Diphenylamine (BioDeep_00001871662)

Main id: BioDeep_00000001669

 

Volatile Flavor Compounds natural product


代谢物信息卡片


Diphenylamine

化学式: C12H11N (169.0891446)
中文名称: 甲醇中二苯胺溶液, 二苯胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)NC2=CC=CC=C2
InChI: InChI=1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H

描述信息

同义名列表

3 个代谢物同义名

Diphenylamine; Diphenylamine; Diphenylamine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yi-Dan Ma, Huan Zhou, Guo-Tai Lin, Ke-Huan Wu, Gong Xu, Xili Liu, Dan Xu. Design, Synthesis, and Fungicidal Activities of Novel N-(Pyrazol-5-yl)benzamide Derivatives Containing a Diphenylamine Moiety. Journal of agricultural and food chemistry. 2024 Mar; 72(12):6691-6701. doi: 10.1021/acs.jafc.3c07567. [PMID: 38498985]
  • Peter Lees, Pierre-Louis Toutain, Jonathan Elliott, Jerome M Giraudel, Ludovic Pelligand, Jonathan N King. Pharmacology, safety, efficacy and clinical uses of the COX-2 inhibitor robenacoxib. Journal of veterinary pharmacology and therapeutics. 2022 Jul; 45(4):325-351. doi: 10.1111/jvp.13052. [PMID: 35460083]
  • Verónica Vieitez, Victor López-Rámis, Rafael Barrera, Ignacio A Gómez de Segura. Serum C-reactive protein and iron levels following gonadectomy are not modified by perioperative administration of robenacoxib to dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2022 Jan; 86(1):40-47. doi: . [PMID: 34975221]
  • Jonathan N King, Wolfgang Seewald, Sophie Forster, Gabriele Friton, Derek E Adrian, B Duncan X Lascelles. Clinical safety of robenacoxib in cats with chronic musculoskeletal disease. Journal of veterinary internal medicine. 2021 Sep; 35(5):2384-2394. doi: 10.1111/jvim.16148. [PMID: 34196973]
  • L Hinder, A L Pfaff, R E Emmerich, S Michels, M Schlitzer, C Culmsee. Characterization of Novel Diphenylamine Compounds as Ferroptosis Inhibitors. The Journal of pharmacology and experimental therapeutics. 2021 08; 378(2):184-196. doi: 10.1124/jpet.121.000534. [PMID: 34011530]
  • Juliette Raulic, Francis Beaudry, Guy Beauchamp, Marion Jalenques, Noémie Summa, Stéphane Lair, Wahiba Ait Youcef, Claire Vergneau-Grosset. PHARMACOKINETIC, PHARMACODYNAMIC, AND TOXICOLOGY STUDY OF ROBENACOXIB IN RAINBOW TROUT (ONCORHYNCHUS MYKISS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2021 Jun; 52(2):529-537. doi: 10.1638/2020-0130. [PMID: 34130395]
  • Jonathan N King, Martin Jung. Determination of the route of excretion of robenacoxib (Onsior™) in cats and dogs: A pilot study. Journal of veterinary pharmacology and therapeutics. 2021 May; 44(3):411-416. doi: 10.1111/jvp.12973. [PMID: 33881783]
  • Yu Katata, Shin-Ichi Inoue, Atsuko Asao, Shuhei Kobayashi, Hitoshi Terui, Aya Inoue-Shibui, Taiki Abe, Tetsuya Niihori, Setsuya Aiba, Naoto Ishii, Shigeo Kure, Yoko Aoki. Costello syndrome model mice with a HrasG12S/+ mutation are susceptible to develop house dust mite-induced atopic dermatitis. Cell death & disease. 2020 08; 11(8):617. doi: 10.1038/s41419-020-02845-8. [PMID: 32792500]
  • Aigui Zhang, Ying Yue, Jian Yang, Jiaxing Shi, Ke Tao, Hong Jin, Taiping Hou. Design, Synthesis, and Antifungal Activities of Novel Aromatic Carboxamides Containing a Diphenylamine Scaffold. Journal of agricultural and food chemistry. 2019 May; 67(17):5008-5016. doi: 10.1021/acs.jafc.9b00151. [PMID: 30977370]
