Classification Term: 286
Carbazoles (ontology term: CHEMONTID:0000210)
Compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring." []
found 83 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Indoles and derivatives
Child Taxonomies: Pyrrolocarbazoles, N-acylcarbazoles
Elliptisine
Ellipticine is a organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11. It has a role as an antineoplastic agent and a plant metabolite. It is an organic heterotetracyclic compound, an organonitrogen heterocyclic compound, a polycyclic heteroarene and an indole alkaloid. Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.
Carvedilol
Carvedilol is only found in individuals that have used or taken this drug. It is a non-selective beta blocker indicated in the treatment of mild to moderate congestive heart failure (CHF).Carvedilol is a racemic mixture in which nonselective beta-adrenoreceptor blocking activity is present in the S(-) enantiomer and alpha-adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilols beta-adrenergic receptor blocking ability decreases the heart rate, myocardial contractility, and myocardial oxygen demand. Carvedilol also decreases systemic vascular resistance via its alpha adrenergic receptor blocking properties. Carvedilol and its metabolite BM-910228 (a less potent beta blocker, but more potent antioxidant) have been shown to restore the inotropic responsiveness to Ca2+ in OH- free radical-treated myocardium. Carvedilol and its metabolites also prevent OH- radical-induced decrease in sarcoplasmic reticulum Ca2+-ATPase activity. Therefore, carvedilol and its metabolites may be beneficial in chronic heart failure by preventing free radical damage. C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AG - Alpha and beta blocking agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D020011 - Protective Agents > D000975 - Antioxidants D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3].
Carprofen
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild, such as gastro-intestinal pain and nausea, similar to those recorded with aspirin and other non-steroidal anti-inflammatory drugs. It is no longer marketed for human usage, after being withdrawn on commercial grounds. [Wikipedia] C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents D003879 - Dermatologic Agents Carprofen is a nonsteroid anti-inflammatory agent, acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 μM, 22.3 μM and 78.6 μM for COX-2, COX-1 and FAAH, respectively.
Ondansetron
Ondansetron is a well tolerated drug with few side effects. Headache, constipation, and dizziness are the most commonly reported side effects associated with its use. There have been no significant drug interactions reported with this drugs use. It is broken down by the hepatic cytochrome P450 system and it has little effect on the metabolism of other drugs broken down by this system; Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly to treat nausea and vomiting following chemotherapy. Its effects are thought to be on both peripheral and central nerves. One part is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata, the other is a blockage of serotonin receptors in the chemoreceptor trigger zone. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors; A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties; Ondansetron (INN) is a serotonin 5-HT3 receptor antagonist used mainly to treat nausea and vomiting following chemotherapy. Its effects are thought to be on both peripheral and central nerves. One part is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata, the other is a blockage of serotonin receptors in the chemoreceptor trigger zone. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors. [HMDB] Ondansetron is a well tolerated drug with few side effects. Headache, constipation, and dizziness are the most commonly reported side effects associated with its use. There have been no significant drug interactions reported with this drugs use. It is broken down by the hepatic cytochrome P450 system and it has little effect on the metabolism of other drugs broken down by this system; Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly to treat nausea and vomiting following chemotherapy. Its effects are thought to be on both peripheral and central nerves. One part is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata, the other is a blockage of serotonin receptors in the chemoreceptor trigger zone. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors; A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties; Ondansetron (INN) is a serotonin 5-HT3 receptor antagonist used mainly to treat nausea and vomiting following chemotherapy. Its effects are thought to be on both peripheral and central nerves. One part is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata, the other is a blockage of serotonin receptors in the chemoreceptor trigger zone. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors. A - Alimentary tract and metabolism > A04 - Antiemetics and antinauseants > A04A - Antiemetics and antinauseants > A04AA - Serotonin (5ht3) antagonists C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist > C94726 - 5-HT3 Receptor Antagonist D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D003879 - Dermatologic Agents > D000982 - Antipruritics CONFIDENCE standard compound; INTERNAL_ID 2746 CONFIDENCE standard compound; INTERNAL_ID 8525 D002491 - Central Nervous System Agents Ondansetron (GR 38032; SN 307) is a highly selective 5-HT3 receptor antagonist, with IC50 value of 103 pM. Ondansetron exerts antiemetic effects by antagonizing 5-HT receptor located on local neurons in the peripheral and central nervous system. Ondansetron suppresses nausea and vomiting caused by chemotherapy and radiation therapy. Ondansetron has orally bioactivity[1][2][3][4][5][6][7][8].
