Fluridone (BioDeep_00000001987)

 

Secondary id: BioDeep_00001868057

human metabolite blood metabolite


代谢物信息卡片


1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-1,4-dihydropyridin-4-one

化学式: C19H14F3NO (329.10274300000003)
中文名称: 甲醇中氟啶草酮溶液
谱图信息: 最多检出来源 Homo sapiens(blood) 84.04%

分子结构信息

SMILES: CN1C=C(C(=O)C(=C1)C1=CC(=CC=C1)C(F)(F)F)C1=CC=CC=C1
InChI: InChI=1S/C19H14F3NO/c1-23-11-16(13-6-3-2-4-7-13)18(24)17(12-23)14-8-5-9-15(10-14)19(20,21)22/h2-12H,1H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 704; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8814; ORIGINAL_PRECURSOR_SCAN_NO 8813
CONFIDENCE standard compound; INTERNAL_ID 704; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8806; ORIGINAL_PRECURSOR_SCAN_NO 8805
CONFIDENCE standard compound; INTERNAL_ID 704; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8777; ORIGINAL_PRECURSOR_SCAN_NO 8775
CONFIDENCE standard compound; INTERNAL_ID 704; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8811; ORIGINAL_PRECURSOR_SCAN_NO 8810
CONFIDENCE standard compound; INTERNAL_ID 704; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8752; ORIGINAL_PRECURSOR_SCAN_NO 8747
CONFIDENCE standard compound; INTERNAL_ID 704; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8718; ORIGINAL_PRECURSOR_SCAN_NO 8717
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

2 个代谢物同义名

1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-1,4-dihydropyridin-4-one; FLURIDONE



