3,3',4'5-Tetrahydroxystilbene (BioDeep_00000000350)

 

Secondary id: BioDeep_00000406165

human metabolite PANOMIX_OTCML-2023 Endogenous Chemicals and Drugs


代谢物信息卡片


(E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol, 3,3a?4,5a?Tetrahydroxy-trans-stilbene

化学式: C14H12O4 (244.0735552)
中文名称: 白皮杉醇, 白皮杉醇
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 0.62%

分子结构信息

SMILES: C1=C(O)C=C(/C=C/C2=CC(O)=C(O)C=C2)C=C1O
InChI: InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+

描述信息

Piceatannol is a stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5. It has a role as a protein kinase inhibitor, a tyrosine kinase inhibitor, an antineoplastic agent, a plant metabolite, a hypoglycemic agent, an apoptosis inducer and a geroprotector. It is a stilbenol, a member of resorcinols, a member of catechols and a polyphenol. It derives from a hydride of a trans-stilbene.
Piceatannol is a natural product found in Vitis amurensis, Smilax bracteata, and other organisms with data available.
Piceatannol is a polyhydroxylated stilbene extract from the seeds of Euphorbia lagascae, which inhibits protein tyrosine kinase Syk and induces apoptosis. (NCI)
Piceatannol is a metabolite found in or produced by Saccharomyces cerevisiae.
See also: Wine grape (part of); Robinia pseudoacacia whole (part of); Tsuga canadensis bark (part of).
3,3,45-Tetrahydroxystilbene (or Piceatannol) is a phenolic stilbenoid. It is a metabolite of resveratrol found in red wine. A viral protein-tyrosine kinase (LMP2A) implicated in leukemia, non-Hodgkins lymphoma and other diseases associated with Epstein-Barr virus, was recently found to be blocked by picetannol in vitro (PMID 2590224). Therefore there is research interest in piceatannol as an anti-cancer and anti-EBV drug. Piceatannol can also act as an agonist for estrogen receptor alpha in human breast cancer cells (PMID: 16216908). [HMDB]
3,3,45-Tetrahydroxystilbene (or Piceatannol) is a phenolic stilbenoid. It is a metabolite of resveratrol found in red wine. A viral protein-tyrosine kinase (LMP2A) implicated in leukemia, non-Hodgkins lymphoma and other diseases associated with Epstein-Barr virus, was recently found to be blocked by picetannol in vitro (PMID 2590224). Therefore there is research interest in piceatannol as an anti-cancer and anti-EBV drug. Piceatannol can also act as an agonist for estrogen receptor alpha in human breast cancer cells (PMID: 16216908).
A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI)[1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties[2]. Piceatannol induces apoptosis in DLBCL cell lines[3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells[4].
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI)[1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties[2]. Piceatannol induces apoptosis in DLBCL cell lines[3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells[4].

