Sekisanin (BioDeep_00000002770)

   


代谢物信息卡片


8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)-

化学式: C18H21NO5 (331.142)
中文名称: 多花水仙碱
谱图信息: 最多检出来源 not specific(not specific) 0%

分子结构信息

SMILES: CN1CC2(C3(C1CC(C=C3)OC)C4=CC5=C(C=C4CO2)OCO5)O
InChI: InChI=1S/C18H21NO5/c1-19-9-18(20)17(4-3-12(21-2)6-16(17)19)13-7-15-14(22-10-23-15)5-11(13)8-24-18/h3-5,7,12,16,20H,6,8-10H2,1-2H3



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ABCB1, AKR1C3, ANXA5, BCL2L1, HDAC2
Peripheral membrane protein 2 ACHE, ANXA5
Endosome membrane 1 SLC6A4
Mitochondrion membrane 1 BCL2L1
Nucleus 5 ACHE, AKR1C3, AURKA, HDAC2, KDR
cytosol 4 AKR1C3, ANXA5, AURKA, BCL2L1
centrosome 2 AURKA, BCL2L1
nucleoplasm 2 AURKA, HDAC2
Cell membrane 4 ABCB1, ACHE, KDR, SLC6A4
Cytoplasmic side 1 BCL2L1
Multi-pass membrane protein 2 ABCB1, SLC6A4
Synapse 2 ACHE, SLC6A4
cell junction 1 KDR
cell surface 2 ABCB1, ACHE
glutamatergic synapse 1 AURKA
Golgi apparatus 2 ACHE, KDR
mitochondrial inner membrane 1 BCL2L1
neuromuscular junction 1 ACHE
presynaptic membrane 1 SLC6A4
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 BCL2L1
Presynapse 1 SLC6A4
endosome 1 KDR
plasma membrane 5 ABCB1, ACHE, BCHE, KDR, SLC6A4
synaptic vesicle membrane 1 BCL2L1
Membrane 5 ABCB1, ACHE, ANXA5, HDAC2, SLC6A4
apical plasma membrane 1 ABCB1
axon 1 CCK
basolateral plasma membrane 1 AURKA
extracellular exosome 3 ABCB1, AKR1C3, ANXA5
endoplasmic reticulum 2 BCL2L1, KDR
extracellular space 3 ACHE, BCHE, CCK
perinuclear region of cytoplasm 2 ACHE, AURKA
mitochondrion 1 BCL2L1
protein-containing complex 1 HDAC2
postsynaptic density 1 AURKA
ESC/E(Z) complex 1 HDAC2
pronucleus 1 AURKA
Secreted 3 ACHE, BCHE, CCK
extracellular region 5 ACHE, ANXA5, BCHE, CCK, KDR
Mitochondrion outer membrane 1 BCL2L1
Single-pass membrane protein 1 BCL2L1
mitochondrial outer membrane 1 BCL2L1
[Isoform 2]: Secreted 1 KDR
Mitochondrion matrix 1 BCL2L1
mitochondrial matrix 1 BCL2L1
Extracellular side 1 ACHE
anchoring junction 1 KDR
Cell projection, cilium 1 AURKA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 2 AURKA, BCL2L1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 BCL2L1
Nucleus membrane 1 BCL2L1
Bcl-2 family protein complex 1 BCL2L1
nuclear membrane 1 BCL2L1
external side of plasma membrane 2 ANXA5, KDR
microtubule cytoskeleton 1 AURKA
midbody 1 AURKA
Early endosome 1 KDR
spindle midzone 1 AURKA
postsynaptic membrane 1 SLC6A4
Apical cell membrane 1 ABCB1
Membrane raft 2 KDR, SLC6A4
Cell junction, focal adhesion 1 SLC6A4
Cytoplasm, cytoskeleton, spindle 1 AURKA
focal adhesion 2 ANXA5, SLC6A4
microtubule 1 AURKA
spindle 1 AURKA
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 ANXA5
receptor complex 1 KDR
Cell projection, neuron projection 2 AURKA, SLC6A4
Zymogen granule membrane 1 ANXA5
neuron projection 2 AURKA, SLC6A4
ciliary basal body 1 AURKA
cilium 1 AURKA
chromatin 1 HDAC2
mitotic spindle 1 AURKA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 AURKA
Cytoplasm, cytoskeleton, cilium basal body 1 AURKA
centriole 1 AURKA
chromosome, telomeric region 1 HDAC2
blood microparticle 1 BCHE
Basolateral cell membrane 1 AURKA
Lipid-anchor, GPI-anchor 1 ACHE
Cytoplasm, cytoskeleton, spindle pole 1 AURKA
Endomembrane system 1 SLC6A4
sorting endosome 1 KDR
