Carbazole (BioDeep_00000003365)
Secondary id: BioDeep_00001867695
human metabolite blood metabolite
代谢物信息卡片
Dibenzo(b,D)pyrrole
化学式: C12H9N (167.0735)
中文名称: 咔唑
谱图信息:
最多检出来源 Homo sapiens(blood) 20.72%
分子结构信息
SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2
InChI: InChI=1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H
描述信息
CONFIDENCE standard compound; INTERNAL_ID 1
D009676 - Noxae > D002273 - Carcinogens
KEIO_ID C040
同义名列表
数据库引用编号
33 个数据库交叉引用编号
- ChEBI: CHEBI:27543
- KEGG: C08060
- PubChem: 6854
- HMDB: HMDB0249614
- Metlin: METLIN66794
- DrugBank: DB07301
- ChEMBL: CHEMBL243580
- Wikipedia: Carbazole
- MetaCyc: CPD-12475
- KNApSAcK: C00024693
- chemspider: 6593
- CAS: 51555-21-6
- CAS: 86-74-8
- MoNA: KO000450
- MoNA: KO000448
- MoNA: KO000449
- MoNA: KO000446
- MoNA: KO002556
- MoNA: KO000447
- MoNA: KO002555
- MoNA: UA000103
- MoNA: UA000101
- MoNA: KO002552
- MoNA: KO002554
- MoNA: KO002553
- PMhub: MS000009546
- PubChem: 10260
- PDB-CCD: 9CA
- 3DMET: B01106
- NIKKAJI: J3.896B
- LOTUS: LTS0037890
- wikidata: Q424003
- KNApSAcK: 27543
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- carbazole degradation:
2'-aminobiphenyl-2,3-diol + O2 ⟶ (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H+
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 159045 - Glycosmis mauritiana: 10.1016/S0031-9422(00)81785-9
- 76967 - Glycosmis pentaphylla: 10.1016/S0031-9422(00)81785-9
- 9606 - Homo sapiens: -
- 159030 - Murraya koenigii:
- 1883 - Streptomyces: 10.1002/ANIE.201906864
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shiv Nandan, Sumit K Singh, Pratibha Singh, Vikas Bajpai, Ashwanee K Mishra, Trapti Joshi, Rohit Mahar, Sanjeev K Shukla, Dipak K Mishra, Sanjeev Kanojiya. Quantitative Analysis of Bioactive Carbazole Alkaloids in Murraya koenigii (L.) from Six Different Climatic Zones of India Using UPLC/MS/MS and Their Principal Component Analysis.
Chemistry & biodiversity.
2021 Dec; 18(12):e2100557. doi:
10.1002/cbdv.202100557. [PMID: 34643999] - Speranta Avram, Ana Maria Udrea, Diana Camelia Nuta, Carmen Limban, Adrian Cosmin Balea, Miron Teodor Caproiu, Florea Dumitrascu, Cătălin Buiu, Alexandra Teodora Bordei. Synthesis and Bioinformatic Characterization of New Schiff Bases with Possible Applicability in Brain Disorders.
Molecules (Basel, Switzerland).
2021 Jul; 26(14):. doi:
10.3390/molecules26144160. [PMID: 34299440] - Yan-Ping Liu, Yu-Jie Li, Ying-Ying Zhao, Jia-Ming Guo, Yun-Yao Liu, Xiao-Ping Wang, Zhang-Yang Shen, Lei Qiang, Yan-Hui Fu. Carbazole alkaloids from the fruits of Clausena anisum-olens with potential PTP1B and α-glucosidase inhibitory activities.
Bioorganic chemistry.
2021 05; 110(?):104775. doi:
10.1016/j.bioorg.2021.104775. [PMID: 33725509] - Faisal Rashid, Sumera Zaib, Aliya Ibrar, Syeda A Ejaz, Aamer Saeed, Jamshed Iqbal, Imtiaz Khan. New Hybrid Scaffolds Based on Carbazole-Chalcones as Potent Anticancer Agents.
Anti-cancer agents in medicinal chemistry.
2021; 21(9):1082-1091. doi:
10.2174/1871520620666200721110732. [PMID: 32698741] - Satoshi Yamashita, Ryo Honda, Mayuko Fukuoka, Tsutomu Kimura, Junji Hosokawa-Muto, Kazuo Kuwata. Discovery of a multipotent chaperone, 1-(2,6-Difluorobenzylamino)-3-(1,2,3,4-tetrahydrocarbazol-9-yl)-propan-2-ol with the inhibitory effects on the proliferation of prion, cancer as well as influenza virus.
Prion.
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Nature chemical biology.
2020 04; 16(4):383-386. doi:
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Journal of natural medicines.
2020 Mar; 74(2):448-455. doi:
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Phytochemistry.
2020 Feb; 170(?):112186. doi:
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2019 11; 92(?):103278. doi:
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Bioorganic chemistry.
2019 10; 91(?):103107. doi:
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2019 Sep; 17(9):663-671. doi:
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2019 Jul; 67(26):7512-7525. doi:
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2019 May; 67(20):5764-5771. doi:
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2018 04; 77(?):387-392. doi:
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2017 Dec; 15(12):881-888. doi:
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2017 10; 27(19):4564-4570. doi:
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2017 09; 27(18):4294-4297. doi:
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2015 Jun; 103(?):122-8. doi:
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2014 Apr; 94(?):10-20. doi:
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2013 Jul; 10(7):1317-21. doi:
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Fitoterapia.
2010 Dec; 81(8):1129-33. doi:
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Physical chemistry chemical physics : PCCP.
2010 May; 12(17):4360-6. doi:
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Phytotherapy research : PTR.
2010 Apr; 24(4):629-31. doi:
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Philosophical transactions. Series A, Mathematical, physical, and engineering sciences.
2010 Mar; 368(1914):1027-82. doi:
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Molecular and cellular biochemistry.
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Journal of biomedical science.
2010 Feb; 17(?):8. doi:
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Fitoterapia.
2010 Jan; 81(1):72-4. doi:
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PloS one.
2009 Dec; 4(12):e8439. doi:
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Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
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European journal of medicinal chemistry.
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BMC evolutionary biology.
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Chemical & pharmaceutical bulletin.
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International journal of occupational medicine and environmental health.
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Biochemical and biophysical research communications.
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Chinese medicine.
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Scandinavian journal of urology and nephrology.
2007; 41(3):218-22. doi:
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Environmental toxicology and chemistry.
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The Prostate.
2006 Sep; 66(12):1257-65. doi:
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Environmental health perspectives.
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Biophysical chemistry.
2006 Feb; 119(3):307-15. doi:
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Phytotherapy research : PTR.
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2005 Aug; 60(8):637-9. doi:
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Biochemistry.
2005 Jul; 44(28):9703-13. doi:
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Bioorganic & medicinal chemistry.
2005 Jul; 13(13):4279-90. doi:
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Phytochemistry.
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Journal of medicinal chemistry.
2005 Apr; 48(7):2282-93. doi:
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Phytochemistry.
2005 Mar; 66(6):697-701. doi:
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Planta medica.
2005 Mar; 71(3):261-7. doi:
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Chemical & pharmaceutical bulletin.
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2004 Sep; 67(9):1488-91. doi:
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Organic letters.
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