Carbazole
CONFIDENCE standard compound; INTERNAL_ID 1 D009676 - Noxae > D002273 - Carcinogens KEIO_ID C040
(+)-Mahanimbine
(±)-Mahanimbine is found in herbs and spices. (±)-Mahanimbine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree Alkaloid from the stem bark of Murraya koenigii (curryleaf tree). (±)-Mahanimbine is found in herbs and spices.
Murrayanine
Murrayanine is found in herbs and spices. Murrayanine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Murrayanine is found in herbs and spices.
Fumitremorgin B
C27H33N3O5 (479.24200880000006)
Fumitremorgin B is a mycotoxin produced by Aspergillus fumigatus, Aspergillus caespitosus, Penicillium lanosum and Penicillium piscarium. Fumitremorgin B is isolated from A. fumigatus infected rice and mis
Pyrafoline D
3,8-Dimethyl-3-(4-methylpent-3-en-1-yl)-3,11-dihydropyrano[3,2-a]carbazol-9-ol is a natural product found in Murraya euchrestifolia, Murraya koenigii, and Murraya kwangsiensis with data available. Pyrafoline D is found in herbs and spices. Pyrafoline D is an alkaloid from seeds of Murraya koenigii (curryleaf tree). Alkaloid from seeds of Murraya koenigii (curryleaf tree). Pyrafoline D is found in herbs and spices.
(+)-Mahanimbicine
(+)-Mahanimbicine is found in herbs and spices. (+)-Mahanimbicine is an alkaloid from the leaves of Murraya koenigii (curryleaf tree (+)-Mahanimbicine is a member of carbazoles. (+)-Mahanimbicine is a natural product found in Murraya koenigii with data available.
Girinimbine
Girinimbine is a member of carbazoles. It has a role as a metabolite. Girinimbine is a natural product found in Clausena vestita, Murraya euchrestifolia, and other organisms with data available. Girinimbine is found in herbs and spices. Girinimbine is an alkaloid from the roots of Murraya koenigii (curry leaf tree A natural product found in Clausena harmandiana.
Heptaphylline
Heptaphylline is found in fruits. Heptaphylline is an alkaloid from the leaves of Clausena lansium (wampee
(R)-Mahanine
(R)-Mahanine is found in herbs and spices. (R)-Mahanine is an alkaloid from the leaves of Murraya koenigii (curry leaf tree). Alkaloid from the leaves of Murraya koenigii (curry leaf tree). (R)-Mahanine is found in herbs and spices.
Koenine
Koenine is found in herbs and spices. Koenine is an alkaloid from the leaves of Murraya koenigii (curryleaf tree
Murrastifoline F
C28H24N2O2 (420.18376839999996)
Murrastifoline F is found in herbs and spices. Murrastifoline F is an alkaloid from roots of Murraya koenigii (curryleaf tree). Alkaloid from roots of Murraya koenigii (curryleaf tree). Murrastifoline F is found in herbs and spices.
Bismurrayafoline E
Bismurrayafoline E is found in herbs and spices. Bismurrayafoline E is an alkaloid from the leaves of Murraya koenigii (curryleaf tree). Alkaloid from the leaves of Murraya koenigii (curryleaf tree). Bismurrayafoline E is found in herbs and spices.
Mukolidine
Mukolidine is found in herbs and spices. Minor alkaloid from roots of Murraya koenigii (curryleaf tree). Minor alkaloid from roots of Murraya koenigii (curryleaf tree). Mukolidine is found in herbs and spices.
Mukoenine B
Mukoenine B is found in herbs and spices. Mukoenine B is an alkaloid from Murraya koenigii (curryleaf tree). Alkaloid from Murraya koenigii (curryleaf tree). Mukoenine B is found in herbs and spices.
Koeniginequinone A
Koeniginequinone A is found in herbs and spices. Koeniginequinone A is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
1-Hydroxy-3-methyl-9H-carbazole
1-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices. 1-Hydroxy-3-methyl-9H-carbazole is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Alkaloid from the stem bark of Murraya koenigii (curryleaf tree). 1-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices.
2-Hydroxy-3-methyl-9H-carbazole
2-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices. 2-Hydroxy-3-methyl-9H-carbazole is an alkaloid from the roots of Murraya koenigii (curryleaf tree). Alkaloid from the roots of Murraya koenigii (curryleaf tree). 2-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices.