  • Zhe Lu, Amila O De Silva, Wenjia Zhou, Gerald R Tetreault, Shane R de Solla, Patricia A Fair, Magali Houde, Greg Bossart, Derek C G Muir. Substituted diphenylamine antioxidants and benzotriazole UV stabilizers in blood plasma of fish, turtles, birds and dolphins from North America. The Science of the total environment. 2019 Jan; 647(?):182-190. doi: 10.1016/j.scitotenv.2018.07.405. [PMID: 30081360]
  • Sukanya Ramaraj, Mani Sakthivel, Shen-Ming Chen, Kuo-Chuan Ho. Ultrasound-assisted synthesis of two-dimensional layered ytterbium substituted molybdenum diselenide nanosheets with excellent electrocatalytic activity for the electrochemical detection of diphenylamine anti-scald agent in fruit extract. Ultrasonics sonochemistry. 2019 Jan; 50(?):265-277. doi: 10.1016/j.ultsonch.2018.09.028. [PMID: 30287180]
  • Yasmin Schuermann, Monique T Rovani, Bernardo Gasperin, Rogério Ferreira, Juliana Ferst, Ejimedo Madogwe, Paulo B Gonçalves, Vilceu Bordignon, Raj Duggavathi. ERK1/2-dependent gene expression in the bovine ovulating follicle. Scientific reports. 2018 11; 8(1):16170. doi: 10.1038/s41598-018-34015-4. [PMID: 30385793]
  • Norihiko Oyama, Tadashi Sano, Mizuki Yamamori, Jun Tamura, Mohammed Ahmed Umar, Yusuke Endo, Yusyun Ishikawa, Akifumi Itoh, Kenjirou Miyoshi, Kazuto Yamashita. Influence of sevoflurane anesthesia with mechanical ventilation and fluid-therapy on distribution of subcutaneously administered robenacoxib in dogs. The Journal of veterinary medical science. 2018 Sep; 80(9):1450-1455. doi: 10.1292/jvms.17-0356. [PMID: 30078791]
  • Céline E Toutain, Patrick Brossard, Stephen B King, Rainer Helbig. Six-month safety evaluation of robenacoxib tablets (Onsior™) in dogs after daily oral administrations. BMC veterinary research. 2018 Aug; 14(1):242. doi: 10.1186/s12917-018-1566-1. [PMID: 30119677]
  • Evangelos Karagiannis, Michail Michailidis, Georgia Tanou, Martina Samiotaki, Katerina Karamanoli, Evangelia Avramidou, Ioannis Ganopoulos, Panagiotis Madesis, Athanassios Molassiotis. Ethylene -dependent and -independent superficial scald resistance mechanisms in 'Granny Smith' apple fruit. Scientific reports. 2018 07; 8(1):11436. doi: 10.1038/s41598-018-29706-x. [PMID: 30061655]
  • Gong Yihui, Jun Song, Lina Du, Mindy Vinqvist, Leslie Campbell Palmer, Sherry Fillmore, XueQun Pang, ZhaoQi Zhang. Characterization of laccase from apple fruit during postharvest storage and its response to diphenylamine and 1-methylcyclopropene treatments. Food chemistry. 2018 Jul; 253(?):314-321. doi: 10.1016/j.foodchem.2018.01.142. [PMID: 29502838]
  • Cuiping Li, Weiyi Lai, Hailin Wang. An Alternative Culture Method to Maintain Genomic Hypomethylation of Mouse Embryonic Stem Cells Using MEK Inhibitor PD0325901 and Vitamin C. Journal of visualized experiments : JoVE. 2018 06; ?(136):. doi: 10.3791/56391. [PMID: 29912180]
  • Matthew A Summers, Emily R Vasiljevski, Kathy Mikulec, Lauren Peacock, David G Little, Aaron Schindeler. Developmental dosing with a MEK inhibitor (PD0325901) rescues myopathic features of the muscle-specific but not limb-specific Nf1 knockout mouse. Molecular genetics and metabolism. 2018 04; 123(4):518-525. doi: 10.1016/j.ymgme.2018.02.009. [PMID: 29477258]
