Piperidine (BioDeep_00000400257)
Main id: BioDeep_00000003051
natural product PANOMIX_OTCML-2023
代谢物信息卡片
Piperidine
化学式: C5H11N (85.0891446)
中文名称: 六氢吡啶
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c1ccncc1
InChI: InChI=1/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2
描述信息
An azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine.
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators
同义名列表
1 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:18049
- KEGG: C01746
- PubChem: 8082
- ChEMBL: CHEMBL15487
- CAS: 89014-30-2
- CAS: 110-89-4
- MoNA: PT103233
- MetaboLights: MTBLC18049
- PubChem: 4880
- PDB-CCD: PIP
- 3DMET: B00341
- NIKKAJI: J2.884C
- RefMet: Piperidine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 3483 - Cannabis sativa: 10.1021/NP50008A001
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
- 13216 - Piper nigrum:
- 5691 - Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kazuki Hashiba, Masamitsu Taguchi, Sachiko Sakamoto, Ayaka Otsu, Yoshiki Maeda, Hirofumi Ebe, Arimichi Okazaki, Hideyoshi Harashima, Yusuke Sato. Overcoming thermostability challenges in mRNA-lipid nanoparticle systems with piperidine-based ionizable lipids.
Communications biology.
2024 May; 7(1):556. doi:
10.1038/s42003-024-06235-0. [PMID: 38730092] - Lav Singh, Atul K Upadhyay, Pooja Dixit, Arpit Singh, Divyanshu Yadav, Apurv Chhavi, Suraj Konar, Ravi Prakash Srivastava, Shivaraman Pandey, Hari Prasad Devkota, Praveen C Verma, Gauri Saxena. A Review of Chemistry and Pharmacology of Piperidine Alkaloids of Pinus and Related Genera.
Current pharmaceutical biotechnology.
2022; 23(9):1132-1141. doi:
10.2174/1389201022666210812123815. [PMID: 34387162] - Adedamola A Opalade, Elizabeth N Grotemeyer, Timothy A Jackson. Mimicking Elementary Reactions of Manganese Lipoxygenase Using Mn-hydroxo and Mn-alkylperoxo Complexes.
Molecules (Basel, Switzerland).
2021 Nov; 26(23):. doi:
10.3390/molecules26237151. [PMID: 34885729] - Botao Cheng, Heng Guo, Haoyang Wang, Qunfei Zhao, Wen Liu. Dissection of the Enzymatic Process for Forming a Central Imidazopiperidine Heterocycle in the Biosynthesis of a Series c Thiopeptide Antibiotic.
Journal of the American Chemical Society.
2021 09; 143(34):13790-13797. doi:
10.1021/jacs.1c05956. [PMID: 34405994] - Ryan S Nett, Yaereen Dho, Yun-Yee Low, Elizabeth S Sattely. A metabolic regulon reveals early and late acting enzymes in neuroactive Lycopodium alkaloid biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America.
2021 06; 118(24):. doi:
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2020 12; 63(24):15864-15882. doi:
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2019 01; 176(1):110-126. doi:
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Bioorganic & medicinal chemistry.
2018 12; 26(22):5816-5823. doi:
10.1016/j.bmc.2018.10.032. [PMID: 30413343] - Hidekazu Tokuhara, Yasuhiro Imaeda, Yoshiyuki Fukase, Koichi Iwanaga, Naohiro Taya, Koji Watanabe, Ray Kanagawa, Keisuke Matsuda, Yumiko Kajimoto, Keiji Kusumoto, Mitsuyo Kondo, Gyorgy Snell, Craig A Behnke, Takanobu Kuroita. Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profile.
Bioorganic & medicinal chemistry.
2018 07; 26(12):3261-3286. doi:
10.1016/j.bmc.2018.04.051. [PMID: 29754833] - Qi-Bin Chen, Jie Gao, Guo-An Zou, Xue-Lei Xin, Haji Akber Aisa. Piperidine Alkaloids with Diverse Skeletons from Anacyclus pyrethrum.
Journal of natural products.
2018 06; 81(6):1474-1482. doi:
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Molecules (Basel, Switzerland).
