Biochanin A (BioDeep_00000397993)

Main id: BioDeep_00000000067

Secondary id: BioDeep_00000269990

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


4-Methylgenistein (Biochanin A)

化学式: C16H12O5 (284.0685)
中文名称: 鹰嘴豆芽素A, 5,7-二羟基-4'-甲氧基异黄酮
谱图信息: 最多检出来源 Homo sapiens(plant) 9.5%

分子结构信息

SMILES: COC1=CC=C(C=C1)C1=COC2=C(C(O)=CC(O)=C2)C1=O
InChI: InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3

描述信息

Annotation level-1
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.140
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents
D000970 - Antineoplastic Agents
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.141
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.139
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.137
IPB_RECORD: 2161; CONFIDENCE confident structure
Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.

同义名列表

5 个代谢物同义名

4-Methylgenistein (Biochanin A); Biochanin A; 4-Methylgenistein; Olmelin; Biochanin A



数据库引用编号

90 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

101 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 ABCB1, BCL2, BECN1, CASP3, ESR1, MAPK14, MAPK8, MTOR, NFE2L2, PIK3CA, PPARG, PTGS2, TNK1, TP53, VEGFA
Golgi apparatus, trans-Golgi network membrane 1 BECN1
Peripheral membrane protein 6 BECN1, CYP1B1, ESR1, MTOR, PTGS2, TNK1
Endosome membrane 1 BECN1
Endoplasmic reticulum membrane 6 BCL2, BECN1, CYP1B1, HMOX1, MTOR, PTGS2
Mitochondrion membrane 1 BECN1
Cytoplasmic vesicle, autophagosome 1 BECN1
Nucleus 12 BCL2, BECN1, CASP3, ESR1, HMOX1, MAPK14, MAPK8, MTOR, NFE2L2, PPARG, TP53, VEGFA
autophagosome 1 BECN1
cytosol 12 BCL2, BECN1, CASP3, ESR1, HMOX1, MAPK14, MAPK8, MTOR, NFE2L2, PIK3CA, PPARG, TP53
dendrite 2 BECN1, MTOR
mitochondrial membrane 1 BECN1
nuclear body 1 BECN1
phagocytic vesicle 2 BECN1, MTOR
phosphatidylinositol 3-kinase complex, class III 1 BECN1
trans-Golgi network 1 BECN1
centrosome 2 NFE2L2, TP53
nucleoplasm 9 CASP3, ESR1, HMOX1, MAPK14, MAPK8, MTOR, NFE2L2, PPARG, TP53
RNA polymerase II transcription regulator complex 2 NFE2L2, PPARG
Cell membrane 3 ABCB1, ESR1, TNF
Cytoplasmic side 3 ESR1, HMOX1, MTOR
lamellipodium 1 PIK3CA
Multi-pass membrane protein 1 ABCB1
Golgi apparatus membrane 1 MTOR
Synapse 1 MAPK8
cell surface 3 ABCB1, TNF, VEGFA
glutamatergic synapse 2 CASP3, MAPK14
Golgi apparatus 3 ESR1, NFE2L2, VEGFA
Golgi membrane 2 INS, MTOR
lysosomal membrane 1 MTOR
neuronal cell body 2 CASP3, TNF
Cytoplasm, cytosol 1 NFE2L2
Lysosome 1 MTOR
endosome 1 BECN1
plasma membrane 6 ABCB1, ESR1, NFE2L2, PIK3CA, TNF, TNK1
Membrane 9 ABCB1, BCL2, CYP1B1, ESR1, HMOX1, MTOR, TNK1, TP53, VEGFA
apical plasma membrane 1 ABCB1
axon 1 MAPK8
caveola 1 PTGS2
extracellular exosome 1 ABCB1
Lysosome membrane 1 MTOR
endoplasmic reticulum 6 BCL2, BECN1, HMOX1, PTGS2, TP53, VEGFA
extracellular space 5 HMOX1, IL6, INS, TNF, VEGFA
perinuclear region of cytoplasm 3 HMOX1, PIK3CA, PPARG
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
mitochondrion 4 BCL2, CYP1B1, MAPK14, TP53
protein-containing complex 4 BCL2, ESR1, PTGS2, TP53
intracellular membrane-bounded organelle 2 CYP1B1, PPARG
Microsome membrane 3 CYP1B1, MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 3 IL6, INS, VEGFA
extracellular region 5 IL6, INS, MAPK14, TNF, VEGFA
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
transcription regulator complex 2 ESR1, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
nucleolus 1 TP53
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ABCB1
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TP53
extracellular matrix 1 VEGFA