  • Zev A Wainberg, Maria Alsina, Heloisa P Soares, Irene Braña, Carolyn D Britten, Gianluca Del Conte, Patrick Ezeh, Brett Houk, Kenneth A Kern, Stephen Leong, Nuzhat Pathan, Kristen J Pierce, Lillian L Siu, Jennifer Vermette, Josep Tabernero. A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer. Targeted oncology. 2017 Dec; 12(6):775-785. doi: 10.1007/s11523-017-0530-5. [PMID: 29067643]
  • Jian-Zhong Xu, Wei-Guo Zhang. Menaquinone-7 production from maize meal hydrolysate by Bacillus isolates with diphenylamine and analogue resistance. Journal of Zhejiang University. Science. B. 2017 Jun; 18(6):462-473. doi: 10.1631/jzus.b1600127. [PMID: 28585422]
  • Jean-Luc Van Laethem, Hanno Riess, Jacek Jassem, Michael Haas, Uwe M Martens, Colin Weekes, Marc Peeters, Paul Ross, John Bridgewater, Bohuslav Melichar, Stefano Cascinu, Piotr Saramak, Patrick Michl, David Van Brummelen, Alberto Zaniboni, Wollf Schmiegel, Svein Dueland, Marius Giurescu, Vittorio L Garosi, Katrin Roth, Anke Schulz, Henrik Seidel, Prabhu Rajagopalan, Michael Teufel, Barrett H Childs. Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer. Targeted oncology. 2017 02; 12(1):97-109. doi: 10.1007/s11523-016-0469-y. [PMID: 27975152]
  • A Panteri, A Kukk, C Desevaux, W Seewald, J N King. Effect of benazepril and robenacoxib and their combination on glomerular filtration rate in dogs. Journal of veterinary pharmacology and therapeutics. 2017 Jan; 40(1):44-56. doi: 10.1111/jvp.12325. [PMID: 27302598]
  • Roxana Sühring, Xavier Ortiz, Miren Pena-Abaurrea, Karl J Jobst, Marko Freese, Jan-Dag Pohlmann, Lasse Marohn, Ralf Ebinghaus, Sean Backus, Reinhold Hanel, Eric J Reiner. Evidence for High Concentrations and Maternal Transfer of Substituted Diphenylamines in European Eels Analyzed by Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry and Gas Chromatography-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Environmental science & technology. 2016 12; 50(23):12678-12685. doi: 10.1021/acs.est.6b04382. [PMID: 27791360]
  • C Marcela Diaz-Montero, Frances J Mao, John Barnard, Yvonne Parker, Maryam Zamanian-Daryoush, John J Pink, James H Finke, Brian I Rini, Daniel J Lindner. MEK inhibition abrogates sunitinib resistance in a renal cell carcinoma patient-derived xenograft model. British journal of cancer. 2016 10; 115(8):920-928. doi: 10.1038/bjc.2016.263. [PMID: 27560553]
  • Selvakumar Subramaniam, Mehmet Hakan Ozdener, Souleymane Abdoul-Azize, Katsuyoshi Saito, Bilal Malik, Guillaume Maquart, Toshihiro Hashimoto, Philippe Marambaud, Mourad Aribi, Michael G Tordoff, Philippe Besnard, Naim Akhtar Khan. ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2016 10; 30(10):3489-3500. doi: 10.1096/fj.201600422r. [PMID: 27358389]
  • Zhe Lu, Thomas E Peart, Cyril J Cook, Amila O De Silva. Simultaneous determination of substituted diphenylamine antioxidants and benzotriazole ultra violet stabilizers in blood plasma and fish homogenates by ultra high performance liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. A. 2016 Aug; 1461(?):51-8. doi: 10.1016/j.chroma.2016.07.027. [PMID: 27425756]
