D-Glucosamine (BioDeep_00000412599)

Main id: BioDeep_00000001863

 

PANOMIX_OTCML-2023


代谢物信息卡片


2-Amino-2-deoxyhexopyranose

化学式: C6H13NO5 (179.0793688)
中文名称: 2-氨基-2-脱氧-D-吡喃葡萄糖
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1C(C(C(C(O1)O)N)O)O)O
InChI: InChI=1S/C6H13NO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1,7H2/t2-,3-,4-,5-,6?/m1/s1

描述信息

M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].

同义名列表

4 个代谢物同义名

2-Amino-2-deoxyhexopyranose; D-Glucosamine; Chitosamine; Glucosamine



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuan Zhang, Line A Borch, Niklas H Fischer, Morten Meldal. Hydrodynamic Control of Alzheimer Aβ Fibrillation with Glucosaminic Acid Containing Click-Cyclized β-Bodies. Journal of the American Chemical Society. 2024 Jan; 146(4):2654-2662. doi: 10.1021/jacs.3c12118. [PMID: 38126710]
  • Sang-Min Kim, Dong Yeol Kim, Jiwon Park, Young-Ah Moon, Inn-Oc Han. Glucosamine increases macrophage lipid accumulation by regulating the mammalian target of rapamycin signaling pathway. BMB reports. 2023 Nov; ?(?):. doi: . [PMID: 37964636]
  • Akshayaa Venkataraghavan, Julian G Schwerdt, Stephen D Tyerman, Maria Hrmova. Barley Nodulin 26-like Intrinsic Protein permeates water, metalloids, saccharides, and ion pairs due to structural plasticity and diversification. The Journal of biological chemistry. 2023 Oct; ?(?):105410. doi: 10.1016/j.jbc.2023.105410. [PMID: 37913906]
  • Feng Li, Zhengyan Zhang, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan Su. Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism. Molecules (Basel, Switzerland). 2023 Oct; 28(19):. doi: 10.3390/molecules28196918. [PMID: 37836761]
  • Yihao Liu, Zhen Qin, Chunling Wang, Zhengqiang Jiang. N-acetyl-d-glucosamine-based oligosaccharides from chitin: Enzymatic production, characterization and biological activities. Carbohydrate polymers. 2023 Sep; 315(?):121019. doi: 10.1016/j.carbpol.2023.121019. [PMID: 37230627]
  • Zeqi Li, Bo Fu, Aili Wei, Yanchen Wu, Ming Huang, Enhao Zhang, Bo Cui, Bo Wang, Hui Peng. d-Glucosamine induces circadian phase delay by promoting BMAL1 degradation through AMPK/mTOR pathway. Life sciences. 2023 Jul; 325(?):121765. doi: 10.1016/j.lfs.2023.121765. [PMID: 37169147]
  • Giorgia Della Rocca, Carlo Schievano, Alessandra Di Salvo, Maria Beatrice Conti, Maria Federica Della Valle. Palmitoyl-glucosamine co-micronized with curcumin for maintenance of meloxicam-induced pain relief in dogs with osteoarthritis pain. BMC veterinary research. 2023 Feb; 19(1):37. doi: 10.1186/s12917-023-03594-4. [PMID: 36747264]
  • Yingde Xu, Liangjie Sun, Xiaodan Gao, Jingkuan Wang. Contrasting response of fungal versus bacterial residue accumulation within soil aggregates to long-term fertilization. Scientific reports. 2022 10; 12(1):17834. doi: 10.1038/s41598-022-22064-9. [PMID: 36284223]
  • G Zhou, M W Zhao, Y P Cao, J H Lin, W G Wang, A Guo, H Tian. [A multicenter cross-sectional study of quality of life and nonsurgical treatment in patients with knee osteoarthritis]. Zhonghua yi xue za zhi. 2022 Sep; 102(35):2799-2805. doi: 10.3760/cma.j.cn112137-20220406-00719. [PMID: 36124353]
  • Ying Chen, Xiaoming Liao, Pei Jing, Liangkui Hu, Zengqiu Yang, Yongchao Yao, Chunyan Liao, Shiyong Zhang. Linoleic Acid-Glucosamine Hybrid for Endogenous Iron-Activated Ferroptosis Therapy in High-Grade Serous Ovarian Cancer. Molecular pharmaceutics. 2022 09; 19(9):3187-3198. doi: 10.1021/acs.molpharmaceut.2c00333. [PMID: 35939328]
