α-Zearalenol (BioDeep_00000418824)

Main id: BioDeep_00000003886

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


alpha-Zearalenol

化学式: C18H24O5 (320.1623654)
中文名称: ALPHA-玉米赤霉烯醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCCC(CCCC=CC2=C(C(=CC(=C2)O)O)C(=O)O1)O
InChI: InChI=1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3/b7-3+/t12-,14+/m0/s1

描述信息

同义名列表

3 个代谢物同义名

alpha-Zearalenol; trans-Zearalenol; α-Zearalenol



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Honglei Qu, Yunduo Zheng, Ruifen Kang, Yulong Feng, Pengshuai Li, Yantao Wang, Jie Cheng, Cheng Ji, Wenqiong Chai, Qiugang Ma. Toxicokinetics of Zearalenone following Oral Administration in Female Dezhou Donkeys. Toxins. 2024 Jan; 16(1):. doi: 10.3390/toxins16010051. [PMID: 38251267]
  • Jiao Tian, Jiaoyang Luo, Jiaan Qin, Yudan Wang, Xinqi Sun, Jing Zhang, Tongwei Ke, Mengyue Guo, Haonan Ruan, Fang An, Meihua Yang. Preparation of a broad-specificity antibody against zearalenone and its primary analogues and development of immunoassay of Coicis Semen and related products. Journal of food science. 2023 May; ?(?):. doi: 10.1111/1750-3841.16600. [PMID: 37195191]
  • Neda Alvarez-Ortega, Karina Caballero-Gallardo, Cristina Juan, Ana Juan-Garcia, Jesus Olivero-Verbel. Cytoprotective, Antiproliferative, and Anti-Oxidant Potential of the Hydroethanolic Extract of Fridericia chica Leaves on Human Cancer Cell Lines Exposed to α- and β-Zearalenol. Toxins. 2023 Jan; 15(1):. doi: 10.3390/toxins15010036. [PMID: 36668856]
  • Qian Lu, Ming Sui, Ya-Wen Luo, Jiao-Yang Luo, Mei-Hua Yang. Further insight into the potential toxicity of zearalenone-14-glucoside based on toxicokinetics, tissue distribution, transformation, and excretion in rats. Ecotoxicology and environmental safety. 2022 Nov; 246(?):114184. doi: 10.1016/j.ecoenv.2022.114184. [PMID: 36244169]
  • Jennifer Duringer, Rajarshi Mazumder, Valerie Palmer, A Morrie Craig, Peter Spencer. Case-Control Study of Nodding Syndrome in Acholiland: Urinary Multi-Mycotoxin Screening. Toxins. 2021 04; 13(5):. doi: 10.3390/toxins13050313. [PMID: 33925470]
  • Ana Juan-García, Giovanni Caprioli, Gianni Sagratini, Jordi Mañes, Cristina Juan. Coffee Silverskin and Spent Coffee Suitable as Neuroprotectors against Cell Death by Beauvericin and α-Zearalenol: Evaluating Strategies of Treatment. Toxins. 2021 02; 13(2):. doi: 10.3390/toxins13020132. [PMID: 33579040]
  • Tim Birr, Tolke Jensen, Nils Preußke, Frank D Sönnichsen, Marthe De Boevre, Sarah De Saeger, Mario Hasler, Joseph-Alexander Verreet, Holger Klink. Occurrence of Fusarium Mycotoxins and Their Modified Forms in Forage Maize Cultivars. Toxins. 2021 02; 13(2):. doi: 10.3390/toxins13020110. [PMID: 33540691]
  • Christiane Gruber-Dorninger, Johannes Faas, Barbara Doupovec, Markus Aleschko, Christian Stoiber, Andreas Höbartner-Gußl, Karin Schöndorfer, Manuela Killinger, Qendrim Zebeli, Dian Schatzmayr. Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme. Toxins. 2021 01; 13(2):. doi: 10.3390/toxins13020084. [PMID: 33499402]
  • Shupeng Yang, Yanshen Li, Marthe De Boevre, Sarah De Saeger, Jinhui Zhou, Yi Li, Huiyan Zhang, Feifei Sun. Toxicokinetics of α-zearalenol and its masked form in rats and the comparative biotransformation in liver microsomes from different livestock and humans. Journal of hazardous materials. 2020 Jul; 393(?):121403. doi: 10.1016/j.jhazmat.2019.121403. [PMID: 32143155]
