Acetaldehyde (BioDeep_00000004377)

 

Secondary id: BioDeep_00000405408

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


Acetic aldehyde

化学式: C2H4O (44.0262)
中文名称: 乙醛-13C2, 乙醛
谱图信息: 最多检出来源 Homo sapiens(blood) 32.04%

分子结构信息

SMILES: CC=O
InChI: InChI=1S/C2H4O/c1-2-3/h2H,1H3

描述信息

Acetaldehyde, also known as ethanal, belongs to the class of organic compounds known as short-chain aldehydes. These are an aldehyde with a chain length containing between 2 and 5 carbon atoms. Acetaldehyde exists in all living species, ranging from bacteria to humans. Within humans, acetaldehyde participates in a number of enzymatic reactions. In particular, acetaldehyde can be biosynthesized from ethanol which is mediated by the enzyme alcohol dehydrogenase 1B. Acetaldehyde can also be converted to acetic acid by the enzyme aldehyde dehydrogenase (mitochondrial) and aldehyde dehydrogenase X (mitochondrial). The main method of production is the oxidation of ethylene by the Wacker process, which involves oxidation of ethylene using a homogeneous palladium/copper system: 2 CH2CH2 + O2 → 2 CH3CHO. In the 1970s, the world capacity of the Wacker-Hoechst direct oxidation process exceeded 2 million tonnes annually. In humans, acetaldehyde is involved in disulfiram action pathway. Acetaldehyde is an aldehydic, ethereal, and fruity tasting compound. Outside of the human body, acetaldehyde is found, on average, in the highest concentration in a few different foods, such as sweet oranges, pineapples, and mandarin orange (clementine, tangerine) and in a lower concentration in . acetaldehyde has also been detected, but not quantified in several different foods, such as malabar plums, malus (crab apple), rose hips, natal plums, and medlars. This could make acetaldehyde a potential biomarker for the consumption of these foods. In condensation reactions, acetaldehyde is prochiral. Acetaldehyde is formally rated as a possible carcinogen (by IARC 2B) and is also a potentially toxic compound. Acetaldehyde has been found to be associated with several diseases such as alcoholism, ulcerative colitis, nonalcoholic fatty liver disease, and crohns disease; also acetaldehyde has been linked to the inborn metabolic disorders including aldehyde dehydrogenase deficiency (III) sulfate is used to reoxidize the mercury back to the mercury. Acetaldehyde was first observed by the Swedish pharmacist/chemist Carl Wilhelm Scheele (1774); it was then investigated by the French chemists Antoine François, comte de Fourcroy and Louis Nicolas Vauquelin (1800), and the German chemists Johann Wolfgang Döbereiner (1821, 1822, 1832) and Justus von Liebig (1835). At room temperature, acetaldehyde (CH3CHO) is more stable than vinyl alcohol (CH2CHOH) by 42.7 kJ/mol: Overall the keto-enol tautomerization occurs slowly but is catalyzed by acids. The level at which an average consumer could detect acetaldehyde is still considerably lower than any toxicity. Pathways of exposure include air, water, land, or groundwater, as well as drink and smoke. Acetaldehyde is also created by thermal degradation or ultraviolet photo-degradation of some thermoplastic polymers during or after manufacture. The water industry generally recognizes 20–40 ppb as the taste/odor threshold for acetaldehyde. The level at which an average consumer could detect acetaldehyde is still considerably lower than any toxicity.
Flavouring agent and adjuvant used to impart orange, apple and butter flavours; component of food flavourings added to milk products, baked goods, fruit juices, candy, desserts and soft drinks [DFC]

同义名列表

11 个代谢物同义名

Acetic aldehyde; Ethyl aldehyde; Acetaldehydes; acetaldehyde; Acetaldehyd; Azetaldehyd; Aldehyde; Ethanal; ch3cho; Acetaldehyde; Acetaldehyde



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(21)

BioCyc(40)

PlantCyc(1)

代谢反应

1473 个相关的代谢反应过程信息。

Reactome(214)

BioCyc(372)

WikiPathways(5)

Plant Reactome(296)

INOH(2)

PlantCyc(527)

COVID-19 Disease Map(1)

PathBank(56)

PharmGKB(0)

40 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, AOX1, BCL2, CAT, CYP2E1, ELANE, NFE2L2, TUBB4B, XDH
Peripheral membrane protein 4 ACHE, CYP1B1, CYP2E1, HSD17B6
Endosome membrane 1 TF
Endoplasmic reticulum membrane 3 BCL2, CYP1B1, CYP2E1
Nucleus 6 ACHE, ALB, BCL2, MPO, NFE2L2, TUBB4B
cytosol 12 ADH1B, ADH1C, AKR1A1, ALB, AOX1, BCL2, CAT, ELANE, GSR, NFE2L2, TUBB4B, XDH
phagocytic vesicle 1 ELANE
centrosome 2 ALB, NFE2L2
nucleoplasm 5 ADH1B, ADH1C, ATP2B1, MPO, NFE2L2
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 2 ACHE, ATP2B1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 ATP2B1
Synapse 3 ACHE, AKR1A1, ATP2B1
cell surface 3 ACHE, ELANE, TF
glutamatergic synapse 1 ATP2B1
Golgi apparatus 3 ACHE, ALB, NFE2L2
mitochondrial inner membrane 1 CYP2E1
neuromuscular junction 1 ACHE
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 2 AKR1A1, NFE2L2
Lysosome 1 MPO
plasma membrane 6 ACHE, ADH1B, ADH1C, ATP2B1, NFE2L2, TF
synaptic vesicle membrane 1 ATP2B1
Membrane 5 ACHE, ATP2B1, BCL2, CAT, CYP1B1
apical plasma membrane 2 AKR1A1, TF
basolateral plasma membrane 1 ATP2B1
extracellular exosome 10 AKR1A1, ALB, AOX1, ATP2B1, CAT, ELANE, GSR, MPO, TF, TUBB4B
Lumenal side 1 HSD17B6
endoplasmic reticulum 3 ALB, BCL2, HSD17B6
extracellular space 8 ACHE, AKR1A1, ALB, CXCL8, ELANE, MPO, TF, XDH
perinuclear region of cytoplasm 2 ACHE, TF
mitochondrion 4 BCL2, CAT, CYP1B1, GSR
protein-containing complex 3 ALB, BCL2, CAT
intracellular membrane-bounded organelle 6 ATP2B1, CAT, CYP1B1, CYP2E1, HSD17B6, MPO
Microsome membrane 3 CYP1B1, CYP2E1, HSD17B6
Secreted 4 ACHE, ALB, CXCL8, TF
extracellular region 8 ACHE, ALB, CAT, CXCL8, ELANE, MPO, TF, TUBB4B
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
basal part of cell 1 TF
mitochondrial matrix 2 CAT, GSR
Extracellular side 1 ACHE
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 GSR
Extracellular vesicle 1 TUBB4B
cytoplasmic vesicle 1 TF
microtubule cytoskeleton 1 TUBB4B
Early endosome 1 TF
clathrin-coated pit 1 TF
recycling endosome 1 TF
vesicle 1 TF
Apical cell membrane 1 AKR1A1
Mitochondrion inner membrane 1 CYP2E1
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 CAT
microtubule 1 TUBB4B
Peroxisome 2 CAT, XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 ELANE
secretory granule 2 ELANE, MPO
lateral plasma membrane 1 ATP2B1
Late endosome 1 TF
ciliary basal body 1 ALB
chromatin 1 NFE2L2
mediator complex 1 NFE2L2
cell projection 1 ATP2B1
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, TF
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
axonemal microtubule 1 TUBB4B
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
myelin sheath 1 BCL2
basal plasma membrane 1 TF
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, TF
HFE-transferrin receptor complex 1 TF
endoplasmic reticulum lumen 2 ALB, TF
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 ALB
specific granule lumen 1 ELANE
endocytic vesicle 1 TF
azurophil granule lumen 3 ELANE, MPO, TUBB4B
immunological synapse 1 ATP2B1
clathrin-coated endocytic vesicle membrane 1 TF
phagocytic vesicle lumen 1 MPO
synaptic cleft 1 ACHE
protein-DNA complex 1 NFE2L2
Cytoplasmic vesicle, phagosome 1 ELANE
vesicle coat 1 TF
catalase complex 1 CAT
BAD-BCL-2 complex 1 BCL2
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
dense body 1 TF