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Sydney R Van Frost, Amber M White, Josie M Jauquet, Angela M Magness, Katherine D McMahon, Christina K Remucal. Laboratory measurements underestimate persistence of the aquatic herbicide fluridone in lakes. Environmental science. Processes & impacts. 2024 Jan; ?(?):. doi: 10.1039/d3em00537b. [PMID: 38189445]
  • Hahyun Park, Gwonhwa Song, Taeyeon Hong, Garam An, Sunwoo Park, Whasun Lim. Exposure to the herbicide fluridone induces cardiovascular toxicity in early developmental stages of zebrafish. The Science of the total environment. 2023 Apr; 867(?):161535. doi: 10.1016/j.scitotenv.2023.161535. [PMID: 36638995]
  • Jinpeng Sun, Jiawei Zan, Xiaonan Zang. Research of Fluridone's Effects on Growth and Pigment Accumulation of Haematococcus pluvialis Based on Transcriptome Sequencing. International journal of molecular sciences. 2022 Mar; 23(6):. doi: 10.3390/ijms23063122. [PMID: 35328543]
  • Angelo J Cozzola, Gavin K Dehnert, Amber M White, William H Karasov. Effects of subchronic exposure to environmentally relevant concentrations of a commercial fluridone formulation on fathead minnows (Pimephales promelas). Aquatic toxicology (Amsterdam, Netherlands). 2022 Mar; 244(?):106098. doi: 10.1016/j.aquatox.2022.106098. [PMID: 35121564]
  • Nasibeh Tavakoli Hasanaklou, Mohammad Sedghi, Foad Moradi, Ali Ebadi Khazineh Ghadim, Sodabeh Jahanbakhsh Ghodehkahriz. Greenhouse evaluation of branching, leaf yield and biochemical compositions of Stevia rebaudiana Bertoni to decapitation and foliar application of abscisic acid and fluridone. Functional plant biology : FPB. 2020 11; 47(12):1083-1097. doi: 10.1071/fp20045. [PMID: 32731921]
  • X Wang, J Zhang, J Song, M Huang, J Cai, Q Zhou, T Dai, D Jiang. Abscisic acid and hydrogen peroxide are involved in drought priming-induced drought tolerance in wheat (Triticum aestivum L.). Plant biology (Stuttgart, Germany). 2020 Nov; 22(6):1113-1122. doi: 10.1111/plb.13143. [PMID: 32530558]
  • Kumar Lama, Guy Harlev, Hadas Shafran, Reut Peer, Moshe A Flaishman. Anthocyanin accumulation is initiated by abscisic acid to enhance fruit color during fig (Ficus carica L.) ripening. Journal of plant physiology. 2020 Aug; 251(?):153192. doi: 10.1016/j.jplph.2020.153192. [PMID: 32554070]
  • Hai-Feng Liu, Xiao-Jing Xue, Yue Yu, Ming-Ming Xu, Chong-Chong Lu, Xuan-Lin Meng, Bao-Gang Zhang, Xin-Hua Ding, Zhao-Hui Chu. Copper ions suppress abscisic acid biosynthesis to enhance defence against Phytophthora infestans in potato. Molecular plant pathology. 2020 05; 21(5):636-651. doi: 10.1111/mpp.12919. [PMID: 32077242]
  • Leilane C Barreto, Daniela M D Herken, Brenda M R Silva, Sergi Munné-Bosch, Queila S Garcia. ABA and GA4 dynamic modulates secondary dormancy and germination in Syngonanthus verticillatus seeds. Planta. 2020 Mar; 251(4):86. doi: 10.1007/s00425-020-03378-2. [PMID: 32221719]
  • Sang Yeol Kim, Katherine M Warpeha, Steven C Huber. The brassinosteroid receptor kinase, BRI1, plays a role in seed germination and the release of dormancy by cold stratification. Journal of plant physiology. 2019 Oct; 241(?):153031. doi: 10.1016/j.jplph.2019.153031. [PMID: 31476676]
  • Cheng Zhou, Ninggao Ge, Jiansheng Guo, Lin Zhu, Zhongyou Ma, Shiyong Cheng, Jianfei Wang. Enterobacter asburiae Reduces Cadmium Toxicity in Maize Plants by Repressing Iron Uptake-Associated Pathways. Journal of agricultural and food chemistry. 2019 Sep; 67(36):10126-10136. doi: 10.1021/acs.jafc.9b03293. [PMID: 31433635]