Koenoline
C14H13NO2 (227.09462380000002)
Koenoline is found in herbs and spices. Koenoline is an alkaloid from the root bark of Murraya koenigii (curryleaf tree). Alkaloid from the root bark of Murraya koenigii (curryleaf tree). Koenoline is found in herbs and spices.
Currayanine
Currayanine is found in herbs and spices. Currayanine is an alkaloid from the leaves and stem bark of Murraya koenigii (curryleaf tree
Murrayacinine
Murrayacinine is found in herbs and spices. Murrayacinine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
Murrayamine A
Murrayamine A is found in herbs and spices. Murrayamine A is an alkaloid from the roots of Murraya koenigii (curryleaf tree). Alkaloid from the roots of Murraya koenigii (curryleaf tree). Murrayamine A is found in herbs and spices.
Koeniginequinone B
Koeniginequinone B is found in herbs and spices. Koeniginequinone B is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
Murrayacine
Murrayacine is found in herbs and spices. Murrayacine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Murrayacine is found in herbs and spices.
Bicyclomahanimbine
Bicyclomahanimbine is found in herbs and spices. Bicyclomahanimbine is an alkaloid from the leaves of Murraya koenigii (curryleaf tree
Mukonicine
C20H21NO3 (323.15213560000007)
Mukonicine is found in herbs and spices. Mukonicine is an alkaloid from the leaves of Murraya koenigii (curry leaf tree
Bismahanine
Bismahanine is found in herbs and spices. Bismahanine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Bismahanine is found in herbs and spices.
Clausine L
Clausine L is found in herbs and spices. Clausine L is an alkaloid from stem bark of Murraya koenigii (curryleaf tree
Mahanimbinol
Mahanimbinol is found in herbs and spices. Mahanimbinol is an alkaloid from Murraya koenigii (curryleaf tree). Alkaloid from Murraya koenigii (curryleaf tree). Mahanimbinol is found in herbs and spices.
Methyl 6-methoxy-9H-carbazole-3-carboxylate
Methyl 6-methoxy-9H-carbazole-3-carboxylate is found in fruits. Methyl 6-methoxy-9H-carbazole-3-carboxylate is an alkaloid from the roots of Clausena lansium (wampee). Alkaloid from the roots of Clausena lansium (wampee). Methyl 6-methoxy-9H-carbazole-3-carboxylate is found in fruits.
2-Methoxy-3-methyl-9H-carbazole
2-Methoxy-3-methyl-9H-carbazole is found in herbs and spices. 2-Methoxy-3-methyl-9H-carbazole is an alkaloid from the seeds of Murraya koenigii (curryleaf tree). Alkaloid from the seeds of Murraya koenigii (curryleaf tree). 2-Methoxy-3-methyl-9H-carbazole is found in herbs and spices.
1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde
1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde is found in fruits. 1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde is an alkaloid from the roots of Clausena lansium (wampee). Alkaloid from the roots of Clausena lansium (wampee). 1,6-Dimethoxy-9H-carbazole-3-carboxaldehyde is found in fruits.
Bikoeniquinone A
Bikoeniquinone A is found in herbs and spices. Bikoeniquinone A is an alkaloid from roots of Murraya koenigii (curryleaf tree) (Rutaceae). Alkaloid from roots of Murraya koenigii (curryleaf tree) (Rutaceae). Bikoeniquinone A is found in herbs and spices.
7-Hydroxyheptaphylline
7-Hydroxyheptaphylline is found in fruits. 7-Hydroxyheptaphylline is an alkaloid from root bark of Clausena lansium (wampee). Alkaloid from root bark of Clausena lansium (wampee). 7-Hydroxyheptaphylline is found in fruits.
Bicyclomahanimbicine
Bicyclomahanimbicine is found in herbs and spices. Bicyclomahanimbicine is an alkaloid from the leaves of Murraya koenigii (curryleaf tree
Ethyl 3-methyl-9H-carbazole-9-carboxylate
Ethyl 3-methyl-9H-carbazole-9-carboxylate is found in herbs and spices. Ethyl 3-methyl-9H-carbazole-9-carboxylate is an alkaloid from the roots of Murraya koenigii (curryleaf tree). Alkaloid from the roots of Murraya koenigii (curryleaf tree). Ethyl 3-methyl-9H-carbazole-9-carboxylate is found in herbs and spices.