文献列表

  • Meiyue Qiu, Lili Yang, Zhiqiang Jiang, Yu Chen, Qinxin Liu, Xia Wang, Weidong Qu. Mixed exposure to haloacetaldehyde disinfection by-products exacerbates lipid aggregation in the liver of mice. Environmental pollution (Barking, Essex : 1987). 2024 Jun; 350(?):123971. doi: 10.1016/j.envpol.2024.123971. [PMID: 38641033]
  • Héléna Alamil, Marie-Lise Colsoul, Natacha Heutte, Marie Van Der Schueren, Laurence Galanti, Mathilde Lechevrel. Exocyclic DNA adducts and oxidative stress parameters: useful tools for biomonitoring exposure to aldehydes in smokers. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2024 May; 29(3):154-160. doi: 10.1080/1354750x.2024.2333361. [PMID: 38506499]
  • Pavel Pospíšil, Ankush Prasad, Julie Belková, Renuka Ramalingam Manoharan, Michaela Sedlářová. Formation of free acetaldehydes derived from lipid peroxidation in U937 monocyte-like cells. Biochimica et biophysica acta. General subjects. 2024 Feb; 1868(2):130527. doi: 10.1016/j.bbagen.2023.130527. [PMID: 38043915]
  • Elham Farghal Elkady, Haytham A Ayoub, Amina M Ibrahim. Molluscicidal activity of calcium borate nanoparticles with kodom ball-flower structure on hematological, histological and biochemical parameters of Eobania vermiculata snails. Pesticide biochemistry and physiology. 2024 Jan; 198(?):105716. doi: 10.1016/j.pestbp.2023.105716. [PMID: 38225073]
  • Shiyong Li, Chaodong Song, Hongyan Zhang, Yan Qin, Mingguo Jiang, Naikun Shen. Comparative Transcriptome Analysis Reveals the Molecular Mechanisms of Acetic Acid Reduction by Adding NaHSO3 in Actinobacillus succinogenes GXAS137. Polish journal of microbiology. 2023 Dec; 72(4):399-411. doi: 10.33073/pjm-2023-036. [PMID: 38000010]
  • Mengyun Xing, Kangkang Huang, Chen Zhang, Dujun Xi, Huifeng Luo, Jiabo Pei, Ruoxin Ruan, Hui Liu. Transcriptome Analysis Reveals the Molecular Mechanism and Responsive Genes of Waterlogging Stress in Actinidia deliciosa Planch Kiwifruit Plants. International journal of molecular sciences. 2023 Nov; 24(21):. doi: 10.3390/ijms242115887. [PMID: 37958870]
  • Rosario Zamora, Esmeralda Alcon, Francisco J Hidalgo. Malondialdehyde trapping by food phenolics. Food chemistry. 2023 Aug; 417(?):135915. doi: 10.1016/j.foodchem.2023.135915. [PMID: 36933433]
  • V D Prokopieva, T P Vetlugina. Features of oxidative stress in alcoholism. Biomeditsinskaia khimiia. 2023 Apr; 69(2):83-96. doi: 10.18097/pbmc20236902083. [PMID: 37132490]
  • Tomoya Kitakaze, Masako Inoue, Hitoshi Ashida. Aged Garlic Extract Prevents Alcohol-Induced Cytotoxicity through Induction of Aldehyde Dehydrogenase 2 in the Liver of Mice. Molecular nutrition & food research. 2023 Mar; ?(?):e2200627. doi: 10.1002/mnfr.202200627. [PMID: 36856009]
  • Kyeong Jin Kim, Soo-Yeon Park, Tae Gwon Park, Hyeon-Ju Park, Young-Jun Kim, Eun Ji Kim, Wonsuk Shin, Anhye Kim, Hyounggyoon Yoo, MinSon Kweon, Jihwan Jang, Su-Young Choi, Ji Yeon Kim. Noni fruit extract ameliorates alcohol-induced hangover symptoms by reducing the concentrations of alcohol and acetaldehyde in a Sprague Dawley rat model and a human intervention study. Food & function. 2023 Feb; 14(3):1750-1760. doi: 10.1039/d2fo02835b. [PMID: 36727425]
  • Mayrel Palestino-Domínguez, Alejandro Escobedo-Calvario, Soraya Salas-Silva, Moises Vergara-Mendoza, Veronica Souza-Arroyo, Roberto Lazzarini, Roxana Miranda-Labra, Leticia Bucio-Ortiz, María Concepción Gutiérrez-Ruiz, Luis E Gomez-Quiroz. Erk1/2 signaling mediates the HGF-induced protection against ethanol and acetaldehyde-induced toxicity in the pancreatic RINm5F cell line. Journal of biochemical and molecular toxicology. 2023 Jan; ?(?):e23302. doi: 10.1002/jbt.23302. [PMID: 36636782]
  • Michael A McQuillan, Alessia Ranciaro, Matthew E B Hansen, Shaohua Fan, William Beggs, Gurja Belay, Dawit Woldemeskel, Sarah A Tishkoff. Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans. Molecular biology and evolution. 2022 10; 39(10):. doi: 10.1093/molbev/msac183. [PMID: 36026493]
  • M Meischner, S Haberstroh, L E Daber, J Kreuzwieser, M C Caldeira, J-P Schnitzler, C Werner. Soil VOC emissions of a Mediterranean woodland are sensitive to shrub invasion. Plant biology (Stuttgart, Germany). 2022 Oct; 24(6):967-978. doi: 10.1111/plb.13445. [PMID: 35661369]
  • Oksal Macar, Tuğçe Kalefetoğlu Macar, Emine Yalçin, Kültiğin Çavuşoğlu, Ali Acar. Molecular docking and spectral shift supported toxicity profile of metaldehyde mollucide and the toxicity-reducing effects of bitter melon extract. Pesticide biochemistry and physiology. 2022 Oct; 187(?):105201. doi: 10.1016/j.pestbp.2022.105201. [PMID: 36127072]
  • Yuming Wei, Xuchao Yin, Huiting Wu, Mengjie Zhao, Junlan Huang, Jixin Zhang, Tiehan Li, Jingming Ning. Improving the flavor of summer green tea (Camellia sinensis L.) using the yellowing process. Food chemistry. 2022 Sep; 388(?):132982. doi: 10.1016/j.foodchem.2022.132982. [PMID: 35447593]
