Ibotenic acid (BioDeep_00001873996)
Main id: BioDeep_00000008194
PANOMIX_OTCML-2023 Volatile Flavor Compounds
代谢物信息卡片
化学式: C5H6N2O4 (158.0327556)
中文名称: 鹅膏氨酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(ONC1=O)C(C(=O)O)N
InChI: InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
描述信息
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018690 - Excitatory Amino Acid Agonists
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
同义名列表
4 个代谢物同义名
Ibotenic acid; (RS)-Ibotenic acid; DL-Ibotenic acid; Ibotenic acid
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:5854
- KEGG: C10600
- PubChem: 1233
- ChEMBL: CHEMBL284895
- MeSH: Ibotenic Acid
- KNApSAcK: C00002345
- CAS: 2552-55-8
- PubChem: 12783
- 3DMET: B05450
- NIKKAJI: J7.613I
- medchemexpress: HY-N2311
- KNApSAcK: 5854
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Alexander Dushkov, Zuzana Vosáhlová, Alexander Tzintzarov, Květa Kalíková, Tomáš Křížek, Iva Ugrinova. Analysis of the Ibotenic Acid, Muscimol, and Ergosterol Content of an Amanita Muscaria Hydroalcoholic Extract with an Evaluation of Its Cytotoxic Effect against a Panel of Lung Cell Lines In Vitro.
Molecules (Basel, Switzerland).
2023 Sep; 28(19):. doi:
10.3390/molecules28196824
. [PMID: 37836667] - Yu-Ting Su, Jie Liu, Dan-Ni Yang, Qing Cai, Zhu L Yang, Zuo-Hong Chen. Determination of ibotenic acid and muscimol in species of the genus Amanita section Amanita from China.
Toxicon : official journal of the International Society on Toxinology.
2023 Aug; ?(?):107257. doi:
10.1016/j.toxicon.2023.107257
. [PMID: 37611670] - Young-A Lee, Yu-Jeong Kim, Ju Sung Lee, Sanghyun Lee, Yukiori Goto. Imbalance between dopamine and serotonin caused by neonatal habenula lesion.
Behavioural brain research.
2021 07; 409(?):113316. doi:
10.1016/j.bbr.2021.113316
. [PMID: 33901435] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Ljubica Vucicevic, Maja Misirkic, Darko Ciric, Tamara Martinovic, Maja Jovanovic, Aleksandra Isakovic, Ivanka Markovic, Jasna Saponjic, Marc Foretz, Yoana Rabanal-Ruiz, Viktor I Korolchuk, Vladimir Trajkovic. Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells.
Cellular and molecular life sciences : CMLS.
2020 Sep; 77(17):3383-3399. doi:
10.1007/s00018-019-03356-2
. [PMID: 31720741] - Xiao-Min Xu, Jing-Shun Zhang, Bai-Fen Huang, Jian-Long Han, Qing Chen. Determination of ibotenic acid and muscimol in plasma by liquid chromatography-triple quadrupole mass spectrometry with bimolecular dansylation.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Jun; 1146(?):122128. doi:
10.1016/j.jchromb.2020.122128
. [PMID: 32361630] - Anna Posod, Karina Wechselberger, Anna Schmid, Eva Huber, Martina Urbanek, Ursula Kiechl-Kohlendorfer, Elke Griesmaier. Excitotoxicity Alters Endogenous Secretoneurin Plasma Levels, but Supplementation with Secretoneurin Does Not Protect Against Excitotoxic Neonatal Brain Injury.
Neuroscience.
2019 07; 410(?):239-253. doi:
10.1016/j.neuroscience.2019.05.023
. [PMID: 31121260] - Megan C Romano, Hung K Doan, Robert H Poppenga, Michael S Filigenzi, Uneeda K Bryant, Cynthia L Gaskill. Fatal Amanita muscaria poisoning in a dog confirmed by PCR identification of mushrooms.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2019 May; 31(3):485-487. doi:
10.1177/1040638719842897
. [PMID: 30957709] - Michael J Moss, Robert G Hendrickson. Toxicity of muscimol and ibotenic acid containing mushrooms reported to a regional poison control center from 2002-2016.
Clinical toxicology (Philadelphia, Pa.).
2019 02; 57(2):99-103. doi:
10.1080/15563650.2018.1497169
. [PMID: 30073844] - Uyen Vy Doan, Bomar Mendez Rojas, Ralph Kirby. Unintentional ingestion of Cordyceps fungus-infected cicada nymphs causing ibotenic acid poisoning in Southern Vietnam.
