Isomangiferin (BioDeep_00000000057)
Secondary id: BioDeep_00000311964
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
1,3,6,7-Tetrahydroxy-4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-9H-xanthen-9-one
化学式: C19H18O11 (422.0849078)
中文名称: 异杞果素, 异芒果苷, 异芒果苷
谱图信息:
最多检出来源 Viridiplantae(otcml) 33.72%
分子结构信息
SMILES: C1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
InChI: InChI=1S/C19H18O11/c20-4-11-15(26)16(27)17(28)19(30-11)13-9(24)2-8(23)12-14(25)5-1-6(21)7(22)3-10(5)29-18(12)13/h1-3,11,15-17,19-24,26-28H,4H2
描述信息
Isomangiferin is a member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7 and a 1,5-anhydro-D-glucitol moiety at position 1. It has a role as an anti-HSV-1 agent and a plant metabolite. It is a member of xanthones, a C-glycosyl compound and a polyphenol.
Isomangiferin is a natural product found in Cystopteris moupinensis, Cystopteris montana, and other organisms with data available.
Isomangiferin is found in fruits. Isomangiferin is a constituent of Mangifera indica (mango)
Constituent of Mangifera indica (mango). Isomangiferin is found in fruits.
Isomangiferin, a natural product, is reported to have antiviral activity.
Isomangiferin, a natural product, is reported to have antiviral activity.
同义名列表
12 个代谢物同义名
1,3,6,7-Tetrahydroxy-4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-9H-xanthen-9-one; 1,3,6,7-tetrahydroxy-4-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one; 1,3,6,7-tetrahydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-9H-xanthen-9-one; 1,3,6,7-tetrahydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one; (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-4-yl)-D-glucitol; 9H-Xanthen-9-one, 4-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy-; 4-b-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one, 9ci; 9H-Xanthen-9-one, 4-ss-D-glucopyranosyl-1,3,6,7-tetrahydroxy-; 4-beta-d-glucopyranosyl-1,3,6,7-tetrahydroxy-9h-xanthen-9-one; 4-C-Glucosyl-1,3,6,7-tetrahydroxyxanthone; 4-Glucosyl-1,3,6,7-tetrahydroxyxanthone; Isomangiferin
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:80840
- KEGG: C16979
- PubChem: 15559961
- PubChem: 5318597
- HMDB: HMDB0029477
- Metlin: METLIN71478
- MeSH: isomangiferin
- ChemIDplus: 0024699169
- KNApSAcK: C00041015
- foodb: FDB000601
- chemspider: 11255006
- chemspider: 4477132
- CAS: 24699-16-9
- medchemexpress: HY-N0772
- PMhub: MS000025526
- PubChem: 96023465
- NIKKAJI: J17.231F
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
171 个相关的物种来源信息
- 33090 知母: -
- 673928 Hypericum hirsutum:
- 1210469 Eleutherine bulbosa: 10.1515/ZNC-1985-5-608
- 354415 Rigidella: 10.1515/ZNC-1985-5-608
- 501383 Tigridia orthantha: 10.1515/ZNC-1985-5-608
- 384038 Cyclopia intermedia: 10.1021/JF980258X
- 269006 Hypericum maculatum:
- 34205 Iris germanica:
- 1321321 Hypericum aucheri:
- 282556 Hypericum sikokumontanum: 10.1016/J.PHYTOCHEM.2008.11.006
- 1641286 Hedysarum inundatum: 10.1007/BF00630415
- 57576 Hedysarum alpinum:
- 29780 Mangifera indica:
- 198761 Cratoxylum formosum: 10.1016/S0031-9422(98)00467-1
- 673929 Hypericum montanum: 10.1016/S0305-1978(98)00010-6
- 55963 Hypericum calycinum: 10.1016/S0305-1978(98)00010-6
- 1321328 Hypericum elegans: 10.1016/S0305-1978(98)00010-6
- 212239 Hypericum patulum: 10.1016/S0305-1978(98)00010-6
- 140968 Hypericum androsaemum: 10.1016/S0305-1978(98)00010-6
- 282558 Hypericum triquetrifolium: 10.1016/S0305-1978(98)00010-6
- 210378 Hypericum ascyron: 10.1016/S0305-1978(98)00010-6
- 1321348 Hypericum rochelii: 10.1016/S0305-1978(98)00010-6
- 268982 Hypericum cerastioides: 10.1016/S0305-1978(98)00010-6
- 626745 Hypericum bupleuroides: 10.1016/S0305-1978(98)00010-6
- 1136959 Hypericum bithynicum: 10.1016/S0305-1978(98)00010-6
- 1136992 Hypericum linarioides: 10.1016/S0305-1978(98)00010-6
- 673934 Hypericum richeri: 10.1016/S0305-1978(98)00010-6
- 282549 Hypericum olympicum: 10.1016/S0305-1978(98)00010-6
- 282533 Hypericum attenuatum: 10.1016/S0305-1978(98)00010-6
- 65561 Hypericum perforatum: 10.1016/S0305-1978(98)00010-6
- 626749 Hypericum tetrapterum: 10.1016/S0305-1978(98)00010-6
- 1137008 Hypericum perfoliatum: 10.1016/S0305-1978(98)00010-6
- 1137004 Hypericum origanifolium: 10.1016/S0305-1978(98)00010-6
- 673931 Hypericum polyphyllum: 10.1016/S0305-1978(98)00010-6
- 1321357 Hypericum thasium: 10.1016/S0305-1978(98)00010-6
- 282542 Hypericum japonicum: 10.1016/S0305-1978(98)00010-6
- 673922 Hypericum barbatum: 10.1016/S0305-1978(98)00010-6
- 1137022 Hypericum scabrum: 10.1016/S0305-1978(98)00010-6
- 1137017 Hypericum rumeliacum: 10.1016/S0305-1978(98)00010-6
- 257780 Hypericum empetrifolium: 10.1016/S0305-1978(98)00010-6
- 1136997 Hypericum montbretii: 10.1016/S0305-1978(98)00010-6
- 708052 Hypericum annulatum: 10.1016/S0305-1978(98)00010-6
- 32117 Gymnocarpium oyamense: 10.1021/NP50029A025
- 86705 Acystopteris japonica: 10.1021/NP50029A025
- 1498956 Woodsia scopulina: 10.1021/NP50029A025
- 623704 Gymnocarpium remotepinnatum: 10.1021/NP50029A025
- 1701597 Woodsia montevidensis: 10.1021/NP50029A025
- 32116 Gymnocarpium dryopteris: 10.1021/NP50029A025
- 1328778 Cystopteris diaphana: 10.1021/NP50029A025
- 208747 Deparia henryi: 10.1021/NP50029A025
- 1328779 Cystopteris douglasii: 10.1021/NP50029A025
- 2706154 Physematium manchuriense: 10.1021/NP50029A025
- 2706189 Physematium molle: 10.1021/NP50029A025
- 86685 Athyrium atkinsonii: 10.1021/NP50029A025
- 1303118 Woodsia alpina: 10.1021/NP50029A025
- 65727 Deparia petersenii: 10.1021/NP50029A025
- 2706187 Physematium elongatum: 10.1021/NP50029A025
- 1111059 Cystopteris moupinensis: 10.1021/NP50029A025
- 1891472 Cystopteris fragilis var. fragilis: 10.1021/NP50029A025
- 1701598 Woodsia rosthorniana: 10.1021/NP50029A025
- 208745 Deparia boryana: 10.1021/NP50029A025
- 208735 Deparia japonica: 10.1021/NP50029A025
- 32112 Cystopteris fragilis:
- 1328776 Cystopteris alpina: 10.1021/NP50029A025
- 872508 Cystopteris sudetica: 10.1021/NP50029A025