  • Martin H Rau, Paula Gaspar, Maiken Lund Jensen, Asger Geppel, Ana Rute Neves, Ahmad A Zeidan. Genome-Scale Metabolic Modeling Combined with Transcriptome Profiling Provides Mechanistic Understanding of Streptococcus thermophilus CH8 Metabolism. Applied and environmental microbiology. 2022 08; 88(16):e0078022. doi: 10.1128/aem.00780-22. [PMID: 35924931]
  • Xuan Yu, Xiaocong Zeng, Feng Xiao, Ri Chen, Pritam Sinharoy, Eric R Gross. E-cigarette aerosol exacerbates cardiovascular oxidative stress in mice with an inactive aldehyde dehydrogenase 2 enzyme. Redox biology. 2022 08; 54(?):102369. doi: 10.1016/j.redox.2022.102369. [PMID: 35751982]
  • Hannah E Lomzenski, Geoffrey M Thiele, Michael J Duryee, Sheau-Chiann Chen, Fei Ye, Daniel R Anderson, Ted R Mikuls, Michelle J Ormseth. Serum anti-malondialdehyde-acetaldehyde IgA antibody concentration improves prediction of coronary atherosclerosis beyond traditional risk factors in patients with rheumatoid arthritis. Scientific reports. 2022 06; 12(1):10547. doi: 10.1038/s41598-022-14954-9. [PMID: 35732827]
  • Gerhard Eisenbrand, Matthias Baum, Alexander T Cartus, Patrick Diel, Karl-Heinz Engel, Barbara Engeli, Bernd Epe, Tilman Grune, Sabine Guth, Dirk Haller, Volker Heinz, Michael Hellwig, Jan G Hengstler, Thomas Henle, Hans-Ulrich Humpf, Henry Jäger, Hans-Georg Joost, Sabine Kulling, Dirk W Lachenmeier, Alfonso Lampen, Marcel Leist, Angela Mally, Doris Marko, Ute Nöthlings, Elke Röhrdanz, Angelika Roth, Joachim Spranger, Richard Stadler, Stefan Vieths, Wim Wätjen, Pablo Steinberg. Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis. Archives of toxicology. 2022 06; 96(6):1905-1914. doi: 10.1007/s00204-022-03296-0. [PMID: 35504979]
  • Nagaraj M BhatB. Serum IgA levels and IgA/IgG ratio in Alcoholic Liver Disease. The Journal of the Association of Physicians of India. 2022 Apr; 70(4):11-12. doi: . [PMID: 35443491]
  • Zhongliang Liu, Baogui Xu, Yaping Ding, Xianjun Ding, Zuisu Yang. Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways. Bioengineered. 2022 04; 13(4):9357-9368. doi: 10.1080/21655979.2022.2054224. [PMID: 35387552]
  • Michael J Duryee, Dahn L Clemens, Patrick J Opperman, Geoffrey M Thiele, Logan M Duryee, Robert P Garvin, Daniel R Anderson. Malondialdehyde-Acetaldehyde Modified (MAA) Proteins Differentially Effect the Inflammatory Response in Macrophage, Endothelial Cells and Animal Models of Cardiovascular Disease. International journal of molecular sciences. 2021 Nov; 22(23):. doi: 10.3390/ijms222312948. [PMID: 34884754]
  • Weifeng Lin, Louis P Conway, Miroslav Vujasinovic, J-Matthias Löhr, Daniel Globisch. Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites. Angewandte Chemie (International ed. in English). 2021 10; 60(43):23232-23240. doi: 10.1002/anie.202107101. [PMID: 34339587]
  • Harriet Rumgay, Neil Murphy, Pietro Ferrari, Isabelle Soerjomataram. Alcohol and Cancer: Epidemiology and Biological Mechanisms. Nutrients. 2021 Sep; 13(9):. doi: 10.3390/nu13093173. [PMID: 34579050]
  • Aleksandra Ostapiuk, Łukasz Kurach, Maciej Strzemski, Jacek Kurzepa, Anna Hordyjewska. Evaluation of Antioxidative Mechanisms In Vitro and Triterpenes Composition of Extracts from Silver Birch (Betula pendula Roth) and Black Birch (Betula obscura Kotula) Barks by FT-IR and HPLC-PDA. Molecules (Basel, Switzerland). 2021 Jul; 26(15):. doi: 10.3390/molecules26154633. [PMID: 34361786]
  • Jiaman Liu, Bo Teng, Xiaofeng Zhang, Minghui Dai, Yue Lin, Yang Liu, Jacqui M McRae. Anthocyanins from purple passion fruit (Passiflora edulia Sims) rind-An innovative source for nonbleachable pigment production. Journal of food science. 2021 Jul; 86(7):2978-2989. doi: 10.1111/1750-3841.15807. [PMID: 34155646]
  • Yasser Abobakr, Amira F Gad, Hamza S Abou-Elnasr, Gaber M Abdelgalil, Hamdy I Hussein, Shady Selim. Contact toxicity and biochemical impact of metaldehyde against the white garden snail Theba pisana (Müller, 1774). Pest management science. 2021 Jul; 77(7):3208-3215. doi: 10.1002/ps.6359. [PMID: 33683007]
  • Xiao Liu, Hui-Ming Fan, Dong-He Liu, Jing Liu, Yan Shen, Jing Zhang, Jun Wei, Chun-Lei Wang. Transcriptome and Metabolome Analyses Provide Insights into the Watercore Disorder on "Akibae" Pear Fruit. International journal of molecular sciences. 2021 May; 22(9):. doi: 10.3390/ijms22094911. [PMID: 34066340]
  • Timothy J Tse, Fina B Nelson, Martin J T Reaney. Analyses of Commercially Available Alcohol-Based Hand Rubs Formulated with Compliant and Non-Compliant Ethanol. International journal of environmental research and public health. 2021 04; 18(7):. doi: 10.3390/ijerph18073766. [PMID: 33916568]
  • Tae-Joong Lim, Sanghyun Lim, Jong Hyun Yoon, Myung Jun Chung. Effects of multi-species probiotic supplementation on alcohol metabolism in rats. Journal of microbiology (Seoul, Korea). 2021 Apr; 59(4):417-425. doi: 10.1007/s12275-021-0573-2. [PMID: 33779954]
