Ethanolamine (BioDeep_00000403062)

Main id: BioDeep_00000003123

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


MONOETHANOLAMINE

化学式: C2H7NO (61.0528)
中文名称: 乙醇胺-15N, 酸性橙 86, 乙醇胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CO)N
InChI: InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2

描述信息

A member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.
C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist

同义名列表

6 个代谢物同义名

Ethanolamine; MONOETHANOLAMINE; 2-azanylethanol; Acid Orange 86; Ethanolamine; Ethanolamine



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(10)

BioCyc(2)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

40 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, CHKA, CNR1, CNR2, ETNK1, ITPR3, PCYT2, PISD, PLA2G12A, PMP2
Peripheral membrane protein 2 CYP1B1, PISD
Endosome membrane 1 TF
Endoplasmic reticulum membrane 7 CEPT1, CYP1B1, FAAH, HSP90B1, ITPR3, PCYT2, SELENOI
Nucleus 4 ALB, HSP90B1, PISD, PMP2
cytosol 7 ALB, CHKA, ETNK1, HSP90B1, PISD, PMP2, PRKCQ
dendrite 1 CNR2
centrosome 1 ALB
nucleoplasm 1 ITPR3
Cell membrane 2 CNR1, TNF
Cell projection, axon 1 CNR1
Multi-pass membrane protein 5 CEPT1, CNR1, FAAH, ITPR3, SELENOI
cell surface 2 TF, TNF
glutamatergic synapse 2 CNR1, FAAH
Golgi apparatus 4 ALB, CEPT1, PISD, SELENOI
Golgi membrane 1 INS
growth cone 1 CNR1
lysosomal membrane 1 EGF
mitochondrial inner membrane 1 PISD
neuronal cell body 2 ITPR3, TNF
postsynapse 1 FAAH
presynaptic membrane 1 CNR1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 CHKA
Presynapse 2 CNR1, FAAH
plasma membrane 7 CNR1, CNR2, EGF, ITPR3, PRKCQ, TF, TNF
Membrane 8 CEPT1, CYP1B1, EGF, ETNK1, FAAH, HSP90B1, ITPR3, SELENOI
apical plasma membrane 1 TF
axon 1 CNR1
brush border 1 ITPR3
extracellular exosome 5 ALB, EGF, HSP90B1, PMP2, TF
endoplasmic reticulum 5 ALB, CNR2, FAAH, HSP90B1, ITPR3
extracellular space 5 ALB, EGF, INS, TF, TNF
perinuclear region of cytoplasm 2 HSP90B1, TF
mitochondrion 2 CYP1B1, PISD
protein-containing complex 2 ALB, HSP90B1
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 2 CYP1B1, FAAH
Secreted 4 ALB, INS, PLA2G12A, TF
extracellular region 7 ALB, EGF, HSP90B1, INS, PLA2G12A, TF, TNF
Mitochondrion outer membrane 1 CNR1
Single-pass membrane protein 2 FAAH, PISD
mitochondrial outer membrane 1 CNR1
basal part of cell 1 TF
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
Nucleus membrane 1 CEPT1
nuclear membrane 1 CEPT1
external side of plasma membrane 1 TNF
actin cytoskeleton 1 CNR1
perikaryon 1 CNR2
cytoplasmic vesicle 1 TF
nucleolus 1 ITPR3
midbody 1 HSP90B1
Early endosome 1 TF
apical part of cell 1 ITPR3
clathrin-coated pit 1 TF
recycling endosome 2 TF, TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 TF
postsynaptic membrane 1 CNR2
Membrane raft 2 CNR1, TNF
Cytoplasm, cytoskeleton 1 FAAH
focal adhesion 1 HSP90B1
GABA-ergic synapse 1 CNR1
sarcoplasmic reticulum 1 ITPR3
collagen-containing extracellular matrix 1 HSP90B1
nuclear outer membrane 1 ITPR3
Late endosome 1 TF
receptor complex 1 ITPR3
ciliary basal body 1 ALB
phagocytic cup 1 TNF
cytoskeleton 1 FAAH
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, TF
organelle membrane 1 FAAH
Endomembrane system 1 FAAH
endosome lumen 1 INS
Lipid droplet 2 CHKA, PISD
Cell projection, dendrite 1 CNR2
Melanosome 1 HSP90B1
myelin sheath 1 PMP2
sperm plasma membrane 1 HSP90B1
basal plasma membrane 1 TF
secretory granule lumen 2 INS, TF
HFE-transferrin receptor complex 1 TF
secretory granule membrane 1 ITPR3
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, HSP90B1, INS, TF
platelet alpha granule lumen 2 ALB, EGF
endocytic vesicle 1 TF
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
clathrin-coated endocytic vesicle membrane 2 EGF, TF
Sarcoplasmic reticulum lumen 1 HSP90B1
platelet dense tubular network membrane 1 ITPR3
extrinsic component of cytoplasmic side of plasma membrane 1 CNR2
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
Intermembrane side 1 PISD
vesicle coat 1 TF
endocytic vesicle lumen 1 HSP90B1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
transport vesicle membrane 1 ITPR3
endoplasmic reticulum chaperone complex 1 HSP90B1
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
[Isoform 1]: Lipid droplet 1 CHKA
ciliary transition fiber 1 ALB
[Isoform 2]: Mitochondrion inner membrane 1 PISD
dense body 1 TF
[Isoform 1]: Mitochondrion inner membrane 1 PISD
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[Phosphatidylserine decarboxylase beta chain]: Mitochondrion inner membrane 1 PISD
[Phosphatidylserine decarboxylase alpha chain]: Mitochondrion inner membrane 1 PISD


