Isovaleraldehyde (BioDeep_00000004238)

 

Secondary id: BioDeep_00000405606, BioDeep_00000861471

human metabolite blood metabolite BioNovoGene_Lab2019 natural product


代谢物信息卡片


3-Methyl-butyraldehyde

化学式: C5H10O (86.0732)
中文名称: 异戊醛, 3-甲基丁醛
谱图信息: 最多检出来源 Homo sapiens(blood) 45.61%

分子结构信息

SMILES: C(CC=O)(C)C
InChI: InChI=1S/C5H10O/c1-5(2)3-4-6/h4-5H,3H2,1-2H3

描述信息

Iso-Valeraldehyde, also known as isoamyl aldehyde or 3-methyl-butanal, belongs to the class of organic compounds known as alpha-hydrogen aldehydes. These are aldehydes with the general formula HC(H)(R)C(=O)H, where R is an organyl group. Iso-Valeraldehyde exists in all eukaryotes, ranging from yeast to humans. Iso-Valeraldehyde is an aldehydic, chocolate, and ethereal tasting compound. Iso-Valeraldehyde is found, on average, in the highest concentration within a few different foods, such as milk (cow), beers, and taco and in a lower concentration in kohlrabis, corns, and tortilla. Iso-Valeraldehyde has also been detected, but not quantified, in several different foods, such as muskmelons, highbush blueberries, fenugreeks, hazelnuts, and dills. This could make iso-valeraldehyde a potential biomarker for the consumption of these foods. A methylbutanal that is butanal substituted by a methyl group at position 3. Iso-Valeraldehyde, with regard to humans, has been found to be associated with several diseases such as ulcerative colitis, crohns disease, perillyl alcohol administration for cancer treatment, and hepatic encephalopathy; iso-valeraldehyde has also been linked to the inborn metabolic disorder celiac disease.
Occurs in orange, bergamot, lemon, sandalwood, citronella, peppermint, eucalyptus and other oilsand is also in apple, grape, peach cider, vinegar, wines, wheatbreads, scallops and ginger

同义名列表

23 个代谢物同义名

3-Methyl-butyraldehyde; 3-Methylbutyraldehyde; Isovaleric aldehyde; Isovalerylaldehyde; 3-Methyl-1-butanal; 3-Methylbutan-1-al; beta-Methylbutanal; 2-Methylbutanal-4; iso-Valeraldehyde; Isovaleraldehyde; 3-Methyl-butanal; Isoamyl aldehyde; Β-methylbutanal; Isopentaldehyde; 3-Methylbutanal; Isoamylaldehyde; b-Methylbutanal; Methyl butanal; Iso-C4H9CHO; Isopentanal; Isovaleral; 3-Methylbutanal; 3-Methylbutanal



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

9 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(8)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

105 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ACTC1, BDNF, CRYZ, CSNK2B, MYLK, NQO1, PMP2, RBP1, SDCBP2
Peripheral membrane protein 1 HSD17B6
Nucleus 7 CSNK2B, EBF1, EMX2, MYBL1, NQO1, PMP2, RBP1
cytosol 10 ACTC1, AKR1A1, CRYZ, CSNK2B, MB, MYLK, NQO1, PMP2, RBP1, SDCBP2
dendrite 2 BDNF, NQO1
nucleoplasm 4 CSNK2B, MYBL1, RBP1, SDCBP2
Cell membrane 2 CHRNA7, SDCBP2
Cleavage furrow 1 MYLK
lamellipodium 2 ACTC1, MYLK
Cell projection, axon 1 EMX2
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 CHRNA7
Synapse 4 AKR1A1, CHRNA7, MYLK, NQO1
cell surface 2 CD200, TNFRSF10B
glutamatergic synapse 2 ACTC1, RBP1
Golgi apparatus 2 ATRN, SDCBP2
neuronal cell body 2 CD200, NQO1
postsynapse 1 CHRNA7
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 2 AKR1A1, NQO1
plasma membrane 7 ATRN, CD200, CHRNA7, MYLK, RBP1, SDCBP2, TNFRSF10B
Membrane 6 ACTC1, BDNF, CD200, CHRNA7, NQO1, TNFRSF10B
apical plasma membrane 1 AKR1A1
axon 3 BDNF, CD200, EMX2
extracellular exosome 8 ACTC1, AKR1A1, ATRN, CRYZ, CSNK2B, MB, PMP2, SDCBP2
Lumenal side 1 HSD17B6
endoplasmic reticulum 1 HSD17B6
extracellular space 4 ACTC1, AKR1A1, ATRN, BDNF
perinuclear region of cytoplasm 1 BDNF
mitochondrion 3 CRYZ, MCAT, RBP1
intracellular membrane-bounded organelle 1 HSD17B6
Microsome membrane 1 HSD17B6
filopodium 1 ACTC1
Single-pass type I membrane protein 1 ATRN
Secreted 1 BDNF
extracellular region 2 BDNF, CSNK2B
Single-pass membrane protein 1 CD200
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 MCAT
actin cytoskeleton 1 MYLK
nucleolus 1 SDCBP2
sarcoplasm 1 MB
postsynaptic membrane 1 CHRNA7
Apical cell membrane 1 AKR1A1
Cell projection, lamellipodium 1 MYLK
Cytoplasm, cytoskeleton 1 ACTC1
focal adhesion 1 ACTC1
PML body 1 CSNK2B
nuclear speck 1 SDCBP2
Postsynaptic cell membrane 1 CHRNA7
sarcomere 1 ACTC1
neuron projection 2 CD200, CHRNA7
chromatin 3 CSNK2B, EBF1, EMX2
Nucleus, nucleolus 1 SDCBP2
actin filament 1 ACTC1
blood microparticle 1 ACTC1
[Isoform 3]: Secreted 1 ATRN
Lipid droplet 1 RBP1
I band 1 ACTC1
Nucleus, nucleoplasm 1 SDCBP2
Nucleus speckle 1 SDCBP2
cell body 3 ACTC1, CD200, RBP1
myelin sheath 1 PMP2
stress fiber 1 MYLK
plasma membrane raft 1 CHRNA7
ficolin-1-rich granule lumen 1 CSNK2B
secretory granule lumen 1 CSNK2B
endoplasmic reticulum lumen 1 BDNF
transcription repressor complex 1 RBP1
calyx of Held 1 RBP1
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
Sin3-type complex 1 RBP1
[Isoform 1]: Cell membrane 1 ATRN
Cytoplasm, sarcoplasm 1 MB
acetylcholine-gated channel complex 1 CHRNA7
protein kinase CK2 complex 1 CSNK2B
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF


文献列表

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