glycocyamine (BioDeep_00000400352)

Main id: BioDeep_00000001348

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


2-Guanidinoacetic acid

化学式: C3H7N3O2 (117.0538)
中文名称: 胍基乙酸, 乙酸胍, 糖胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(=O)O)N=C(N)N
InChI: InChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; BPMFZUMJYQTVII-UHFFFAOYSA-N_STSL_0241_Glycocyamine_1000fmol_190403_S2_LC02MS02_057; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.

同义名列表

4 个代谢物同义名

2-Guanidinoacetic acid; glycocyamine; Guanidinoacetate; Glycocyamine



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(2)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

49 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AKT1, ALB, ARG1, ASL, ASS1, CBS, GAMT, MTOR, PRKAA2
Peripheral membrane protein 2 ACHE, MTOR
Endoplasmic reticulum membrane 1 MTOR
Nucleus 9 ACHE, AKT1, ALB, ARG1, BHMT, CBS, GAMT, MTOR, PRKAA2
cytosol 11 AKT1, ALB, ARG1, ASL, ASS1, B2M, BHMT, CBS, GAMT, MTOR, PRKAA2
dendrite 3 MTOR, PRKAA2, SLC6A6
phagocytic vesicle 1 MTOR
centrosome 1 ALB
nucleoplasm 5 AKT1, ASS1, ATP2B1, MTOR, PRKAA2
Cell membrane 8 ACHE, AKT1, ATP2B1, B2M, SLC16A12, SLC6A13, SLC6A6, SLC6A8
Cytoplasmic side 1 MTOR
lamellipodium 1 AKT1
Cytoplasmic granule 1 ARG1
Early endosome membrane 1 B2M
Multi-pass membrane protein 5 ATP2B1, SLC16A12, SLC6A13, SLC6A6, SLC6A8
Golgi apparatus membrane 1 MTOR
Synapse 2 ACHE, ATP2B1
cell cortex 1 AKT1
cell surface 2 ACHE, B2M
glutamatergic synapse 2 AKT1, ATP2B1
Golgi apparatus 4 ACHE, ALB, B2M, PRKAA2
Golgi membrane 3 B2M, INS, MTOR
lysosomal membrane 2 B2M, MTOR
mitochondrial inner membrane 1 GATM
neuromuscular junction 1 ACHE
neuronal cell body 2 PRKAA2, SLC6A6
postsynapse 1 AKT1
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 2 ASS1, BHMT
Lysosome 1 MTOR
Presynapse 1 SLC6A13
plasma membrane 8 ACHE, AKT1, ATP2B1, B2M, SLC16A12, SLC6A13, SLC6A6, SLC6A8
synaptic vesicle membrane 1 ATP2B1
Membrane 9 ACHE, AKT1, ATP2B1, B2M, MTOR, PRKAA2, SLC6A13, SLC6A6, SLC6A8
apical plasma membrane 2 SLC6A6, SLC6A8
axon 1 PRKAA2
basolateral plasma membrane 4 ATP2B1, SLC16A12, SLC6A13, SLC6A6
extracellular exosome 8 ALB, ASL, ASS1, ATP2B1, B2M, BHMT, GATM, SLC6A13
Lysosome membrane 1 MTOR
endoplasmic reticulum 2 ALB, B2M
extracellular space 6 ACHE, ALB, ARG1, B2M, IL6, INS
perinuclear region of cytoplasm 1 ACHE
mitochondrion 1 GATM
protein-containing complex 2 AKT1, ALB
intracellular membrane-bounded organelle 1 ATP2B1
Microsome membrane 1 MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 5 ACHE, ALB, B2M, IL6, INS
extracellular region 6 ACHE, ALB, ARG1, B2M, IL6, INS
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 2 ASS1, MTOR
Extracellular side 1 ACHE
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 1 B2M
perikaryon 1 ASS1
microtubule cytoskeleton 1 AKT1
cell-cell junction 1 AKT1
vesicle 1 AKT1
postsynaptic membrane 1 SLC6A6
Apical cell membrane 1 SLC6A8
Mitochondrion inner membrane 1 GATM
focal adhesion 1 B2M
spindle 1 AKT1
GABA-ergic synapse 1 SLC6A6
basement membrane 1 ACHE
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 2 AKT1, GATM
lateral plasma membrane 1 ATP2B1
nuclear speck 1 PRKAA2
ciliary basal body 2 AKT1, ALB
Late endosome membrane 1 B2M
cell projection 3 ATP2B1, SLC6A13, SLC6A6
phagocytic vesicle membrane 1 B2M
centriole 1 ALB
plasma membrane protein complex 1 SLC6A6
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 3 ATP2B1, SLC16A12, SLC6A13
Lipid-anchor, GPI-anchor 1 ACHE
microvillus membrane 1 SLC6A6
nuclear envelope 1 MTOR
Recycling endosome membrane 1 B2M
Endomembrane system 1 MTOR
endosome lumen 1 INS
cell body fiber 1 ASS1
cytoplasmic stress granule 1 PRKAA2
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
secretory granule lumen 1 INS
HFE-transferrin receptor complex 1 B2M
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, B2M, IL6, INS
platelet alpha granule lumen 1 ALB
specific granule lumen 2 ARG1, B2M
tertiary granule lumen 1 B2M
transport vesicle 1 INS
azurophil granule lumen 1 ARG1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
ER to Golgi transport vesicle membrane 1 B2M
synaptic cleft 1 ACHE
MHC class I peptide loading complex 1 B2M
nucleotide-activated protein kinase complex 1 PRKAA2
Cytoplasmic vesicle, phagosome 1 MTOR
MHC class I protein complex 1 B2M
MHC class II protein complex 1 B2M
interleukin-6 receptor complex 1 IL6
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
early endosome lumen 1 B2M