文献列表

  • Yeeun Son, Timothy C Kenny, Artem Khan, Kıvanç Birsoy, Richard K Hite. Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature. 2024 May; 629(8012):710-716. doi: 10.1038/s41586-024-07374-4. [PMID: 38693265]
  • Petrus Hemström, Bronwen Jugg, Rachel Watkins, Sofia Jonasson, Linda Elfsmark, Stephen Rutter, Crister Åstot, Pernilla Lindén. Phospholipid chlorohydrins as chlorine exposure biomarkers in a large animal model. Toxicology letters. 2024 Jan; 391(?):32-38. doi: 10.1016/j.toxlet.2023.11.008. [PMID: 38048885]
  • Mélissa Simard, Andréa Tremblay, Sophie Morin, Geneviève Rioux, Nicolas Flamand, Roxane Pouliot. N-eicosapentaenoyl-ethanolamine decreases the proliferation of psoriatic keratinocytes in a reconstructed psoriatic skin model. Scientific reports. 2023 07; 13(1):12113. doi: 10.1038/s41598-023-39185-4. [PMID: 37495686]
  • Somrita Basu, Mattie C Pawlowic, Fong-Fu Hsu, Geoff Thomas, Kai Zhang. Ethanolaminephosphate cytidylyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major. PLoS pathogens. 2023 07; 19(7):e1011112. doi: 10.1371/journal.ppat.1011112. [PMID: 37506172]
  • Linda M Westermann, Ian D E A Lidbury, Chun-Yang Li, Ning Wang, Andrew R J Murphy, Maria Del Mar Aguilo Ferretjans, Mussa Quareshy, Muralidharan Shanmugan, Alberto Torcello-Requena, Eleonora Silvano, Yu-Zhong Zhang, Claudia A Blindauer, Yin Chen, David J Scanlan. Bacterial catabolism of membrane phospholipids links marine biogeochemical cycles. Science advances. 2023 04; 9(17):eadf5122. doi: 10.1126/sciadv.adf5122. [PMID: 37126561]
  • Monica Bari, Monica Feole, Marina Fava, Mauro Maccarrone. Radiometric Assay of FAAH Activity. Methods in molecular biology (Clifton, N.J.). 2023; 2576(?):241-247. doi: 10.1007/978-1-0716-2728-0_20. [PMID: 36152192]
  • Huancong Shi, Xiaofang Cheng, Jiacheng Peng, Hongliang Feng, Paitoon Tontiwachwuthikul, Jiawei Hu. The CO2 absorption and desorption analysis of tri-solvent MEA + EAE + AMP compared with MEA + BEA + AMP along with 'coordination effects' evaluation. Environmental science and pollution research international. 2022 Jun; 29(27):40686-40700. doi: 10.1007/s11356-022-18792-0. [PMID: 35083697]
  • Zahra Khoshbin, Javad Zamanian, Negin Davoodian, Noor Mohammad Danesh, Mohammad Ramezani, Mona Alibolandi, Khalil Abnous, Seyed Mohammad Taghdisi. A simple and ultrasensitive metal-organic framework-based aptasensor for fluorescence detection of ethanolamine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2022 Feb; 267(Pt 2):120488. doi: 10.1016/j.saa.2021.120488. [PMID: 34739893]
  • Emmanuel E Moutoussamy, Qaiser Waheed, Greta J Binford, Hanif M Khan, Shane M Moran, Anna R Eitel, Matthew H J Cordes, Nathalie Reuter. Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: Role of a conserved aromatic cage. PLoS computational biology. 2022 02; 18(2):e1009871. doi: 10.1371/journal.pcbi.1009871. [PMID: 35180220]
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  • Chakravarthy Garlapati, Shriya Joshi, Ravi Chakra Turaga, Manjari Mishra, Michelle D Reid, Shobhna Kapoor, Liana Artinian, Vincent Rehder, Ritu Aneja. Monoethanolamine-induced glucose deprivation promotes apoptosis through metabolic rewiring in prostate cancer. Theranostics. 2021; 11(18):9089-9106. doi: 10.7150/thno.62724. [PMID: 34522228]
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  • Yasuhiro Horibata, Hiromi Ando, Hiroyuki Sugimoto. Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids. Journal of lipid research. 2020 08; 61(8):1221-1231. doi: 10.1194/jlr.ra120000898. [PMID: 32576654]
  • Ying-Chen Lin, Galileo Estopare Araguirang, Anh H Ngo, Kui-Ting Lin, Artik Elisa Angkawijaya, Yuki Nakamura. The Four Arabidopsis Choline/Ethanolamine Kinase Isozymes Play Distinct Roles in Metabolism and Development. Plant physiology. 2020 05; 183(1):152-166. doi: 10.1104/pp.19.01399. [PMID: 32205454]
  • Roberta Cazzola, Mariangela Rondanelli. N-Oleoyl-Phosphatidyl-Ethanolamine and Epigallo Catechin-3-Gallate Mitigate Oxidative Stress in Overweight and Class I Obese People on a Low-Calorie Diet. Journal of medicinal food. 2020 Mar; 23(3):319-325. doi: 10.1089/jmf.2019.0145. [PMID: 31928490]
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