side of membrane 1 ACHE
endoplasmic reticulum lumen 1 BCHE
kinetochore 1 AURKA
histone deacetylase complex 1 HDAC2
mitotic spindle pole 1 AURKA
NuRD complex 1 HDAC2
nuclear envelope lumen 1 BCHE
vesicle membrane 1 ANXA5
axon hillock 1 AURKA
chromosome passenger complex 1 AURKA
germinal vesicle 1 AURKA
meiotic spindle 1 AURKA
spindle pole centrosome 1 AURKA
synaptic cleft 1 ACHE
Sin3-type complex 1 HDAC2
external side of apical plasma membrane 1 ABCB1
endothelial microparticle 1 ANXA5
[Isoform H]: Cell membrane 1 ACHE
serotonergic synapse 1 SLC6A4
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • Daniel Zaragoza-Puchol, Javier E Ortiz, Alejandro A Orden, Marianela Sanchez, Jorge Palermo, Alejandro Tapia, Jaume Bastida, Gabriela E Feresin. Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies. Molecules (Basel, Switzerland). 2021 Jan; 26(1):. doi: 10.3390/molecules26010192. [PMID: 33401696]
  • Ameneh Tarakemeh, Majid Azizi, Vahid Rowshan, Hassan Salehi, Rosella Spina, François Dupire, Hossein Arouie, Dominique Laurain-Mattar. Screening of Amaryllidaceae alkaloids in bulbs and tissue cultures of Narcissus papyraceus and four varieties of N. tazetta. Journal of pharmaceutical and biomedical analysis. 2019 Aug; 172(?):230-237. doi: 10.1016/j.jpba.2019.04.043. [PMID: 31060036]
  • Shuangjiao Sun, Yanfen Wei, Yupin Cao, Biyang Deng. Simultaneous electrochemiluminescence determination of galanthamine, homolycorine, lycorenine, and tazettine in Lycoris radiata by capillary electrophoresis with ultrasonic-assisted extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Jun; 1055-1056(?):15-19. doi: 10.1016/j.jchromb.2017.04.020. [PMID: 28441543]
  • Marco Masi, Alet E van der Westhuyzen, Nurhayat Tabanca, Marco Evidente, Alessio Cimmino, Ivan R Green, Ulrich R Bernier, James J Becnel, Jeffrey R Bloomquist, Willem A L van Otterlo, Antonio Evidente. Sarniensine, a mesembrine-type alkaloid isolated from Nerine sarniensis, an indigenous South African Amaryllidaceae, with larvicidal and adulticidal activities against Aedes aegypti. Fitoterapia. 2017 Jan; 116(?):34-38. doi: 10.1016/j.fitote.2016.11.007. [PMID: 27864138]
  • Jean Paulo de Andrade, Natalia Belén Pigni, Laura Torras-Claveria, Strahil Berkov, Carles Codina, Francesc Viladomat, Jaume Bastida. Bioactive alkaloid extracts from Narcissus broussonetii: mass spectral studies. Journal of pharmaceutical and biomedical analysis. 2012 Nov; 70(?):13-25. doi: 10.1016/j.jpba.2012.05.009. [PMID: 22673940]
  • Susana López, Jaume Bastida, Francesc Viladomat, Carles Codina. Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus. Phytochemical analysis : PCA. 2002 Nov; 13(6):311-5. doi: 10.1002/pca.660. [PMID: 12494748]
  • Judit Hohmann, Peter Forgo, Joseph Molnár, Krisztina Wolfard, Annamária Molnár, Theresia Thalhammer, Imre Máthé, Derek Sharples. Antiproliferative amaryllidaceae alkaloids isolated from the bulbs of Sprekelia formosissima and Hymenocallis x festalis. Planta medica. 2002 May; 68(5):454-7. doi: 10.1055/s-2002-32068. [PMID: 12058326]
  • S W Baldwin, J S Debenham. Total syntheses of (-)-haemanthidine, (+)-pretazettine, and (+)-tazettine. Organic letters. 2000 Jan; 2(2):99-102. doi: 10.1021/ol9911472. [PMID: 10814256]