  • P R M Souza-Filho, M Takaki. Germination constraints of dicarpic cypselae of Bidens pilosa L. Brazilian journal of biology = Revista brasleira de biologia. 2019 Jul; 79(3):383-394. doi: 10.1590/1519-6984.178222. [PMID: 30110080]
  • Ethan T Pierce, Benjamin P Graham, Michael R Stiff, Jason A Osborne, Candace H Haigler. Cultures of Gossypium barbadense cotton ovules offer insights into the microtubule-mediated control of fiber cell expansion. Planta. 2019 May; 249(5):1551-1563. doi: 10.1007/s00425-019-03106-5. [PMID: 30729290]
  • Kelly Laje, Mark Seger, Barry Dungan, Peter Cooke, Juergen Polle, F Omar Holguin. Phytoene Accumulation in the Novel Microalga Chlorococcum sp. Using the Pigment Synthesis Inhibitor Fluridone. Marine drugs. 2019 Mar; 17(3):. doi: 10.3390/md17030187. [PMID: 30909380]
  • Mingming Liu, Tatsunori Masatani, Paul Franck Adjou Moumouni, Seung-Hun Lee, Eloiza May Galon, Yang Gao, Huanping Guo, Jixu Li, Yongchang Li, Xuenan Xuan. Inhibitory effects of the phytohormone inhibitors fluridone and inabenfide against Babesia gibsoni in vitro. Veterinary parasitology. 2019 Jan; 265(?):19-23. doi: 10.1016/j.vetpar.2018.11.018. [PMID: 30638516]
  • Kumar Lama, Sharawan Yadav, Yogev Rosianski, Felix Shaya, Amnon Lichter, Lijuan Chai, Yardena Dahan, Zohar Freiman, Reut Peer, Moshe A Flaishman. The distinct ripening processes in the reproductive and non-reproductive parts of the fig syconium are driven by ABA. Journal of experimental botany. 2019 01; 70(1):115-131. doi: 10.1093/jxb/ery333. [PMID: 30239815]
  • Li Aihua, Jiang Shunyuan, Yang Guang, Li Ying, Guo Na, Chen Tong, Kang Liping, Huang Luqi. Molecular mechanism of seed dormancy release induced by fluridone compared with cod stratification in Notopterygium incisum. BMC plant biology. 2018 Jun; 18(1):116. doi: 10.1186/s12870-018-1333-2. [PMID: 29890940]
  • Kathlyn N Woolfson, Meghan L Haggitt, Yanni Zhang, Alexandra Kachura, Anica Bjelica, M Alejandra Rey Rincon, Karina M Kaberi, Mark A Bernards. Differential induction of polar and non-polar metabolism during wound-induced suberization in potato (Solanum tuberosum L.) tubers. The Plant journal : for cell and molecular biology. 2018 03; 93(5):931-942. doi: 10.1111/tpj.13820. [PMID: 29315972]
  • Kejun Yang, Yifei Zhang, Lianhua Zhu, Zuotong Li, Benliang Deng. Omethoate treatment mitigates high salt stress inhibited maize seed germination. Pesticide biochemistry and physiology. 2018 Jan; 144(?):79-82. doi: 10.1016/j.pestbp.2017.12.001. [PMID: 29463412]
  • Lidiya B Vysotskaya, Tatyana N Arkhipova, Guzel R Kudoyarova, Stanislav Yu Veselov. Dependence of growth inhibiting action of increased planting density on capacity of lettuce plants to synthesize ABA. Journal of plant physiology. 2018 Jan; 220(?):69-73. doi: 10.1016/j.jplph.2017.09.011. [PMID: 29149646]
  • B C Vieira, E M Bicalho, S Munné-Bosch, Q S Garcia. Abscisic acid regulates seed germination of Vellozia species in response to temperature. Plant biology (Stuttgart, Germany). 2017 Mar; 19(2):211-216. doi: 10.1111/plb.12515. [PMID: 27718313]
  • Wei Zheng, Tao Zhou, Jun Li, Deng-Kai Long, Wei-Ke Jiang, Ling Ding. [Cloning and expression analysis on full length CDS of zeaxanthin epoxidase gene in Pseudostellaria heterophylla]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2017 Feb; 42(4):669-674. doi: 10.19540/j.cnki.cjcmm.20170103.034. [PMID: 28959835]
  • Bulat Kuluev, Elena Mikhaylova, Zoya Berezhneva, Yuri Nikonorov, Bogdan Postrigan, Guzel Kudoyarova, Aleksey Chemeris. Expression profiles and hormonal regulation of tobacco NtEXGT gene and its involvement in abiotic stress response. Plant physiology and biochemistry : PPB. 2017 Feb; 111(?):203-215. doi: 10.1016/j.plaphy.2016.12.005. [PMID: 27940271]
