constituents from the stem bark of Morus nigra L. Natural product research. 2014; 28(13):952-9. doi: 10.1080/14786419.2014.900770. [PMID: 24673367]
  • Chang-An Geng, Yun-Bao Ma, Xue-Mei Zhang, Shu-Ying Yao, Duo-Qing Xue, Rong-Ping Zhang, Ji-Jun Chen. Mulberrofuran G and isomulberrofuran G from Morus alba L.: anti-hepatitis B virus activity and mass spectrometric fragmentation. Journal of agricultural and food chemistry. 2012 Aug; 60(33):8197-202. doi: 10.1021/jf302639b. [PMID: 22835135]
  • Takashi Kikuchi, Masatoshi Nihei, Hisashi Nagai, Hidekuni Fukushi, Keiichi Tabata, Takashi Suzuki, Toshihiro Akihisa. Albanol A from the root bark of Morus alba L. induces apoptotic cell death in HL60 human leukemia cell line. Chemical & pharmaceutical bulletin. 2010 Apr; 58(4):568-71. doi: 10.1248/cpb.58.568. [PMID: 20410645]
  • Qing-Jian Zhang, Yan-Bo Tang, Ruo-Yun Chen, De-Quan Yu. Three new cytotoxic Diels-Alder-type adducts from Morus australis. Chemistry & biodiversity. 2007 Jul; 4(7):1533-40. doi: 10.1002/cbdv.200790133. [PMID: 17638335]