arcaine (BioDeep_00000005076)

   


代谢物信息卡片


arcaine

化学式: C6H16N6 (172.1436376)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(feces) 3.92%

分子结构信息

SMILES: C(CCN=C(N)N)CN=C(N)N
InChI: InChI=1S/C6H16N6/c7-5(8)11-3-1-2-4-12-6(9)10/h1-4H2,(H4,7,8,11)(H4,9,10,12)

描述信息

D007004 - Hypoglycemic Agents > D001645 - Biguanides

同义名列表

1 个代谢物同义名

arcaine



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tate N Winter, William F Elmquist, Carolyn A Fairbanks. OCT2 and MATE1 provide bidirectional agmatine transport. Molecular pharmaceutics. 2011 Feb; 8(1):133-42. doi: 10.1021/mp100180a. [PMID: 21128598]
  • Nádia Aléssio Velloso Bellé, Gerusa Duarte Dalmolin, Graciela Fonini, Maribel Antonello Rubin, João Batista Teixeira Rocha. Polyamines reduces lipid peroxidation induced by different pro-oxidant agents. Brain research. 2004 May; 1008(2):245-51. doi: 10.1016/j.brainres.2004.02.036. [PMID: 15145762]
  • Yoko Sakakibara, Hiroshi Yanagisawa. Agmatine deiminase from cucumber seedlings is a mono-specific enzyme: purification and characteristics. Protein expression and purification. 2003 Jul; 30(1):88-93. doi: 10.1016/s1046-5928(03)00071-8. [PMID: 12821325]
  • H Yanagisawa. Agmatine deiminase from maize shoots: purification and properties. Phytochemistry. 2001 Apr; 56(7):643-7. doi: 10.1016/s0031-9422(00)00491-x. [PMID: 11314948]
  • A Padiglia, R Medda, A Lorrai, B Murgia, J Z Pedersen, A F Agrò, G Floris. Interaction of pig kidney and lentil seedling copper-containing amine oxidases with guanidinium compounds. Journal of enzyme inhibition. 2000; 15(1):91-100. doi: . [PMID: 10850957]
  • L Daeffler, K Nadra, V Eichwald, S Ohresser, Y Landry. Effect of NMDA receptor ligands on mast cell histamine release, a reappraisal. Naunyn-Schmiedeberg's archives of pharmacology. 1999 Jun; 359(6):512-8. doi: 10.1007/pl00005384. [PMID: 10431764]
  • L M Zhou, X S He, G Li, B R de Costa, P Skolnick. Synthesis of N,N'-substituted piperazine and homopiperazine derivatives with polyamine-like actions at N-methyl-D-aspartate receptors. Journal of medicinal chemistry. 1995 Dec; 38(25):4891-6. doi: 10.1021/jm00025a006. [PMID: 8523402]
  • P Chandler, M Pennington, M L Maccecchini, N T Nashed, P Skolnick. Polyamine-like actions of peptides derived from conantokin-G, an N-methyl-D-aspartate (NMDA) antagonist. The Journal of biological chemistry. 1993 Aug; 268(23):17173-8. doi: 10.1016/s0021-9258(19)85318-8. [PMID: 8349604]
  • G Floris, A Rinaldi, A Finazzi-Agrò. Heat-denaturation of pig kidney diamine oxidase: effect of arcaine. The Italian journal of biochemistry. 1981 May; 30(3):251-8. doi: . [PMID: 6792107]