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
secretory granule 1 VEGFA
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 PPARG
neuron projection 1 PTGS2
chromatin 4 ESR1, NFE2L2, PPARG, TP53
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
spindle pole 1 MAPK14
site of double-strand break 1 TP53
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 1 INS
phagophore assembly site 1 BECN1
phosphatidylinositol 3-kinase complex, class III, type I 1 BECN1
phosphatidylinositol 3-kinase complex, class III, type II 1 BECN1
euchromatin 1 ESR1
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 2 INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
[Isoform 1]: Nucleus 2 ESR1, TP53
protein-DNA complex 1 NFE2L2
external side of apical plasma membrane 1 ABCB1
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, phagosome 1 MTOR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
cytoplasmic side of mitochondrial outer membrane 1 BECN1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[Beclin-1-C 35 kDa]: Mitochondrion 1 BECN1
[Beclin-1-C 37 kDa]: Mitochondrion 1 BECN1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Palash Mandal, David A Mortensen, André F Brito, Anna K Wallingford, Marta R M Lima, Nicholas D Warren, Richard G Smith. Water Stress Influences Phytoestrogen Levels in Red Clover (Trifolium pratense) but Not Kura Clover (T. ambiguum). Journal of agricultural and food chemistry. 2024 May; 72(18):10247-10256. doi: 10.1021/acs.jafc.4c00300. [PMID: 38683760]
  • Al-Sayeda Al-Sayed Newairy, Fatma Ahmad Hamaad, Mayssaa Moharm Wahby, Mamdooh Ghoneum, Heba Mohamed Abdou. Neurotherapeutic effects of quercetin-loaded nanoparticles and Biochanin-A extracted from Trifolium alexandrinum on PI3K/Akt/GSK-3β signaling in the cerebral cortex of male diabetic rats. PloS one. 2024; 19(4):e0301355. doi: 10.1371/journal.pone.0301355. [PMID: 38683825]
  • Huixin Tan, Fenghe Wang, Jiahuan Hu, Xiaoyan Duan, Wanting Bai, Xinbo Wang, Baolian Wang, Yan Su, Jinping Hu. Inhibitory interaction of flavonoids with organic cation transporter 2 and their structure-activity relationships for predicting nephroprotective effects. Journal of applied toxicology : JAT. 2023 Apr; ?(?):. doi: 10.1002/jat.4474. [PMID: 37057715]
  • Lovedeep Singh, Navneet Kaur, Rajbir Bhatti. Neuroprotective potential of biochanin-A and review of the molecular mechanisms involved. Molecular biology reports. 2023 Apr; ?(?):. doi: 10.1007/s11033-023-08397-2. [PMID: 37039995]
  • Meemansha Sharma, Thakur Uttam Singh, Abhinav Rana, Tarun Kumar, Manju Gari, Pashupathi Mani, Madhu Cholenahalli Lingaraju, Subhashree Parida, Vidya Singh, Monalisa Sahoo, Dinesh Kumar. Biochanin-A alleviates fibrosis and inflammation in cardiac injury in mice. Journal of biochemical and molecular toxicology. 2023 Apr; ?(?):e23360. doi: 10.1002/jbt.23360. [PMID: 37016276]
  • Guo-En Wang, Xiao-Ting Liu, Fan Yang, Ruo-Hong Wang, Xin-Yu Liu, Xi-Ting Lv, Xiao-Li Lin, Yan-Fen Chen. Biochanin A ameliorated oleate-induced steatosis in HepG2 cells by activating the SIRT3/AMPK/ULK-1 signaling pathway. Journal of food biochemistry. 2022 12; 46(12):e14428. doi: 10.1111/jfbc.14428. [PMID: 36125796]
  • Faryal Rubab, Hira Ijaz, Shah Hussain, Ans Munir, Stefan Stuppner, Thomas Jakschitz, Günther K Bonn, Saiqa Ishtiaq. Gastroprotective effects of Caragana ambigua stocks on ethanol-induced gastric ulcer in rats supported by LC-MS/MS characterization of formononetin and biochanin A. Journal of the science of food and agriculture. 2022 Dec; 102(15):7030-7038. doi: 10.1002/jsfa.12064. [PMID: 35689485]