  • Kun Gao, Yukun Qin, Linsong Wang, Xin Li, Song Liu, Ronge Xing, HuaHua Yu, Xiaolin Chen, Pengcheng Li. Design, Synthesis, and Antifungal Activities of Hymexazol Glycosides Based on a Biomimetic Strategy. Journal of agricultural and food chemistry. 2022 Aug; 70(30):9520-9535. doi: 10.1021/acs.jafc.2c02507. [PMID: 35877994]
  • Jing Chen, Li-Na Huo, Yuan Gao, Yun-Li Zhang, Ye Chen. Two new N-acetyl-ᴅ-glucosamine derivatives from the medical algae-derived endophytic fungus Penicillium chrysogenum. Natural product research. 2022 Aug; 36(15):3988-3991. doi: 10.1080/14786419.2021.1889543. [PMID: 33957817]
  • Venkanna Babu Mullapudi, Kendall C Craig, Zhongwu Guo. Design and Synthesis of a Doubly Functionalized Core Structure of a Glycosylphosphatidylinositol Anchor Containing Photoreactive and Clickable Functional Groups. The Journal of organic chemistry. 2022 07; 87(14):9419-9425. doi: 10.1021/acs.joc.2c00901. [PMID: 35766889]
  • Bojian Chen, Lei Fang, Liangzhuo Lin, Yang Lv, Zexin Huang, Xiaodong Lin, Xin Wang. Aerobic exercise combined with glucosamine hydrochloride capsules inhibited the apoptosis of chondrocytes in rabbit knee osteoarthritis by affecting TRPV5 expression. Gene. 2022 Jul; 830(?):146465. doi: 10.1016/j.gene.2022.146465. [PMID: 35427733]
  • Alexandre de Fátima Cobre, Monica Surek, Dile Pontarolo Stremel, Mariana Millan Fachi, Helena Hiemisch Lobo Borba, Fernanda Stumpf Tonin, Roberto Pontarolo. Diagnosis and prognosis of COVID-19 employing analysis of patients' plasma and serum via LC-MS and machine learning. Computers in biology and medicine. 2022 Jul; 146(?):105659. doi: 10.1016/j.compbiomed.2022.105659. [PMID: 35751188]
  • Janeala J Morsby, Bradley D Smith. Advances in Optical Sensors of N-Acetyl-β-d-hexosaminidase (N-Acetyl-β-d-glucosaminidase). Bioconjugate chemistry. 2022 04; 33(4):544-554. doi: 10.1021/acs.bioconjchem.2c00057. [PMID: 35302753]
  • Peipei Han, Yingying Wei, Shu Jiang, Yi Chen, Feng Xu, Hongfei Wang, Xingfeng Shao. N-Acetyl-d-glucosamine Inhibition of Hexokinase Results in Downregulation of the Phenylpropanoid Metabolic Pathway and Decreased Resistance to Brown Rot in Peach Fruit. Journal of agricultural and food chemistry. 2022 Mar; 70(12):3917-3928. doi: 10.1021/acs.jafc.1c06573. [PMID: 35298175]
  • Salim Cerig, Fatime Geyikoglu. Oxidative stress and cyto-genotoxicity induced by poly-d-glucosamine in human blood cells in vitro. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2022 Jan; 77(1-2):43-55. doi: 10.1515/znc-2021-0080. [PMID: 34036758]
  • Rebecca A Bova, Angela Melton-Celsa. Shiga toxin (Stx) type 2-induced increase in O-linked N-acetyl glucosamine protein modification: a new therapeutic target?. EMBO molecular medicine. 2022 01; 14(1):e15389. doi: 10.15252/emmm.202115389. [PMID: 34935281]
  • Sekhu Ansari, Dharmendra Nath Bhatt, Chandni Sood, Asis Datta. Functional characterization of the LdNAGD gene in Leishmania donovani. Microbiological research. 2021 Oct; 251(?):126830. doi: 10.1016/j.micres.2021.126830. [PMID: 34385082]
  • Congcong Zhang, Yongjie Niu, Zhixian Wang, Xin Xu, Yan Li, Lifang Ma, Jiayi Wang, Yongchun Yu. Corosolic acid inhibits cancer progression by decreasing the level of CDK19-mediated O-GlcNAcylation in liver cancer cells. Cell death & disease. 2021 09; 12(10):889. doi: 10.1038/s41419-021-04164-y. [PMID: 34588426]