  • Lexiao Jin, Jordan Lynch, Andre Richardson, Pawel Lorkiewicz, Shweta Srivastava, Whitney Theis, Gregg Shirk, Alexis Hand, Aruni Bhatnagar, Sanjay Srivastava, Daniel J Conklin. Electronic cigarette solvents, pulmonary irritation, and endothelial dysfunction: role of acetaldehyde and formaldehyde. American journal of physiology. Heart and circulatory physiology. 2021 04; 320(4):H1510-H1525. doi: 10.1152/ajpheart.00878.2020. [PMID: 33543686]
  • Koji Ishida, Kosuke Kaji, Shinya Sato, Hiroyuki Ogawa, Hirotetsu Takagi, Hiroaki Takaya, Hideto Kawaratani, Kei Moriya, Tadashi Namisaki, Takemi Akahane, Hitoshi Yoshiji. Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. The Journal of nutritional biochemistry. 2021 03; 89(?):108573. doi: 10.1016/j.jnutbio.2020.108573. [PMID: 33388347]
  • Alison D Petro, Joseph Dougherty, Bryant R England, Harlan Sayles, Michael J Duryee, Carlos D Hunter, Joel M Kremer, Dimitrios A Pappas, William H Robinson, Jeffrey R Curtis, Geoffrey M Thiele, Ted R Mikuls. Associations between an expanded autoantibody profile and treatment responses to biologic therapies in patients with rheumatoid arthritis. International immunopharmacology. 2021 Feb; 91(?):107260. doi: 10.1016/j.intimp.2020.107260. [PMID: 33360371]
  • Su-Mei Kou, Rong Jin, Ying-Ying Wu, Jing-Wen Huang, Qiu-Yun Zhang, Ning-Jing Sun, Yong Yang, Chang-Fei Guan, Wen-Qiu Wang, Chang-Qing Zhu, Qing-Gang Zhu, Xue-Ren Yin. Transcriptome Analysis Revealed the Roles of Carbohydrate Metabolism on Differential Acetaldehyde Production Capacity in Persimmon Fruit in Response to High-CO2 Treatment. Journal of agricultural and food chemistry. 2021 Jan; 69(2):836-845. doi: 10.1021/acs.jafc.0c06001. [PMID: 33416310]
  • Takahito Takase, Tsudoi Toyoda, Naoyuki Kobayashi, Takashi Inoue, Tomoko Ishijima, Keiko Abe, Hiroshi Kinoshita, Youichi Tsuchiya, Shinji Okada. Dietary iso-α-acids prevent acetaldehyde-induced liver injury through Nrf2-mediated gene expression. PloS one. 2021; 16(2):e0246327. doi: 10.1371/journal.pone.0246327. [PMID: 33544749]
  • Hsin-Wen Liang, Tsung-Yuan Yang, Chia-Sheng Teng, Yi-Ju Lee, Meng-Hsun Yu, Huei-Jane Lee, Li-Sung Hsu, Chau-Jong Wang. Mulberry leaves extract ameliorates alcohol-induced liver damages through reduction of acetaldehyde toxicity and inhibition of apoptosis caused by oxidative stress signals. International journal of medical sciences. 2021; 18(1):53-64. doi: 10.7150/ijms.50174. [PMID: 33390773]
  • Ted R Mikuls, Jess Edison, Elizabeth Meeshaw, Harlan Sayles, Bryant R England, Michael J Duryee, Carlos D Hunter, Lindsay B Kelmenson, Laura Kay Moss, Marie L Feser, Brandie Wagner, Mark C Parish, Kevin D Deane, Geoffrey M Thiele. Autoantibodies to Malondialdehyde-Acetaldehyde Are Detected Prior to Rheumatoid Arthritis Diagnosis and After Other Disease Specific Autoantibodies. Arthritis & rheumatology (Hoboken, N.J.). 2020 12; 72(12):2025-2029. doi: 10.1002/art.41424. [PMID: 32621635]
  • Kai Peng, Dan Guo, Qianqian Lou, Xiaoyun Lu, Jian Cheng, Jing Qiao, Lina Lu, Tao Cai, Yuwan Liu, Huifeng Jiang. Synthesis of Ligustrazine from Acetaldehyde by a Combined Biological-Chemical Approach. ACS synthetic biology. 2020 11; 9(11):2902-2908. doi: 10.1021/acssynbio.0c00113. [PMID: 33156612]
  • Anne Landmesser, Gerhard Scherer, Nikola Pluym, Reinhard Niessner, Max Scherer. A novel quantification method for sulfur-containing biomarkers of formaldehyde and acetaldehyde exposure in human urine and plasma samples. Analytical and bioanalytical chemistry. 2020 Nov; 412(27):7535-7546. doi: 10.1007/s00216-020-02888-y. [PMID: 32840653]
  • Grażyna Kubiak-Tomaszewska, Piotr Tomaszewski, Jan Pachecka, Marta Struga, Wioletta Olejarz, Magdalena Mielczarek-Puta, Grażyna Nowicka. Molecular mechanisms of ethanol biotransformation: enzymes of oxidative and nonoxidative metabolic pathways in human. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Oct; 50(10):1180-1201. doi: 10.1080/00498254.2020.1761571. [PMID: 32338108]
  • J A Custodio-Mendoza, J Aja-Macaya, I M Valente, J A Rodrigues, P J Almeida, R A Lorenzo, A M Carro. Determination of malondialdehyde, acrolein and four other products of lipid peroxidation in edible oils by Gas-Diffusion Microextraction combined with Dispersive Liquid-Liquid Microextraction. Journal of chromatography. A. 2020 Sep; 1627(?):461397. doi: 10.1016/j.chroma.2020.461397. [PMID: 32823102]
  • Hardik Naik Jinal, Natrajan Amaresan. In Silico and In Vitro Analyses of Glucosamine and Indole Acetaldehyde Inhibit Pathogenic Regulator Gene phcA of Ralstonia solanacearum, a Causative Agent of Bacterial Wilt of Tomato. Applied biochemistry and biotechnology. 2020 Sep; 192(1):230-242. doi: 10.1007/s12010-020-03328-4. [PMID: 32367442]
