Ajugasterone C (BioDeep_00000000562)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(2S,3R,5R,9R,10R,11R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methyl-heptan-2-yl]-2,3,11,14-tetrahydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one

化学式: C27H44O7 (480.3087)
中文名称: 筋骨草甾酮C, 筋骨草甾酮 C
谱图信息: 最多检出来源 not specific(not specific) 0%

分子结构信息

SMILES: CC(C)CCC(C(C)(C1CCC2(C1(CC(C3C2=CC(=O)C4C3(CC(C(C4)O)O)C)O)C)O)O)O
InChI: InChI=1S/C27H44O7/c1-14(2)6-7-22(32)26(5,33)21-8-9-27(34)16-11-17(28)15-10-18(29)19(30)12-24(15,3)23(16)20(31)13-25(21,27)4/h11,14-15,18-23,29-34H,6-10,12-13H2,1-5H3/t15-,18+,19-,20+,21-,22+,23+,24-,25+,26+,27+/m0/s1

描述信息

Ajugasterone C is a steroid.
Ajugasterone C is a natural product found in Zoanthus, Cyanotis arachnoidea, and other organisms with data available.
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones

同义名列表

10 个代谢物同义名

Cholest-7-en-6-one, 2,3,11,14,20,22-hexahydroxy-, (2beta,3beta,5beta,11alpha,22R)-; 2,3,11,14,20,22-Hexahydroxycholest-7-en-6-one; Ajugasterone C; (2S,3R,5R,9R,10R,11R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methyl-heptan-2-yl]-2,3,11,14-tetrahydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; (2S,3R,5R,9R,10R,11R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,11,14-tetrahydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; (2S,3R,5R,9R,10R,11R,13R,14S,17S)-17-[(1R,2R)-1,2-dihydroxy-1,5-dimethyl-hexyl]-2,3,11,14-tetrahydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; (2S,3R,5R,9R,10R,11R,13R,14S,17S)-17-[(1R,2R)-1,2-dihydroxy-1,5-dimethylhexyl]-2,3,11,14-tetrahydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; 23044-80-6; C08811; Ajugasterone C



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

77 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 BCL2, CASP3, DCTN4, MAPK3, MTOR, PIK3CA, RB1
Peripheral membrane protein 1 MTOR
Endoplasmic reticulum membrane 2 BCL2, MTOR
Nucleus 7 BCL2, CASP3, DCTN4, MAPK3, MTOR, PARP1, RB1
autophagosome 1 MAP1LC3A
cytosol 9 BCL2, CASP3, DCTN4, MAP1LC3A, MAPK3, MTOR, PARP1, PIK3CA, RB1
dendrite 1 MTOR
nuclear body 1 PARP1
phagocytic vesicle 1 MTOR
centrosome 1 DCTN4
nucleoplasm 5 CASP3, MAPK3, MTOR, PARP1, RB1
Cell membrane 1 TNF
Lipid-anchor 1 MAP1LC3A
Cytoplasmic side 1 MTOR
lamellipodium 1 PIK3CA
Golgi apparatus membrane 1 MTOR
cell cortex 1 DCTN4
cell surface 1 TNF
glutamatergic synapse 3 CASP3, MAP1LC3A, MAPK3
Golgi apparatus 1 MAPK3
Golgi membrane 2 INS, MTOR
lysosomal membrane 1 MTOR
neuronal cell body 2 CASP3, TNF
Cytoplasm, cytosol 1 PARP1
Lysosome 1 MTOR
plasma membrane 4 IFNLR1, MAPK3, PIK3CA, TNF
Membrane 4 BCL2, IFNLR1, MTOR, PARP1
caveola 1 MAPK3
Lysosome membrane 1 MTOR
endoplasmic reticulum 1 BCL2
extracellular space 2 INS, TNF
perinuclear region of cytoplasm 1 PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 3 BCL2, MAPK3, PARP1
protein-containing complex 2 BCL2, PARP1
intracellular membrane-bounded organelle 1 MAP1LC3A
Microsome membrane 1 MTOR
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 IFNLR1
Secreted 1 INS
extracellular region 2 INS, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, MTOR
transcription regulator complex 1 PARP1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 DCTN4
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
nucleolus 1 PARP1
Early endosome 1 MAPK3
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
Cell junction, focal adhesion 1 MAPK3
Cytoplasm, cytoskeleton 2 DCTN4, MAP1LC3A
focal adhesion 2 DCTN4, MAPK3
microtubule 1 MAP1LC3A
spindle 1 RB1
Nucleus, PML body 1 MTOR
PML body 2 MTOR, RB1
Cytoplasm, myofibril, sarcomere 1 DCTN4
Late endosome 2 MAP1LC3A, MAPK3
sarcomere 1 DCTN4
chromatin 2 PARP1, RB1
Cytoplasmic vesicle, autophagosome membrane 1 MAP1LC3A
autophagosome membrane 1 MAP1LC3A
phagocytic cup 1 TNF
Chromosome 1 PARP1
cytoskeleton 1 MAPK3
Nucleus, nucleolus 1 PARP1
spindle pole 1 DCTN4
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
Cytoplasm, cell cortex 1 DCTN4
organelle membrane 1 MAP1LC3A
site of double-strand break 1 PARP1
nuclear envelope 3 MAPK3, MTOR, PARP1
Endomembrane system 2 MAP1LC3A, MTOR
endosome lumen 1 INS
Membrane, caveola 1 MAPK3
myelin sheath 1 BCL2
pseudopodium 1 MAPK3
stress fiber 1 DCTN4
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, MAPK3
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
dynactin complex 1 DCTN4
kinetochore 1 DCTN4
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
SWI/SNF complex 1 RB1
cytoplasmic dynein complex 1 DCTN4
Cytoplasm, cytoskeleton, stress fiber 1 DCTN4
protein-DNA complex 1 PARP1
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, phagosome 1 MTOR
site of DNA damage 1 PARP1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome 1 MAP1LC3A
chromatin lock complex 1 RB1
Rb-E2F complex 1 RB1
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
BAD-BCL-2 complex 1 BCL2
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Jia-Jun Wu, Ka-Wing Cheng, Hao Wang, Wen-Cai Ye, Edmund T S Li, Mingfu Wang. Simultaneous determination of three phytoecdysteroids in the roots of four medicinal plants from the genus Asparagus by HPLC. Phytochemical analysis : PCA. 2009 Jan; 20(1):58-63. doi: 10.1002/pca.1097. [PMID: 19086092]
  • V N Odinokov, I V Galyautdinov, D V Nedopekin, L M Khalilov, A S Shashkov, V V Kachala, L Dinan, R Lafont. Phytoecdysteroids from the juice of Serratula coronata L. (Asteraceae). Insect biochemistry and molecular biology. 2002 Feb; 32(2):161-5. doi: 10.1016/s0965-1748(01)00106-0. [PMID: 11755058]