Clinical toxicology (Philadelphia, Pa.).
2017 Sep; 55(8):893-896. doi:
10.1080/15563650.2017.1319066
. [PMID: 28463017] - Benjamin J Blaise, Leslie Schwendimann, Vibol Chhor, Vincent Degos, Mark P Hodson, Guido Dallmann, Matthias Keller, Pierre Gressens, Bobbi Fleiss. Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury.
Developmental neuroscience.
2017; 39(1-4):182-191. doi:
10.1159/000464131
. [PMID: 28494460] - Nan Zong, Fei Li, Yuanyuan Deng, Jingshan Shi, Feng Jin, Qihai Gong. Icariin, a major constituent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus.
Behavioural brain research.
2016 10; 313(?):111-119. doi:
10.1016/j.bbr.2016.06.055
. [PMID: 27368415] - Julien Pansiot, Hoa Pham, Jeremie Dalous, Didier Chevenne, Marina Colella, Leslie Schwendimann, Assia Fafouri, Jérôme Mairesse, Raffaella Moretti, Anne-Laure Schang, Christiane Charriaut-Marlangue, Pierre Gressens, Olivier Baud. Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury.
Experimental neurology.
2016 08; 282(?):56-65. doi:
10.1016/j.expneurol.2016.05.024
. [PMID: 27222132] - Xue-Qin Hou, Lei Zhang, Cong Yang, Cui-Ping Rong, Wen-Qing He, Chun-Xia Zhang, Shi Li, Ru-Yu Su, Xiang Chang, Ji-Huan Qin, Yun-Bo Chen, Shao-Xiang Xian, Qi Wang. Alleviating effects of Bushen-Yizhi formula on ibotenic acid-induced cholinergic impairments in rat.
Rejuvenation research.
2015 Apr; 18(2):111-27. doi:
10.1089/rej.2014.1603
. [PMID: 25482164] - S Deja, E Jawień, I Jasicka-Misiak, M Halama, P Wieczorek, P Kafarski, P Młynarz. Rapid determination of ibotenic acid and muscimol in human urine.
Magnetic resonance in chemistry : MRC.
2014 Nov; 52(11):711-4. doi:
10.1002/mrc.4104
. [PMID: 25042675] - Pavlína Ginterová, Barbora Sokolová, Peter Ondra, Joanna Znaleziona, Jan Petr, Juraj Ševčík, Vítězslav Maier. Determination of mushroom toxins ibotenic acid, muscimol and muscarine by capillary electrophoresis coupled with electrospray tandem mass spectrometry.
Talanta.
2014 Jul; 125(?):242-7. doi:
10.1016/j.talanta.2014.03.019
. [PMID: 24840440] - Hiroshi Ikeda, Syuntaro Takasu, Kazuyuki Murase. Contribution of anterior cingulate cortex and descending pain inhibitory system to analgesic effect of lemon odor in mice.
Molecular pain.
2014 Feb; 10(?):14. doi:
10.1186/1744-8069-10-14
. [PMID: 24555533] - Chi Zhang, Jie Chen, Chengcheng Feng, Xiayan Shao, Qingfeng Liu, Qizhi Zhang, Zhiqing Pang, Xinguo Jiang. Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease.
International journal of pharmaceutics.
2014 Jan; 461(1-2):192-202. doi:
10.1016/j.ijpharm.2013.11.049
. [PMID: 24300213] - Dana Ekstein, Felix Benninger, Moshe Daninos, Julika Pitsch, Karen M J van Loo, Albert J Becker, Yoel Yaari. Zinc induces long-term upregulation of T-type calcium current in hippocampal neurons in vivo.
The Journal of physiology.
2012 Nov; 590(22):5895-905. doi:
10.1113/jphysiol.2012.242537
. [PMID: 22930274] - Jan Stříbrný, Miloš Sokol, Barbora Merová, Peter Ondra. GC/MS determination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina.
International journal of legal medicine.
2012 Jul; 126(4):519-24. doi:
10.1007/s00414-011-0599-9
. [PMID: 21751026] - Young-A Lee, Yukiori Goto. Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons.
PloS one.