  • Ecem Fatma Karaman, Müjdat Zeybel, Sibel Ozden. Evaluation of the epigenetic alterations and gene expression levels of HepG2 cells exposed to zearalenone and α-zearalenol. Toxicology letters. 2020 Jun; 326(?):52-60. doi: 10.1016/j.toxlet.2020.02.015. [PMID: 32119988]
  • Silvia W Gratz, Valerie Currie, Gary Duncan, Diane Jackson. Multimycotoxin Exposure Assessment in UK Children Using Urinary Biomarkers-A Pilot Survey. Journal of agricultural and food chemistry. 2020 Jan; 68(1):351-357. doi: 10.1021/acs.jafc.9b03964. [PMID: 31826612]
  • Barbara Gzyl-Malcher, Elżbieta Rudolphi-Skórska, Apolonia Sieprawska, Maria Filek. Manganese protects wheat from the mycotoxin zearalenone and its derivatives. Scientific reports. 2019 10; 9(1):14214. doi: 10.1038/s41598-019-50664-5. [PMID: 31578385]
  • José L Hidalgo-Ruiz, Roberto Romero-González, José Luis Martínez Vidal, Antonia Garrido Frenich. A rapid method for the determination of mycotoxins in edible vegetable oils by ultra-high performance liquid chromatography-tandem mass spectrometry. Food chemistry. 2019 Aug; 288(?):22-28. doi: 10.1016/j.foodchem.2019.03.003. [PMID: 30902285]
  • Amelie Catteuw, Nathan Broekaert, Siegrid De Baere, Marianne Lauwers, Elke Gasthuys, Bart Huybrechts, Alfons Callebaut, Lada Ivanova, Silvio Uhlig, Marthe De Boevre, Sarah De Saeger, Ronette Gehring, Mathias Devreese, Siska Croubels. Insights into In Vivo Absolute Oral Bioavailability, Biotransformation, and Toxicokinetics of Zearalenone, α-Zearalenol, β-Zearalenol, Zearalenone-14-glucoside, and Zearalenone-14-sulfate in Pigs. Journal of agricultural and food chemistry. 2019 Mar; 67(12):3448-3458. doi: 10.1021/acs.jafc.8b05838. [PMID: 30807145]
  • Nurshad Ali, Gisela H Degen. Urinary biomarkers of exposure to the mycoestrogen zearalenone and its modified forms in German adults. Archives of toxicology. 2018 08; 92(8):2691-2700. doi: 10.1007/s00204-018-2261-5. [PMID: 29980802]
  • Yue Song, Pinggu Wu, Zhengyan Hu, Lijun Yang, Ying Chen. [Determination of zearalenone and α-zearalenol in vegetable oil and grain products by C_(18)-Al_2O_3 solid phase extraction column purification coupled with ultra-performance liquid chromatography tandem mass spectrometry]. Wei sheng yan jiu = Journal of hygiene research. 2018 Jul; 47(4):615-620. doi: . [PMID: 30081990]
  • Anna Chiara Nittoli, Susan Costantini, Angela Sorice, Francesca Capone, Roberto Ciarcia, Stefania Marzocco, Alfredo Budillon, Lorella Severino. Effects of α-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach. Metabolomics : Official journal of the Metabolomic Society. 2018 02; 14(3):33. doi: 10.1007/s11306-018-1330-3. [PMID: 30830360]
  • M Takagi, S Uno, E Kokushi, F Sato, Mmp Wijayagunawardane, J Fink-Gremmels. Measurement of urinary concentrations of the mycotoxins zearalenone and sterigmatocystin as biomarkers of exposure in mares. Reproduction in domestic animals = Zuchthygiene. 2018 Feb; 53(1):68-73. doi: 10.1111/rda.13054. [PMID: 28921680]
  • Silvia W Gratz, Reshma Dinesh, Tomoya Yoshinari, Grietje Holtrop, Anthony J Richardson, Gary Duncan, Susan MacDonald, Antony Lloyd, Jonathan Tarbin. Masked trichothecene and zearalenone mycotoxins withstand digestion and absorption in the upper GI tract but are efficiently hydrolyzed by human gut microbiota in vitro. Molecular nutrition & food research. 2017 04; 61(4):. doi: 10.1002/mnfr.201600680. [PMID: 27921366]
