Phalloidine (BioDeep_00000002089)
代谢物信息卡片
Mast Cell Degranulating (MCD) Peptide
化学式: C35H48N8O11S (788.3163098)
中文名称: 伞形毒蕈中的鬼笔环肽
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C)C(C)O
InChI: InChI=1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28(48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,42,48)
描述信息
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:8040
- KEGG: C08439
- PubChem: 441542
- PubChem: 4752
- Metlin: METLIN66976
- MeSH: Phalloidine
- CAS: 17466-45-4
- PMhub: MS000001813
- PubChem: 10633
- KNApSAcK: C00001519
- NIKKAJI: J152.082B
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
12 个相关的物种来源信息
- 67723 Amanita phalloides:
- 235532 Amanita ocreata: 10.1021/NP50016A005
- 78357 Amanita virosa:
- 112270 Amanita verna: 10.1021/NP50016A005
- 87325 Amanita bisporigera: 10.1021/NP50016A005
- 500611 Amanita suballiacea: 10.1021/NP50031A012
- 67723 Amanita phalloides:
- 235532 Amanita ocreata: 10.1021/NP50016A005
- 78357 Amanita virosa:
- 112270 Amanita verna: 10.1021/NP50016A005
- 87325 Amanita bisporigera: 10.1021/NP50016A005
- 500611 Amanita suballiacea: 10.1021/NP50031A012
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Runan Hu, Yanjing Huang, Yuli Geng, Zhuo Liu, Fan Li, Zhuo Zhang, Wenwen Ma, Kunkun Song, Haoxu Dong, Yufan Song, Mingmin Zhang. Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication.
Journal of ethnopharmacology.
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Journal of molecular histology.
2023 Sep; ?(?):. doi:
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2023; 2604(?):13-24. doi:
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Journal of pharmacological sciences.
2022 Nov; 150(3):180-190. doi:
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Life sciences.
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Journal of biological engineering.
2011 Dec; 5(?):16. doi:
10.1186/1754-1611-5-16. [PMID: 22142483] - Paula Vainio, Laura Lehtinen, Tuomas Mirtti, Mika Hilvo, Tuulikki Seppänen-Laakso, Johannes Virtanen, Anna Sankila, Stig Nordling, Johan Lundin, Antti Rannikko, Matej Orešič, Olli Kallioniemi, Kristiina Iljin. Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.
Oncotarget.
2011 Dec; 2(12):1176-90. doi:
10.18632/oncotarget.397. [PMID: 22202492] - Jenny Wegert, Sabrina Bausenwein, Susanne Kneitz, Sabine Roth, Norbert Graf, Eva Geissinger, Manfred Gessler. Retinoic acid pathway activity in Wilms tumors and characterization of biological responses in vitro.
Molecular cancer.
2011 Nov; 10(?):136. doi:
10.1186/1476-4598-10-136. [PMID: 22067876] - Shilin Cheung, Laura J Fick, Denise D Belsham, David A Lovejoy, Michael Thompson. Interfacial behavior of immortalized hypothalamic mouse neurons detected by acoustic wave propagation.
The Analyst.
2011 Nov; 136(21):4412-21. doi:
10.1039/c1an15534b. [PMID: 21866285] - Helen J Hathaway, Kimberly S Butler, Natalie L Adolphi, Debbie M Lovato, Robert Belfon, Danielle Fegan, Todd C Monson, Jason E Trujillo, Trace E Tessier, Howard C Bryant, Dale L Huber, Richard S Larson, Edward R Flynn. Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors.
Breast cancer research : BCR.
2011 Nov; 13(5):R108. doi:
10.1186/bcr3050. [PMID: 22035507] - Stephen Vadia, Eusondia Arnett, Anne-Cécile Haghighat, Elisabeth M Wilson-Kubalek, Rodney K Tweten, Stephanie Seveau. The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytes.
PLoS pathogens.
2011 Nov; 7(11):e1002356. doi:
10.1371/journal.ppat.1002356. [PMID: 22072970] - Ying-Che Lu, Hong-Chen Chen. Involvement of lipid rafts in adhesion-induced activation of Met and EGFR.
Journal of biomedical science.
2011 Oct; 18(?):78. doi:
10.1186/1423-0127-18-78. [PMID: 22032640] - Deepak B Thimiri Govinda Raj, Bart Ghesquière, Arun Kumar Tharkeshwar, Katrijn Coen, Rita Derua, Dieter Vanderschaeghe, Evelien Rysman, Murali Bagadi, Pieter Baatsen, Bart De Strooper, Etienne Waelkens, Gustaaf Borghs, Nico Callewaert, Johan Swinnen, Kris Gevaert, Wim Annaert. A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes.
Molecular systems biology.
2011 Oct; 7(?):541. doi:
10.1038/msb.2011.74. [PMID: 22027552] - Ruxandra Bachmann-Gagescu, Ian G Phelps, George Stearns, Brian A Link, Susan E Brockerhoff, Cecilia B Moens, Dan Doherty. The ciliopathy gene cc2d2a controls zebrafish photoreceptor outer segment development through a role in Rab8-dependent vesicle trafficking.