  • B Haridevamuthu, Ajay Guru, Raghul Murugan, Gokul Sudhakaran, Raman Pachaiappan, Mikhlid H Almutairi, Bader O Almutairi, Annie Juliet, Jesu Arockiaraj. Neuroprotective effect of Biochanin a against Bisphenol A-induced prenatal neurotoxicity in zebrafish by modulating oxidative stress and locomotory defects. Neuroscience letters. 2022 Nov; 790(?):136889. doi: 10.1016/j.neulet.2022.136889. [PMID: 36179902]
  • Pengshou Li, Mengdan Li, Xinhua Lou, Baosheng Zhao, Qixiang Ma, Yumiao Bian, Xiliang Mi. Evaluation of Hypoglycemic Activity and Sub-Acute Toxicity of the Novel Biochanin A-Chromium(III) Complex. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27185786. [PMID: 36144522]
  • Swapnil Tripathi, Dharati Parmar, Shabrin Fathima, Samir Raval, Gyanendra Singh. Coenzyme Q10, Biochanin A and Phloretin Attenuate Cr(VI)-Induced Oxidative Stress and DNA Damage by Stimulating Nrf2/HO-1 Pathway in the Experimental Model. Biological trace element research. 2022 Aug; ?(?):. doi: 10.1007/s12011-022-03358-5. [PMID: 35953644]
  • Nadja Kampschulte, Tim Berking, Ibrahim E Çelik, Stefan F Kirsch, Nils Helge Schebb. Inhibition of cytochrome P450 monooxygenase-catalyzed oxylipin formation by flavonoids: Evaluation of structure-activity relationship towards CYP4F2-selective inhibitors. European journal of medicinal chemistry. 2022 Aug; 238(?):114332. doi: 10.1016/j.ejmech.2022.114332. [PMID: 35576701]
  • Chetan Ram, Shobhit Gairola, Abu Mohammad Syed, Uttam Kulhari, Sourav Kundu, Madhav Nilakanth Mugale, Upadhyayula Suryanarayana Murty, Bidya Dhar Sahu. Biochanin A alleviates unilateral ureteral obstruction-induced renal interstitial fibrosis and inflammation by inhibiting the TGF-β1/Smad2/3 and NF-kB/NLRP3 signaling axis in mice. Life sciences. 2022 Jun; 298(?):120527. doi: 10.1016/j.lfs.2022.120527. [PMID: 35378138]
  • Swapnil Tripathi, Shabrin Fhatima, Dharati Parmar, Dhirendra Pratap Singh, SukhDev Mishra, Rajeev Mishra, Gyanendra Singh. Therapeutic effects of CoenzymeQ10, Biochanin A and Phloretin against arsenic and chromium induced oxidative stress in mouse (Mus musculus) brain. 3 Biotech. 2022 May; 12(5):116. doi: 10.1007/s13205-022-03171-w. [PMID: 35547012]
  • Mohamed Mahmoud, Maha R A Abdollah, Mohamed E Elsesy, Dalal A Abou El Ella, Suher K Zada, Mai F Tolba. The natural isoflavone Biochanin-A synergizes 5-fluorouracil anticancer activity in vitro and in vivo in Ehrlich solid-phase carcinoma model. Phytotherapy research : PTR. 2022 Mar; 36(3):1310-1325. doi: 10.1002/ptr.7388. [PMID: 35112408]
  • Manisha J Oza, Yogesh A Kulkarni. Biochanin A Attenuates Cardiomyopathy in Type 2 Diabetic Rats by Increasing SIRT1 Expression and Reducing Oxidative Stress. Chemistry & biodiversity. 2022 Mar; 19(3):e202100591. doi: 10.1002/cbdv.202100591. [PMID: 35119190]
  • Jingru Qin, Chao Guo, Lu Yang, Xiao Liang, Aijun Jiao, Keng Po Lai, Bin Yang. Bioinformatics and in-silico findings reveal medical features and pharmacological targets of biochanin A against colorectal cancer and COVID-19. Bioengineered. 2021 12; 12(2):12461-12469. doi: 10.1080/21655979.2021.2005876. [PMID: 34931923]
  • Yi-Gui Yu, Jun-Hui Han, Hai-Xia Xue, Wei-Zu Li, Wen-Ning Wu, Yan-Yan Yin. The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A. Canadian journal of physiology and pharmacology. 2021 Dec; 99(12):1298-1307. doi: 10.1139/cjpp-2021-0013. [PMID: 34310897]
  • Gyanendra Singh, Riddhi Thaker, Anupama Sharma, Dharati Parmar. Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice. Environmental science and pollution research international. 2021 Apr; 28(16):20517-20536. doi: 10.1007/s11356-020-11740-w. [PMID: 33410021]