  • Sabina B Binder, Heidi E Schwartz-Zimmermann, Elisabeth Varga, Gerlinde Bichl, Herbert Michlmayr, Gerhard Adam, Franz Berthiller. Metabolism of Zearalenone and Its Major Modified Forms in Pigs. Toxins. 2017 02; 9(2):. doi: 10.3390/toxins9020056. [PMID: 28208710]
  • Intidhar Ben Salem, Manel Boussabbeh, Alexandre Prola, Arnaud Guilbert, Hassen Bacha, Christophe Lemaire, Salwa Abid-Essefi. Crocin protects human embryonic kidney cells (HEK293) from α- and β-Zearalenol-induced ER stress and apoptosis. Environmental science and pollution research international. 2016 Aug; 23(15):15504-14. doi: 10.1007/s11356-016-6741-y. [PMID: 27121014]
  • Fabiola Pizzo, Francesca Caloni, Luis F Schutz, Morgan L Totty, Leon J Spicer. Individual and combined effects of deoxynivalenol and α-zearalenol on cell proliferation and steroidogenesis of granulosa cells in cattle. Environmental toxicology and pharmacology. 2015 Nov; 40(3):722-8. doi: 10.1016/j.etap.2015.08.025. [PMID: 26425942]
  • Urara Nakamura, Hiroya Kadokawa. The nonsteroidal mycoestrogen zearalenone and its five metabolites suppress LH secretion from the bovine anterior pituitary cells via the estradiol receptor GPR30 in vitro. Theriogenology. 2015 Nov; 84(8):1342-9. doi: 10.1016/j.theriogenology.2015.07.014. [PMID: 26255852]
  • Constanze Pietsch, Susanne Kersten, Hana Valenta, Sven Dänicke, Carsten Schulz, Patricia Burkhardt-Holm, Ranka Junge. Effects of Dietary Exposure to Zearalenone (ZEN) on Carp (Cyprinus carpio L.). Toxins. 2015 Aug; 7(9):3465-80. doi: 10.3390/toxins7093465. [PMID: 26343724]
  • M Denli, J C Blandon, M E Guynot, S Salado, J F Pérez. Efficacy of activated diatomaceous clay in reducing the toxicity of zearalenone in rats and piglets. Journal of animal science. 2015 Feb; 93(2):637-45. doi: 10.2527/jas.2014-7356. [PMID: 26020748]
  • Sven Dänicke, Christina Keese, Ulrich Meyer, Alexander Starke, Asako Kinoshita, Jürgen Rehage. Zearalenone (ZEN) metabolism and residue concentrations in physiological specimens of dairy cows exposed long-term to ZEN-contaminated diets differing in concentrate feed proportions. Archives of animal nutrition. 2014 Dec; 68(6):492-506. doi: 10.1080/1745039x.2014.973236. [PMID: 25348458]
  • Johannes Gerding, Benedikt Cramer, Hans-Ulrich Humpf. Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach. Molecular nutrition & food research. 2014 Dec; 58(12):2358-68. doi: 10.1002/mnfr.201400406. [PMID: 25243722]
  • H Belhassen, I Jiménez-Díaz, R Ghali, H Ghorbel, J M Molina-Molina, N Olea, A Hedili. Validation of a UHPLC-MS/MS method for quantification of zearalenone, α-zearalenol, β-zearalenol, α-zearalanol, β-zearalanol and zearalanone in human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2014 Jul; 962(?):68-74. doi: 10.1016/j.jchromb.2014.05.019. [PMID: 24907545]
  • Hui Zhang, Qi Sun, Teng Liu, Lu Ma, Panpan Zhen, Ke Wang, Lingqiao Lu, Xin Liu, Xin Zhang, Dandan Song, Xiaoyun Zuo, Huirong Liu, Wen Wang. Alleviation of plasma homocysteine level by phytoestrogen α-zearalanol might be related to the reduction of cystathionine β-synthase nitration. BioMed research international. 2014; 2014(?):143192. doi: 10.1155/2014/143192. [PMID: 24783194]
  • Dwaipayan Mukherjee, Steven G Royce, Jocelyn A Alexander, Brian Buckley, Sastry S Isukapalli, Elisa V Bandera, Helmut Zarbl, Panos G Georgopoulos. Physiologically-based toxicokinetic modeling of zearalenone and its metabolites: application to the Jersey girl study. PloS one. 2014; 9(12):e113632. doi: 10.1371/journal.pone.0113632. [PMID: 25474635]
