NCBI Taxonomy: 2588167

Zanthoxylum rubescens (ncbi_taxid: 2588167)

found 43 associated metabolites at species taxonomy rank level.

Ancestor: Zanthoxylum

Child Taxonomies: none taxonomy data.

Vanillic acid

4-hydroxy-3-methoxybenzoic acid

C8H8O4 (168.0423)


Vanillic acid is a phenolic acid found in some forms of vanilla and many other plant extracts. It is a flavouring and scent agent that produces a pleasant, creamy odour. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin (J Biotechnol 1996;50(2-3):107-13). Vanillic acid, which is a chlorogenic acid, is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid is a metabolic byproduct of caffeic acid and is often found in the urine of humans who have consumed coffee, chocolate, tea, and vanilla-flavoured confectionary. Vanillic acid selectively and specifically inhibits 5nucleotidase activity (PMID: 16899266). Vanillic acid is a microbial metabolite found in Amycolatopsis, Delftia, and Pseudomonas (PMID: 11152072, 10543794, 11728709, 9579070). Vanillic acid is a phenolic acid found in some forms of vanilla and many other plant extracts. It is a flavoring and scent agent that produces a pleasant, creamy odor. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). Vanillic acid, which is a chlorogenic acid, is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid is a metabolic byproduct of caffeic acid and is often found in the urine of humans who have consumed coffee, chocolate, tea and vanilla-flavored confectionary. Vanillic acid selectively and specifically inhibits 5nucleotidase activity. (PMID: 16899266). Vanillic acid is a monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. It has a role as a plant metabolite. It is a monohydroxybenzoic acid and a methoxybenzoic acid. It is a conjugate acid of a vanillate. Vanillic acid is a natural product found in Ficus septica, Haplophyllum cappadocicum, and other organisms with data available. Vanillic acid is a metabolite found in or produced by Saccharomyces cerevisiae. A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. Vanillic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=121-34-6 (retrieved 2024-06-29) (CAS RN: 121-34-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1].

   

Lupeol

(1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol

C30H50O (426.3861)


Lupeol is a pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables. It has a role as an anti-inflammatory drug and a plant metabolite. It is a secondary alcohol and a pentacyclic triterpenoid. It derives from a hydride of a lupane. Lupeol has been investigated for the treatment of Acne. Lupeol is a natural product found in Ficus auriculata, Ficus septica, and other organisms with data available. See also: Calendula Officinalis Flower (part of). A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables. D000893 - Anti-Inflammatory Agents Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1]. Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1].

   

Nitidine

Nitidine chloride

C21H18NO4+ (348.1236)


   

Chelerythrine

17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13),2,4(8),9,11,14(19),15,17,20-nonaen-21-ium

C21H18NO4+ (348.1236)


Chelerythrine is a benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae. It has a role as an EC 2.7.11.13 (protein kinase C) inhibitor, an antibacterial agent and an antineoplastic agent. It is a benzophenanthridine alkaloid and an organic cation. A benzophenanthridine alkaloid evaluated as a kinase-inhibitor. Chelerythrine is a natural product found in Zanthoxylum fagara, Zanthoxylum mayu, and other organisms with data available. Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable protein kinase C inhibitor. See also: Sanguinaria canadensis root (part of); Chelidonium majus flowering top (part of). A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae. D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D000970 - Antineoplastic Agents

   

Fagaramide

3-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)prop-2-enamide

C14H17NO3 (247.1208)


   

Arborinine

9(10H)-Acridinone, 1-hydroxy-2,3-dimethoxy-10-methyl- (9ci)

C16H15NO4 (285.1001)


Arborinine is found in herbs and spices. Arborinine is an alkaloid from Ruta graveolens (rue

   

gamma-Fagarine

4,8-Dimethoxyfuro[2,3-b]quinoline; 8-Methoxydictamnine; Fagarine

C13H11NO3 (229.0739)


Gamma-Fagarine is an organic heterotricyclic compound, an organonitrogen heterocyclic compound and an oxacycle. gamma-Fagarine is a natural product found in Haplophyllum bucharicum, Haplophyllum griffithianum, and other organisms with data available. gamma-Fagarine is found in fruits. gamma-Fagarine is an alkaloid from Aegle marmelos (bael fruit

   

N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,4-dimethoxycinnamic acid amide

(2E)-3-(3,4-Dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidate

C21H25NO5 (371.1733)


N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,4-dimethoxycinnamic acid amide is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]")

   

1-Hydroxy-3-methoxy-10-methylacridone

1-hydroxy-3-methoxy-10-methyl-9,10-dihydroacridin-9-one

C15H13NO3 (255.0895)


1-Hydroxy-3-methoxy-10-methylacridone is found in herbs and spices. 1-Hydroxy-3-methoxy-10-methylacridone is an alkaloid from the roots Ruta graveolens (rue

   

6-Methoxydihydrochelerythrine

6-Methoxydihydrochelerythrine

C22H21NO5 (379.142)


   

lupeol

Lup-20(29)-en-3.beta.-ol

C30H50O (426.3861)


D000893 - Anti-Inflammatory Agents Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1]. Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1].