Human molecular genetics.
2011 Oct; 20(20):4041-55. doi:
10.1093/hmg/ddr332. [PMID: 21816947] - Elena Lissina, Brian Young, Malene L Urbanus, Xue Li Guan, Jonathan Lowenson, Shawn Hoon, Anastasia Baryshnikova, Isabelle Riezman, Magali Michaut, Howard Riezman, Leah E Cowen, Markus R Wenk, Steven G Clarke, Guri Giaever, Corey Nislow. A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis.
PLoS genetics.
2011 Oct; 7(10):e1002332. doi:
10.1371/journal.pgen.1002332. [PMID: 22028670] - T Zampolla, E Spikings, D Rawson, T Zhang. Cytoskeleton proteins F-actin and tubulin distribution and interaction with mitochondria in the granulosa cells surrounding stage III zebrafish (Danio rerio) oocytes.
Theriogenology.
2011 Oct; 76(6):1110-9. doi:
10.1016/j.theriogenology.2011.05.018. [PMID: 21752457] - Eva Maria Díaz, Miguel Vicente-Manzanares, Mara Sacristan, Carlos Vicente, Maria-Estrella Legaz. Fungal lectin of Peltigera canina induces chemotropism of compatible Nostoc cells by constriction-relaxation pulses of cyanobiont cytoskeleton.
Plant signaling & behavior.
2011 Oct; 6(10):1525-36. doi:
10.4161/psb.6.10.16687. [PMID: 21897128] - Steven O'Reilly, Natalie Pollock, Laura Currie, Luminita Paraoan, Abbot F Clark, Ian Grierson. Inducers of cross-linked actin networks in trabecular meshwork cells.
Investigative ophthalmology & visual science.
2011 Sep; 52(10):7316-24. doi:
10.1167/iovs.10-6692. [PMID: 21849423] - Hongjie Zhang, Nessy Abraham, Liakot A Khan, David H Hall, John T Fleming, Verena Göbel. Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis.
Nature cell biology.
2011 Sep; 13(10):1189-201. doi:
10.1038/ncb2328. [PMID: 21926990] - Cherilyn A Elwell, Shaobo Jiang, Jung Hwa Kim, Albert Lee, Torsten Wittmann, Kentaro Hanada, Paul Melancon, Joanne N Engel. Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.
PLoS pathogens.
2011 Sep; 7(9):e1002198. doi:
10.1371/journal.ppat.1002198. [PMID: 21909260] - Gregory D Rak, Emily M Mace, Pinaki P Banerjee, Tatyana Svitkina, Jordan S Orange. Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse.
PLoS biology.
2011 Sep; 9(9):e1001151. doi:
10.1371/journal.pbio.1001151. [PMID: 21931536] - Juntao Liu, Yan Guo. The alkaline tolerance in Arabidopsis requires stabilizing microfilament partially through inactivation of PKS5 kinase.
Journal of genetics and genomics = Yi chuan xue bao.
2011 Jul; 38(7):307-13. doi:
10.1016/j.jgg.2011.05.006. [PMID: 21777855] - Qing-Ming Qin, Jijing Luo, Xiaorong Lin, Jianwu Pei, Lei Li, Thomas A Ficht, Paul de Figueiredo. Functional analysis of host factors that mediate the intracellular lifestyle of Cryptococcus neoformans.
PLoS pathogens.
2011 Jun; 7(6):e1002078. doi:
10.1371/journal.ppat.1002078. [PMID: 21698225] - Yun-Hoon Choung, Seung Won Kim, Chunjie Tian, Ji Young Min, Hae Kyoung Lee, Shi-Nae Park, Jong Bin Lee, Keehyun Park. Korean red ginseng prevents gentamicin-induced hearing loss in rats.
The Laryngoscope.
2011 Jun; 121(6):1294-302. doi:
10.1002/lary.21756. [PMID: 21541943] - Ebenezer O Farombi, Olatunde Owoeye. Antioxidative and chemopreventive properties of Vernonia amygdalina and Garcinia biflavonoid.
International journal of environmental research and public health.
2011 06; 8(6):2533-55. doi:
10.3390/ijerph8062533. [PMID: 21776245] - Yoshimasa Sagane, Julia Hosp, Karin Zech, Eric M Thompson. Cytoskeleton-mediated templating of complex cellulose-scaffolded extracellular structure and its association with oikosins in the urochordate Oikopleura.
Cellular and molecular life sciences : CMLS.
2011 May; 68(9):1611-22. doi:
10.1007/s00018-010-0547-8. [PMID: 20953655] - Hayato Yamamoto, Mihoko Sutoh, Shingo Hatakeyama, Yasuhiro Hashimoto, Takahiro Yoneyama, Takuya Koie, Hisao Saitoh, Kanemitsu Yamaya, Tomihisa Funyu, Toshiya Nakamura, Chikara Ohyama, Shigeru Tsuboi. Requirement for FBP17 in invadopodia formation by invasive bladder tumor cells.