  • Gordon S Shephard, Hester-Mari Burger, Lucia Gambacorta, Yun Yun Gong, Rudolf Krska, John P Rheeder, Michele Solfrizzo, Chou Srey, Michael Sulyok, Angelo Visconti, Benedikt Warth, Liana van der Westhuizen. Multiple mycotoxin exposure determined by urinary biomarkers in rural subsistence farmers in the former Transkei, South Africa. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013 Dec; 62(?):217-25. doi: 10.1016/j.fct.2013.08.040. [PMID: 23985452]
  • Emmanuel Njumbe Ediage, José Diana Di Mavungu, Suquan Song, Isabelle Sioen, Sarah De Saeger. Multimycotoxin analysis in urines to assess infant exposure: a case study in Cameroon. Environment international. 2013 Jul; 57-58(?):50-9. doi: 10.1016/j.envint.2013.04.002. [PMID: 23669720]
  • Wei-Jun Kong, Hong-Hong Shen, Xiao-Fei Zhang, Xiao-Li Yang, Feng Qiu, Zhen Ou-yang, Mei-Hua Yang. Analysis of zearalenone and α-zearalenol in 100 foods and medicinal plants determined by HPLC-FLD and positive confirmation by LC-MS-MS. Journal of the science of food and agriculture. 2013 May; 93(7):1584-90. doi: 10.1002/jsfa.5926. [PMID: 23096594]
  • Rentsenkhand Sambuu, Mitsuhiro Takagi, Zhao Namula, Masahiro Nii, Masayasu Taniguchi, Seiich Uno, Emiko Kokushi, Chenga Tshering, Regiane Rodrigues dos Santos, Johanna Fink-Gremmels, Takeshige Otoi. Effects of long-term in vitro exposure of ejaculated boar sperm to zearalenone and α-zearalenol in sperm liquid storage medium. Animal science journal = Nihon chikusan Gakkaiho. 2013 Jan; 84(1):28-34. doi: 10.1111/j.1740-0929.2012.01033.x. [PMID: 23302079]
  • Elisa V Bandera, Urmila Chandran, Brian Buckley, Yong Lin, Sastry Isukapalli, Ian Marshall, Melony King, Helmut Zarbl. Urinary mycoestrogens, body size and breast development in New Jersey girls. The Science of the total environment. 2011 Nov; 409(24):5221-7. doi: 10.1016/j.scitotenv.2011.09.029. [PMID: 21975003]
  • Mario Thevis, Gregor Fusshöller, Wilhelm Schänzer. Zeranol: doping offence or mycotoxin? A case-related study. Drug testing and analysis. 2011 Nov; 3(11-12):777-83. doi: 10.1002/dta.352. [PMID: 22095651]
  • Michele Solfrizzo, Lucia Gambacorta, Veronica M T Lattanzio, Stephen Powers, Angelo Visconti. Simultaneous LC-MS/MS determination of aflatoxin M1, ochratoxin A, deoxynivalenol, de-epoxydeoxynivalenol, α and β-zearalenols and fumonisin B1 in urine as a multi-biomarker method to assess exposure to mycotoxins. Analytical and bioanalytical chemistry. 2011 Nov; 401(9):2831-41. doi: 10.1007/s00216-011-5354-z. [PMID: 21892639]
  • C Frizzell, D Ndossi, S Verhaegen, E Dahl, G Eriksen, M Sørlie, E Ropstad, M Muller, C T Elliott, L Connolly. Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis. Toxicology letters. 2011 Oct; 206(2):210-7. doi: 10.1016/j.toxlet.2011.07.015. [PMID: 21803136]
  • Zhanhui Wang, Pengjie Luo, Linli Cheng, Suxia Zhang, Jianzhong Shen. Hapten-antibody recognition studies in competitive immunoassay of α-zearalanol analogs by computational chemistry and Pearson Correlation analysis. Journal of molecular recognition : JMR. 2011 Sep; 24(5):815-23. doi: 10.1002/jmr.1121. [PMID: 21812055]
  • Zheng Han, Yiping Ren, Hailong Zhou, Lianjun Luan, Zengxuan Cai, Yongjiang Wu. A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Feb; 879(5-6):411-20. doi: 10.1016/j.jchromb.2010.12.028. [PMID: 21242113]
  • S Dänicke, M Beyer, G Breves, H Valenta, H-U Humpf. Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2010 Nov; 27(11):1558-65. doi: 10.1080/19440049.2010.501036. [PMID: 20677033]