2011 Apr; 6(4):e19450. doi:
10.1371/journal.pone.0019450
. [PMID: 21559387] - Yuko Hiroshima, Hajime Nakae, Kunio Gommori. Amanita ibotengutake intoxication treated with plasma exchange.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2010 Oct; 14(5):483-4. doi:
10.1111/j.1744-9987.2010.00862.x
. [PMID: 21175547] - Ulrika Adén, Géraldine Favrais, Frank Plaisant, Max Winerdal, Ursula Felderhoff-Mueser, Jon Lampa, Vincent Lelièvre, Pierre Gressens. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
Brain, behavior, and immunity.
2010 Jul; 24(5):747-58. doi:
10.1016/j.bbi.2009.10.010
. [PMID: 19861157] - Z Zhao, S Zhao, N Xu, C Yu, S Guan, X Liu, L Huang, W Liao, W Jia. Lovastatin improves neurological outcome after nucleus basalis magnocellularis lesion in rats.
Neuroscience.
2010 May; 167(3):954-63. doi:
10.1016/j.neuroscience.2010.02.054
. [PMID: 20219644] - Frédéric Chauveau, Christophe Piérard, Marc Corio, Aurélie Célérier, Tronche Christophe, Rose Marie Vouimba, J L Guillou, Daniel Béracochéa. Mediodorsal thalamic lesions block the stress-induced inversion of serial memory retrieval pattern in mice.
Behavioural brain research.
2009 Nov; 203(2):270-8. doi:
10.1016/j.bbr.2009.05.014
. [PMID: 19464320] - Cher V Masini, Sarah K Sasse, Robert J Garcia, Tara J Nyhuis, Heidi E W Day, Serge Campeau. Disruption of neuroendocrine stress responses to acute ferret odor by medial, but not central amygdala lesions in rats.
Brain research.
2009 Sep; 1288(?):79-87. doi:
10.1016/j.brainres.2009.07.011
. [PMID: 19615352] - Jennifer François, Arielle Ferrandon, Estelle Koning, Marie-José Angst, Guy Sandner, Astrid Nehlig. Selective reorganization of GABAergic transmission in neonatal ventral hippocampal-lesioned rats.
The international journal of neuropsychopharmacology.
2009 Sep; 12(8):1097-110. doi:
10.1017/s1461145709009985
. [PMID: 19267957] - Farshad Homayouni Moghadam, Hojatoallah Alaie, Khadije Karbalaie, Somayeh Tanhaei, Mohammad Hossein Nasr Esfahani, Hossein Baharvand. Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in Alzheimerian rats.
Differentiation; research in biological diversity.
2009 Sep; 78(2-3):59-68. doi:
10.1016/j.diff.2009.06.005
. [PMID: 19616885] - Jerome H Pagani, Jeffrey B Rosen. The medial hypothalamic defensive circuit and 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) induced fear: comparison of electrolytic and neurotoxic lesions.
Brain research.
2009 Aug; 1286(?):133-46. doi:
10.1016/j.brainres.2009.06.062
. [PMID: 19559688] - Jason J Radley, Kristin L Gosselink, Paul E Sawchenko. A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2009 Jun; 29(22):7330-40. doi:
10.1523/jneurosci.5924-08.2009
. [PMID: 19494154] - Hwon Heo, Yongsung Shin, Woohee Cho, YoonSeok Choi, Hocheol Kim, Yunhee Kim Kwon. Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis.
Journal of ethnopharmacology.
2009 Feb; 122(1):20-7. doi:
10.1016/j.jep.2008.11.026
. [PMID: 19111602] - Chao Ji, Qing Li, HajiAkber Aisa, Nan Yang, Yi-Long Dong, Yan-Yong Liu, Tao Wang, Qiang Hao, Hai-Bo Zhu, Ping-Ping Zuo. Gossypium herbaceam extracts attenuate ibotenic acid-induced excitotoxicity in rat hippocampus.
Journal of Alzheimer's disease : JAD.
2009; 16(2):331-9. doi:
10.3233/jad-2009-0979
. [PMID: 19221423] - Martin Williamson, Victor Viau. Selective contributions of the medial preoptic nucleus to testosterone-dependant regulation of the paraventricular nucleus of the hypothalamus and the HPA axis.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Oct; 295(4):R1020-30. doi:
10.1152/ajpregu.90389.2008
. [PMID: 18685071] - Barbora Merova, Peter Ondra, Marie Stankova, Ivo Valka. Isolation and identification of the Amanita muscaria and Amanita pantherina toxins in human urine.
Neuro endocrinology letters.