- 872911 Woodsia ilvensis: 10.1021/NP50029A025
- 983334 Gymnocarpium robertianum: 10.1021/NP50029A025
- 1133549 Cystopteris montana: 10.1021/NP50029A025
- 32120 Woodsia polystichoides: 10.1021/NP50029A025
- 872333 Acystopteris tenuisecta: 10.1021/NP50029A025
- 872910 Woodsia glabella: 10.1021/NP50029A025
- 29611 Woodsia obtusa: 10.1021/NP50029A025
- 18795 Delairea odorata: 10.1016/0031-9422(96)00154-9
- 2710877 Hedysarum flavescens: 10.1007/BF00564793
- 59045 Anemarrhena asphodeloides:
- 58944 Iris domestica:
- 282553 Hypericum sampsonii: 10.3987/R-1985-10-2543
- 34213 Iris ensata: 10.1007/BF00563849
- 1960946 Hedysarum denticulatum: 10.1007/BF00563966
- 243998 Asplenium montanum: 10.1016/S0031-9422(00)97205-4
- 58944 Iris domestica:
- 282556 Hypericum sikokumontanum: 10.3987/R-1985-10-2543
- 155109 Cyclopia subternata:
- 673928 Hypericum hirsutum:
- 1210469 Eleutherine bulbosa: 10.1515/ZNC-1985-5-608
- 354415 Rigidella: 10.1515/ZNC-1985-5-608
- 501383 Tigridia orthantha: 10.1515/ZNC-1985-5-608
- 384038 Cyclopia intermedia: 10.1021/JF980258X
- 269006 Hypericum maculatum:
- 34205 Iris germanica:
- 1321321 Hypericum aucheri:
- 282556 Hypericum sikokumontanum: 10.1016/J.PHYTOCHEM.2008.11.006
- 1641286 Hedysarum inundatum: 10.1007/BF00630415
- 57576 Hedysarum alpinum:
- 29780 Mangifera indica:
- 198761 Cratoxylum formosum: 10.1016/S0031-9422(98)00467-1
- 673929 Hypericum montanum: 10.1016/S0305-1978(98)00010-6
- 55963 Hypericum calycinum: 10.1016/S0305-1978(98)00010-6
- 1321328 Hypericum elegans: 10.1016/S0305-1978(98)00010-6
- 212239 Hypericum patulum: 10.1016/S0305-1978(98)00010-6
- 140968 Hypericum androsaemum: 10.1016/S0305-1978(98)00010-6
- 282558 Hypericum triquetrifolium: 10.1016/S0305-1978(98)00010-6
- 210378 Hypericum ascyron: 10.1016/S0305-1978(98)00010-6
- 1321348 Hypericum rochelii: 10.1016/S0305-1978(98)00010-6
- 268982 Hypericum cerastioides: 10.1016/S0305-1978(98)00010-6
- 626745 Hypericum bupleuroides: 10.1016/S0305-1978(98)00010-6
- 1136959 Hypericum bithynicum: 10.1016/S0305-1978(98)00010-6
- 1136992 Hypericum linarioides: 10.1016/S0305-1978(98)00010-6
- 673934 Hypericum richeri: 10.1016/S0305-1978(98)00010-6
- 282549 Hypericum olympicum: 10.1016/S0305-1978(98)00010-6
- 282533 Hypericum attenuatum: 10.1016/S0305-1978(98)00010-6
- 65561 Hypericum perforatum: 10.1016/S0305-1978(98)00010-6
- 626749 Hypericum tetrapterum: 10.1016/S0305-1978(98)00010-6
- 1137008 Hypericum perfoliatum: 10.1016/S0305-1978(98)00010-6
- 1137004 Hypericum origanifolium: 10.1016/S0305-1978(98)00010-6
- 673931 Hypericum polyphyllum: 10.1016/S0305-1978(98)00010-6
- 1321357 Hypericum thasium: 10.1016/S0305-1978(98)00010-6
- 282542 Hypericum japonicum: 10.1016/S0305-1978(98)00010-6
- 673922 Hypericum barbatum: 10.1016/S0305-1978(98)00010-6
- 1137022 Hypericum scabrum: 10.1016/S0305-1978(98)00010-6
- 1137017 Hypericum rumeliacum: 10.1016/S0305-1978(98)00010-6
- 257780 Hypericum empetrifolium: 10.1016/S0305-1978(98)00010-6