  • Mei Dong, Phitsanu Tulayakul, Jun-You Li, Ke-Su Dong, Noboru Manabe, Susumu Kumagai. Metabolic conversion of zearalenone to alpha-zearalenol by goat tissues. The Journal of veterinary medical science. 2010 Mar; 72(3):307-12. doi: 10.1292/jvms.09-0122. [PMID: 19959886]
  • S Abid-Essefi, C Bouaziz, E El Golli-Bennour, Z Ouanes, Hassen Bacha. Comparative study of toxic effects of zearalenone and its two major metabolites alpha-zearalenol and beta-zearalenol on cultured human Caco-2 cells. Journal of biochemical and molecular toxicology. 2009 Jul; 23(4):233-43. doi: 10.1002/jbt.20284. [PMID: 19705349]
  • Zouhour Ouanes-Ben Othmen, Emna El Golli, Salwa Abid-Essefi, Hassen Bacha. Cytotoxicity effects induced by Zearalenone metabolites, alpha Zearalenol and beta Zearalenol, on cultured Vero cells. Toxicology. 2008 Oct; 252(1-3):72-7. doi: 10.1016/j.tox.2008.07.065. [PMID: 18755238]
  • Giovanni Ranzenigo, Francesca Caloni, Fausto Cremonesi, Pauline Y Aad, Leon J Spicer. Effects of Fusarium mycotoxins on steroid production by porcine granulosa cells. Animal reproduction science. 2008 Aug; 107(1-2):115-30. doi: 10.1016/j.anireprosci.2007.06.023. [PMID: 17656051]
  • Francesco Massart, Valentina Meucci, Giuseppe Saggese, Giulio Soldani. High growth rate of girls with precocious puberty exposed to estrogenic mycotoxins. The Journal of pediatrics. 2008 May; 152(5):690-5, 695.e1. doi: 10.1016/j.jpeds.2007.10.020. [PMID: 18410776]
  • Jian Ying Yang, Guo Xin Wang, Jia Li Liu, Jing Jing Fan, Sheng Cui. Toxic effects of zearalenone and its derivatives alpha-zearalenol on male reproductive system in mice. Reproductive toxicology (Elmsford, N.Y.). 2007 Nov; 24(3-4):381-7. doi: 10.1016/j.reprotox.2007.05.009. [PMID: 17628394]
  • Niccolo Hartmann, Marianne Erbs, Felix E Wettstein, René P Schwarzenbach, Thomas D Bucheli. Quantification of estrogenic mycotoxins at the ng/L level in aqueous environmental samples using deuterated internal standards. Journal of chromatography. A. 2007 Jan; 1138(1-2):132-40. doi: 10.1016/j.chroma.2006.10.045. [PMID: 17084850]
  • H Malekinejad, B Colenbrander, J Fink-Gremmels. Hydroxysteroid dehydrogenases in bovine and porcine granulosa cells convert zearalenone into its hydroxylated metabolites alpha-zearalenol and beta-zearalenol. Veterinary research communications. 2006 May; 30(4):445-53. doi: 10.1007/s11259-006-3325-1. [PMID: 16502112]
  • S Dänicke, E Swiech, L Buraczewska, K-H Ueberschär. Kinetics and metabolism of zearalenone in young female pigs. Journal of animal physiology and animal nutrition. 2005 Aug; 89(7-8):268-76. doi: 10.1111/j.1439-0396.2005.00516.x. [PMID: 15972077]
  • Naoko Takahashi-Ando, Takeshi Tokai, Hiroshi Hamamoto, Isamu Yamaguchi, Makoto Kimura. Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene. Applied microbiology and biotechnology. 2005 Jun; 67(6):838-44. doi: 10.1007/s00253-004-1816-y. [PMID: 15630583]
  • Stefanie Weber, Prisca Leuschner, Peter Kämpfer, Wolfgang Dott, Juliane Hollender. Degradation of estradiol and ethinyl estradiol by activated sludge and by a defined mixed culture. Applied microbiology and biotechnology. 2005 Apr; 67(1):106-12. doi: 10.1007/s00253-004-1693-4. [PMID: 15290133]
  • W Zwierzchowski, M Przybyłowicz, K Obremski, L Zielonka, E Skorska-Wyszyńska, M Gajecka, M Polak, E Jakimiuk, B Jana, L Rybarczyk, M Gajecki. Level of zearalenone in blood serum and lesions in ovarian follicles of sexually immature gilts in the course of zearalenone micotoxicosis. Polish journal of veterinary sciences. 2005; 8(3):209-18. doi: . [PMID: 16180582]