  • Fabio A Facchini, Alberto Minotti, Andrea Luraghi, Alessio Romerio, Nicole Gotri, Alejandra Matamoros-Recio, Andrea Iannucci, Charys Palmer, Guanbo Wang, Rebecca Ingram, Sonsoles Martin-Santamaria, Grisha Pirianov, Marco De Andrea, Miguel A Valvano, Francesco Peri. Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity. Journal of medicinal chemistry. 2021 08; 64(16):12261-12272. doi: 10.1021/acs.jmedchem.1c00896. [PMID: 34382796]
  • Seyedeh Fatemeh Mirpoor, Odile Francesca Restaino, Chiara Schiraldi, Concetta Valeria L Giosafatto, Francesco Ruffo, Raffaele Porta. Lignin/Carbohydrate Complex Isolated from Posidonia oceanica Sea Balls (Egagropili): Characterization and Antioxidant Reinforcement of Protein-Based Films. International journal of molecular sciences. 2021 Aug; 22(17):. doi: 10.3390/ijms22179147. [PMID: 34502058]
  • Speranta Avram, Ana Maria Udrea, Diana Camelia Nuta, Carmen Limban, Adrian Cosmin Balea, Miron Teodor Caproiu, Florea Dumitrascu, Cătălin Buiu, Alexandra Teodora Bordei. Synthesis and Bioinformatic Characterization of New Schiff Bases with Possible Applicability in Brain Disorders. Molecules (Basel, Switzerland). 2021 Jul; 26(14):. doi: 10.3390/molecules26144160. [PMID: 34299440]
  • Jessica M Moon, Peter Finnegan, Richard A Stecker, Hanna Lee, Kayla M Ratliff, Ralf Jäger, Martin Purpura, Carolyn M Slupsky, Maria L Marco, Craig J Wissent, Jason Theodosakis, Chad M Kerksick. Impact of Glucosamine Supplementation on Gut Health. Nutrients. 2021 Jun; 13(7):. doi: 10.3390/nu13072180. [PMID: 34202877]
  • Lei Fang, Liangzhuo Lin, Yang Lv, Zexin Huang, Xiaodong Lin, Xin Wang, Bojian Chen. The mechanism of aerobic exercise combined with glucosamine therapy and circUNK in improving knee osteoarthritis in rabbits. Life sciences. 2021 Jun; 275(?):119375. doi: 10.1016/j.lfs.2021.119375. [PMID: 33737085]
  • William M Moore, Candace Chan, Toshiki Ishikawa, Emilie A Rennie, Heidi M-L Wipf, Veronica Benites, Maki Kawai-Yamada, Jenny C Mortimer, Henrik V Scheller. Reprogramming sphingolipid glycosylation is required for endosymbiont persistence in Medicago truncatula. Current biology : CB. 2021 06; 31(11):2374-2385.e4. doi: 10.1016/j.cub.2021.03.067. [PMID: 33857428]
  • Cornelio Barrientos, Angélica Pérez, Jorge Vázquez. Ameliorative Effects of Oral Glucosamine on Insulin Resistance and Pancreatic Tissue Damage in Experimental Wistar rats on a High-fat Diet. Comparative medicine. 2021 06; 71(3):215-221. doi: 10.30802/aalas-cm-21-000009. [PMID: 34082859]
  • Raushan Kumar, Komal Saraswat, Syed Ibrahim Rizvi. Glucosamine Displays a Potent Caloric Restriction Mimetic Effect in Senescent Rats by Activating Mitohormosis. Rejuvenation research. 2021 Jun; 24(3):220-226. doi: 10.1089/rej.2020.2399. [PMID: 33478352]
  • Jin Zhang, Ruiyi Ge, Ziquan Yang. Effect of celecoxib combined with glucosamine hydrochloride in promoting the functional recovery and decreasing the inflammatory factor levels in patients with knee osteoarthritis. Pakistan journal of pharmaceutical sciences. 2021 May; 34(3(Special)):1277-1282. doi: NULL. [PMID: 34602400]
  • Boon Hooi Tan, Nafees Ahemad, Yan Pan, Uma Devi Palanisamy, Iekhsan Othman, Chin Eng Ong. In vitro inhibitory effects of glucosamine, chondroitin and diacerein on human hepatic CYP2D6. Drug metabolism and personalized therapy. 2021 04; 36(4):259-270. doi: 10.1515/dmpt-2020-0182. [PMID: 34821124]