文献列表

  • J Dayan, Z Uni, F Soglia, M Zampiga, M Bordini, M Petracci, F Sirri. Dietary guanidinoacetate reduces spaghetti meat myopathy risk in the breast muscle of broiler chickens. Animal : an international journal of animal bioscience. 2024 May; 18(5):101144. doi: 10.1016/j.animal.2024.101144. [PMID: 38642412]
  • Yuan Su, Xinrui Li, Jiamin Zhao, Bingzhen Ji, Xiaoyi Zhao, Jinxin Feng, Junxing Zhao. Guanidinoacetic acid ameliorates hepatic steatosis and inflammation and promotes white adipose tissue browning in middle-aged mice with high-fat-diet-induced obesity. Food & function. 2024 Apr; 15(8):4515-4526. doi: 10.1039/d3fo05201j. [PMID: 38567805]
  • Douglas Janes, Blaine Suehs, Delbert M Gatlin. Dietary creatine and guanidinoacetic acid supplementation have limited effects on hybrid striped bass. Fish physiology and biochemistry. 2023 Apr; ?(?):. doi: 10.1007/s10695-023-01196-3. [PMID: 37069332]
  • M Majdeddin, U Braun, A Lemme, A Golian, H Kermanshahi, S De Smet, J Michiels. Effects of feeding guanidinoacetic acid on oxidative status and creatine metabolism in broilers subjected to chronic cyclic heat stress in the finisher phase. Poultry science. 2023 Mar; 102(6):102653. doi: 10.1016/j.psj.2023.102653. [PMID: 37030259]
  • Sergej M Ostojic. Cataloguing guanidinoacetic acid content in various foods. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2022 Jul; 92(3-4):158-160. doi: 10.1024/0300-9831/a000753. [PMID: 35291874]
  • Shiqi Zhang, Changjiang Zang, Jun Pan, Chen Ma, Caidie Wang, Xiaobin Li, Wenjie Cai, Kailun Yang. Effects of dietary guanidinoacetic acid on growth performance, guanidinoacetic acid absorption and creatine metabolism of lambs. PloS one. 2022; 17(3):e0264864. doi: 10.1371/journal.pone.0264864. [PMID: 35275964]
  • Bahram Miri, Hossein Ali Ghasemi, Iman Hajkhodadadi, Amir Hossein Khaltabadi Farahani. Effects of low eggshell temperatures during incubation, in ovo feeding of L-arginine, and post-hatch dietary guanidinoacetic acid on hatching traits, performance, and physiological responses of broilers reared at low ambient temperature. Poultry science. 2022 Jan; 101(1):101548. doi: 10.1016/j.psj.2021.101548. [PMID: 34823169]
  • Sergej M Ostojic. Safety of Dietary Guanidinoacetic Acid: A Villain of a Good Guy?. Nutrients. 2021 Dec; 14(1):. doi: 10.3390/nu14010075. [PMID: 35010949]
  • Mehrnaz Ardalan, Matt D Miesner, Christopher D Reinhardt, Daniel U Thomson, Cheryl K Armendariz, J Scott Smith, Evan C Titgemeyer. Effects of guanidinoacetic acid supplementation on nitrogen retention and methionine flux in cattle. Journal of animal science. 2021 Jun; 99(6):. doi: 10.1093/jas/skab172. [PMID: 34165572]
  • O Chandani Dinesh, Thillayampalam Kankayaliyan, Meike Rademacher, Christopher Tomlinson, Robert F Bertolo, Janet A Brunton. Neonatal Piglets Can Synthesize Adequate Creatine, but Only with Sufficient Dietary Arginine and Methionine, or with Guanidinoacetate and Excess Methionine. The Journal of nutrition. 2021 03; 151(3):531-539. doi: 10.1093/jn/nxaa369. [PMID: 33437999]