2008 Oct; 29(5):744-8. doi:
NULL
. [PMID: 18987593] - F Chauveau, C Piérard, M Coutan, I Drouet, P Liscia, D Béracochéa. Prefrontal cortex or basolateral amygdala lesions blocked the stress-induced inversion of serial memory retrieval pattern in mice.
Neurobiology of learning and memory.
2008 Sep; 90(2):395-403. doi:
10.1016/j.nlm.2008.04.014
. [PMID: 18572424] - Dennis C Choi, Amy R Furay, Nathan K Evanson, Yvonne M Ulrich-Lai, Mary M N Nguyen, Michelle M Ostrander, James P Herman. The role of the posterior medial bed nucleus of the stria terminalis in modulating hypothalamic-pituitary-adrenocortical axis responsiveness to acute and chronic stress.
Psychoneuroendocrinology.
2008 Jun; 33(5):659-69. doi:
10.1016/j.psyneuen.2008.02.006
. [PMID: 18378095] - Mirela B Dias, Tatiane B Nucci, Lisandra O Margatho, José Antunes-Rodrigues, Luciane H Gargaglioni, Luiz G S Branco. Raphe magnus nucleus is involved in ventilatory but not hypothermic response to CO2.
Journal of applied physiology (Bethesda, Md. : 1985).
2007 Nov; 103(5):1780-8. doi:
10.1152/japplphysiol.00424.2007
. [PMID: 17823301] - Gergely Sárközy, Elke Griesmaier, Xiangying He, Klaus Kapelari, Martina Urbanek, Georg Simbruner, Pierre Gressens, Matthias Keller. T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.
2007 May; 11(3):129-35. doi:
10.1016/j.ejpn.2006.11.009
. [PMID: 17222575] - Michelle C Naylor, Mesfin Negia, Meredith Noetzel, Terry C Burns, Zach L Demorest, Walter C Low. Heparan sulfate mediates neuroprotection from degeneration in experimental glutaric aciduria.
Cell transplantation.
2007; 16(3):187-95. doi:
10.3727/000000007783464786
. [PMID: 17503732] - Moonkyu Kang, Ji-Hyun Kim, Chongwoon Cho, Kwang-Yeun Lee, Minkyu Shin, Moochang Hong, Insop Shim, Hyunsu Bae. Effects of Yukmijihwang-tang derivatives (YMJd) on ibotenic acid-induced amnesia in the rat.
Biological & pharmaceutical bulletin.
2006 Jul; 29(7):1431-5. doi:
10.1248/bpb.29.1431
. [PMID: 16819183] - I A Kostanian, S S Zhokhov, Z I Storozheva, A T Proshin, E A Surina, I I Babichenko, V V Sherstnev, V M Lipkin. [Neuroprotective effect of the hexapeptide HLDF-6 on neurons of rat hippocampus on the model of Alzheimer's disease in vivo and in vitro].
Bioorganicheskaia khimiia.
2006 Jul; 32(4):399-407. doi:
NULL
. [PMID: 16909864] - Anne-Pierre S Goursaud, Sally P Mendoza, John P Capitanio. Do neonatal bilateral ibotenic acid lesions of the hippocampal formation or of the amygdala impair HPA axis responsiveness and regulation in infant rhesus macaques (Macaca mulatta)?.
Brain research.
2006 Feb; 1071(1):97-104. doi:
10.1016/j.brainres.2005.11.027
. [PMID: 16412391] - Shadi Adeli-Rankouhi, Hiroyuki Umegaki, Waner Zhu, Yusuke Suzuki, Shinobu Kurotani-Ohara, Satsuki Ieda, Akihisa Iguchi. The entorhinal cortex regulates blood glucose level in response to microinjection of neostigmine into the hippocampus.
Neuro endocrinology letters.
2005 Jun; 26(3):225-30. doi:
. [PMID: 15990726]
- Christine Adde-Michel, Olivier Hennebert, Vincent Laudenbach, Stéphane Marret, Philippe Leroux. Effect of perinatal alcohol exposure on ibotenic acid-induced excitotoxic cortical lesions in newborn hamsters.
Pediatric research.
2005 Feb; 57(2):287-93. doi:
10.1203/01.pdr.0000148712.30716.9d
. [PMID: 15585688] - Ya Li, Hai-Qiang Qin, Qi-Sheng Chen, Jian-Jun Wang. Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein1-40 and ibotenic acid in rats.
Life sciences.