  • Chhavi Asthana, Gregory M Peterson, Madhur D Shastri, Rahul P Patel. Variation in the pharmacokinetics of glucosamine in healthy individuals. Rheumatology (Oxford, England). 2021 03; 60(3):1205-1209. doi: 10.1093/rheumatology/keaa418. [PMID: 32901283]
  • Mingxing Luo, Fangfang Xu, Qingze Wang, Wenli Luo. The inhibiting effect of glucosamine sulfate combined with loxoprofen sodium on chondrocyte apoptosis in rats with knee osteoarthritis. Journal of musculoskeletal & neuronal interactions. 2021 03; 21(1):113-120. doi: NULL. [PMID: 33657761]
  • Waliul Islam, Yoshitaka Matsumoto, Jun Fang, Ayaka Harada, Takuro Niidome, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takahisa Imamura, Kazuo Sakurai, Nobuyoshi Fukumitsu, Hirofumi Yamamoto, Hiroshi Maeda. Polymer-conjugated glucosamine complexed with boric acid shows tumor-selective accumulation and simultaneous inhibition of glycolysis. Biomaterials. 2021 02; 269(?):120631. doi: 10.1016/j.biomaterials.2020.120631. [PMID: 33450582]
  • Julian E A Leakey, A Afshan Ali, Amy R Babb, Heidi L Badgley, Kelly J Davis, Beth E Juliar, Tatiana I Leakey, Sherry M Lewis, Ralph E Patton, John E Seng. Subchronic toxicity evaluation of glucosamine and glucosamine in combination with chondroitin sulfate in obese Zucker rats. Toxicology and applied pharmacology. 2021 02; 412(?):115371. doi: 10.1016/j.taap.2020.115371. [PMID: 33345901]
  • Yi Chen, Wenquan Hu, Qi Li, Shiwei Zhao, Dan Zhao, Shuang Zhang, Zhuo Wei, Xiaoxiao Yang, Yuanli Chen, Xiaoju Li, Chenzhong Liao, Jihong Han, Qing Robert Miao, Yajun Duan. NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. The Journal of biological chemistry. 2021 Jan; 296(?):100624. doi: 10.1016/j.jbc.2021.100624. [PMID: 33812996]
  • Chiara Caterino, Federica Aragosa, Giovanni Della Valle, Dario Costanza, Francesco Lamagna, Alfonso Piscitelli, Annalisa Nieddu, Gerardo Fatone. Clinical efficacy of Curcuvet and Boswellic acid combined with conventional nutraceutical product: An aid to canine osteoarthritis. PloS one. 2021; 16(5):e0252279. doi: 10.1371/journal.pone.0252279. [PMID: 34048452]
  • Jingsheng Liu, Xiaoli Dong, Yining Liu, Kai Wang, Shuanhu Lei, Mingxuan Yang, Haiyuan Yue, Haijun Feng, Kai Feng, Kang Li, Jianwei Zhou, Yanqiang Chen, Wenjia Du, Xuewen Kang, Yayi Xia. The Identified Hub Gene GlcN in Osteoarthritis Progression and Treatment. Computational and mathematical methods in medicine. 2021; 2021(?):5499450. doi: 10.1155/2021/5499450. [PMID: 34754325]
  • Zbigniew Żęgota, Joanna Goździk, Joanna Głogowska-Szeląg. EFFICACY OF HERBAL AND NATURALLY-DERIVED DIETARY SUPPLEMENTS FOR THE MANAGEMENT OF KNEE OSTEOARTHRITIS: A MINI-REVIEW. Wiadomosci lekarskie (Warsaw, Poland : 1960). 2021; 74(8):1975-1983. doi: . [PMID: 34537753]
  • Anna Starzyńska-Janiszewska, Robert Duliński, Bożena Stodolak. Fermentation with Edible Rhizopus Strains to Enhance the Bioactive Potential of Hull-Less Pumpkin Oil Cake. Molecules (Basel, Switzerland). 2020 Dec; 25(24):. doi: 10.3390/molecules25245782. [PMID: 33302391]
  • Rianne A G Harmsen, Berit Bjugan Aam, Jogi Madhuprakash, Anne Grethe Hamre, Ethan D Goddard-Borger, Stephen G Withers, Vincent G H Eijsink, Morten Sørlie. Chemoenzymatic Synthesis of Chito-oligosaccharides with Alternating N-d-Acetylglucosamine and d-Glucosamine. Biochemistry. 2020 12; 59(48):4581-4590. doi: 10.1021/acs.biochem.0c00839. [PMID: 33213137]