  • Sophia N Verouti, Delphine Lambert, Déborah Mathis, Ganesh Pathare, Geneviève Escher, Bruno Vogt, Daniel G Fuster. Solute carrier SLC16A12 is critical for creatine and guanidinoacetate handling in the kidney. American journal of physiology. Renal physiology. 2021 03; 320(3):F351-F358. doi: 10.1152/ajprenal.00475.2020. [PMID: 33459166]
  • Sergej M Ostojic, Nikola Todorovic, Valdemar Stajer. Effect of Creatine and Guanidinoacetate Supplementation on Plasma Homocysteine in Metabolically Healthy Men and Women. Annals of nutrition & metabolism. 2021; 77(5):307-308. doi: 10.1159/000518126. [PMID: 34515059]
  • Dandan Jiang, Limei Duan, Qiong Jia, Jinghai Liu. Glycocyamine functionalized magnetic layered double hydroxides with multiple affinity sites for trace phosphopeptides enrichment. Analytica chimica acta. 2020 Nov; 1136(?):25-33. doi: 10.1016/j.aca.2020.07.057. [PMID: 33081946]
  • Ryuta Jomura, Yu Tanno, Shin-Ichi Akanuma, Yoshiyuki Kubo, Masanori Tachikawa, Ken-Ichi Hosoya. Monocarboxylate transporter 12 as a guanidinoacetate efflux transporter in renal proximal tubular epithelial cells. Biochimica et biophysica acta. Biomembranes. 2020 11; 1862(11):183434. doi: 10.1016/j.bbamem.2020.183434. [PMID: 32781157]
  • Hannah F Speer, Kimberly A Pearl, Evan C Titgemeyer. Relative bioavailability of guanidinoacetic acid delivered ruminally or abomasally to cattle. Journal of animal science. 2020 Sep; 98(9):. doi: 10.1093/jas/skaa282. [PMID: 32845973]
  • M Majdeddin, U Braun, A Lemme, A Golian, H Kermanshahi, S De Smet, J Michiels. Guanidinoacetic acid supplementation improves feed conversion in broilers subjected to heat stress associated with muscle creatine loading and arginine sparing. Poultry science. 2020 Sep; 99(9):4442-4453. doi: 10.1016/j.psj.2020.05.023. [PMID: 32867988]
  • Sergej M Ostojic. Human gut microbiota as a source of guanidinoacetic acid. Medical hypotheses. 2020 Sep; 142(?):109745. doi: 10.1016/j.mehy.2020.109745. [PMID: 32344286]
  • Yiwen Zhang, Hang Zhou, Yong Tao, Baixue Lin. Reconstitution of the Ornithine Cycle with Arginine:Glycine Amidinotransferase to Engineer Escherichia coli into an Efficient Whole-Cell Catalyst of Guanidinoacetate. ACS synthetic biology. 2020 08; 9(8):2066-2075. doi: 10.1021/acssynbio.0c00138. [PMID: 32702969]
  • A A Çenesiz, İ Yavaş, İ Çiftci, N Ceylan, H O Taşkesen. Guanidinoacetic acid supplementation is favourable to broiler diets even containing poultry by-product meal. British poultry science. 2020 Jun; 61(3):311-319. doi: 10.1080/00071668.2020.1720909. [PMID: 32019332]
  • Trevor Kirby, Dana C Walters, Madalyn Brown, Erwin Jansen, Gajja S Salomons, Coleman Turgeon, Piero Rinaldo, Erland Arning, Paula Ashcraft, Teodoro Bottiglieri, Jean-Baptiste Roullet, K Michael Gibson. Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes. Metabolic brain disease. 2020 04; 35(4):601-614. doi: 10.1007/s11011-020-00550-1. [PMID: 32172518]
  • O Chandani Dinesh, Janet A Brunton, Robert F Bertolo. The Kidneys Are Quantitatively More Important than Pancreas and Gut as a Source of Guanidinoacetic Acid for Hepatic Creatine Synthesis in Sow-Reared Yucatan Miniature Piglets. The Journal of nutrition. 2020 03; 150(3):443-449. doi: 10.1093/jn/nxz266. [PMID: 31687740]