The Journal of urology.
2011 May; 185(5):1930-8. doi:
10.1016/j.juro.2010.12.027. [PMID: 21421245] - Nilda E Rodríguez, Upasna Gaur Dixit, Lee-Ann H Allen, Mary E Wilson. Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages.
PloS one.
2011 Apr; 6(4):e19000. doi:
10.1371/journal.pone.0019000. [PMID: 21552562] - Young-Mi Go, Sang-Moo Kang, James R Roede, Michael Orr, Dean P Jones. Increased inflammatory signaling and lethality of influenza H1N1 by nuclear thioredoxin-1.
PloS one.
2011 Apr; 6(4):e18918. doi:
10.1371/journal.pone.0018918. [PMID: 21526215] - Hyun-Ja Jeong, Youngjin Choi, Min-Ho Kim, In-Cheol Kang, Jeong-Han Lee, Channy Park, Raekil Park, Hyung-Min Kim. Rosmarinic acid, active component of Dansam-Eum attenuates ototoxicity of cochlear hair cells through blockage of caspase-1 activity.
PloS one.
2011 Apr; 6(4):e18815. doi:
10.1371/journal.pone.0018815. [PMID: 21526214] - Ban Sato, Yohko U Katagiri, Kenji Miyado, Nozomu Okino, Makoto Ito, Hidenori Akutsu, Hajime Okita, Akihiro Umezawa, Junichiro Fujimoto, Kiyotaka Toshimori, Nobutaka Kiyokawa. Lipid rafts enriched in monosialylGb5Cer carrying the stage-specific embryonic antigen-4 epitope are involved in development of mouse preimplantation embryos at cleavage stage.
BMC developmental biology.
2011 Apr; 11(?):22. doi:
10.1186/1471-213x-11-22. [PMID: 21489308] - Brigitte E Blackman, Kathleen Horner, Julia Heidmann, Dan Wang, Wito Richter, Thomas C Rich, Marco Conti. PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts.
The Journal of biological chemistry.
2011 Apr; 286(14):12590-601. doi:
10.1074/jbc.m110.203604. [PMID: 21288894] - Anna L Khandoga, Dharmendra Pandey, Ulrich Welsch, Richard Brandl, Wolfgang Siess. GPR92/LPA₅ lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques.
Cardiovascular research.
2011 Apr; 90(1):157-64. doi:
10.1093/cvr/cvq369. [PMID: 21106562] - Robert J W Heath, John M Leong, Balázs Visegrády, Laura M Machesky, Ramnik J Xavier. Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3.
PLoS pathogens.
2011 Apr; 7(4):e1001332. doi:
10.1371/journal.ppat.1001332. [PMID: 21490959] - Nicola Bernabò, Paolo Berardinelli, Annunziata Mauro, Valentina Russo, Pia Lucidi, Mauro Mattioli, Barbara Barboni. The role of actin in capacitation-related signaling: an in silico and in vitro study.
BMC systems biology.
2011 Mar; 5(?):47. doi:
10.1186/1752-0509-5-47. [PMID: 21450097] - Anton Mihic, Vijay S Chauhan, Xiaodong Gao, Gavin Y Oudit, Robert G Tsushima. Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.
PloS one.
2011 Mar; 6(3):e18273. doi:
10.1371/journal.pone.0018273. [PMID: 21483829] - Mandi Wiley, Crystal Teygong, Eric Phelps, Jay Radke, Ira J Blader. Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells.
PloS one.
2011 Mar; 6(3):e18335. doi:
10.1371/journal.pone.0018335. [PMID: 21479245] - Miri Gitik, Sigal Liraz-Zaltsman, Per-Arne Oldenborg, Fanny Reichert, Shlomo Rotshenker. Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.
Journal of neuroinflammation.
2011 Mar; 8(?):24. doi:
10.1186/1742-2094-8-24. [PMID: 21401967] - Mary-Clare Cathcart, Kathy Gately, Robert Cummins, Elaine Kay, Kenneth J O'Byrne, Graham P Pidgeon. Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer.
Molecular cancer.
2011 Mar; 10(?):25. doi:
10.1186/1476-4598-10-25. [PMID: 21388528] - C Boykin, G Zhang, Y-H Chen, R-W Zhang, X-E Fan, W-M Yang, Q Lu. Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation.
British journal of cancer.
2011 Mar; 104(5):781-9. doi:
10.1038/bjc.2011.10. [PMID: 21304528] - Eamon Dubaissi, Nancy Papalopulu. Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease.
Disease models & mechanisms.
2011 Mar; 4(2):179-92. doi:
10.1242/dmm.006494. [PMID: 21183475] - Erik de Vries, Donna M Tscherne, Marleen J Wienholts, Viviana Cobos-Jiménez, Florine Scholte, Adolfo García-Sastre, Peter J M Rottier, Cornelis A M de Haan. Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway.
PLoS pathogens.
2011 Mar; 7(3):e1001329. doi:
10.1371/journal.ppat.1001329. [PMID: 21483486]