  • Ping Lin, Jia-Cheng Zeng, Ji-Guang Chen, Xu-Liang Nie, En Yuan, Xiao-Qiang Wang, Da-Yong Peng, Zhong-Ping Yin. Synthesis, in vitro inhibitory activity, kinetic study and molecular docking of novel N-alkyl-deoxynojirimycin derivatives as potential α-glucosidase inhibitors. Journal of enzyme inhibition and medicinal chemistry. 2020 Dec; 35(1):1879-1890. doi: 10.1080/14756366.2020.1826941. [PMID: 33003963]
  • Yoshihiro Seto, Takuya Yoshihashi, Mari Tomonari, Hideto To. Absorption of glucosamine is improved by considering circadian rhythm and feeding time in rats. Chronobiology international. 2020 11; 37(11):1528-1537. doi: 10.1080/07420528.2020.1784189. [PMID: 32576047]
  • Niels R M Reintjens, Elena Tondini, Ana R de Jong, Nico J Meeuwenoord, Fabrizio Chiodo, Evert Peterse, Herman S Overkleeft, Dmitri V Filippov, Gijsbert A van der Marel, Ferry Ossendorp, Jeroen D C Codée. Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides. Journal of medicinal chemistry. 2020 10; 63(20):11691-11706. doi: 10.1021/acs.jmedchem.0c00851. [PMID: 32960056]
  • Aman Khanna, Sivadasan Syam Das, Thozhuthum Parambil Smina, Jestin V Thomas, Ajaikumar B Kunnumakkara, Balu Maliakel, Illathu Madhavamenon Krishnakumar, Ratheesh Mohanan. Curcumagalactomannoside/Glucosamine Combination Improved Joint Health Among Osteoarthritic Subjects as Compared to Chondroitin Sulfate/Glucosamine: Double-Blinded, Randomized Controlled Study. Journal of alternative and complementary medicine (New York, N.Y.). 2020 Oct; 26(10):945-955. doi: 10.1089/acm.2020.0128. [PMID: 32678677]
  • Jiwon Park, Yunkyoung Lee, Eun-Hye Jung, Sang-Min Kim, Hyeongjin Cho, Inn-Oc Han. Glucosamine regulates hepatic lipid accumulation by sensing glucose levels or feeding states of normal and excess. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2020 10; 1865(10):158764. doi: 10.1016/j.bbalip.2020.158764. [PMID: 32663610]
  • Hardik Naik Jinal, Natrajan Amaresan. In Silico and In Vitro Analyses of Glucosamine and Indole Acetaldehyde Inhibit Pathogenic Regulator Gene phcA of Ralstonia solanacearum, a Causative Agent of Bacterial Wilt of Tomato. Applied biochemistry and biotechnology. 2020 Sep; 192(1):230-242. doi: 10.1007/s12010-020-03328-4. [PMID: 32367442]
  • Atanasio Pandiella-Alonso, Elena Díaz-Rodríguez, Eduardo Sanz. Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review. Nutrients. 2020 Aug; 12(9):. doi: 10.3390/nu12092661. [PMID: 32878230]
  • Chhavi Asthana, Gregory M Peterson, Madhur D Shastri, Graeme Jones, Rahul P Patel. Variation in Plasma Levels of Glucosamine With Chronic Dosing: A Possible Reason for Inconsistent Clinical Outcomes in Osteoarthritis. Clinical therapeutics. 2020 08; 42(8):e140-e149. doi: 10.1016/j.clinthera.2020.06.009. [PMID: 32713600]
  • Nazafarin Satari, Somayeh Taymouri, Jaleh Varshosaz, Mahboubeh Rostami, Mina Mirian. Preparation and evaluation of inhalable dry powder containing glucosamine-conjugated gefitinib SLNs for lung cancer therapy. Drug development and industrial pharmacy. 2020 Aug; 46(8):1265-1277. doi: 10.1080/03639045.2020.1788063. [PMID: 32594775]
  • S M Heffernan, C McCarthy, S Eustace, R E FitzPatrick, E Delahunt, G De Vito. Mineral rich algae with pine bark improved pain, physical function and analgesic use in mild-knee joint osteoarthritis, compared to Glucosamine: A randomized controlled pilot trial. Complementary therapies in medicine. 2020 May; 50(?):102349. doi: 10.1016/j.ctim.2020.102349. [PMID: 32444040]