  • Shunling Dai, Jinhong Duan, Yuan Lu, Yihua Zhang, Jinxuan Cheng, Jun Ren, Xiaoyuan Zhao, Yunqing Wu, Yue Yu, Pingping Zuo, Yiyong Wu, Qinsheng Ge. Phytoestrogen alpha-zearalanol inhibits atherogenesis and improves lipid profile in ovariectomized cholesterol-fed rabbits. Endocrine. 2004 Nov; 25(2):121-9. doi: 10.1385/endo:25:2:121. [PMID: 15711025]
  • Shunling Dai, Jinhong Duan, Yuan Lu, Jinxuan Cheng, Jun Ren, Wenhui Deng, Yiyong Wu. Alpha-Zearalanol, a phytoestrogen for cardiovascular therapy. Endocrine. 2004 Nov; 25(2):117-9. doi: 10.1385/endo:25:2:117. [PMID: 15711024]
  • F M Launay, P B Young, S S Sterk, M H Blokland, D G Kennedy. Confirmatory assay for zeranol, taleranol and the Fusarium spp. toxins in bovine urine using liquid chromatography-tandem mass spectrometry. Food additives and contaminants. 2004 Jan; 21(1):52-62. doi: 10.1080/02652030310001636930. [PMID: 14744680]
  • K M Cooper, L Ribeiro, P Alves, V Vozikis, S Tsitsamis, G Alfredsson, T Lövgren, M Tuomola, H Takalo, A Iitia, S S Sterk, M Blokland, D G Kennedy. Interlaboratory ring test of time-resolved fluoroimmunoassays for zeranol and alpha-zearalenol and comparison with zeranol test kits. Food additives and contaminants. 2003 Sep; 20(9):804-12. doi: 10.1080/0265203031000156097. [PMID: 13129775]
  • Kazimierz Pasternak, Małgorzata Kiełczykowska, Małgorzata Sztanke, Andrzej Borzecki. The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Magnesium research. 2003 Jun; 16(2):106-10. doi: NULL. [PMID: 12892380]
  • K M Cooper, M Tuomola, S Lahdenperä, T Lövgren, C T Elliott, D G Kennedy. Development and validation of dry reagent time-resolved fluoroimmunoassays for zeranol and alpha-zearalenol to assist in distinguishing zeranol abuse from Fusarium spp. toxin contamination in bovine urine. Food additives and contaminants. 2002 Dec; 19(12):1130-7. doi: 10.1080/0265203021000012411. [PMID: 12623673]
  • Peter Zöllner, Justus Jodlbauer, Martina Kleinova, Hermann Kahlbacher, Thomas Kuhn, Werner Hochsteiner, Wolfgang Lindner. Concentration levels of zearalenone and its metabolites in urine, muscle tissue, and liver samples of pigs fed with mycotoxin-contaminated oats. Journal of agricultural and food chemistry. 2002 Apr; 50(9):2494-501. doi: 10.1021/jf0113631. [PMID: 11958611]
  • D Altavilla, A Saitta, M Galeano, G Squadrito, D Marino, L Minutoli, G Calapai, B Deodato, R D'Anna, F Corrado, A P Caputi, F Squadrito. The phytoestrogen alpha-zearalenol reverses endothelial dysfunction induced by oophorectomy in rats. Laboratory investigation; a journal of technical methods and pathology. 2001 Feb; 81(2):125-32. doi: 10.1038/labinvest.3780219. [PMID: 11232633]
  • S Dänicke, K H Ueberschär, I Halle, H Valenta, G Flachowsky. Excretion kinetics and metabolism of zearalenone in broilers in dependence on a detoxifying agent. Archiv fur Tierernahrung. 2001; 55(4):299-313. doi: 10.1080/17450390109386199. [PMID: 12357591]
  • T Celius, J B Matthews, J P Giesy, T R Zacharewski. Quantification of rainbow trout (Oncorhynchus mykiss) zona radiata and vitellogenin mRNA levels using real-time PCR after in vivo treatment with estradiol-17 beta or alpha-zearalenol. The Journal of steroid biochemistry and molecular biology. 2000 Dec; 75(2-3):109-19. doi: 10.1016/s0960-0760(00)00165-5. [PMID: 11226827]