  • Harumi Uto-Kondo, Ayaka Sakurai, Kazuki Ogawa, Yusuke Yamaguchi, Takeshi Saito, Hitomi Kumagai. Suppressive Effect of Shiitake Extract on Plasma Ethanol Elevation. Nutrients. 2020 Aug; 12(9):. doi: 10.3390/nu12092647. [PMID: 32878044]
  • Danyun Xu, Qing Liu, Gang Chen, Zhiqiang Yan, Honghong Hu. Aldehyde dehydrogenase ALDH3F1 involvement in flowering time regulation through histone acetylation modulation on FLOWERING LOCUS C. Journal of integrative plant biology. 2020 Aug; 62(8):1080-1092. doi: 10.1111/jipb.12893. [PMID: 31829514]
  • Sibren Haesen, Ümare Cöl, Wouter Schurgers, Lize Evens, Maxim Verboven, Ronald B Driesen, Annelies Bronckaers, Ivo Lambrichts, Dorien Deluyker, Virginie Bito. Glycolaldehyde-modified proteins cause adverse functional and structural aortic remodeling leading to cardiac pressure overload. Scientific reports. 2020 07; 10(1):12220. doi: 10.1038/s41598-020-68974-4. [PMID: 32699285]
  • Kaisa Rissanen, Anni Vanhatalo, Yann Salmon, Jaana Bäck, Teemu Hölttä. Stem emissions of monoterpenes, acetaldehyde and methanol from Scots pine (Pinus sylvestris L.) affected by tree-water relations and cambial growth. Plant, cell & environment. 2020 07; 43(7):1751-1765. doi: 10.1111/pce.13778. [PMID: 32335919]
  • Geoffrey M Thiele, Michael J Duryee, Carlos D Hunter, Bryant R England, Benjamin S Fletcher, Eric C Daubach, Taylor P Pospisil, Lynell W Klassen, Ted R Mikuls. Immunogenic and inflammatory responses to citrullinated proteins are enhanced following modification with malondialdehyde-acetaldehyde adducts. International immunopharmacology. 2020 Jun; 83(?):106433. doi: 10.1016/j.intimp.2020.106433. [PMID: 32224441]
  • Xueshuang Li, Man Li, Zhen Peng, Kewen Zheng, Li Xu, Junguo Dong, Guofa Ren, Ping Cheng. Reaction kinetic study of nonthermal plasma continuous degradation of acetone in a closed-loop reactor. Chemosphere. 2020 Jun; 249(?):126215. doi: 10.1016/j.chemosphere.2020.126215. [PMID: 32088460]
  • Paula Silva, Norbert Latruffe, Giovanni de Gaetano. Wine Consumption and Oral Cavity Cancer: Friend or Foe, Two Faces of Janus. Molecules (Basel, Switzerland). 2020 May; 25(11):. doi: 10.3390/molecules25112569. [PMID: 32486484]
  • Aldo Tava, Elisa Biazzi, Domenico Ronga, Pinarosa Avato. Identification of the Volatile Components of Galium verum L. and Cruciata leavipes Opiz from the Western Italian Alps. Molecules (Basel, Switzerland). 2020 May; 25(10):. doi: 10.3390/molecules25102333. [PMID: 32429453]
  • Ana Flávia Machado Botelho, Amanda Milhomem Donato Machado, Rayanne Henrique Santana da Silva, Amanda Carvalho Faria, Lucas Santos Machado, Heloa Santos, Sandro de Melo Braga, Bruno Benetti Junta Torres, Marina Pacheco Miguel, Andrea Rodrigues Chaves, Marília Martins Melo. Fatal metaldehyde poisoning in a dog confirmed by gas chromatography. BMC veterinary research. 2020 May; 16(1):139. doi: 10.1186/s12917-020-02348-w. [PMID: 32414366]
  • Xiaohua Zhao, Hong Ma, Qiusha Pan, Haiyi Wang, Xingkai Qian, Peifang Song, Liwei Zou, Mingqing Mao, Shuyue Xia, Guangbo Ge, Ling Yang. Theophylline Acetaldehyde as the Initial Product in Doxophylline Metabolism in Human Liver. Drug metabolism and disposition: the biological fate of chemicals. 2020 05; 48(5):345-352. doi: 10.1124/dmd.119.089565. [PMID: 32086296]
  • Hyun-Jin Kim, Semi Kim, Jin-Sook Seo, Gun-Won Bae, Keun-Nam Kim, Ju-Seop Kang. Effect of Single-Dose, Oral Enzymatic Porcine Placental Extract on Pharmacokinetics of Alcohol and Liver Function in Rats. Alcoholism, clinical and experimental research. 2020 05; 44(5):1018-1024. doi: 10.1111/acer.14319. [PMID: 32154587]
  • Deolinda Santinha, Anna Klopot, Igor Marques, Ewa Ellis, Carl Jorns, Helene Johansson, Tânia Melo, Per Antonson, Tomas Jakobsson, Vítor Félix, Jan-Åke Gustafsson, Maria Rosário Domingues, Agneta Mode, Luisa A Helguero. Lipidomic analysis of human primary hepatocytes following LXR activation with GW3965 identifies AGXT2L1 as a main target associated to changes in phosphatidylethanolamine. The Journal of steroid biochemistry and molecular biology. 2020 04; 198(?):105558. doi: 10.1016/j.jsbmb.2019.105558. [PMID: 31783151]
  • Dian Huang, Chen Yu, Zongze Shao, Minmin Cai, Guangyu Li, Longyu Zheng, Ziniu Yu, Jibin Zhang. Identification and Characterization of Nematicidal Volatile Organic Compounds from Deep-Sea Virgibacillus dokdonensis MCCC 1A00493. Molecules (Basel, Switzerland). 2020 02; 25(3):. doi: 10.3390/molecules25030744. [PMID: 32050419]
  • Rosario Zamora, Cristina M Lavado-Tena, Francisco J Hidalgo. Oligomerization of reactive carbonyls in the presence of ammonia-producing compounds: A route for the production of pyridines in foods. Food chemistry. 2020 Jan; 304(?):125284. doi: 10.1016/j.foodchem.2019.125284. [PMID: 31476546]
  • Ligia Shimabukuro Okuda, Rodrigo Tallada Iborra, Paula Ramos Pinto, Ubiratan Fabres Machado, Maria Lucia Corrêa-Giannella, Russell Pickford, Tom Woods, Margaret Anne Brimble, Kerry-Anne Rye, Marisa Passarelli. Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages. Mediators of inflammation. 2020; 2020(?):6515401. doi: 10.1155/2020/6515401. [PMID: 32410861]