2005 Jan; 76(11):1189-97. doi:
10.1016/j.lfs.2004.05.039
. [PMID: 15642590] - Ji Hyun Kim, Jin Yong Chung, Young Jae Lee, Sepill Park, Jang Hyun Kim, Dae Hyun Hahm, Hye Jung Lee, Insop Shim. Effects of methanol extract of Uncariae Ramulus et Uncus on ibotenic acid-induced amnesia in the rat.
Journal of pharmacological sciences.
2004 Nov; 96(3):314-23. doi:
10.1254/jphs.fp0040179
. [PMID: 15557736] - John H Halpern. Hallucinogens and dissociative agents naturally growing in the United States.
Pharmacology & therapeutics.
2004 May; 102(2):131-8. doi:
10.1016/j.pharmthera.2004.03.003
. [PMID: 15163594] - Sanjeev K Bhardwaj, Remi Quirion, Lalit K Srivastava. Post-pubertal adrenergic changes in rats with neonatal lesions of the ventral hippocampus.
Neuropharmacology.
2004 Jan; 46(1):85-94. doi:
10.1016/j.neuropharm.2003.08.001
. [PMID: 14654100] - Gwenaëlle Le Pen, James Kew, Daniela Alberati, Edilio Borroni, Marie Paule Heitz, Jean-Luc Moreau. Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.
Biological psychiatry.
2003 Dec; 54(11):1162-70. doi:
10.1016/s0006-3223(03)00374-3
. [PMID: 14643083] - Alejandra Rangel, Luis E Gonzalez, Vanessa Villarroel, Luis Hernandez. Anxiolysis followed by anxiogenesis relates to coping and corticosterone after medial prefrontal cortical damage in rats.
Brain research.
2003 Nov; 992(1):96-103. doi:
10.1016/j.brainres.2003.08.038
. [PMID: 14604777] - Thomas C Chou, Thomas E Scammell, Joshua J Gooley, Stephanie E Gaus, Clifford B Saper, Jun Lu. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2003 Nov; 23(33):10691-702. doi:
10.1523/jneurosci.23-33-10691.2003
. [PMID: 14627654] - Helmer F Figueiredo, Amy Bruestle, Bryan Bodie, Charles M Dolgas, James P Herman. The medial prefrontal cortex differentially regulates stress-induced c-fos expression in the forebrain depending on type of stressor.
The European journal of neuroscience.
2003 Oct; 18(8):2357-64. doi:
10.1046/j.1460-9568.2003.02932.x
. [PMID: 14622198] - M J Sullivan, J T Cunningham, D Mazzella, A M Allen, R Nissen, L P Renaud. Lesions of the diagonal band of broca enhance drinking in the rat.
Journal of neuroendocrinology.
2003 Oct; 15(10):907-15. doi:
10.1046/j.1365-2826.2003.01066.x
. [PMID: 12969234] - Osamu Inoue, Rie Hosoi, Sotaro Momosaki, Kaoru Kobayashi, Takayo Kida, Kazutoshi Suzuki, Antony Gee. Ionic interaction of [11C]-N,alpha-dimethylbenzylamine (DMBA) in rodent brain.
Annals of nuclear medicine.
2003 Sep; 17(6):469-73. doi:
10.1007/bf03006437
. [PMID: 14575382] - Frode A Tuvnes, Hill-Aina Steffenach, Robert Murison, May-Britt Moser, Edvard I Moser. Selective hippocampal lesions do not increase adrenocortical activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2003 May; 23(10):4345-54. doi:
10.1523/jneurosci.23-10-04345.2003
. [PMID: 12764123] - M S Todtenkopf, J R Stellar, R H Melloni. Neither ibotenic acid nor volkensin lesions of the nucleus accumbens shell affect the expression of cocaine sensitization.
The European journal of neuroscience.
2002 Aug; 16(3):541-6. doi:
10.1046/j.1460-9568.2002.02121.x
. [PMID: 12193198] - W Zhu, H Umegaki, Y Suzuki, H Miura, A Iguchi. Involvement of the bed nucleus of the stria terminalis in hippocampal cholinergic system-mediated activation of the hypothalamo--pituitary--adrenocortical axis in rats.
Brain research.
2001 Oct; 916(1-2):101-6. doi:
10.1016/s0006-8993(01)02871-2
. [PMID: 11597596] - J Patkai, B Mesples, M A Dommergues, G Fromont, E M Thornton, J C Renauld, P Evrard, P Gressens. Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain.
Pediatric research.
