Oxamate (BioDeep_00000003411)

Main id: BioDeep_00000265346

 


代谢物信息卡片


Oxalic monoamide

化学式: C2H3NO3 (89.0112928)
中文名称: 草氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=O)(C(=O)O)N
InChI: InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)

描述信息

KEIO_ID O011

同义名列表

3 个代谢物同义名

Oxalic monoamide; OXAMIC ACID; Oxamate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Haizhi Yu, Yafei Yin, Yifang Yi, Zhao Cheng, Wenyong Kuang, Ruijuan Li, Haiying Zhong, Yajuan Cui, Lingli Yuan, Fanjie Gong, Zhihua Wang, Heng Li, Hongling Peng, Guangsen Zhang. Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T-cell acute lymphoblastic leukemia. Cancer communications (London, England). 2020 10; 40(10):501-517. doi: 10.1002/cac2.12080. [PMID: 32820611]
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  • Zhimin Wang, Per Mose Nielsen, Christoffer Laustsen, Lotte Bonde Bertelsen. Metabolic consequences of lactate dehydrogenase inhibition by oxamate in hyperglycemic proximal tubular cells. Experimental cell research. 2019 05; 378(1):51-56. doi: 10.1016/j.yexcr.2019.03.001. [PMID: 30836064]
  • So-Yeon Nam, Soo-Jin Park, Dong-Soon Im. Protective effect of lodoxamide on hepatic steatosis through GPR35. Cellular signalling. 2019 01; 53(?):190-200. doi: 10.1016/j.cellsig.2018.10.001. [PMID: 30304698]
  • Mu-Chao Wu, Wei-Ran Ye, Yi-Jia Zheng, Shan-Shan Zhang. Oxamate Enhances the Anti-Inflammatory and Insulin-Sensitizing Effects of Metformin in Diabetic Mice. Pharmacology. 2017; 100(5-6):218-228. doi: 10.1159/000478909. [PMID: 28728159]
  • Weiran Ye, Yijia Zheng, Shanshan Zhang, Li Yan, Hua Cheng, Muchao Wu. Oxamate Improves Glycemic Control and Insulin Sensitivity via Inhibition of Tissue Lactate Production in db/db Mice. PloS one. 2016; 11(3):e0150303. doi: 10.1371/journal.pone.0150303. [PMID: 26938239]
  • Yang Wang, Lian Wei, Lin-na Wei, Xiao Li, Li-na Xu, Deng-bang Wei. [Establishment of RP-HPLC detection method of N-isopropyl oxamate in the serum of plateau pikas]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 2015 Sep; 31(5):469-72, 476. doi: . [PMID: 26827545]
  • Kang Zheng, Ling Zhu, Yan-Tuan Li, Zhi-Yong Wu, Cui-Wei Yan. Synthesis and crystal structure of new dicopper(II) complexes having asymmetric N,N'-bis(substituted)oxamides with DNA/protein binding ability: In vitro anticancer activity and molecular docking studies. Journal of photochemistry and photobiology. B, Biology. 2015 Aug; 149(?):129-42. doi: 10.1016/j.jphotobiol.2015.05.014. [PMID: 26057022]
  • Feng-Jia Zhao, Hong-Qin Zhao, Fang Liu, Yan-Tuan Li, Zhi-Yong Wu, Cui-Wei Yan. Synthesis and crystal structure of new dicopper(II) complexes with N,N'-bis-(dipropylenetriamine)oxamide as bridging ligand: effects of the counterions on DNA/protein-binding property and in vitro antitumor activity. Journal of photochemistry and photobiology. B, Biology. 2015 Feb; 143(?):148-62. doi: 10.1016/j.jphotobiol.2014.12.030. [PMID: 25635907]
  • Jing Jiao, Man Jiang, Yan-Tuan Li, Zhi-Yong Wu, Cui-Wei Yan. In vitro cytotoxic activities, DNA-, and BSA-binding studies of a new dinuclear copper(II) complex with N-[3-(dimethylamino)propyl]-N'-(2-carboxylatophenyl)-oxamide as ligand. Journal of biochemical and molecular toxicology. 2014 Feb; 28(2):47-59. doi: 10.1002/jbt.21535. [PMID: 24497175]
  • Chie Hashimoto, Tetsuo Narumi, Hiroyuki Otsuki, Yuki Hirota, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Nami Ohashi, Wataru Nomura, Tomoyuki Miura, Tatsuhiko Igarashi, Shuzo Matsushita, Hirokazu Tamamura. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorganic & medicinal chemistry. 2013 Dec; 21(24):7884-9. doi: 10.1016/j.bmc.2013.10.005. [PMID: 24189188]
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  • Xiao-Wen Li, Xue-Jie Li, Yan-Tuan Li, Zhi-Yong Wu, Cui-Wei Yan. Syntheses and structures of new trimetallic complexes bridged by N-(5-chloro-2-hydroxyphenyl)-N'-[3-(dimethylamino)propyl]oxamide: cytotoxic activities, and reactivities towards DNA and protein. Journal of photochemistry and photobiology. B, Biology. 2013 Jan; 118(?):22-32. doi: 10.1016/j.jphotobiol.2012.10.009. [PMID: 23186805]
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