同义名列表

69 个代谢物同义名

(E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol, 3,3a?4,5a?Tetrahydroxy-trans-stilbene; (E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol, 3,3,4,5-Tetrahydroxy-trans-stilbene; 4-[2-(3,5-dihydroxyphenyl)-(E)-1-ethenyl]-1,2-benzenediol(Piceatannol); 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol(Piceatannol); 1,2-Benzenediol, 4-[2-(3,5-dihydroxyphenyl)ethenyl]-, (E)-; 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-, (E)-; 4-[2-(3,5-dihydroxyphenyl)-(E)-1-ethenyl]-1,2-benzenediol; 1,2-BENZENEDIOL, 4-((1E)-2-(3,5-DIHYDROXYPHENYL)ETHENYL)-; 1,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-; 1,2-Benzenediol, 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]-; 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol; 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,2-benzenediol; 4-((1E)-2-(3,5-dihydroxyphenyl)ethenyl)benzene-1,2-diol; 5-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]benzene-1,3-diol; 4-((E)-2-(3,5-DIHYDROXYPHENYL)ETHENYL)BENZENE-1,2-DIOL; 4-[(E)-2-(3,5-DIHYDROXYPHENYL)ETHENYL]BENZENE-1,2-DIOL; 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol; (E)-4-[2-(3,5-Dihydroxyphenyl)ethenyl]1,2-benzenediol; 4-((E)-2-(3,5-DIHYDROXYPHENYL)VINYL)-1,2-BENZENEDIOL; 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol; 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-; 4-((E)-2-(3,5-dihydroxyphenyl)vinyl)benzene-1,2-diol; 5-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]benzene-1,3-diol; 1, 4-[2-(3,5-dihydroxyphenyl)ethenyl]-, (E)-; (E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol; 4-(3,5-dihydroxystyryl)benzene-1,2-diol; trans-3,3’,4,5’-Tetrahydroxystilbene; F13BE9BB-B7D7-4D40-B31A-C15B953E033D; 3,5,3,4-tetrahydroxy-trans-stilbene; 3,3,4,5-Tetrahydroxy-trans-stilbene; 3,4,3,5-tetrahydroxy-trans-stilbene; trans-3,3,4,5-tetrahydroxystilbene; trans-3,3,4,5-Tetrahydroxystilbene; 3,5,3,4-tetrahydroxy-stilbene; Astringenin;trans-Piceatannol; 3,3,4,5-tetrahydroxy stilbene; 3,4,3,5-tetrahydroxystillbene; 3,3,4,5-tetrahydroxystilbene; 3,3,4,5-STILBENETETROL, (E)-; (E)-3,3’,4,5’-Stilbenetetrol; 3,5,3,4-tetrahydroxystilbene; CDRPUGZCRXZLFL-OWOJBTEDSA-N; 3,3,45-Tetrahydroxystilbene; (E)-3,3,4,5-Stilbenetetrol; demethyl isorhapontigenin; 3,3,4,5-Stilbenetetrol; 3-Hydroxyresveratol; 3-hydroxyresveratol; Piceatannol, powder; PICEATANNOL [INCI]; trans-Piceatannol; BiomolKI2_000031; UNII-6KS3LS0D4F; (E)-Piceatannol; MEGxp0_000245; Lopac0_000915; Astringinine; Tox21_500915; SMP2_000263; Piceatannol; IDI1_002155; astringinin; Astringenin; piceatanol; 6KS3LS0D4F; BMK1-C11; C14H12O4; J61.264B; RSVL-1