   

Vanillic Acid

Vanillic acid hexoside

C8H8O4 (168.0423)


Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1].

   
   

Chelerythrine

Chelerythrine

C21H18NO4 (348.1236)


   

Chelerythrine

Chelerythrine

[C21H18NO4]+ (348.1236)


Annotation level-1

   

Arborinine

1-hydroxy-2,3-dimethoxy-10-methylacridin-9-one

C16H15NO4 (285.1001)


   

1-Hydroxy-3-methoxy-N-methylacridone

1-hydroxy-3-methoxy-10-methyl-9,10-dihydroacridin-9-one

C15H13NO3 (255.0895)


   

Rubemamine

(2E)-3-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide

C21H25NO5 (371.1733)


   

γ-Fagarine

gamma-Fagarine

C13H11NO3 (229.0739)


   

Vanillate

4-Hydroxy-3-methoxybenzoic acid

C8H8O4 (168.0423)


Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1].

   

toddaline

Chelerythrine

C21H18NO4+ (348.1236)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D000970 - Antineoplastic Agents

   

Fagarine

4-27-00-02211 (Beilstein Handbook Reference)

C13H11NO3 (229.0739)


   

1-Hydroxy-3-methoxy-10-methylacridone

1-Hydroxy-3-methoxy-10-methylacridone

C15H13NO3 (255.0895)


   

(2e)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methyl-3-phenylprop-2-enamide

(2e)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methyl-3-phenylprop-2-enamide

C19H19NO3 (309.1365)


   

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidic acid

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidic acid

C20H21NO5 (355.142)


   

(2e)-3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

(2e)-3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

C22H27NO5 (385.1889)


   

n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]cyclopropanecarboximidic acid

n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]cyclopropanecarboximidic acid

C13H15NO3 (233.1052)


   

3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidic acid

3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidic acid

C21H25NO5 (371.1733)


   

11,17,18-trimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,4(8),9,11,14,16,18-octaene

11,17,18-trimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,4(8),9,11,14,16,18-octaene

C22H21NO5 (379.142)


   

(2e)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-3-phenylprop-2-enimidic acid

(2e)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-3-phenylprop-2-enimidic acid

C18H17NO3 (295.1208)


   

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methylprop-2-enamide

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methylprop-2-enamide

C20H19NO5 (353.1263)


   

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-(2-methylpropyl)prop-2-enimidic acid

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-(2-methylpropyl)prop-2-enimidic acid

C14H17NO3 (247.1208)


   

(2z)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methyl-3-phenylprop-2-enamide

(2z)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methyl-3-phenylprop-2-enamide

C20H23NO3 (325.1678)


   

n-[6-(2-hydroxy-3,4-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

n-[6-(2-hydroxy-3,4-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

C21H19NO6 (381.1212)


   

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

C21H23NO5 (369.1576)


   

(2e)-3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidic acid

(2e)-3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enimidic acid

C21H25NO5 (371.1733)


   

(2e)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enimidic acid

(2e)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enimidic acid

C20H21NO5 (355.142)


   

3-(2h-1,3-benzodioxol-5-yl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

3-(2h-1,3-benzodioxol-5-yl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

C21H23NO5 (369.1576)


   

3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

3-(3,4-dimethoxyphenyl)-n-[2-(3,4-dimethoxyphenyl)ethyl]-n-methylprop-2-enamide

C22H27NO5 (385.1889)


   

3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]prop-2-enimidic acid

3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]prop-2-enimidic acid

C19H17NO5 (339.1107)


   

3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methylprop-2-enamide

3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methylprop-2-enamide

C20H19NO5 (353.1263)


   

n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methyl-3-phenylprop-2-enamide

n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-n-methyl-3-phenylprop-2-enamide

C19H19NO3 (309.1365)


   

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]prop-2-enimidic acid

(2e)-3-(2h-1,3-benzodioxol-5-yl)-n-[2-(2h-1,3-benzodioxol-5-yl)ethyl]prop-2-enimidic acid

C19H17NO5 (339.1107)