  • Anderson Weber, Fabio Rodrigo Thewes, Marc Sellwig, Auri Brackmann, Jens Norbert Wünsche, Dominikus Kittemann, Daniel Alexandre Neuwald. Dynamic controlled atmosphere: Impact of elevated storage temperature on anaerobic metabolism and quality of 'Nicoter' apples. Food chemistry. 2019 Nov; 298(?):125017. doi: 10.1016/j.foodchem.2019.125017. [PMID: 31260967]
  • Jossiê Zamperetti Donadel, Fabio Rodrigo Thewes, Rogerio de Oliveira Anese, Erani Eliseu Schultz, Magno Roberto Pasquetti Berghetti, Vagner Ludwig, Bruna Klein, Alexandre José Cichoski, Juliano Smanioto Barin, Vanderlei Both, Auri Brackmann, Roger Wagner. Key volatile compounds of 'Fuji Kiku' apples as affected by the storage conditions and shelf life: Correlation between volatile emission by intact fruit and juice extracted from the fruit. Food research international (Ottawa, Ont.). 2019 11; 125(?):108625. doi: 10.1016/j.foodres.2019.108625. [PMID: 31554098]
  • Sana Waris, Safia Habib, Shifa Khan, Tasneem Kausar, Shahid M Naeem, Shahid A Siddiqui, Moinuddin, Asif Ali. Molecular docking explores heightened immunogenicity and structural dynamics of acetaldehyde human immunoglobulin G adduct. IUBMB life. 2019 10; 71(10):1522-1536. doi: 10.1002/iub.2078. [PMID: 31185142]
  • Bryant R England, Michael J Duryee, Punyasha Roul, Tina D Mahajan, Namrata Singh, Jill A Poole, Dana P Ascherman, Liron Caplan, M Kristen Demoruelle, Kevin D Deane, Lynell W Klassen, Geoffrey M Thiele, Ted R Mikuls. Malondialdehyde-Acetaldehyde Adducts and Antibody Responses in Rheumatoid Arthritis-Associated Interstitial Lung Disease. Arthritis & rheumatology (Hoboken, N.J.). 2019 09; 71(9):1483-1493. doi: 10.1002/art.40900. [PMID: 30933423]
  • Bo Teng, Yoji Hayasaka, Paul A Smith, Keren A Bindon. Effect of Grape Seed and Skin Tannin Molecular Mass and Composition on the Rate of Reaction with Anthocyanin and Subsequent Formation of Polymeric Pigments in the Presence of Acetaldehyde. Journal of agricultural and food chemistry. 2019 Aug; 67(32):8938-8949. doi: 10.1021/acs.jafc.9b01498. [PMID: 31361121]
  • Zhengyi Chen, Gongke Li, Zhuomin Zhang. Miniaturized array gas membrane separation strategy for rapid analysis of complex samples by surface-enhanced Raman scattering. Analytica chimica acta. 2019 Aug; 1065(?):29-39. doi: 10.1016/j.aca.2019.03.031. [PMID: 31005148]
  • Li Chen, Xiaojuan Xiong, Xingyun Hou, Hua Wei, Jianxiu Zhai, Tianyi Xia, Xiaobin Gong, Shouhong Gao, Ge Feng, Xia Tao, Feng Zhang, Wansheng Chen. Wuzhi capsule regulates chloroacetaldehyde pharmacokinetics behaviour and alleviates high-dose cyclophosphamide-induced nephrotoxicity and neurotoxicity in rats. Basic & clinical pharmacology & toxicology. 2019 Aug; 125(2):142-151. doi: 10.1111/bcpt.13211. [PMID: 30793490]
  • Xiang Sheng, Fahmi Himo. Enzymatic Pictet-Spengler Reaction: Computational Study of the Mechanism and Enantioselectivity of Norcoclaurine Synthase. Journal of the American Chemical Society. 2019 07; 141(28):11230-11238. doi: 10.1021/jacs.9b04591. [PMID: 31265268]
  • Fabio Vivarelli, Donatella Canistro, Silvia Cirillo, Vladimiro Cardenia, Maria Teresa Rodriguez-Estrada, Moreno Paolini. Impairment of testicular function in electronic cigarette (e-cig, e-cigs) exposed rats under low-voltage and nicotine-free conditions. Life sciences. 2019 Jul; 228(?):53-65. doi: 10.1016/j.lfs.2019.04.059. [PMID: 31029780]
  • Hui Han, Yuxin He, Heather Johnson, Pratibha Mishra, Harrison Lee, Cheng Ji. Protective Effects of Facilitated Removal of Blood Alcohol and Acetaldehyde Against Liver Injury in Animal Models Fed Alcohol and Anti-HIV Drugs. Alcoholism, clinical and experimental research. 2019 06; 43(6):1091-1102. doi: 10.1111/acer.14034. [PMID: 30908665]
  • Minmin Wang, Lei Zhang, Kyung Hwan Boo, Eunsook Park, Georgia Drakakaki, Florence Zakharov. PDC1, a pyruvate/α-ketoacid decarboxylase, is involved in acetaldehyde, propanal and pentanal biosynthesis in melon (Cucumis melo L.) fruit. The Plant journal : for cell and molecular biology. 2019 04; 98(1):112-125. doi: 10.1111/tpj.14204. [PMID: 30556202]
  • Xueshuang Li, Teng Guo, Zhen Peng, Li Xu, Junguo Dong, Ping Cheng, Zhen Zhou. Real-time monitoring and quantification of organic by-products and mechanism study of acetone decomposition in a dielectric barrier discharge reactor. Environmental science and pollution research international. 2019 Mar; 26(7):6773-6781. doi: 10.1007/s11356-019-04127-z. [PMID: 30628003]
  • Daniel Dörler, Agnes Scheucher, Johann G Zaller. Efficacy of chemical and biological slug control measures in response to watering and earthworms. Scientific reports. 2019 02; 9(1):2954. doi: 10.1038/s41598-019-39585-5. [PMID: 30814638]
