iproniazid (BioDeep_00000408936)
Main id: BioDeep_00000002008
代谢物信息卡片
N-propan-2-ylpyridine-4-carbohydrazide
化学式: C9H13N3O (179.1059)
中文名称: 异丙烟肼
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)NNC(=O)c(c1)ccnc1
InChI: InChI=1S/C9H13N3O/c1-7(2)11-12-9(13)8-3-5-10-6-4-8/h3-7,11H,1-2H3,(H,12,13)
描述信息
N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AF - Monoamine oxidase inhibitors, non-selective
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors
C471 - Enzyme Inhibitor > C667 - Monoamine Oxidase Inhibitor
同义名列表
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:5958
- KEGGdrug: D02579
- PubChem: 3748
- DrugBank: DB04818
- ChEMBL: CHEMBL92401
- MeSH: Iproniazid
- CAS: 54-92-2
- MoNA: WA002235
- MoNA: WA002234
- MoNA: WA002233
- MoNA: WA002232
- MoNA: WA002231
- MoNA: WA002230
- RefMet: Iproniazid
- KEGG: C11777
- PubChem: 13941
- KNApSAcK: 5958
分类词条
相关代谢途径
Reactome(0)
BioCyc(2)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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10.1016/0028-3908(71)90020-7. [PMID: 5126692] - L C Wong, P Millburn, R T Williams. The metabolism or (35S)homosulphanilamide.
The Biochemical journal.
1971 Sep; 124(2):17P. doi:
10.1042/bj1240017pa. [PMID: 5158478] - R B Rucker, B L O'Dell. Connective tissue amine oxidase. I. Purification of bovine aorta amine oxidase and its comparison with plasma amine oxidase.
Biochimica et biophysica acta.
1971 Apr; 235(1):32-43. doi:
10.1016/0005-2744(71)90030-1. [PMID: 5519136] - B Peskar, G Hellmann, G Hertting. Demonstration of 3,4-dihydroxy(14C)benzoic acid and (14C)vanillic acid after administration of (14C)noradrenaline in the rat.
The Journal of pharmacy and pharmacology.
1971 Apr; 23(4):270-5. doi:
10.1111/j.2042-7158.1971.tb08656.x. [PMID: 4396904] - B G Zimmerman, J C Liao, J Gisslen. Effect of phenoxybenzamine and combined administration of iproniazid and tropolone on catecholamine release elicited by renal sympathetic nerve stimulation.
The Journal of pharmacology and experimental therapeutics.
1971 Mar; 176(3):603-10. doi:
. [PMID: 5111453] - B Holstein. Metabolism of intraperitoneally injected 14 C-histamine in the yellow eel (Anguilla anguilla).
Comparative biochemistry and physiology. A, Comparative physiology.
1971 Feb; 38(2):435-41. doi:
10.1016/0300-9629(71)90066-1. [PMID: 4397612] - L V Devoino, L S Yeliseyeva. Influence of some drugs on the immune response. 3. Effect of serotonin, 5-hydroxytryptophan, reserpine, monoamine oxidase inhibitors, and DOPA on the involvement of lymph node cells in the immune response.
European journal of pharmacology.
1971; 14(1):71-6. doi:
10.1016/0014-2999(71)90124-5. [PMID: 5313885] - M J Mercier, A S Curry. [Enzymatic method for the detection of monoamine oxidase inhibitors].
European journal of toxicology.
1971 Jan; 4(1):36-8. doi:
NULL. [PMID: 5092664] - H Nagasawa, J Meites. Suppression by ergocornine and iproniazid of carcinogen-induced mammary tumors in rats; effects on serum and pituitary prolactin levels.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1970 Nov; 135(2):469-72. doi:
10.3181/00379727-135-35076. [PMID: 5480010] - M K Menon, A Kar, C S Chauhan. Some psychopharmacological actions of the essential oil of Litsea glutinosa (Lour.) C.B. Robins.
Indian journal of physiology and pharmacology.
1970 Jul; 14(3):185-92. doi:
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Biochemical pharmacology.