  • Yong Sun, Changde Wang, Chunzhu Gong. Repairing effects of glucosamine sulfate in combination with etoricoxib on articular cartilages of patients with knee osteoarthritis. Journal of orthopaedic surgery and research. 2020 Apr; 15(1):150. doi: 10.1186/s13018-020-01648-z. [PMID: 32299482]
  • Yu Fu, Jing Liu, Wei Zhang, Sandra S Wæhrens, Marie Tøstesen, Erik T Hansen, Wender L P Bredie, René Lametsch. Exopeptidase treatment combined with Maillard reaction modification of protein hydrolysates derived from porcine muscle and plasma: Structure-taste relationship. Food chemistry. 2020 Feb; 306(?):125613. doi: 10.1016/j.foodchem.2019.125613. [PMID: 31610331]
  • Mark W Grzanna, Rebecca Y Au, Angela Y Au, Ann M Rashmir, Carmelita G Frondoza. Avocado/Soybean Unsaponifiables, Glucosamine and Chondroitin Sulfate Combination Inhibits Proinflammatory COX-2 Expression and Prostaglandin E2 Production in Tendon-Derived Cells. Journal of medicinal food. 2020 Feb; 23(2):139-146. doi: 10.1089/jmf.2019.0022. [PMID: 31486703]
  • Chhavi Asthana, Gregory M Peterson, Madhur D Shastri, Rahul P Patel. A novel and sensitive HILIC-CAD method for glucosamine quantification in plasma and its application to a human pharmacokinetic study. Journal of pharmaceutical and biomedical analysis. 2020 Jan; 178(?):112954. doi: 10.1016/j.jpba.2019.112954. [PMID: 31704130]
  • Sven Basa, Malathi Nampally, Talita Honorato, Subha N Das, Appa R Podile, Nour E El Gueddari, Bruno M Moerschbacher. The Pattern of Acetylation Defines the Priming Activity of Chitosan Tetramers. Journal of the American Chemical Society. 2020 01; 142(4):1975-1986. doi: 10.1021/jacs.9b11466. [PMID: 31895979]
  • Weiwei Wang, Junting Fan, Guang Zhu, Jing Wang, Yumei Qian, Hongxia Li, Jianming Ju, Lingling Shan. Targeted Prodrug-Based Self-Assembled Nanoparticles for Cancer Therapy. International journal of nanomedicine. 2020; 15(?):2921-2933. doi: 10.2147/ijn.s247443. [PMID: 32425524]
  • Sandi L Navarro, Marta Herrero, Helena Martinez, Yuzheng Zhang, Jon Ladd, Edward Lo, David Shelley, Timothy W Randolph, Johanna W Lampe, Paul D Lampe. Differences in Serum Biomarkers Between Combined Glucosamine and Chondroitin Versus Celecoxib in a Randomized, Double-blind Trial in Osteoarthritis Patients. Anti-inflammatory & anti-allergy agents in medicinal chemistry. 2020; 19(2):190-201. doi: 10.2174/1871523018666190115094512. [PMID: 30648524]
  • Marika Cordaro, Rosalba Siracusa, Daniela Impellizzeri, Ramona D' Amico, Alessio Filippo Peritore, Rosalia Crupi, Enrico Gugliandolo, Roberta Fusco, Rosanna Di Paola, Carlo Schievano, Salvatore Cuzzocrea. Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain. Arthritis research & therapy. 2019 11; 21(1):254. doi: 10.1186/s13075-019-2048-y. [PMID: 31779692]
  • Antonietta Stellavato, Odile Francesca Restaino, Valentina Vassallo, Rosario Finamore, Carlo Ruosi, Elisabetta Cassese, Mario De Rosa, Chiara Schiraldi. Comparative Analyses of Pharmaceuticals or Food Supplements Containing Chondroitin Sulfate: Are Their Bioactivities Equivalent?. Advances in therapy. 2019 11; 36(11):3221-3237. doi: 10.1007/s12325-019-01064-8. [PMID: 31494830]
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