Arborinine (BioDeep_00000412402)

Main id: BioDeep_00000008224

 

natural product


代谢物信息卡片


Arborinine

化学式: C16H15NO4 (285.100103)
中文名称: 山小柑碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C2=CC=CC=C2C(=O)C3=C(C(=C(C=C31)OC)OC)O
InChI: InChI=1S/C16H15NO4/c1-17-10-7-5-4-6-9(10)14(18)13-11(17)8-12(20-2)16(21-3)15(13)19/h4-8,19H,1-3H3

描述信息

同义名列表

2 个代谢物同义名

Arborinine; Arborinine



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

89 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Laina Zarisa Mohd Kamal, Mowaffaq Adam Ahmed Adam, Siti Nurfatimah Mohd Shahpudin, Ahmad Naqeeb Shuib, Rosline Sandai, Norazian Mohd Hassan, Yasser Tabana, Dayang Fredalina Basri, Leslie Thian Lung Than, Doblin Sandai. Identification of Alkaloid Compounds Arborinine and Graveoline from Ruta angustifolia (L.) Pers for their Antifungal Potential against Isocitrate lyase (ICL1) gene of Candida albicans. Mycopathologia. 2021 May; 186(2):221-236. doi: 10.1007/s11046-020-00523-z. [PMID: 33550536]
  • Kitiya Piboonprai, Phattharachanok Khumkhrong, Mattaka Khongkow, Teerapong Yata, Nijsiri Ruangrungsi, Chaisak Chansriniyom, Tawin Iempridee. Anticancer activity of arborinine from Glycosmis parva leaf extract in human cervical cancer cells. Biochemical and biophysical research communications. 2018 06; 500(4):866-872. doi: 10.1016/j.bbrc.2018.04.175. [PMID: 29705700]
  • Victor Kuete, Louis P Sandjo, Jackson A Seukep, Maen Zeino, Armelle T Mbaveng, Bonaventure Ngadjui, Thomas Efferth. Cytotoxic compounds from the fruits of Uapaca togoensis towards multifactorial drug-resistant cancer cells. Planta medica. 2015 Jan; 81(1):32-8. doi: 10.1055/s-0034-1383362. [PMID: 25473921]
  • Hugues Fouotsa, Armelle T Mbaveng, Celine D Mbazoa, Augustin E Nkengfack, Shaheen Farzana, Choudhary M Iqbal, Jacobus J Marion Meyer, Namrita Lall, Victor Kuete. Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis. BMC complementary and alternative medicine. 2013 Apr; 13(?):81. doi: 10.1186/1472-6882-13-81. [PMID: 23574627]
  • Rostand M Ngoumfo, Jean-Bosco Jouda, Ferdinand T Mouafo, Justin Komguem, Céline D Mbazoa, Tze Chieh Shiao, Mohammed I Choudhary, Hartmut Laatsch, Jean Legault, André Pichette, René Roy. In vitro cytotoxic activity of isolated acridones alkaloids from Zanthoxylum leprieurii Guill. et Perr. Bioorganic & medicinal chemistry. 2010 May; 18(10):3601-5. doi: 10.1016/j.bmc.2010.03.040. [PMID: 20413315]
  • Renata Roseghini, Georgenes Morato Falcão, José Fernando Oliveira Costa, Jorge Clarêncio, Ivana Nascimento, Eudes Velozo, Robert Schaer, Vera Vale, Silvia Lima Costa, Maria de Fátima Dias Costa, Marcienne Tardy, Roberto Meyer, Songelí Menezes Freire. The flavonoid rutin but not the alkaloid arborinine induces apoptosis in a B-cell hybridoma cell line. Planta medica. 2009 Apr; 75(5):488-93. doi: 10.1055/s-0029-1185316. [PMID: 19235127]
  • Judith M Rollinger, Daniela Schuster, Birgit Danzl, Stefan Schwaiger, Patrick Markt, Michaela Schmidtke, Jürg Gertsch, Stefan Raduner, Gerhard Wolber, Thierry Langer, Hermann Stuppner. In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens. Planta medica. 2009 Feb; 75(3):195-204. doi: 10.1055/s-0028-1088397. [PMID: 19096995]
  • Borbála Réthy, István Zupkó, Renáta Minorics, Judit Hohmann, Imre Ocsovszki, George Falkay. Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens. Planta medica. 2007 Jan; 73(1):41-8. doi: 10.1055/s-2006-951747. [PMID: 17109253]
  • Chihiro Ito, Masataka Itoigawa, Atsuko Sato, Choudhury M Hasan, Mohammad A Rashid, Harukuni Tokuda, Teruo Mukainaka, Hoyoku Nishino, Hiroshi Furukawa. Chemical constituents of Glycosmis arborea: three new carbazole alkaloids and their biological activity. Journal of natural products. 2004 Sep; 67(9):1488-91. doi: 10.1021/np0400611. [PMID: 15387647]
  • Mary W Muriithi, W-R Abraham, Jonathan Addae-Kyereme, Ian Scowen, Simon L Croft, Peter M Gitu, Howard Kendrick, E N M Njagi, Colin W Wright. Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine. Journal of natural products. 2002 Jul; 65(7):956-9. doi: 10.1021/np0106182. [PMID: 12141852]
  • C Tringali, C Spatafora, V Calì, M S Simmonds. Antifeedant constituents from Fagara macrophylla. Fitoterapia. 2001 Jun; 72(5):538-43. doi: 10.1016/s0367-326x(01)00265-9. [PMID: 11429249]
  • X D Ji, N Melman, K A Jacobson. Interactions of flavonoids and other phytochemicals with adenosine receptors. Journal of medicinal chemistry. 1996 Feb; 39(3):781-8. doi: 10.1021/jm950661k. [PMID: 8576921]