Ibotenic acid (BioDeep_00001873996)

Main id: BioDeep_00000008194

 

PANOMIX_OTCML-2023


代谢物信息卡片


Ibotenic acid

化学式: C5H6N2O4 (158.0327556)
中文名称: 鹅膏氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(ONC1=O)C(C(=O)O)N
InChI: InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)

描述信息

D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018690 - Excitatory Amino Acid Agonists
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.

同义名列表

3 个代谢物同义名

Ibotenic acid; (RS)-Ibotenic acid; DL-Ibotenic acid



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Alexander Dushkov, Zuzana Vosáhlová, Alexander Tzintzarov, Květa Kalíková, Tomáš Křížek, Iva Ugrinova. Analysis of the Ibotenic Acid, Muscimol, and Ergosterol Content of an Amanita Muscaria Hydroalcoholic Extract with an Evaluation of Its Cytotoxic Effect against a Panel of Lung Cell Lines In Vitro. Molecules (Basel, Switzerland). 2023 Sep; 28(19):. doi: 10.3390/molecules28196824. [PMID: 37836667]
  • Yu-Ting Su, Jie Liu, Dan-Ni Yang, Qing Cai, Zhu L Yang, Zuo-Hong Chen. Determination of ibotenic acid and muscimol in species of the genus Amanita section Amanita from China. Toxicon : official journal of the International Society on Toxinology. 2023 Aug; ?(?):107257. doi: 10.1016/j.toxicon.2023.107257. [PMID: 37611670]
  • Young-A Lee, Yu-Jeong Kim, Ju Sung Lee, Sanghyun Lee, Yukiori Goto. Imbalance between dopamine and serotonin caused by neonatal habenula lesion. Behavioural brain research. 2021 07; 409(?):113316. doi: 10.1016/j.bbr.2021.113316. [PMID: 33901435]
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  • Ljubica Vucicevic, Maja Misirkic, Darko Ciric, Tamara Martinovic, Maja Jovanovic, Aleksandra Isakovic, Ivanka Markovic, Jasna Saponjic, Marc Foretz, Yoana Rabanal-Ruiz, Viktor I Korolchuk, Vladimir Trajkovic. Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells. Cellular and molecular life sciences : CMLS. 2020 Sep; 77(17):3383-3399. doi: 10.1007/s00018-019-03356-2. [PMID: 31720741]
  • Xiao-Min Xu, Jing-Shun Zhang, Bai-Fen Huang, Jian-Long Han, Qing Chen. Determination of ibotenic acid and muscimol in plasma by liquid chromatography-triple quadrupole mass spectrometry with bimolecular dansylation. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2020 Jun; 1146(?):122128. doi: 10.1016/j.jchromb.2020.122128. [PMID: 32361630]
  • Anna Posod, Karina Wechselberger, Anna Schmid, Eva Huber, Martina Urbanek, Ursula Kiechl-Kohlendorfer, Elke Griesmaier. Excitotoxicity Alters Endogenous Secretoneurin Plasma Levels, but Supplementation with Secretoneurin Does Not Protect Against Excitotoxic Neonatal Brain Injury. Neuroscience. 2019 07; 410(?):239-253. doi: 10.1016/j.neuroscience.2019.05.023. [PMID: 31121260]
  • Megan C Romano, Hung K Doan, Robert H Poppenga, Michael S Filigenzi, Uneeda K Bryant, Cynthia L Gaskill. Fatal Amanita muscaria poisoning in a dog confirmed by PCR identification of mushrooms. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2019 May; 31(3):485-487. doi: 10.1177/1040638719842897. [PMID: 30957709]
  • Michael J Moss, Robert G Hendrickson. Toxicity of muscimol and ibotenic acid containing mushrooms reported to a regional poison control center from 2002-2016. Clinical toxicology (Philadelphia, Pa.). 2019 02; 57(2):99-103. doi: 10.1080/15563650.2018.1497169. [PMID: 30073844]
  • Uyen Vy Doan, Bomar Mendez Rojas, Ralph Kirby. Unintentional ingestion of Cordyceps fungus-infected cicada nymphs causing ibotenic acid poisoning in Southern Vietnam. Clinical toxicology (Philadelphia, Pa.). 2017 Sep; 55(8):893-896. doi: 10.1080/15563650.2017.1319066. [PMID: 28463017]
  • Benjamin J Blaise, Leslie Schwendimann, Vibol Chhor, Vincent Degos, Mark P Hodson, Guido Dallmann, Matthias Keller, Pierre Gressens, Bobbi Fleiss. Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury. Developmental neuroscience. 2017; 39(1-4):182-191. doi: 10.1159/000464131. [PMID: 28494460]
  • Nan Zong, Fei Li, Yuanyuan Deng, Jingshan Shi, Feng Jin, Qihai Gong. Icariin, a major constituent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus. Behavioural brain research. 2016 10; 313(?):111-119. doi: 10.1016/j.bbr.2016.06.055. [PMID: 27368415]
  • Julien Pansiot, Hoa Pham, Jeremie Dalous, Didier Chevenne, Marina Colella, Leslie Schwendimann, Assia Fafouri, Jérôme Mairesse, Raffaella Moretti, Anne-Laure Schang, Christiane Charriaut-Marlangue, Pierre Gressens, Olivier Baud. Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury. Experimental neurology. 2016 08; 282(?):56-65. doi: 10.1016/j.expneurol.2016.05.024. [PMID: 27222132]
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  • Hwon Heo, Yongsung Shin, Woohee Cho, YoonSeok Choi, Hocheol Kim, Yunhee Kim Kwon. Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis. Journal of ethnopharmacology. 2009 Feb; 122(1):20-7. doi: 10.1016/j.jep.2008.11.026. [PMID: 19111602]
  • Chao Ji, Qing Li, HajiAkber Aisa, Nan Yang, Yi-Long Dong, Yan-Yong Liu, Tao Wang, Qiang Hao, Hai-Bo Zhu, Ping-Ping Zuo. Gossypium herbaceam extracts attenuate ibotenic acid-induced excitotoxicity in rat hippocampus. Journal of Alzheimer's disease : JAD. 2009; 16(2):331-9. doi: 10.3233/jad-2009-0979. [PMID: 19221423]
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