数据库引用编号

25 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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224 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Pouya Goleij, Pantea Majma Sanaye, Mehregan Babamohamadi, Mohammad Amin Khazeei Tabari, Roshanak Amirian, Aryan Rezaee, Hamed Mirzaei, Alan Prem Kumar, Gautam Sethi, Sarvin Sadreddini, Philippe Jeandet, Haroon Khan. Phytostilbenes in lymphoma: Focuses on the mechanistic and clinical prospects of resveratrol, pterostilbene, piceatannol, and pinosylvin. Leukemia research. 2024 03; 138(?):107464. doi: 10.1016/j.leukres.2024.107464. [PMID: 38422882]
  • Min Zhu, En-Qing Lu, Yong-Xia Fang, Guo-Wei Liu, Yu-Jie Cheng, Ke Huang, E Xu, Yi-Yu Zhang, Xiao-Jing Wang. Piceatannol Alleviates Deoxynivalenol-Induced Damage in Intestinal Epithelial Cells via Inhibition of the NF-κB Pathway. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040855. [PMID: 38398607]
  • Mengmei Zhu, Tianhao Zhao, Binshan Zha, Guiyang Zhang, Weiwei Qian, Xinya Wang, Qiuju Zhao, Shuo Chen, Zeping Hu, Liuyi Dong. Piceatannol protects against myocardial ischemia/reperfusion injury by inhibiting ferroptosis via Nrf-2 signaling-mediated iron metabolism. Biochemical and biophysical research communications. 2024 Jan; 700(?):149598. doi: 10.1016/j.bbrc.2024.149598. [PMID: 38308910]
  • Manami Inoue, Yuki Nakagawa, Miku Azuma, Haruka Akahane, Ryusei Chimori, Yasunari Mano, Ryoko Takasawa. The PKM2 inhibitor shikonin enhances piceatannol-induced apoptosis of glyoxalase I-dependent cancer cells. Genes to cells : devoted to molecular & cellular mechanisms. 2023 Nov; ?(?):. doi: 10.1111/gtc.13084. [PMID: 37963646]
  • Lianghao Huang, Jinyu Wang, Xiaoyao Ma, Lishan Sun, Cui Hao, Wei Wang. Inhibition of influenza a virus infection by natural stilbene piceatannol targeting virus hemagglutinin. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Aug; 120(?):155058. doi: 10.1016/j.phymed.2023.155058. [PMID: 37690231]
  • Tarek Khamis, Abd Al-Aziz Abas Diab, Mansour H Zahra, Samih Ebrahim El-Dahmy, Basant Ahmed Abd Al-Hameed, Adel Abdelkhalek, Mahmoud A Said, Hussein Abdellatif, Liana Mihaela Fericean, Ioan Banatean-Dunea, Ahmed Hamed Arisha, Mai S Attia. The Antiproliferative Activity of Adiantum pedatum Extract and/or Piceatannol in Phenylhydrazine-Induced Colon Cancer in Male Albino Rats: The miR-145 Expression of the PI-3K/Akt/p53 and Oct4/Sox2/Nanog Pathways. Molecules (Basel, Switzerland). 2023 Jul; 28(14):. doi: 10.3390/molecules28145543. [PMID: 37513415]
  • Ahmed Rakib, Mousumi Mandal, Anaum Showkat, Sonia Kiran, Soumi Mazumdar, Bhupesh Singla, Aman Bajwa, Santosh Kumar, Frank Park, Udai P Singh. Piceatannol induces regulatory T cells and modulates the inflammatory response and adipogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 May; 161(?):114514. doi: 10.1016/j.biopha.2023.114514. [PMID: 36921534]
  • Xu Yang, Yanlin Wu, Menglian Zhang, Lingyu Zhang, Tianhao Zhao, Weiwei Qian, Mengmei Zhu, Xinya Wang, Qiannuo Zhang, Jiaqiang Sun, Liuyi Dong. Piceatannol protects against age-related hearing loss by inhibiting cellular pyroptosis and inflammation through regulated Caspase11-GSDMD pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Apr; 163(?):114704. doi: 10.1016/j.biopha.2023.114704. [PMID: 37100013]
  • Nadjet Mostefa, Noureddine Djebli, Pham Ngoc Khanh, Nguyen Xuan Ha, Hoang Thi Ngoc Anh, Vu Thi Ha, Tran Thu Huong, Dang Viet Anh, Nguyen Manh Cuong. Anti-Alzheimer's Activity of Polyphenolic Stilbene-Rich Acetone Fraction of the Oil-Removed Seeds of Passiflora edulis: in Vivo and in Silico Studies. Chemistry & biodiversity. 2023 Apr; ?(?):e202201051. doi: 10.1002/cbdv.202201051. [PMID: 37032441]
  • Polina D Zlodeeva, Egor V Shekunov, Olga S Ostroumova, Svetlana S Efimova. The Degree of Hydroxylation of Phenolic Rings Determines the Ability of Flavonoids and Stilbenes to Inhibit Calcium-Mediated Membrane Fusion. Nutrients. 2023 Feb; 15(5):. doi: 10.3390/nu15051121. [PMID: 36904120]
  • Yue Wang, Qing Liu, Qiuyue Lv, Kailin Yang, Xinyan Wu, Yaping Zheng, Peigen Xiao, Baoping Jiang, Chunnian He. Investigating the chemical profile of Rheum lhasaense and its main ingredient of piceatannol-3'-O-β-D-glucopyranoside on ameliorating cognitive impairment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Feb; 160(?):114394. doi: 10.1016/j.biopha.2023.114394. [PMID: 36774724]