2001 Aug; 50(2):222-30. doi:
10.1203/00006450-200108000-00010
. [PMID: 11477207] - F White, J A Nicoll, K Horsburgh. Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion.
Experimental neurology.
2001 Jun; 169(2):307-18. doi:
10.1006/exnr.2001.7655
. [PMID: 11358444] - M L Blair, R L Jaworski, A Want, D T Piekut. Parabrachial nucleus modulates cardiovascular responses to blood loss.
American journal of physiology. Regulatory, integrative and comparative physiology.
2001 Apr; 280(4):R1141-8. doi:
10.1152/ajpregu.2001.280.4.r1141
. [PMID: 11247837] - T Wichmann, M A Kliem, M R DeLong. Antiparkinsonian and behavioral effects of inactivation of the substantia nigra pars reticulata in hemiparkinsonian primates.
Experimental neurology.
2001 Feb; 167(2):410-24. doi:
10.1006/exnr.2000.7572
. [PMID: 11161630] - J C Caldeira, C R Franci. Prolactin and corticosterone secretion in response to acute stress after paraventricular nucleus lesion by ibotenic acid.
Brain research bulletin.
2000 Aug; 52(6):483-9. doi:
10.1016/s0361-9230(00)00284-7
. [PMID: 10974487] - J Hu, Q Wang, W Liang. [Effects of bushen yizhi recipe on somatostatin-like immunopositive and somatostatin messenger ribonucleic acid expressed-positive neurons in Alzheimer's disease model rats].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2000 Jul; 20(7):533-5. doi:
. [PMID: 11789215]
- K W Nettles, C Pesold, M B Goldman. Influence of the ventral hippocampal formation on plasma vasopressin, hypothalamic-pituitary-adrenal axis, and behavioral responses to novel acoustic stress.
Brain research.
2000 Mar; 858(1):181-90. doi:
10.1016/s0006-8993(99)02281-7
. [PMID: 10700613] - M O Urban, P K Zahn, G F Gebhart. Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat.
Neuroscience.
1999 May; 90(2):349-52. doi:
10.1016/s0306-4522(99)00002-0
. [PMID: 10215139] - C Tsai. The caudal subnucleus caudalis (medullary dorsal horn) acts as an interneuronal relay site in craniofacial nociceptive reflex activity.
Brain research.
1999 May; 826(2):293-7. doi:
10.1016/s0006-8993(99)01248-2
. [PMID: 10224307] - C M Tsai, C Y Chiang, X M Yu, B J Sessle. Involvement of trigeminal subnucleus caudalis (medullary dorsal horn) in craniofacial nociceptive reflex activity.
Pain.
1999 May; 81(1-2):115-28. doi:
10.1016/s0304-3959(99)00009-3
. [PMID: 10353499] - M L Blair, A Want, J A Olschowka, D Piekut. Role of paraventricular nucleus parvicellular neurons in the compensatory responses to graded hemorrhage.
The American journal of physiology.
1998 07; 275(1):R278-85. doi:
10.1152/ajpregu.1998.275.1.r278
. [PMID: 9688989] - M Ogawa, H Fukuyama, Y Ouchi, H Yamauchi, S Matsuzaki, J Kimura, H Tsukada. Uncoupling between cortical glucose metabolism and blood flow after ibotenate lesion of the rat basal forebrain: a PET study.
Neuroscience letters.
1996 Feb; 204(3):193-6. doi:
10.1016/0304-3940(96)12355-7
. [PMID: 8938263] - Y Ouchi, H Fukuyama, M Ogawa, H Yamauchi, J Kimura, Y Magata, Y Yonekura, J Konishi. Cholinergic projection from the basal forebrain and cerebral glucose metabolism in rats: a dynamic PET study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
1996 Jan; 16(1):34-41. doi:
10.1097/00004647-199601000-00004
. [PMID: 8530553] - G S Alema, P Casolini, F R Patacchioli, L Angelucci. Rat brain corticosteriod receptors are modulated by septo-hippocampal cholinergic innervation.
Neuroreport.
1995 Dec; 6(18):2461-4. doi:
10.1097/00001756-199512150-00006
. [PMID: 8741742] - I P Chessell, P T Francis, D M Bowen. Changes in cortical nicotinic acetylcholine receptor numbers following unilateral destruction of pyramidal neurones by intrastriatal volkensin injection.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.