  • Kai-Xuan Hu, Xin-Chi Shi, Dong Xu, Pablo Laborda, Gui-Chun Wu, Feng-Quan Liu, Pedro Laborda, Su-Yan Wang. Antibacterial mechanism of Biochanin A and its efficacy for the control of Xanthomonas axonopodis pv. glycines in soybean. Pest management science. 2021 Apr; 77(4):1668-1673. doi: 10.1002/ps.6186. [PMID: 33202090]
  • Dong-Jun Fu, Jun Li, Bin Yu. Annual review of LSD1/KDM1A inhibitors in 2020. European journal of medicinal chemistry. 2021 Mar; 214(?):113254. doi: 10.1016/j.ejmech.2021.113254. [PMID: 33581557]
  • Ankur Kumar Tanwar, Neha Dhiman, Amit Kumar, Vikas Jaitak. Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. European journal of medicinal chemistry. 2021 Mar; 213(?):113037. doi: 10.1016/j.ejmech.2020.113037. [PMID: 33257172]
  • Randy D Dinkins, Julie Hancock, Brenda L Coe, John B May, Jack P Goodman, William T Bass, Jinge Liu, Yinglun Fan, Qiaolin Zheng, Hongyan Zhu. Isoflavone levels, nodulation and gene expression profiles of a CRISPR/Cas9 deletion mutant in the isoflavone synthase gene of red clover. Plant cell reports. 2021 Mar; 40(3):517-528. doi: 10.1007/s00299-020-02647-4. [PMID: 33389047]
  • Jansy Isabella Rani A, V V Sathibabu Uddandrao, Sangeethadevi G, Saravanan G, Chandrasekaran P, Sengottuvelu S, Tamilmani P, Sethumathi P P, S Vadivukkarasi. Biochanin A attenuates obesity cardiomyopathy in rats by inhibiting oxidative stress and inflammation through the Nrf-2 pathway. Archives of physiology and biochemistry. 2021 Jan; ?(?):1-16. doi: 10.1080/13813455.2021.1874017. [PMID: 33471570]
  • Jia Yan, Panda Qiu, Xinyu Zhang, Yuanyuan Zhang, Linjing Mi, Cheng Peng, Xiaoqi Pan, Fu Peng. Biochanin A from Chinese Medicine: An Isoflavone with Diverse Pharmacological Properties. The American journal of Chinese medicine. 2021; 49(7):1623-1643. doi: 10.1142/s0192415x21500750. [PMID: 34530697]
  • Min-Min Guo, Sheng-Biao Qu, Hui-Ling Lu, Wen-Bo Wang, Mu-Liang He, Jian-Lin Su, Jian Chen, Yong Wang. Biochanin A Alleviates Cerebral Ischemia/Reperfusion Injury by Suppressing Endoplasmic Reticulum Stress-Induced Apoptosis and p38MAPK Signaling Pathway In Vivo and In Vitro. Frontiers in endocrinology. 2021; 12(?):646720. doi: 10.3389/fendo.2021.646720. [PMID: 34322090]
  • Zhaohui Xue, Ang Li, Xueya Zhang, Wancong Yu, Junyu Wang, Yong Li, Kui Chen, Zhongliang Wang, Xiaohong Kou. Amelioration of PM2.5-induced lung toxicity in rats by nutritional supplementation with biochanin A. Ecotoxicology and environmental safety. 2020 Oct; 202(?):110878. doi: 10.1016/j.ecoenv.2020.110878. [PMID: 32585486]
  • Xiaoqing Fan, Jie Bai, Minwan Hu, Yanxia Xu, Shengyu Zhao, Yanhong Sun, Baolian Wang, Jinping Hu, Yan Li. Drug interaction study of flavonoids toward OATP1B1 and their 3D structure activity relationship analysis for predicting hepatoprotective effects. Toxicology. 2020 05; 437(?):152445. doi: 10.1016/j.tox.2020.152445. [PMID: 32259555]
  • Weie Zhou, Hanqiu Wu, Qian Wang, Xuefeng Zhou, Yuan Zhang, Wenjie Wu, Yuyang Wang, Zhiqin Ren, Hongna Li, Yun Ling, Feng Zhang, Ping Li. Simultaneous determination of formononetin, biochanin A and their active metabolites in human breast milk, saliva and urine using salting-out assisted liquid-liquid extraction and ultra high performance liquid chromatography-electrospray ionization tandem mass spectrum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2020 May; 1145(?):122108. doi: 10.1016/j.jchromb.2020.122108. [PMID: 32305709]