1970 Jun; 19(6):1929-42. doi:
10.1016/0006-2952(70)90289-3. [PMID: 5513969] - E Van Winkle, J W Schweitzer, A J Friedhoff. Beta-hydroxylation of N-acetyl-3,4-dimethoxyphenethylamine and the influence of iproniazid on the demethylation of this compound in vivo in the rat.
Biochemical pharmacology.
1970 Jun; 19(6):2137-44. doi:
10.1016/0006-2952(70)90313-8. [PMID: 5513979] - E M Kuchuk, B M Kopytin. [Effect of iprazid on the indices of lipid metabolism in healthy rabbits and rabbits with experimental atherosclerosis in lowlands and in mountainous areas].
Biulleten' eksperimental'noi biologii i meditsiny.
1970 Mar; 69(3):76-8. doi:
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Ukrains'kyi biokhimichnyi zhurnal.
1970; 42(6):770-4. doi:
NULL. [PMID: 5513591] - G B Nadkarni, K G Raghavan. Effect of iproniazid on excretion of aromatic amines in x-irradiated rats.
International journal of radiation biology and related studies in physics, chemistry, and medicine.
1970; 18(1):95-8. doi:
10.1080/09553007014550871. [PMID: 5311618] - D S Ingram. Abnormal growth of tissues infected with Plasmodiophora brassicae.
Journal of general microbiology.
1969 Apr; 56(1):55-67. doi:
10.1099/00221287-56-1-55. [PMID: 5787004] - L Buchel, L Liblau, M Murawsky, M Prioux-Guyonneau. [Influence of pyschotropic substances on variations of total plasma free fatty acids in constrained rats].
Archives des sciences physiologiques.
1969; 23(3):407-14. doi:
NULL. [PMID: 5808000] - L V Devoino, L S Korovina, R Y Ilyutchenok. Influence of some drugs on the immune response. I. The effect of 5-hydroxytryptophan, iproniazid and reserpine on primary and secondary immune responses.
European journal of pharmacology.
1968 Nov; 4(4):441-8. doi:
10.1016/0014-2999(68)90032-0. [PMID: 5303618] - K Voith, B A Kovacs. Hypnotic and hypothermic effect of pregnant mare urine extracts in the rat.
European journal of pharmacology.
1968 Oct; 4(3):270-82. doi:
10.1016/0014-2999(68)90094-0. [PMID: 5723422] - B P Kushelevskiĭ, A N Kokosov. [Some problems of the differentiated pathogenic therapy of angina pectoris of varied origin].
Kardiologiia.
1968 Jul; 8(7):46-50. doi:
NULL. [PMID: 4386948] - W H Vogel. Physiological disposition and metabolism of 3,4-dimethoxyphenylethylamine in the rat.
International journal of neuropharmacology.
1968 Jul; 7(4):373-81. doi:
10.1016/0028-3908(68)90020-8. [PMID: 4976276] - J V Burba. Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
Canadian journal of biochemistry.
1968 Apr; 46(4):367-71. doi:
10.1139/o68-054. [PMID: 5661678] - D S Robinson, W Lovenberg, H Keiser, A Sjoerdsma. Effects of drugs on human blood platelet and plasma amine oxidase activity in vitro and in vivo.
Biochemical pharmacology.
1968 Jan; 17(1):109-19. doi:
10.1016/0006-2952(68)90163-9. [PMID: 4384242] - J Price, G Hopkinson. Mono-amine oxidase inhibitors and schizophrenia.
Psychiatria clinica.
1968; 1(2):65-84. doi:
10.1159/000278517. [PMID: 4878603] - H Göschke. [Physiopathology and drug-modification of the carcinoid syndrome].
Schweizerische medizinische Wochenschrift.
1967 Nov; 97(46):1548-50. doi:
NULL. [PMID: 4875895] - N S Shah, S P Martin. Further studies with isocitric dehydrogenase in experimental tuberculosis: influence of isoniazid on metabolic damage.
The American review of respiratory disease.
1967 Jun; 95(6):1026-35. doi:
10.1164/arrd.1967.95.6.1026. [PMID: 4381693] - J M Musacchio, M Goldstein. The metabolism of mescaline-14-C in rats.
Biochemical pharmacology.
1967 Jun; 16(6):963-70. doi:
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