1,1'-Bis(2-hydroxy-3-methylcarbazole)
1,1-Bis(2-hydroxy-3-methylcarbazole) is found in herbs and spices. 1,1-Bis(2-hydroxy-3-methylcarbazole) is an alkaloid from roots of Murraya koenigii (curryleaf tree). Alkaloid from roots of Murraya koenigii (curryleaf tree). 1,1-Bis(2-hydroxy-3-methylcarbazole) is found in herbs and spices.
Koenigine
C19H19NO3 (309.13648639999997)
Koenigine is found in herbs and spices. Koenigine is an alkaloid from the leaves of Murraya koenigii (curryleaf tree
6-Methoxy-9H-carbazole-3-carboxaldehyde
6-Methoxy-9H-carbazole-3-carboxaldehyde is found in fruits. 6-Methoxy-9H-carbazole-3-carboxaldehyde is an alkaloid from the roots of Clausena lansium (wampee). Alkaloid from the roots of Clausena lansium (wampee). 6-Methoxy-9H-carbazole-3-carboxaldehyde is found in fruits.
Lansine
Lansine is found in fruits. Lansine is an alkaloid from the leaves of Clausena lansium (wampee
Mukonine
Mukonine is found in herbs and spices. Mukonine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
Launobine
C18H17NO4 (311.11575220000003)
Launobine is found in herbs and spices. Launobine is an alkaloid from Laurus nobilis (bay laurel
Koenimbine
Koenimbine is found in herbs and spices. Koenimbine is an alkaloid from leaves and fruits of Murraya koenigii (curryleaf tree
Mukonal
Mukonal is found in herbs and spices. Mukonal is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
9H-Carbazole-3-carboxaldehyde
9H-Carbazole-3-carboxaldehyde is found in fruits. 9H-Carbazole-3-carboxaldehyde is an alkaloid from the roots of Clausena lansium (wampee
Mahanimbinine
Mahanimbinine is found in herbs and spices. Mahanimbinine is an alkaloid from leaves of Murraya koenigii (curryleaf tree
Murrayanol
Murrayanol is found in herbs and spices. Murrayanol is an alkaloid from seeds of Murraya koenigii (curry leaf tree). Alkaloid from seeds of Murraya koenigii (curry leaf tree). Murrayanol is found in herbs and spices.
Methyl 3-carbazolecarboxylate
Methyl 3-carbazolecarboxylate is found in fruits. Methyl 3-carbazolecarboxylate is an alkaloid from the roots of Clausena lansium (wampee
Mukoenine A
Mukoenine A is found in herbs and spices. Mukoenine A is an alkaloid from stem bark and roots of Murraya koenigii (curryleaf tree). Alkaloid from stem bark and roots of Murraya koenigii (curryleaf tree). Mukoenine A is found in herbs and spices.
Bismurrayaquinone A
Bismurrayaquinone A is found in herbs and spices. Bismurrayaquinone A is an alkaloid from roots of Murraya koenigii (curryleaf tree). Alkaloid from roots of Murraya koenigii (curryleaf tree). Bismurrayaquinone A is found in herbs and spices.
Koenigicine
C20H21NO3 (323.15213560000007)
Koenigicine is found in herbs and spices. Koenigicine is an alkaloid from the leaves of Murraya koenigii (curryleaf tree
Mukonidine
Mukonidine is found in herbs and spices. Mukonidine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
O-Desmethylcarvedilol
O-Desmethylcarvedilol is only found in individuals that have used or taken Carvedilol. O-Desmethylcarvedilol is a metabolite of Carvedilol. O-desmethylcarvedilol belongs to the family of Carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
Mukoline
C14H13NO2 (227.09462380000002)
Mukoline is found in herbs and spices. Minor alkaloid from roots of Murraya koenigii (curryleaf tree). Minor alkaloid from roots of Murraya koenigii (curryleaf tree). Mukoline is found in herbs and spices.