  • Jing-Ran Fan, Yi Kuang, Ze-Yuan Dong, Yang Yi, Yan-Xia Zhou, Bin Li, Xue Qiao, Min Ye. Prenylated Phenolic Compounds from the Aerial Parts of Glycyrrhiza uralensis as PTP1B and α-Glucosidase Inhibitors. Journal of natural products. 2020 04; 83(4):814-824. doi: 10.1021/acs.jnatprod.9b00262. [PMID: 32196343]
  • Xiao-Hua Yu, Jiao-Jiao Chen, Wen-Yi Deng, Xiao-Dan Xu, Qi-Xian Liu, Meng-Wen Shi, Kun Ren. Biochanin A Mitigates Atherosclerosis by Inhibiting Lipid Accumulation and Inflammatory Response. Oxidative medicine and cellular longevity. 2020; 2020(?):8965047. doi: 10.1155/2020/8965047. [PMID: 33959213]
  • Jansy Isabella Rani Antony Rathinasamy, Veera Venkata Sathibabu Uddandrao, Nivedha Raveendran, Vadivukkarasi Sasikumar. Antiobesity Effect of Biochanin-A: Effect on Trace Element Metabolism in High Fat Diet-Induced Obesity in Rats. Cardiovascular & hematological agents in medicinal chemistry. 2020; 18(1):21-30. doi: 10.2174/1871524920666200207101920. [PMID: 32031077]
  • Sangeethadevi Govindasami, Veera Venkata Sathibabu Uddandrao, Nivedha Raveendran, Vadivukkarasi Sasikumar. Therapeutic Potential of Biochanin-A Against Isoproterenol-Induced Myocardial Infarction in Rats. Cardiovascular & hematological agents in medicinal chemistry. 2020; 18(1):31-36. doi: 10.2174/1871525718666200206114304. [PMID: 32026788]
  • Gonzalo R Malca Garcia, J Brent Friesen, Yang Liu, Dejan Nikolić, David C Lankin, James B McAlpine, Shao-Nong Chen, Guido F Pauli. Preparation of DESIGNER extracts of red clover (Trifolium pratense L.) by centrifugal partition chromatography. Journal of chromatography. A. 2019 Nov; 1605(?):360277. doi: 10.1016/j.chroma.2019.05.057. [PMID: 31307793]
  • Kanumuri Siva Rama Raju, Mamunur Rashid, Manoj Gundeti, Isha Taneja, Mohd Yaseen Malik, Sandeep Kumar Singh, Swati Chaturvedi, Muralikrishna Challagundla, Sheelendra Pratap Singh, J R Gayen, Muhammad Wahajuddin. LC-ESI-MS/MS method for the simultaneous determination of isoformononetin, daidzein, and equol in rat plasma: Application to a preclinical pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Oct; 1129(?):121776. doi: 10.1016/j.jchromb.2019.121776. [PMID: 31629309]
  • Anna M Chrzanowska, Myriam Díaz-Álvarez, Piotr P Wieczorek, Anna Poliwoda, Antonio Martín-Esteban. The application of the supported liquid membrane and molecularly imprinted polymers as solid acceptor phase for selective extraction of biochanin A from urine. Journal of chromatography. A. 2019 Aug; 1599(?):9-16. doi: 10.1016/j.chroma.2019.04.005. [PMID: 30975528]
  • Ludmila Křížová, Kateřina Dadáková, Jitka Kašparovská, Tomáš Kašparovský. Isoflavones. Molecules (Basel, Switzerland). 2019 Mar; 24(6):. doi: 10.3390/molecules24061076. [PMID: 30893792]
  • Eun Mi Choi, Kwang Sik Suh, So Young Park, Sang Ouk Chin, Sang Youl Rhee, Suk Chon. Biochanin A prevents 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced adipocyte dysfunction in cultured 3T3-L1 cells. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2019; 54(9):865-873. doi: 10.1080/10934529.2019.1603746. [PMID: 31007129]
  • Anna Fickler, Stefanie Staats, Gerald Rimbach, Carsten Schulz. Screening dietary biochanin A, daidzein, equol and genistein for their potential to increase DHA biosynthesis in rainbow trout (Oncorhynchus mykiss). PloS one. 2019; 14(1):e0210197. doi: 10.1371/journal.pone.0210197. [PMID: 30645603]
  • Yejun Bai, Zhigang Li, Weihao Liu, Dong Gao, Min Liu, Peiying Zhang. Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway. Acta cirurgica brasileira. 2019; 34(11):e201901104. doi: 10.1590/s0102-865020190110000004. [PMID: 31859817]
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