  • Jie Zhang, Shaogui Guo, Yi Ren, Haiying Zhang, Guoyi Gong, Ming Zhou, Guizhang Wang, Mei Zong, Hongju He, Fan Liu, Yong Xu. High-level expression of a novel chromoplast phosphate transporter ClPHT4;2 is required for flesh color development in watermelon. The New phytologist. 2017 Feb; 213(3):1208-1221. doi: 10.1111/nph.14257. [PMID: 27787901]
  • Juanjuan Fu, Ye Wu, Yanjun Miao, Yamei Xu, Enhua Zhao, Jin Wang, Huaien Sun, Qian Liu, Yongwei Xue, Yuefei Xu, Tianming Hu. Improved cold tolerance in Elymus nutans by exogenous application of melatonin may involve ABA-dependent and ABA-independent pathways. Scientific reports. 2017 01; 7(?):39865. doi: 10.1038/srep39865. [PMID: 28045095]
  • Ya Zhou Bao, Zhao Qun Yao, Xiao Lei Cao, Jin Feng Peng, Ying Xu, Mei Xiu Chen, Si Feng Zhao. Transcriptome analysis of Phelipanche aegyptiaca seed germination mechanisms stimulated by fluridone, TIS108, and GR24. PloS one. 2017; 12(11):e0187539. doi: 10.1371/journal.pone.0187539. [PMID: 29099877]
  • Rochelle Haidee D Ybañez, Arpron Leesombun, Maki Nishimura, Ryuma Matsubara, Mikiko Kojima, Hitoshi Sakakibara, Kisaburo Nagamune, Yoshifumi Nishikawa. In vitro and in vivo effects of the phytohormone inhibitor fluridone against Neospora caninum infection. Parasitology international. 2016 Aug; 65(4):319-22. doi: 10.1016/j.parint.2016.03.009. [PMID: 27021922]
  • He Su, Yue Wang, Yang Yang, Xue-Hui Dong. [Effects of fluridone, gibberellin acid and germination temperature on dormancy-breaking for Epimedium wushanense]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2016 Jul; 41(14):2625-2632. doi: 10.4268/cjcmm20161410. [PMID: 28905597]
  • Xia Jin, Tao Sun, Xiatian Wang, Peipei Su, Jingfei Ma, Guangyuan He, Guangxiao Yang. Wheat CBL-interacting protein kinase 25 negatively regulates salt tolerance in transgenic wheat. Scientific reports. 2016 06; 6(?):28884. doi: 10.1038/srep28884. [PMID: 27358166]
  • Yongjie Meng, Feng Chen, Haiwei Shuai, Xiaofeng Luo, Jun Ding, Shengwen Tang, Shuanshuan Xu, Jianwei Liu, Weiguo Liu, Junbo Du, Jiang Liu, Feng Yang, Xin Sun, Taiwen Yong, Xiaochun Wang, Yuqi Feng, Kai Shu, Wenyu Yang. Karrikins delay soybean seed germination by mediating abscisic acid and gibberellin biogenesis under shaded conditions. Scientific reports. 2016 Feb; 6(?):22073. doi: 10.1038/srep22073. [PMID: 26902640]
  • Yan-Xu Yin, Shu-Bin Wang, Huai-Xia Zhang, Huai-Juan Xiao, Jing-Hao Jin, Jiao-Jiao Ji, Hua Jing, Ru-Gang Chen, Mohamed Hamed Arisha, Zhen-Hui Gong. Cloning and expression analysis of CaPIP1-1 gene in pepper (Capsicum annuum L.). Gene. 2015 May; 563(1):87-93. doi: 10.1016/j.gene.2015.03.012. [PMID: 25770051]
  • Hong Gil Lee, Kyounghee Lee, Pil Joon Seo. The Arabidopsis MYB96 transcription factor plays a role in seed dormancy. Plant molecular biology. 2015 Mar; 87(4-5):371-81. doi: 10.1007/s11103-015-0283-4. [PMID: 25616734]
  • L A Stetsenko, N P Vedenicheva, R V Likhnevsky, V V Kuznetsov. [Influence of abscisic acid and fluridone on the content of phytohormones and polyamines and the level of oxidative stress in plants of Mesembryanthemum crystallinum L. under salinity]. Izvestiia Akademii nauk. Seriia biologicheskaia. 2015 Mar; ?(2):134-44. doi: . [PMID: 26021155]
  • Danica E Goggin, R J Neil Emery, Leonid V Kurepin, Stephen B Powles. A potential role for endogenous microflora in dormancy release, cytokinin metabolism and the response to fluridone in Lolium rigidum seeds. Annals of botany. 2015 Feb; 115(2):293-301. doi: 10.1093/aob/mcu231. [PMID: 25471097]