- 1136997 Hypericum montbretii: 10.1016/S0305-1978(98)00010-6
- 708052 Hypericum annulatum: 10.1016/S0305-1978(98)00010-6
- 32117 Gymnocarpium oyamense: 10.1021/NP50029A025
- 86705 Acystopteris japonica: 10.1021/NP50029A025
- 1498956 Woodsia scopulina: 10.1021/NP50029A025
- 623704 Gymnocarpium remotepinnatum: 10.1021/NP50029A025
- 1701597 Woodsia montevidensis: 10.1021/NP50029A025
- 32116 Gymnocarpium dryopteris: 10.1021/NP50029A025
- 1328778 Cystopteris diaphana: 10.1021/NP50029A025
- 208747 Deparia henryi: 10.1021/NP50029A025
- 1328779 Cystopteris douglasii: 10.1021/NP50029A025
- 2706154 Physematium manchuriense: 10.1021/NP50029A025
- 2706189 Physematium molle: 10.1021/NP50029A025
- 86685 Athyrium atkinsonii: 10.1021/NP50029A025
- 1303118 Woodsia alpina: 10.1021/NP50029A025
- 65727 Deparia petersenii: 10.1021/NP50029A025
- 2706187 Physematium elongatum: 10.1021/NP50029A025
- 1111059 Cystopteris moupinensis: 10.1021/NP50029A025
- 1891472 Cystopteris fragilis var. fragilis: 10.1021/NP50029A025
- 1701598 Woodsia rosthorniana: 10.1021/NP50029A025
- 208745 Deparia boryana: 10.1021/NP50029A025
- 208735 Deparia japonica: 10.1021/NP50029A025
- 32112 Cystopteris fragilis:
- 1328776 Cystopteris alpina: 10.1021/NP50029A025
- 872508 Cystopteris sudetica: 10.1021/NP50029A025
- 872911 Woodsia ilvensis: 10.1021/NP50029A025
- 983334 Gymnocarpium robertianum: 10.1021/NP50029A025
- 1133549 Cystopteris montana: 10.1021/NP50029A025
- 32120 Woodsia polystichoides: 10.1021/NP50029A025
- 872333 Acystopteris tenuisecta: 10.1021/NP50029A025
- 872910 Woodsia glabella: 10.1021/NP50029A025
- 29611 Woodsia obtusa: 10.1021/NP50029A025
- 18795 Delairea odorata: 10.1016/0031-9422(96)00154-9
- 2710877 Hedysarum flavescens: 10.1007/BF00564793
- 59045 Anemarrhena asphodeloides:
- 58944 Iris domestica:
- 282553 Hypericum sampsonii: 10.3987/R-1985-10-2543
- 34213 Iris ensata: 10.1007/BF00563849
- 1960946 Hedysarum denticulatum: 10.1007/BF00563966
- 243998 Asplenium montanum: 10.1016/S0031-9422(00)97205-4
- 58944 Iris domestica:
- 282556 Hypericum sikokumontanum: 10.3987/R-1985-10-2543
- 155109 Cyclopia subternata:
- 9606 Homo sapiens: -
- 746523 Pyrrosia sheareri (Bak. ) Ching: -
- 187374 Pyrrosia lingua (Thunb.) Farwell: -
- 746522 Pyrrosia petiolosa (Christ) Ching: -
- 59045 Anemarrhena asphodeloides Bge.: -
- 33090 Plants: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Neil Miller, Christiaan J Malherbe, Elizabeth Joubert. In vitroα-glucosidase inhibition by honeybush (Cyclopia genistoides) food ingredient extract-potential for dose reduction of acarbose through synergism.
Food & function.
2020 Jul; 11(7):6476-6486. doi:
10.1039/d0fo01306d. [PMID: 32627774] - Wei Xiao, Yude Peng, Zhexu Tan, Qiuyue Lv, Chi-On Chan, Jingyu Yang, Sibao Chen. Comparative Evaluation of Chemical Profiles of Pyrrosiae Folium Originating from Three Pyrrosia Species by HPLC-DAD Combined with Multivariate Statistical Analysis.
Molecules (Basel, Switzerland).