  • İlknur Çınar Ayan, Ebru Güçlü, Hasibe Vural, Hatice Gül Dursun. Piceatannol induces apoptotic cell death through activation of caspase-dependent pathway and upregulation of ROS-mediated mitochondrial dysfunction in pancreatic cancer cells. Molecular biology reports. 2022 Dec; 49(12):11947-11957. doi: 10.1007/s11033-022-08006-8. [PMID: 36260179]
  • Jung Yeon Kwon, Jonathan Kershaw, Chih-Yu Chen, Susan M Komanetsky, Yuyan Zhu, Xiaoxuan Guo, Phillip R Myer, Bruce Applegate, Kee-Hong Kim. Piceatannol antagonizes lipolysis by promoting autophagy-lysosome-dependent degradation of lipolytic protein clusters in adipocytes. The Journal of nutritional biochemistry. 2022 07; 105(?):108998. doi: 10.1016/j.jnutbio.2022.108998. [PMID: 35346829]
  • Flávia A R Dos Santos, Jadriane A Xavier, Felipe C da Silva, J P Jose Merlin, Marília O F Goulart, H P Vasantha Rupasinghe. Antidiabetic, Antiglycation, and Antioxidant Activities of Ethanolic Seed Extract of Passiflora edulis and Piceatannol In Vitro. Molecules (Basel, Switzerland). 2022 Jun; 27(13):. doi: 10.3390/molecules27134064. [PMID: 35807309]
  • Tingting Liu, Min Liu, He Liu, Yongfang Ren, Yanna Zhao, Hui Yan, Qingpeng Wang, Ning Zhang, Zhuang Ding, Zhengping Wang. Co-encapsulation of (-)-epigallocatechin-3-gallate and piceatannol/oxyresveratrol in β-lactoglobulin: effect of ligand-protein binding on the antioxidant activity, stability, solubility and cytotoxicity. Food & function. 2021 Aug; 12(16):7126-7144. doi: 10.1039/d1fo00481f. [PMID: 34180492]
  • Yuanyuan Huang, Jianlin Lu, Li Zhan, Ming Wang, Ronghua Shi, Xiao Yuan, Xinjiao Gao, Xing Liu, Jianye Zang, Wei Liu, Xuebiao Yao. Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism. The Journal of biological chemistry. 2021 08; 297(2):100929. doi: 10.1016/j.jbc.2021.100929. [PMID: 34216621]
  • Lingpeng Xie, Yuting Wu, Chuying Zhou, Zhangbin Tan, Honglin Xu, Guanghong Chen, Hongmei Chen, Guiqiong Huang, Huijie Fan, Lei Gao, Bin Liu, Yingchun Zhou. Piceatannol protects against sepsis-induced myocardial dysfunction via direct inhibition of JAK2. International immunopharmacology. 2021 Jul; 96(?):107639. doi: 10.1016/j.intimp.2021.107639. [PMID: 34162128]
  • Lingfeng Wang, Ying Guo, Jiayi Ye, Zeyue Pan, Peihao Hu, Xiaoming Zhong, Fengmei Qiu, Danni Zhang, Zhen Huang. Protective Effect of Piceatannol Against Cerebral Ischaemia-Reperfusion Injury Via Regulating Nrf2/HO-1 Pathway In Vivo and Vitro. Neurochemical research. 2021 Jul; 46(7):1869-1880. doi: 10.1007/s11064-021-03328-8. [PMID: 34031841]
  • Mardi M Algandaby, Majid M Al-Sawahli. Augmentation of anti-proliferative, pro-apoptotic and oxidant profiles induced by piceatannol in human breast carcinoma MCF-7 cells using zein nanostructures. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jun; 138(?):111409. doi: 10.1016/j.biopha.2021.111409. [PMID: 33684694]
  • Wanlapa Nuankaew, Armad Heemman, Chatchai Wattanapiromsakul, Ji Heon Shim, Na Woo Kim, Tamanna Yasmin, Seo Yule Jeong, Youn Hee Nam, Bin Na Hong, Sukanya Dej-Adisai, Tong Ho Kang. Anti-insulin resistance effect of constituents from Senna siamea on zebrafish model, its molecular docking, and structure-activity relationships. Journal of natural medicines. 2021 Jun; 75(3):520-531. doi: 10.1007/s11418-021-01490-5. [PMID: 33620670]
  • Minjun Xu, Kaili Hu, Yipu Liu, Yukun Huang, Shanshan Liu, Yu Chen, Dayuan Wang, Songlei Zhou, Qian Zhang, Ni Mei, Huiping Lu, Fengan Li, Xiaoling Gao, Jun Chen. Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy. Nature communications. 2021 05; 12(1):3187. doi: 10.1038/s41467-021-23466-5. [PMID: 34045459]
  • Yue Zheng, Xian-Wen Yang, Dominique Schols, Mattia Mori, Bruno Botta, Andy Chevigné, Martin Mulinge, André Steinmetz, Jean-Claude Schmit, Carole Seguin-Devaux. Active Components from Cassia abbreviata Prevent HIV-1 Entry by Distinct Mechanisms of Action. International journal of molecular sciences. 2021 May; 22(9):. doi: 10.3390/ijms22095052. [PMID: 34068829]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Enas Mahmoud Moustafa, Engy Refaat Rashed, Rasha Refaat Rashed, Nesreen Nabil Omar. Piceatannol promotes hepatic and renal AMPK/SIRT1/PGC-1α mitochondrial pathway in rats exposed to reserpine or gamma-radiation. International journal of immunopathology and pharmacology. 2021 Jan; 35(?):20587384211016194. doi: 10.1177/20587384211016194. [PMID: 33985371]