  • Mehrnaz Ardalan, Erick D Batista, Evan C Titgemeyer. Effect of post-ruminal guanidinoacetic acid supplementation on creatine synthesis and plasma homocysteine concentrations in cattle. Journal of animal science. 2020 Mar; 98(3):. doi: 10.1093/jas/skaa072. [PMID: 32152623]
  • Juan C Marini. Channeling of Citrulline for the Renal Synthesis of Guanidino Acetate. The Journal of nutrition. 2020 03; 150(3):423-424. doi: 10.1093/jn/nxz310. [PMID: 31868220]
  • Abeer Aziza, Rania Mahmoud, Eman Zahran, Hossam Gadalla. Dietary supplementation of guanidinoacetic acid improves growth, biochemical parameters, antioxidant capacity and cytokine responses in Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology. 2020 Feb; 97(?):367-374. doi: 10.1016/j.fsi.2019.12.052. [PMID: 31866449]
  • Sergej M Ostojic, Laszlo Ratgeber, Andras Olah, Jozsef Betlehem, Pongras Acs. Guanidinoacetic acid deficiency: a new entity in clinical medicine?. International journal of medical sciences. 2020; 17(16):2544-2550. doi: 10.7150/ijms.47757. [PMID: 33029096]
  • A Olah, V Stajer, L Ratgeber, J Betlehem, S M Ostojic. Age-Related Changes in Serum Guanidinoacetic Acid in Women. Physiological research. 2019 12; 68(6):1033-1036. doi: 10.33549/physiolres.934189. [PMID: 31647299]
  • Erik Hanff, Mohammad Yusof Said, Arslan Arinc Kayacelebi, Adrian Post, Isidor Minovic, Else van den Berg, Martin H de Borst, Harry van Goor, Stephan J L Bakker, Dimitrios Tsikas. High plasma guanidinoacetate-to-homoarginine ratio is associated with high all-cause and cardiovascular mortality rate in adult renal transplant recipients. Amino acids. 2019 Nov; 51(10-12):1485-1499. doi: 10.1007/s00726-019-02783-6. [PMID: 31535220]
  • L Zhang, J L Li, X F Wang, X D Zhu, F Gao, G H Zhou. Attenuating effects of guanidinoacetic acid on preslaughter transport-induced muscle energy expenditure and rapid glycolysis of broilers. Poultry science. 2019 Aug; 98(8):3223-3232. doi: 10.3382/ps/pez052. [PMID: 30789221]
  • Rucheton Benoit, Mesli Samir, Julian Boutin, Amintas Samuel, Colombies Brigitte, Ducint Dominique, Redonnet-Vernhet Isabelle. LC-MS/MS measurements of urinary guanidinoacetic acid and creatine: Method optimization by deleting derivatization step. Clinica chimica acta; international journal of clinical chemistry. 2019 Jun; 493(?):148-155. doi: 10.1016/j.cca.2019.03.007. [PMID: 30858092]
  • Dongting He, Libin Yang, Juntao Li, Bing Dong, Wenqing Lai, Liying Zhang. Effects of guanidinoacetic acid on growth performance, creatine metabolism and plasma amino acid profile in broilers. Journal of animal physiology and animal nutrition. 2019 May; 103(3):766-773. doi: 10.1111/jpn.13081. [PMID: 30941826]
  • S S Ale Saheb Fosoul, A Azarfar, A Gheisari, H Khosravinia. Performance and physiological responses of broiler chickens to supplemental guanidinoacetic acid in arginine-deficient diets. British poultry science. 2019 Apr; 60(2):161-168. doi: 10.1080/00071668.2018.1562156. [PMID: 30595031]