1995 Dec; 4(4):415-24. doi:
10.1006/neur.1995.0050
. [PMID: 8846235] - C Joly, J Gomeza, I Brabet, K Curry, J Bockaert, J P Pin. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1995 May; 15(5 Pt 2):3970-81. doi:
10.1523/jneurosci.15-05-03970.1995
. [PMID: 7751958] - M L Earle, Q J Pittman. Involvement of the PVN and BST in 1K1C hypertension in the rat.
Brain research.
1995 Jan; 669(1):41-7. doi:
10.1016/0006-8993(94)01222-4
. [PMID: 7712163] - L D Van de Kar, P A Rittenhouse, Q Li, A D Levy, M S Brownfield. Hypothalamic paraventricular, but not supraoptic neurons, mediate the serotonergic stimulation of oxytocin secretion.
Brain research bulletin.
1995; 36(1):45-50. doi:
10.1016/0361-9230(94)00161-s
. [PMID: 7882048] - A J Sedman, H Bockbrader, R D Schwarz. Preclinical and phase 1 clinical characterization of CI-979/RU35926, a novel muscarinic agonist for the treatment of Alzheimer's disease.
Life sciences.
1995; 56(11-12):877-82. doi:
10.1016/0024-3205(95)00023-y
. [PMID: 10188788] - C Thomsen, A Bau, P Faarup, C Foged, A Kanstrup, P D Suzdak. Effects of bromohomoibotenate on metabotropic glutamate receptors.
Neuroreport.
1994 Dec; 5(18):2417-20. doi:
10.1097/00001756-199412000-00003
. [PMID: 7696571] - L H Mortensen, L E Ohman, J R Haywood. Effects of lateral parabrachial nucleus lesions in chronic renal hypertensive rats.
Hypertension (Dallas, Tex. : 1979).
1994 Jun; 23(6 Pt 1):774-80. doi:
10.1161/01.hyp.23.6.774
. [PMID: 8206576] - P V Holmes, R C Drugan. Amygdaloid central nucleus lesions and cholinergic blockade attenuate the response of the renal peripheral benzodiazepine receptor to stress.
Brain research.
1993 Sep; 621(1):1-9. doi:
10.1016/0006-8993(93)90291-t
. [PMID: 8221058] - C Thomsen, E R Mulvihill, B Haldeman, D S Pickering, D R Hampson, P D Suzdak. A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Brain research.
1993 Aug; 619(1-2):22-8. doi:
10.1016/0006-8993(93)91592-g
. [PMID: 7690672] - P A Rittenhouse, A D Levy, Q Li, C L Bethea, L D Van de Kar. Neurons in the hypothalamic paraventricular nucleus mediate the serotonergic stimulation of prolactin secretion via 5-HT1c/2 receptors.
Endocrinology.
1993 Aug; 133(2):661-7. doi:
10.1210/endo.133.2.8344205
. [PMID: 8344205] - C J Kerry, H L Sudan, K Abutidze, I R Mellor, E A Barnard, P N Usherwood. Reconstitution of glutamate receptor proteins purified from Xenopus central nervous system into artificial bilayers.
Molecular pharmacology.
1993 Jul; 44(1):142-52. doi:
"
. [PMID: 7688068] - J A Lawrence, H J Olverman, K Shirakawa, J S Kelly, S P Butcher. Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions.
Brain research.
1993 May; 612(1-2):326-9. doi:
10.1016/0006-8993(93)91680-q
. [PMID: 7687192] - S L Erdö, N Cai, V Lakics. Medium-dependent dissociation of cytotoxic and GABA-releasing effects of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and kainate in rat cortical cultures.
Neuroscience letters.
1993 Apr; 152(1-2):84-6. doi:
10.1016/0304-3940(93)90489-8
. [PMID: 7685870] - M E Cid, A Ortega. Glutamate stimulates [3H]phorbol 12,13-dibutyrate binding in cultured Bergmann glia cells.
European journal of pharmacology.
1993 Mar; 245(1):51-4. doi:
10.1016/0922-4106(93)90168-9
. [PMID: 7682963] - T S Gray, R A Piechowski, J M Yracheta, P A Rittenhouse, C L Bethea, L D Van de Kar. Ibotenic acid lesions in the bed nucleus of the stria terminalis attenuate conditioned stress-induced increases in prolactin, ACTH and corticosterone.
Neuroendocrinology.