8-Hydroxycarvedilol
C24H26N2O5 (422.18416260000004)
8-Hydroxycarvedilol is only found in individuals that have used or taken Carvedilol. 8-Hydroxycarvedilol is a metabolite of Carvedilol. 8-hydroxycarvedilol belongs to the family of Carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
4'-Hydroxycarvedilol
C24H26N2O5 (422.18416260000004)
4-Hydroxycarvedilol is only found in individuals that have used or taken Carvedilol. 4-Hydroxycarvedilol is a metabolite of Carvedilol. 4-hydroxycarvedilol belongs to the family of Carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
5'-Hydroxycarvedilol
C24H26N2O5 (422.18416260000004)
5-Hydroxycarvedilol is only found in individuals that have used or taken Carvedilol. 5-Hydroxycarvedilol is a metabolite of Carvedilol. 5-hydroxycarvedilol belongs to the family of Carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
1-Hydroxycarvedilol
C24H26N2O5 (422.18416260000004)
1-Hydroxycarvedilol is only found in individuals that have used or taken Carvedilol. 1-Hydroxycarvedilol is a metabolite of Carvedilol. 1-hydroxycarvedilol belongs to the family of Carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
Frovatriptan
Frovatriptan, also known as Frova (trade name), belongs to a class of medications known as 5-hydroxytryptamine agonists (triptan) (PMID: 18001261). It is widely indicated for the treatment of migraine headaches with or without aura in adults (PMID: 22900951, 27103792). It works in the brain to relieve migraine symptoms including headache, pain, nausea, vomiting, sensitivity to light/sound. However, it is not used to treat patients with hemiplegic, ophthalmoplegic or basilar migraine. Frovatriptan binds with high affinity for serotonin 5-HT1B and 5-HT1D receptors, thereby relieving pain by narrowing blood vessels (PMID: 11735616, 12517245). Patient’s may experience some side effects, especially who have heart or blood vessel disease. Frovatriptan is only found in individuals who have consumed or used this drug. N - Nervous system > N02 - Analgesics > N02C - Antimigraine preparations > N02CC - Selective serotonin (5ht1) agonists D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist
Mukeic acid
Mukeic acid is found in herbs and spices. Mukeic acid is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
Hydroxyl frovatriptan
C14H19N3O2 (261.14771939999997)
Hydroxyl frovatriptan is a metabolite of frovatriptan. Frovatriptan (trade name Frova) is a triptan drug developed by Vernalis for the treatment of migraine headaches and for short term prevention of menstrual migraine. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe. (Wikipedia)
Hydroxylated N-acetyl desmethyl frovatriptan
Hydroxylated N-acetyl desmethyl frovatriptan is a metabolite of frovatriptan. Frovatriptan (trade name Frova) is a triptan drug developed by Vernalis for the treatment of migraine headaches and for short term prevention of menstrual migraine. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe. (Wikipedia)
N-Acetyl desmethyl frovatriptan
C15H19N3O2 (273.14771939999997)
N-Acetyl desmethyl frovatriptan is a metabolite of frovatriptan. Frovatriptan (trade name Frova) is a triptan drug developed by Vernalis for the treatment of migraine headaches and for short term prevention of menstrual migraine. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe. (Wikipedia)
2-[6,8-Difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid
C22H21F2NO4S (433.11592900000005)
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
C26170 - Protective Agent > C1509 - Neuroprotective Agent Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease[1][2].
8-Hydroxyondansetron
C18H19N3O2 (309.14771939999997)
9-Hydroxyellipticine
D000970 - Antineoplastic Agents > D000972 - Antineoplastic Agents, Phytogenic > D004611 - Ellipticines D009676 - Noxae > D000963 - Antimetabolites
9-Methoxyellipticine
D000970 - Antineoplastic Agents > D000972 - Antineoplastic Agents, Phytogenic > D004611 - Ellipticines
Alectinib
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01ED - Anaplastic lymphoma kinase (alk) inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C141136 - ALK Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
(R)-3-[3-(4-Fluorophenylsulphonylamino)-1,2,3,4-tetrahydrocarbazol-9-yl]propionic acid
C21H21FN2O4S (416.12059980000004)
Carazolol
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists Carazolol is a β1/β2 adrenoceptor antagonist of high potency used in the research of hypertension. Carazolol is also a potent, selective β3-adrenoceptor agonist[1].
Fluorocarazolol
C18H21FN2O2 (316.15869779999997)
N-[(6R)-6-(Dimethylamino)-6,7,8,9-tetrahydro-5H-carbazol-3-yl]-4-fluorobenzamide
Malagashanine
Pirlindole
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors C471 - Enzyme Inhibitor > C667 - Monoamine Oxidase Inhibitor D000970 - Antineoplastic Agents
Melonin
Melonin is a member of the class of compounds known as carbazoles. Carbazoles are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring. Melonin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Melonin can be found in muskmelon, which makes melonin a potential biomarker for the consumption of this food product.
Plantacyanin
Isolated from cucumber. Plantacyanin is found in green vegetables.