  • Ki Hoon Kim, Abid Farooq, Min Young Song, Sang-Chul Jung, Ki-Joon Jeon, JiHyeon Song, Chang Hyun Ko, Jungho Jae, Young-Kwon Park. Acetaldehyde removal and increased H2/CO gas yield from biomass gasification over metal-loaded Kraft lignin char catalyst. Journal of environmental management. 2019 Feb; 232(?):330-335. doi: 10.1016/j.jenvman.2018.11.054. [PMID: 30496962]
  • Glenn D Castle, Graham A Mills, Anthony Gravell, Alister Leggatt, Jeff Stubbs, Richard Davis, Gary R Fones. Comparison of different monitoring methods for the measurement of metaldehyde in surface waters. Environmental monitoring and assessment. 2019 Jan; 191(2):75. doi: 10.1007/s10661-019-7221-x. [PMID: 30648204]
  • Amarjeet Kumar, Vithal Balavant Kudachikar. Development, characterisation and efficacy evaluation of biochemical fungicidal formulations for postharvest control of anthracnose (Colletotrichum gloeosporioides Penz) disease in mango. Journal of microencapsulation. 2019 Jan; 36(1):83-95. doi: 10.1080/02652048.2019.1600593. [PMID: 30920322]
  • Che-Hong Chen, Julio C B Ferreira, Daria Mochly-Rosen. ALDH2 and Cardiovascular Disease. Advances in experimental medicine and biology. 2019; 1193(?):53-67. doi: 10.1007/978-981-13-6260-6_3. [PMID: 31368097]
  • Moustafa El-Shenawy, Mohamed T Fouad, Laila K Hassan, Faten L Seleet, Mahmoud Abd El-Aziz. A Probiotic Beverage Made from Tiger-nut Extract and Milk Permeate. Pakistan journal of biological sciences : PJBS. 2019 Jan; 22(4):180-187. doi: 10.3923/pjbs.2019.180.187. [PMID: 31930819]
  • Ippo Otoyama, Hironobu Hamada, Tatsushi Kimura, Haruchi Namba, Kiyokazu Sekikawa, Norimichi Kamikawa, Teruki Kajiwara, Fumiya Aizawa, Yoshinobu M Sato. L-cysteine improves blood fluidity impaired by acetaldehyde: In vitro evaluation. PloS one. 2019; 14(3):e0214585. doi: 10.1371/journal.pone.0214585. [PMID: 30925182]
  • Jan Günther, Axel Schmidt, Jonathan Gershenzon, Tobias G Köllner. Phenylacetaldehyde synthase 2 does not contribute to the constitutive formation of 2-phenylethyl-β-D-glucopyranoside in poplar. Plant signaling & behavior. 2019; 14(11):1668233. doi: 10.1080/15592324.2019.1668233. [PMID: 31532355]
  • Renny Reji Mammen, Johannah Natinga Mulakal, Ratheesh Mohanan, Balu Maliakel, Krishnakumar Illathu Madhavamenon. Clove Bud Polyphenols Alleviate Alterations in Inflammation and Oxidative Stress Markers Associated with Binge Drinking: A Randomized Double-Blinded Placebo-Controlled Crossover Study. Journal of medicinal food. 2018 Nov; 21(11):1188-1196. doi: 10.1089/jmf.2017.4177. [PMID: 30234415]
  • K Rissanen, T Hölttä, J Bäck. Transpiration directly regulates the emissions of water-soluble short-chained OVOCs. Plant, cell & environment. 2018 10; 41(10):2288-2298. doi: 10.1111/pce.13318. [PMID: 29676016]
  • Lahiru N Jayakody, Timothy Lee Turner, Eun Ju Yun, In Iok Kong, Jing-Jing Liu, Yong-Su Jin. Expression of Gre2p improves tolerance of engineered xylose-fermenting Saccharomyces cerevisiae to glycolaldehyde under xylose metabolism. Applied microbiology and biotechnology. 2018 Sep; 102(18):8121-8133. doi: 10.1007/s00253-018-9216-x. [PMID: 30027490]
  • Joan Domingo-Espín, Oktawia Nilsson, Katja Bernfur, Rita Del Giudice, Jens O Lagerstedt. Site-specific glycations of apolipoprotein A-I lead to differentiated functional effects on lipid-binding and on glucose metabolism. Biochimica et biophysica acta. Molecular basis of disease. 2018 09; 1864(9 Pt B):2822-2834. doi: 10.1016/j.bbadis.2018.05.014. [PMID: 29802959]
  • Pablo Giménez-Gómez, Mercedes Pérez-Hernández, María Dolores Gutiérrez-López, Rebeca Vidal, Cristina Abuin-Martínez, Esther O'Shea, María Isabel Colado. Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens. Neuropharmacology. 2018 06; 135(?):581-591. doi: 10.1016/j.neuropharm.2018.04.016. [PMID: 29705534]
  • Mio Takayama, Brian Waters, Hiroshi Fujii, Kenji Hara, Masayuki Kashiwagi, Aya Matsusue, Natsuki Ikematsu, Shin-Ichi Kubo. Subarachnoid hemorrhage in a Japanese cocaine abuser: Cocaine-related sudden death. Legal medicine (Tokyo, Japan). 2018 May; 32(?):43-47. doi: 10.1016/j.legalmed.2018.02.008. [PMID: 29518652]
  • Ramona B Rudnick, Qian Chen, Emma Diletta Stea, Andrea Hartmann, Nikolina Papac-Milicevic, Fermin Person, Michael Wiesener, Christoph J Binder, Thorsten Wiech, Christine Skerka, Peter F Zipfel. FHR5 Binds to Laminins, Uses Separate C3b and Surface-Binding Sites, and Activates Complement on Malondialdehyde-Acetaldehyde Surfaces. Journal of immunology (Baltimore, Md. : 1950). 2018 04; 200(7):2280-2290. doi: 10.4049/jimmunol.1701641. [PMID: 29483359]
  • Harumi Uto-Kondo, Ayumu Hase, Yusuke Yamaguchi, Ayaka Sakurai, Makoto Akao, Takeshi Saito, Hitomi Kumagai. S-Allyl-L-cysteine sulfoxide, a garlic odor precursor, suppresses elevation in blood ethanol concentration by accelerating ethanol metabolism and preventing ethanol absorption from gut. Bioscience, biotechnology, and biochemistry. 2018 Apr; 82(4):724-731. doi: 10.1080/09168451.2018.1447357. [PMID: 29616890]