  • Kazuhide Rikiishi, Takakazu Matsuura, Yoko Ikeda, Masahiko Maekawa. Light Inhibition of Shoot Regeneration Is Regulated by Endogenous Abscisic Acid Level in Calli Derived from Immature Barley Embryos. PloS one. 2015; 10(12):e0145242. doi: 10.1371/journal.pone.0145242. [PMID: 26670930]
  • Danica E Goggin, Stephen B Powles. Fluridone: a combination germination stimulant and herbicide for problem fields?. Pest management science. 2014 Sep; 70(9):1418-24. doi: 10.1002/ps.3721. [PMID: 24408127]
  • Helena M P Garcês, Daniel Koenig, Brad T Townsley, Minsung Kim, Neelima R Sinha. Truncation of LEAFY COTYLEDON1 protein is required for asexual reproduction in Kalanchoë daigremontiana. Plant physiology. 2014 May; 165(1):196-206. doi: 10.1104/pp.114.237222. [PMID: 24664206]
  • Mirko Magnone, Sonia Scarfì, Laura Sturla, Lucrezia Guida, Salvatore Cuzzocrea, Rosanna Di Paola, Santina Bruzzone, Annalisa Salis, Antonio De Flora, Elena Zocchi. Fluridone as a new anti-inflammatory drug. European journal of pharmacology. 2013 Nov; 720(1-3):7-15. doi: 10.1016/j.ejphar.2013.10.058. [PMID: 24211328]
  • Hao Du, Nai Wu, Yu Chang, Xianghua Li, Jinghua Xiao, Lizhong Xiong. Carotenoid deficiency impairs ABA and IAA biosynthesis and differentially affects drought and cold tolerance in rice. Plant molecular biology. 2013 Nov; 83(4-5):475-88. doi: 10.1007/s11103-013-0103-7. [PMID: 23846670]
  • Wenxiu Ye, Mohammad Anowar Hossain, Shintaro Munemasa, Yoshimasa Nakamura, Izumi C Mori, Yoshiyuki Murata. Endogenous abscisic acid is involved in methyl jasmonate-induced reactive oxygen species and nitric oxide production but not in cytosolic alkalization in Arabidopsis guard cells. Journal of plant physiology. 2013 Sep; 170(13):1212-5. doi: 10.1016/j.jplph.2013.03.011. [PMID: 23608742]
  • Kamrun Nahar, Tina Kyndt, Yasinta Beda Nzogela, Godelieve Gheysen. Abscisic acid interacts antagonistically with classical defense pathways in rice-migratory nematode interaction. The New phytologist. 2012 Nov; 196(3):901-913. doi: 10.1111/j.1469-8137.2012.04310.x. [PMID: 22985247]
  • Jana Piterková, Lenka Luhová, Jakub Hofman, Veronika Turecková, Ondrej Novák, Marek Petrivalsky, Martin Fellner. Nitric oxide is involved in light-specific responses of tomato during germination under normal and osmotic stress conditions. Annals of botany. 2012 Sep; 110(4):767-76. doi: 10.1093/aob/mcs141. [PMID: 22782244]
  • Amanda Rasmussen, Christine A Beveridge, Danny Geelen. Inhibition of strigolactones promotes adventitious root formation. Plant signaling & behavior. 2012 Jun; 7(6):694-7. doi: 10.4161/psb.20224. [PMID: 22580687]
  • Mei-rong Zhao, Yang-yang Han, Ya-nan Feng, Feng Li, Wei Wang. Expansins are involved in cell growth mediated by abscisic acid and indole-3-acetic acid under drought stress in wheat. Plant cell reports. 2012 Apr; 31(4):671-85. doi: 10.1007/s00299-011-1185-9. [PMID: 22076248]
  • Beimi Cui, Zongsuo Liang, Yan Liu, Fenghua Liu, Jianguo Zhu. [Effects of ABA and its biosynthetic inhibitor fluridone on accumulation of penolic acids and activity of PAL and TAT in hairy root of Salvia miltiorrhiza]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Mar; 37(6):754-9. doi: 10.4268/cjcmm20120614. [PMID: 22715716]
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  • Lixin Zhang, Mei Gao, Jingjiang Hu, Xifeng Zhang, Kai Wang, Muhammad Ashraf. Modulation Role of abscisic acid (ABA) on growth, water relations and glycinebetaine metabolism in two maize (Zea mays L.) cultivars under drought stress. International journal of molecular sciences. 2012; 13(3):3189-3202. doi: 10.3390/ijms13033189. [PMID: 22489148]
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