  • Sasa Semeredi, Valdemar Stajer, Jelena Ostojic, Milan Vranes, Sergej M Ostojic. Guanidinoacetic acid with creatine compared with creatine alone for tissue creatine content, hyperhomocysteinemia, and exercise performance: A randomized, double-blind superiority trial. Nutrition (Burbank, Los Angeles County, Calif.). 2019 01; 57(?):162-166. doi: 10.1016/j.nut.2018.04.009. [PMID: 30170305]
  • Pavle Jovanov, Milan Vraneš, Marijana Sakač, Slobodan Gadžurić, Jovana Panić, Aleksandar Marić, Sergej Ostojić. Hydrophilic interaction chromatography coupled to tandem mass spectrometry as a method for simultaneous determination of guanidinoacetate and creatine. Analytica chimica acta. 2018 Oct; 1028(?):96-103. doi: 10.1016/j.aca.2018.03.038. [PMID: 29884358]
  • Erik Hanff, Patricia Hafner, Alexander Bollenbach, Ulrike Bonati, Arslan Arinc Kayacelebi, Dirk Fischer, Dimitrios Tsikas. Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications. Amino acids. 2018 Oct; 50(10):1391-1406. doi: 10.1007/s00726-018-2614-7. [PMID: 30003335]
  • Jiaolong Li, Lin Zhang, Yanan Fu, Yanjiao Li, Yun Jiang, Guanghong Zhou, Feng Gao. Creatine Monohydrate and Guanidinoacetic Acid Supplementation Affects the Growth Performance, Meat Quality, and Creatine Metabolism of Finishing Pigs. Journal of agricultural and food chemistry. 2018 Sep; 66(38):9952-9959. doi: 10.1021/acs.jafc.8b02534. [PMID: 30173511]
  • Zhenzhao Wang, Rui Xu, Guiping Shen, Jianghua Feng. Metabolic Response in Rabbit Urine to Occurrence and Relief of Unilateral Ureteral Obstruction. Journal of proteome research. 2018 09; 17(9):3184-3194. doi: 10.1021/acs.jproteome.8b00304. [PMID: 30024170]
  • D T He, X R Gai, L B Yang, J T Li, W Q Lai, X L Sun, L Y Zhang. Effects of guanidinoacetic acid on growth performance, creatine and energy metabolism, and carcass characteristics in growing-finishing pigs. Journal of animal science. 2018 Jul; 96(8):3264-3273. doi: 10.1093/jas/sky186. [PMID: 29741632]
  • Sayed Sadra Ale Saheb Fosoul, Arash Azarfar, Abbasali Gheisari, Heshmatollah Khosravinia. Energy utilisation of broiler chickens in response to guanidinoacetic acid supplementation in diets with various energy contents. The British journal of nutrition. 2018 07; 120(2):131-140. doi: 10.1017/s0007114517003701. [PMID: 29690949]
  • Valdemar Stajer, Milan Vranes, Vladan Kocic, Sergej M Ostojic. Serum creatine is not a reliable marker of muscular fitness in young adults. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2018 Jul; 23(5):422-424. doi: 10.1080/1354750x.2018.1438514. [PMID: 29409353]
  • H A Córdova-Noboa, E O Oviedo-Rondón, A H Sarsour, J Barnes, D Sapcota, D López, L Gross, M Rademacher-Heilshorn, U Braun. Effect of guanidinoacetic acid supplementation on live performance, meat quality, pectoral myopathies and blood parameters of male broilers fed corn-based diets with or without poultry by-products. Poultry science. 2018 Jul; 97(7):2494-2505. doi: 10.3382/ps/pey097. [PMID: 29669035]
  • Behnam Ahmadipour, Mohammadreza Sharifi, Fariborz Khajali. Pulmonary hypertensive response of broiler chickens to arginine and guanidinoacetic acid under high-altitude hypoxia. Acta veterinaria Hungarica. 2018 03; 66(1):116-124. doi: 10.1556/004.2018.011. [PMID: 29580081]