  • Jonathan N King, Stephen King, Steven C Budsberg, B Duncan X Lascelles, Stephen E Bienhoff, Linda M Roycroft, Elizabeth S Roberts. Clinical safety of robenacoxib in feline osteoarthritis: results of a randomized, blinded, placebo-controlled clinical trial. Journal of feline medicine and surgery. 2016 08; 18(8):632-42. doi: 10.1177/1098612x15590870. [PMID: 26058587]
  • Domingos Pf Almeida, Rita Carvalho, Eve Dupille. Efficacy of 1-methylcyclopropene on the mitigation of storage disorders of "Rocha" pear under normal refrigerated and controlled atmospheres. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2016 Jul; 22(5):399-409. doi: 10.1177/1082013215610026. [PMID: 26437671]
  • Jonathan N King, Alessandro Panteri, Melanie Graille, Wolfgang Seewald, Gabriele Friton, Cyril Desevaux. Effect of benazepril, robenacoxib and their combination on glomerular filtration rate in cats. BMC veterinary research. 2016 Jun; 12(1):124. doi: 10.1186/s12917-016-0734-4. [PMID: 27338786]
  • Alex A Adjei, Donald A Richards, Anthony El-Khoueiry, Fadi Braiteh, Carlos H R Becerra, Joe J Stephenson, Aram F Hezel, Morris Sherman, Lawrence Garbo, Diane P Leffingwell, Cory Iverson, Jeffrey N Miner, Zancong Shen, Li-Tain Yeh, Sonny Gunawan, David M Wilson, Kimberly J Manhard, Prabhu Rajagopalan, Heiko Krissel, Neil J Clendeninn. A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 05; 22(10):2368-76. doi: 10.1158/1078-0432.ccr-15-1681. [PMID: 26644411]
  • Di Li, Linli Wang, Jundi Hou, Qun Shen, Qianyu Chen, Xiaoshan Wang, Juan Du, Xiujuan Cai, Yongli Shan, Tian Zhang, Tiancheng Zhou, Xi Shi, Yuhua Li, Hua Zhang, Guangjin Pan. Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder. Stem cell reports. 2016 05; 6(5):717-728. doi: 10.1016/j.stemcr.2016.04.001. [PMID: 27132887]
  • Huichao Li, Aiying Guan, Guang Huang, Chang-Ling Liu, Zhinian Li, Yong Xie, Jie Lan. Design, synthesis and structure-activity relationship of novel diphenylamine derivatives. Bioorganic & medicinal chemistry. 2016 Feb; 24(3):453-61. doi: 10.1016/j.bmc.2015.09.032. [PMID: 26432603]
  • Xueying Luo, Binlong Zhong, Xian Hong, Yurong Cui, Ying Gao, Mengmeng Yin, Ming Tang, Jürgen Hescheler, Jiaoya Xi. Puerarin Exerts a Delayed Inhibitory Effect on the Proliferation of Cardiomyocytes Derived from Murine ES Cells via Slowing Progression through G2/M Phase. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2016; 38(4):1333-42. doi: 10.1159/000443077. [PMID: 27008508]
  • L Pelligand, N Suemanotham, J N King, W Seewald, H Syme, K Smith, P Lees, J Elliott. Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC veterinary research. 2015 Dec; 11(?):296. doi: 10.1186/s12917-015-0598-z. [PMID: 26634699]
  • Justyna Sekuła, Joanna Nizioł, Maria Misiorek, Paulina Dec, Agnieszka Wrona, Adrian Arendowski, Tomasz Ruman. Gold nanoparticle-enhanced target for MS analysis and imaging of harmful compounds in plant, animal tissue and on fingerprint. Analytica chimica acta. 2015 Oct; 895(?):45-53. doi: 10.1016/j.aca.2015.09.003. [PMID: 26454458]
  • Vaibhav Sidarala, Rajakrishnan Veluthakal, Khadija Syeda, Anjaneyulu Kowluru. EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells. Cellular signalling. 2015 Jun; 27(6):1159-67. doi: 10.1016/j.cellsig.2015.02.020. [PMID: 25725286]
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