1993 Mar; 57(3):517-24. doi:
10.1159/000126400
. [PMID: 8391664] - V Vodyanoy, B A Bahr, V Suppiramaniam, R A Hall, M Baudry, G Lynch. Single channel recordings of reconstituted AMPA receptors reveal low and high conductance states.
Neuroscience letters.
1993 Feb; 150(1):80-4. doi:
10.1016/0304-3940(93)90113-y
. [PMID: 7682309] - M V Catania, Z Hollingsworth, J B Penney, A B Young. Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence.
Journal of neurochemistry.
1993 Jan; 60(1):236-45. doi:
10.1111/j.1471-4159.1993.tb05843.x
. [PMID: 7678040] - R A Hall, M Kessler, G Lynch. Evidence that high- and low-affinity DL-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding sites reflect membrane-dependent states of a single receptor.
Journal of neurochemistry.
1992 Dec; 59(6):1997-2004. doi:
10.1111/j.1471-4159.1992.tb10086.x
. [PMID: 1279120] - M F Callahan, C R Thore, D K Sundberg, K A Gruber, K O'Steen, M Morris. Excitotoxin paraventricular nucleus lesions: stress and endocrine reactivity and oxytocin mRNA levels.
Brain research.
1992 Nov; 597(1):8-15. doi:
10.1016/0006-8993(92)91499-5
. [PMID: 1477737] - B A Bahr, V Vodyanoy, R A Hall, V Suppiramaniam, M Kessler, K Sumikawa, G Lynch. Functional reconstitution of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors from rat brain.
Journal of neurochemistry.
1992 Nov; 59(5):1979-82. doi:
10.1111/j.1471-4159.1992.tb11038.x
. [PMID: 1383430] - P A Rittenhouse, Q Li, A D Levy, L D Van de Kar. Neurons in the hypothalamic paraventricular nucleus mediate the serotonergic stimulation of renin secretion.
Brain research.
1992 Oct; 593(1):105-13. doi:
10.1016/0006-8993(92)91270-o
. [PMID: 1458311] - J M Henley, A Ambrosini, D Rodriguez-Ithurralde, H Sudan, P Brackley, C Kerry, I Mellor, K Abutidze, P N Usherwood, E A Barnard. Purified unitary kainate/alpha-amino-3-hydroxy-5-methylisooxazole-propionate (AMPA) and kainate/AMPA/N-methyl-D-aspartate receptors with interchangeable subunits.
Proceedings of the National Academy of Sciences of the United States of America.
1992 Jun; 89(11):4806-10. doi:
10.1073/pnas.89.11.4806
. [PMID: 1375752] - C D Blackstone, S J Moss, L J Martin, A I Levey, D L Price, R L Huganir. Biochemical characterization and localization of a non-N-methyl-D-aspartate glutamate receptor in rat brain.
Journal of neurochemistry.
1992 Mar; 58(3):1118-26. doi:
10.1111/j.1471-4159.1992.tb09370.x
. [PMID: 1371146] - A L Smith, R A McIlhinney. Effects of acromelic acid A on the binding of [3H]-kainic acid and [3H]-AMPA to rat brain synaptic plasma membranes.
British journal of pharmacology.
1992 Jan; 105(1):83-6. doi:
10.1111/j.1476-5381.1992.tb14214.x
. [PMID: 1375859] - G R Stewart, J W Olney, M Pathikonda, W D Snider. Excitotoxicity in the embryonic chick spinal cord.
Annals of neurology.
1991 Dec; 30(6):758-66. doi:
10.1002/ana.410300604
. [PMID: 1686386] - A A Farooqui, L J Wallace, L A Horrocks. Stimulation of mono- and diacylglycerol lipase activities in ibotenate-induced lesions of nucleus basalis magnocellularis.
Neuroscience letters.
1991 Sep; 131(1):97-9. doi:
10.1016/0304-3940(91)90345-t
. [PMID: 1791985] - L D Van de Kar, R A Piechowski, P A Rittenhouse, T S Gray. Amygdaloid lesions: differential effect on conditioned stress and immobilization-induced increases in corticosterone and renin secretion.
Neuroendocrinology.
1991 Aug; 54(2):89-95. doi:
10.1159/000125856
. [PMID: 1766554] - D W Brewster, J Warren, W E Hopkins. Metabolism of glyphosate in Sprague-Dawley rats: tissue distribution, identification, and quantitation of glyphosate-derived materials following a single oral dose.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1991 Jul; 17(1):43-51. doi:
10.1016/0272-0590(91)90237-x
. [PMID: 1916078]