2017 Dec; 22(12):. doi:
10.3390/molecules22122085. [PMID: 29232885] - Jian-Cheng Ni, Jian-Ting Shi, Qing-Wei Tan, Qi-Jian Chen. Phenylpropionamides, Piperidine, and Phenolic Derivatives from the Fruit of Ailanthus altissima.
Molecules (Basel, Switzerland).
2017 Dec; 22(12):. doi:
10.3390/molecules22122107. [PMID: 29207525] - Surya N Meena, Mahesh S Majik, Sanjeev C Ghadi, Santosh G Tilve. Quick Identification of Piperidine Alkaloid from Roots of Grewia nervosa and Their Glucosidase Inhibitory Activity.
Chemistry & biodiversity.
2017 Dec; 14(12):. doi:
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2017 10; 60(20):8466-8481. doi:
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European journal of medicinal chemistry.
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2017 Jan; 89(1):247-261. doi:
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Chemistry & biology.
2013 Mar; 20(3):379-90. doi:
10.1016/j.chembiol.2013.01.012. [PMID: 23521796] - Katarzyna Cieślik-Boczula, Rafał Michał Petrus, Gottfried Köhler, Tadeusz Lis, Aleksander Koll. Interaction of piperidin derivative of Mannich base with DPPC liposomes.
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PloS one.
2013; 8(9):e75040. doi:
10.1371/journal.pone.0075040. [PMID: 24086433] - Shezeng Li, Xixuan Jin, Jian Chen. Effects of piperidine and piperideine alkaloids from the venom of red imported fire ants, Solenopsis invicta Buren, on Pythium ultimum Trow growth in vitro and the application of piperideine alkaloids to control cucumber damping-off in the greenhouse.
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Molecular nutrition & food research.
2012 Jan; 56(1):30-52. doi:
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International journal of molecular sciences.
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Oncotarget.
2011 Dec; 2(12):1244-53. doi:
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Organic and medicinal chemistry letters.
2011 Nov; 1(1):15. doi:
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BMC cancer.
2011 Oct; 11(?):465. doi:
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Toxins.
2011 10; 3(10):1332-72. doi:
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Biochemical and biophysical research communications.
2011 Jul; 411(1):219-25. doi:
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BMC genomics.
2011 Jul; 12(?):343. doi:
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Malaria journal.
2011 Jun; 10(?):150. doi:
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Analytical and bioanalytical chemistry.
2011 May; 400(4):1137-44. doi:
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Indian journal of pharmacology.
2011 May; 43(3):296-9. doi:
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Journal of young pharmacists : JYP.
2011 Apr; 3(2):132-7. doi:
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Chemical research in toxicology.
2011 Mar; 24(3):357-70. doi:
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European journal of nuclear medicine and molecular imaging.
2011 Mar; 38(3):540-51. doi:
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Indian journal of pharmaceutical sciences.
2011 Mar; 73(2):171-8. doi:
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European journal of medicinal chemistry.
2011 Mar; 46(3):825-34. doi:
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Biochimica et biophysica acta.
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Bioorganic & medicinal chemistry letters.
2011 Mar; 21(5):1299-305. doi:
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PloS one.
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Advances in virology.
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PloS one.
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PloS one.
2011; 6(10):e25927. doi:
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BMC systems biology.
2011 Jan; 5(?):1. doi:
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Genome biology and evolution.
2011; 3(?):851-67. doi:
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PloS one.
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European journal of mass spectrometry (Chichester, England).
2011; 17(3):227-35. doi:
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Biopharmaceutics & drug disposition.
2011 Jan; 32(1):25-37. doi:
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mBio.
2011; 2(4):. doi:
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Perspectives in medicinal chemistry.
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PloS one.
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Archives of pharmacal research.
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Plant physiology.
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Journal of clinical biochemistry and nutrition.
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Plant physiology.
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Bioorganic & medicinal chemistry letters.
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PloS one.
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BMC plant biology.
2010 Jun; 10(?):130. doi:
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2010 Jun; 40(3):222-38. doi:
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Planta medica.
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