  • Liuyi Hao, Qian Sun, Wei Zhong, Wenliang Zhang, Xinguo Sun, Zhanxiang Zhou. Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease. Redox biology. 2018 04; 14(?):626-636. doi: 10.1016/j.redox.2017.11.005. [PMID: 29156373]
  • Tagnon D Missihoun, Simeon O Kotchoni. Aldehyde dehydrogenases and the hypothesis of a glycolaldehyde shunt pathway of photorespiration. Plant signaling & behavior. 2018 03; 13(3):e1449544. doi: 10.1080/15592324.2018.1449544. [PMID: 29521550]
  • Michael J Duryee, Benjamin M Wiese, Jordan R Bowman, Jared D Vanlandingham, Lynell W Klassen, Geoffrey E Thiele, Carlos D Hunter, Daniel R Anderson, Ted R Mikuls, Geoffrey M Thiele. Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2018 03; 314(3):G418-G430. doi: 10.1152/ajpgi.00183.2017. [PMID: 29351393]
  • Ted R Mikuls, Michael J Duryee, Bryant R England, Daniel R Anderson, Michelene Hearth-Holmes, Kaihong Su, Kaleb Michaud, Jeffrey B Payne, Harlan Sayles, Carlos Hunter, Jacob D McGowan, Lynell W Klassen, Geoffrey M Thiele. Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions. International immunopharmacology. 2018 Mar; 56(?):113-118. doi: 10.1016/j.intimp.2018.01.022. [PMID: 29414640]
  • Teng Guo, Xueshuang Li, Jianquan Li, Zhen Peng, Li Xu, Junguo Dong, Ping Cheng, Zhen Zhou. On-line quantification and human health risk assessment of organic by-products from the removal of toluene in air using non-thermal plasma. Chemosphere. 2018 Mar; 194(?):139-146. doi: 10.1016/j.chemosphere.2017.11.173. [PMID: 29202266]
  • Alexander Klaus, Tim Baldensperger, Roman Fiedler, Matthias Girndt, Marcus A Glomb. Influence of Transketolase-Catalyzed Reactions on the Formation of Glycolaldehyde and Glyoxal Specific Posttranslational Modifications under Physiological Conditions. Journal of agricultural and food chemistry. 2018 Feb; 66(6):1498-1508. doi: 10.1021/acs.jafc.7b05472. [PMID: 29400466]
  • Le Yang, Chenyang Yan, Feng Zhang, Bo Jiang, Shouhong Gao, Youtian Liang, Lifeng Huang, Wansheng Chen. Effects of ketoconazole on cyclophosphamide metabolism: evaluation of CYP3A4 inhibition effect using the in vitro and in vivo models. Experimental animals. 2018 Feb; 67(1):71-82. doi: 10.1538/expanim.17-0048. [PMID: 29129847]
  • Xue Zou, Yan Lu, Lei Xia, Yating Zhang, Aiyue Li, Hongmei Wang, Chaoqun Huang, Chengyin Shen, Yannan Chu. Detection of Volatile Organic Compounds in a Drop of Urine by Ultrasonic Nebulization Extraction Proton Transfer Reaction Mass Spectrometry. Analytical chemistry. 2018 02; 90(3):2210-2215. doi: 10.1021/acs.analchem.7b04563. [PMID: 29281786]
  • Max L Senders, Xuchu Que, Young Seok Cho, Calvin Yeang, Hannah Groenen, Francois Fay, Claudia Calcagno, Anu E Meerwaldt, Simone Green, Phuong Miu, Mark E Lobatto, Thomas Reiner, Zahi A Fayad, Joseph L Witztum, Willem J M Mulder, Carlos Pérez-Medina, Sotirios Tsimikas. PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis. Journal of the American College of Cardiology. 2018 01; 71(3):321-335. doi: 10.1016/j.jacc.2017.11.036. [PMID: 29348025]
  • Young-Moo Choo, Pingxi Xu, Justin K Hwang, Fangfang Zeng, Kaiming Tan, Ganga Bhagavathy, Kamlesh R Chauhan, Walter S Leal. Reverse chemical ecology approach for the identification of an oviposition attractant for Culex quinquefasciatus. Proceedings of the National Academy of Sciences of the United States of America. 2018 01; 115(4):714-719. doi: 10.1073/pnas.1718284115. [PMID: 29311316]
  • Qi He, Yan Diao, Tingting Zhao, Baoyu Hou, Linel Darrel Ngokana, Huan Liang, Junhui Nie, Peizhu Tan, Hui Huang, Yanze Li, Lin Qi, Yuanyuan Zhao, Ying Liu, Xu Gao, Lingyun Zhou. SREBP1c mediates the effect of acetaldehyde on Cidea expression in Alcoholic fatty liver Mice. Scientific reports. 2018 01; 8(1):1200. doi: 10.1038/s41598-018-19466-z. [PMID: 29352167]
  • Jianxiu Zhai, Feng Zhang, Shouhong Gao, Li Chen, Ge Feng, Jun Yin, Wansheng Chen. Schisandra chinensis extract decreases chloroacetaldehyde production in rats and attenuates cyclophosphamide toxicity in liver, kidney and brain. Journal of ethnopharmacology. 2018 Jan; 210(?):223-231. doi: 10.1016/j.jep.2017.08.020. [PMID: 28821392]
  • Michael P Torrens-Spence, Tomáš Pluskal, Fu-Shuang Li, Valentina Carballo, Jing-Ke Weng. Complete Pathway Elucidation and Heterologous Reconstitution of Rhodiola Salidroside Biosynthesis. Molecular plant. 2018 01; 11(1):205-217. doi: 10.1016/j.molp.2017.12.007. [PMID: 29277428]
  • Mikael Kyrklund, Outi Kummu, Jari Kankaanpää, Ramin Akhi, Antti Nissinen, S Pauliina Turunen, Pirkko Pussinen, Chunguang Wang, Sohvi Hörkkö. Immunization with gingipain A hemagglutinin domain of Porphyromonas gingivalis induces IgM antibodies binding to malondialdehyde-acetaldehyde modified low-density lipoprotein. PloS one. 2018; 13(1):e0191216. doi: 10.1371/journal.pone.0191216. [PMID: 29329335]