2017 Dec; 22(12):. doi:
10.3390/molecules22122122. [PMID: 29194397] - Fengjun Sun, Zhirui Liu, Bo Yang, Peiyuan Xia. Development and validation of a liquid chromatography with tandem mass spectrometry method for the determination of isomangiferin in rat plasma with application to a preclinical pharmacokinetic study.
Journal of separation science.
2016 Aug; 39(15):2890-5. doi:
10.1002/jssc.201501408. [PMID: 27257129] - Guo-long Li, Jie Yang, Jin-ao Duan, Hong-bo Liu, Zhen-hua Zhu, Da-wei Qian, Zhi-shu Tang. [Quality Analysis and Evaluation of Anemarrhena asphodeloides Rhizome from Different Habitats].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2015 Jun; 38(6):1148-52. doi:
. [PMID: 26762052] - Nireshni Chellan, Elizabeth Joubert, Hans Strijdom, Candice Roux, Johan Louw, Christo J F Muller. Aqueous extract of unfermented honeybush (Cyclopia maculata) attenuates STZ-induced diabetes and β-cell cytotoxicity.
Planta medica.
2014 Jun; 80(8-9):622-9. doi:
10.1055/s-0034-1368457. [PMID: 24853761] - Christiaan J Malherbe, Elize Willenburg, Dalene de Beer, Susan L Bonnet, Jan H van der Westhuizen, Elizabeth Joubert. Iriflophenone-3-C-glucoside from Cyclopia genistoides: isolation and quantitative comparison of antioxidant capacity with mangiferin and isomangiferin using on-line HPLC antioxidant assays.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Mar; 951-952(?):164-71. doi:
10.1016/j.jchromb.2014.01.038. [PMID: 24566268] - Adam Kokotkiewicz, Malgorzata Wnuk, Adam Bucinski, Maria Luczkiewicz. In vitro cultures of Cyclopia plants (honeybush) as a source of bioactive xanthones and flavanones.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2009 Jul; 64(7-8):533-40. doi:
10.1515/znc-2009-7-812. [PMID: 19791506] - Dalene de Beer, Gerold Jerz, Elizabeth Joubert, Victor Wray, Peter Winterhalter. Isolation of isomangiferin from honeybush (Cyclopia subternata) using high-speed counter-current chromatography and high-performance liquid chromatography.
Journal of chromatography. A.
2009 May; 1216(19):4282-9. doi:
10.1016/j.chroma.2009.02.056. [PMID: 19272608] - Yanguo Sun, Xi Zhang, Xingya Xue, Yan Zhang, Hongbin Xiao, Xinmiao Liang. Rapid identification of polyphenol C-glycosides from Swertia franchetiana by HPLC-ESI-MS-MS.
Journal of chromatographic science.
2009 Mar; 47(3):190-6. doi:
10.1093/chromsci/47.3.190. [PMID: 19298704] - Jianchen Li, Li Feng, Jing Dai, Runbiao Wang, Toshihiro Nohara. [Chemical constituents from Polygala telephioides].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2009 Feb; 34(4):402-5. doi:
. [PMID: 19459299] - M Nurul Islam, Hye Hyun Yoo, Jun Lee, Joo Won Nam, Eun Kyoung Seo, Changbae Jin, Dong-Hyun Kim. Simultaneous determination of bioactive xanthone glycosides and norlignans from ethanolic extract of Anemarrhena asphodeloides by liquid chromatography.
Journal of AOAC International.
2008 Nov; 91(6):1271-7. doi:
. [PMID: 19202786] - Frédéric Martin, Anne-Emmanuelle Hay, Delphine Cressend, Marianne Reist, Livia Vivas, Mahabir P Gupta, Pierre-Alain Carrupt, Kurt Hostettmann. Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera.
Journal of natural products.
2008 Nov; 71(11):1887-90. doi:
10.1021/np800406q. [PMID: 18950229] - J Li, Y Y Tong. [Determination of active constituents in shi-wei (Folium Pyrrosiae) by high performance liquid chromatography].
Yao xue xue bao = Acta pharmaceutica Sinica.
1992; 27(2):153-6. doi:
. [PMID: 1414373]