  • A Arukwe, T Grotmol, T B Haugen, F R Knudsen, A Goksøyr. Fish model for assessing the in vivo estrogenic potency of the mycotoxin zearalenone and its metabolites. The Science of the total environment. 1999 Sep; 236(1-3):153-61. doi: 10.1016/s0048-9697(99)00275-2. [PMID: 10535150]
  • G M Ware, Y Zhao, S S Kuan, A S Carman. Preparative method for isolating alpha-zearalenol and zearalenone using extracting disk. Journal of AOAC International. 1999 Jan; 82(1):90-4. doi: 10.1093/jaoac/82.1.90. [PMID: 10028676]
  • M F Ruh, Y Bi, L Cox, D Berk, A C Howlett, C J Bellone. Effect of environmental estrogens on IL-1beta promoter activity in a macrophage cell line. Endocrine. 1998 Oct; 9(2):207-11. doi: 10.1385/endo:9:2:207. [PMID: 9867255]
  • D G Kennedy, J D McEvoy, W J Blanchflower, S A Hewitt, A Cannavan, W J McCaughey, C T Elliott. Possible naturally occurring zeranol in bovine bile in Northern Ireland. Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B. 1995 Oct; 42(8):509-12. doi: 10.1111/j.1439-0450.1995.tb00742.x. [PMID: 8578925]
  • R Bagnati, M Paleologo Oriundi, V Russo, M Danese, F Berti, R Fanelli. Determination of zeranol and beta-zearalanol in calf urine by immunoaffinity extraction and gas chromatography-mass spectrometry after repeated administration of zeranol. Journal of chromatography. 1991 Apr; 564(2):493-502. doi: 10.1016/0378-4347(91)80518-h. [PMID: 1874854]
  • J Plasencia, C J Mirocha, R J Pawlosky, J F Smith. Analysis of zearalenone and alpha-zearalenol in urine of ruminants using gas chromatography-tandem mass spectrometry. Journal - Association of Official Analytical Chemists. 1990 Nov; 73(6):973-80. doi: . [PMID: 2149724]
  • D B Prelusky, R M Warner, H L Trenholm. Sensitive analysis of the mycotoxin zearalenone and its metabolites in biological fluids by high-performance liquid chromatography alpha. Journal of chromatography. 1989 Sep; 494(?):267-77. doi: 10.1016/s0378-4347(00)82675-4. [PMID: 2531151]
  • D W Fitzpatrick, L D Arbuckle, A M Hassen. Zearalenone metabolism and excretion in the rat: effect of different doses. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1988 Aug; 23(4):343-54. doi: 10.1080/03601238809372610. [PMID: 2973490]
  • M Olsen, C J Mirocha, H K Abbas, B Johansson. Metabolism of high concentrations of dietary zearalenone by young male turkey poults. Poultry science. 1986 Oct; 65(10):1905-10. doi: 10.3382/ps.0651905. [PMID: 2948167]
  • M E Olsen, H I Pettersson, K A Sandholm, K H Kiessling. Quantitative liquid chromatographic method using fluorescence detection for determining zearalenone and its metabolites in blood plasma and urine. Journal - Association of Official Analytical Chemists. 1985 Jul; 68(4):632-5. doi: . [PMID: 3161869]
  • M Olsen, K Malmlöf, H Pettersson, K Sandholm, K H Kiessling. Plasma and urinary levels of zearalenone and alpha-zearalenol in a prepubertal gilt fed zearalenone. Acta pharmacologica et toxicologica. 1985 Mar; 56(3):239-43. doi: 10.1111/j.1600-0773.1985.tb01282.x. [PMID: 3160216]
  • L J James, L G McGirr, T K Smith. High pressure liquid chromatography of zearalenone and zearalenols in rat urine and liver. Journal - Association of Official Analytical Chemists. 1982 Jan; 65(1):8-13. doi: NULL. [PMID: 6460020]
  • H L Trenholm, R M Warner, E R Farnworth. High performance liquid chromatographic method using fluorescence detention for quantitative analysis of zearalenone and alpha-zearalenol in blood plasma. Journal - Association of Official Analytical Chemists. 1981 Mar; 64(2):302-10. doi: NULL. [PMID: 6453116]