  • Hyo-Jin Kim, Jangho Lee, Min-Yu Chung, Seungpyo Hong, Jae Ho Park, Seung-Hyun Lee, Sahng Wook Park, Hyo-Kyoung Choi, Jin-Taek Hwang. Piceatannol reduces resistance to statins in hypercholesterolemia by reducing PCSK9 expression through p300 acetyltransferase inhibition. Pharmacological research. 2020 11; 161(?):105205. doi: 10.1016/j.phrs.2020.105205. [PMID: 32998069]
  • Zhongyuan Mu, Hongling Zhang, Peng Lei. Piceatannol inhibits pyroptosis and suppresses oxLDL-induced lipid storage in macrophages by regulating miR-200a/Nrf2/GSDMD axis. Bioscience reports. 2020 09; 40(9):. doi: 10.1042/bsr20201366. [PMID: 32886103]
  • Luce M Mattio, Giorgia Catinella, Andrea Pinto, Sabrina Dallavalle. Natural and nature-inspired stilbenoids as antiviral agents. European journal of medicinal chemistry. 2020 Sep; 202(?):112541. doi: 10.1016/j.ejmech.2020.112541. [PMID: 32652408]
  • Minzhuo Liu, Fen Tang, Qi Liu, Jianbo Xiao, Hui Cao, Xiaoqing Chen. Inhibition of resveratrol glucosides (REs) on advanced glycation endproducts (AGEs) formation: inhibitory mechanism and structure-activity relationship. Natural product research. 2020 Sep; 34(17):2490-2494. doi: 10.1080/14786419.2018.1538224. [PMID: 30582367]
  • Tripti Khare, Sushesh Srivatsa Palakurthi, Brijesh M Shah, Srinath Palakurthi, Sharad Khare. Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease. International journal of molecular sciences. 2020 May; 21(11):. doi: 10.3390/ijms21113956. [PMID: 32486445]
  • Xi Xu, Mengshu Zhao, Qianqian Han, Huijie Wang, Hongmei Zhang, Yanqing Wang. Effects of piceatannol on the structure and activities of bovine serum albumin: A multi-spectral and molecular modeling studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2020 Mar; 228(?):117706. doi: 10.1016/j.saa.2019.117706. [PMID: 31753657]
  • Zheng-Hong Pan, De-Sheng Ning, Yu-Xia Fu, Dian-Peng Li, Zhi-Qi Zou, Yun-Chang Xie, Ling-Ling Yu, Lian-Chun Li. Preparative Isolation of Piceatannol Derivatives from Passion Fruit (Passiflora edulis) Seeds by High-Speed Countercurrent Chromatography Combined with High-Performance Liquid Chromatography and Screening for α-Glucosidase Inhibitory Activities. Journal of agricultural and food chemistry. 2020 Feb; 68(6):1555-1562. doi: 10.1021/acs.jafc.9b04871. [PMID: 31986026]
  • Yang Cao, Wanli Smith, Liang Yan, Lingbo Kong. Overview of Cellular Mechanisms and Signaling Pathways of Piceatannol. Current stem cell research & therapy. 2020; 15(1):4-10. doi: 10.2174/1574888x14666190402100054. [PMID: 30947674]
  • Sumalee Panthong, Arunporn Itharat, Suchada Naknarin, Pranporn Kuropakornpong, Buncha Ooraikul, Intouch Sakpakdeejaroen. Bactericidal Effect and Anti-Inflammatory Activity of Cassia garettiana Heartwood Extract. TheScientificWorldJournal. 2020; 2020(?):1653180. doi: 10.1155/2020/1653180. [PMID: 32765193]
  • Min Liu, Tingting Liu, Yabo Shi, Yanna Zhao, Hui Yan, Bin Sun, Qingpeng Wang, Zhengping Wang, Jun Han. Comparative study on the interaction of oxyresveratrol and piceatannol with trypsin and lysozyme: binding ability, activity and stability. Food & function. 2019 Dec; 10(12):8182-8194. doi: 10.1039/c9fo01888c. [PMID: 31696185]
  • Sara A Wahdan, Samar S Azab, Doaa A Elsherbiny, Ebtehal El-Demerdash. Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade. Naunyn-Schmiedeberg's archives of pharmacology. 2019 11; 392(11):1331-1345. doi: 10.1007/s00210-019-01673-8. [PMID: 31197431]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Weixin Wang, Rui Yang, Huan Yao, Yun Wu, Weidong Pan, Ai-Qun Jia. Inhibiting the formation of advanced glycation end-products by three stilbenes and the identification of their adducts. Food chemistry. 2019 Oct; 295(?):10-15. doi: 10.1016/j.foodchem.2019.02.137. [PMID: 31174737]
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