  • A A DeGroot, U Braun, R N Dilger. Efficacy of guanidinoacetic acid on growth and muscle energy metabolism in broiler chicks receiving arginine-deficient diets. Poultry science. 2018 Mar; 97(3):890-900. doi: 10.3382/ps/pex378. [PMID: 29294127]
  • Masanori Tachikawa, Ayane Yashiki, Shin-Ichi Akanuma, Haruka Matsukawa, Soichiro Ide, Masabumi Minami, Ken-Ichi Hosoya. Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain. Neurochemistry international. 2018 02; 113(?):1-7. doi: 10.1016/j.neuint.2017.11.013. [PMID: 29175673]
  • Sergej M Ostojic, Milan Vranes, Davor Loncar, Natasa Zenic, Damir Sekulic. Guanidinoacetic Acid and Creatine are Associated with Cardiometabolic Risk Factors in Healthy Men and Women: A Cross-Sectional Study. Nutrients. 2018 Jan; 10(1):. doi: 10.3390/nu10010087. [PMID: 29342866]
  • O Chandani Dinesh, Robert F Bertolo, Janet A Brunton. Creatine supplementation to total parenteral nutrition improves creatine status and supports greater liver and kidney protein synthesis in neonatal piglets. Pediatric research. 2018 01; 83(1-1):135-141. doi: 10.1038/pr.2017.208. [PMID: 28846669]
  • Duygu Naile Günes, Arslan Arinc Kayacelebi, Erik Hanff, Joel Lundgren, Björn Redfors, Dimitrios Tsikas. Metabolism and distribution of pharmacological homoarginine in plasma and main organs of the anesthetized rat. Amino acids. 2017 Dec; 49(12):2033-2044. doi: 10.1007/s00726-017-2465-7. [PMID: 28710553]
  • Xiaofei Yin, Helena Gibbons, Milena Rundle, Gary Frost, Breige A McNulty, Anne P Nugent, Janette Walton, Albert Flynn, Michael J Gibney, Lorraine Brennan. Estimation of Chicken Intake by Adults Using Metabolomics-Derived Markers. The Journal of nutrition. 2017 Oct; 147(10):1850-1857. doi: 10.3945/jn.117.252197. [PMID: 28794208]
  • Syed Baharom, Robert De Matteo, Stacey Ellery, Paul Della Gatta, Clinton R Bruce, Greg M Kowalski, Nadia Hale, Hayley Dickinson, Richard Harding, David Walker, Rodney J Snow. Does maternal-fetal transfer of creatine occur in pregnant sheep?. American journal of physiology. Endocrinology and metabolism. 2017 07; 313(1):E75-E83. doi: 10.1152/ajpendo.00450.2016. [PMID: 28325734]
  • Ramin Shahabi Tapeh, Mahdi Zhandi, Mojtaba Zaghari, Amir Akhlaghi. Effects of guanidinoacetic acid diet supplementation on semen quality and fertility of broiler breeder roosters. Theriogenology. 2017 Feb; 89(?):178-182. doi: 10.1016/j.theriogenology.2016.11.012. [PMID: 28043349]
  • Sergej M Ostojic. Tackling guanidinoacetic acid for advanced cellular bioenergetics. Nutrition (Burbank, Los Angeles County, Calif.). 2017 Feb; 34(?):55-57. doi: 10.1016/j.nut.2016.09.010. [PMID: 28063512]
  • Sergej M Ostojic, Jelena Ostojic, Patrik Drid, Milan Vranes, Pavle Jovanov. Dietary guanidinoacetic acid increases brain creatine levels in healthy men. Nutrition (Burbank, Los Angeles County, Calif.). 2017 Jan; 33(?):149-156. doi: 10.1016/j.nut.2016.06.001. [PMID: 27497517]
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