Lawsone (BioDeep_00000180408)

   

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


4-hydroxy-1,2-dihydronaphthalene-1,2-dione

化学式: C10H6O3 (174.0317)
中文名称: 2-羟基-1,4-萘醌
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 50%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CC(=O)C2=O)O
InChI: InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H

描述信息

D020011 - Protective Agents > D011837 - Radiation-Protective Agents > D013473 - Sunscreening Agents
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
D003879 - Dermatologic Agents
D004791 - Enzyme Inhibitors
D004396 - Coloring Agents
D003358 - Cosmetics
Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity[1].
Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity[1].

同义名列表

10 个代谢物同义名

4-hydroxy-1,2-dihydronaphthalene-1,2-dione; 2-Hydroxy-1,4-naphthoquinone; 2-hydroxynaphthoquinone; lawsone, sodium salt; sodium lawsonate; henna dye; lawsonin; NQ-2-OH; Lawsone; Lawsone



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AHR, ALB, AXIN2, BCL2, CASP3, CAT, CDK1, CRYZ, EGFR, G6PD, NQO1, RNF25, XDH
Peripheral membrane protein 2 ACHE, G6PD
Endosome membrane 2 ECE1, EGFR
Endoplasmic reticulum membrane 3 BCL2, CDK1, EGFR
Nucleus 10 ACHE, AHR, ALB, AXIN2, BCL2, CASP3, CDK1, EGFR, NQO1, RNF25
cytosol 12 AHR, ALB, AXIN2, BCL2, CASP3, CAT, CDK1, CRYZ, G6PD, NQO1, RNF25, XDH
dendrite 1 NQO1
centrosome 3 ALB, AXIN2, CDK1
nucleoplasm 3 AHR, CASP3, CDK1
Cell membrane 4 ACHE, ECE1, EGFR, TNF
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 1 MT-CYB
Synapse 2 ACHE, NQO1
cell junction 1 EGFR
cell surface 3 ACHE, EGFR, TNF
glutamatergic synapse 2 CASP3, EGFR
Golgi apparatus 2 ACHE, ALB
Golgi membrane 1 EGFR
lysosomal membrane 3 ECE1, EGF, GAA
mitochondrial inner membrane 1 MT-CYB
neuromuscular junction 1 ACHE
neuronal cell body 3 CASP3, NQO1, TNF
Cytoplasm, cytosol 2 G6PD, NQO1
Lysosome 1 GAA
endosome 2 ECE1, EGFR
plasma membrane 8 ACHE, AXIN2, BCHE, ECE1, EGF, EGFR, GAA, TNF
Membrane 11 ACHE, BCL2, CAT, CDK1, ECE1, EGF, EGFR, G6PD, GAA, MT-CYB, NQO1
apical plasma membrane 1 EGFR
basolateral plasma membrane 1 EGFR
extracellular exosome 8 ALB, CAT, CDK1, CRYZ, ECE1, EGF, G6PD, GAA
Lysosome membrane 1 GAA
endoplasmic reticulum 2 ALB, BCL2
extracellular space 7 ACHE, ALB, BCHE, EGF, EGFR, TNF, XDH
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 3 ACHE, ECE1, EGFR
mitochondrion 5 BCL2, CAT, CDK1, CRYZ, MT-CYB
protein-containing complex 5 AHR, ALB, BCL2, CAT, EGFR
intracellular membrane-bounded organelle 3 CAT, G6PD, GAA
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 EGFR
Secreted 4 ACHE, ALB, BCHE, GAA
extracellular region 7 ACHE, ALB, BCHE, CAT, EGF, GAA, TNF
cytoplasmic side of plasma membrane 1 G6PD
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 2 CAT, CDK1
Extracellular side 1 ACHE
anchoring junction 1 ALB
transcription regulator complex 1 AHR
centriolar satellite 1 G6PD
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 CDK1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, EGFR
external side of plasma membrane 2 ECE1, TNF
beta-catenin destruction complex 1 AXIN2
midbody 1 CDK1
Early endosome 1 ECE1
recycling endosome 1 TNF
Single-pass type II membrane protein 2 ECE1, TNF
vesicle 1 ECE1
Mitochondrion inner membrane 1 MT-CYB
Membrane raft 2 EGFR, TNF
pore complex 1 BCL2
focal adhesion 2 CAT, EGFR
Peroxisome 2 CAT, XDH
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
receptor complex 1 EGFR
ciliary basal body 1 ALB
chromatin 1 AHR
phagocytic cup 1 TNF
mitotic spindle 1 CDK1
centriole 1 ALB
spindle pole 1 ALB
chromosome, telomeric region 1 CDK1
blood microparticle 2 ALB, BCHE
Lipid-anchor, GPI-anchor 1 ACHE
aryl hydrocarbon receptor complex 1 AHR
tertiary granule membrane 1 GAA
side of membrane 1 ACHE
myelin sheath 1 BCL2
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, BCHE
platelet alpha granule lumen 2 ALB, EGF
azurophil granule membrane 1 GAA
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 2 EGF, EGFR
respiratory chain complex III 1 MT-CYB
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
spindle microtubule 1 CDK1
death-inducing signaling complex 1 CASP3
cytosolic ribosome 1 RNF25
cyclin-dependent protein kinase holoenzyme complex 1 CDK1
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
Weibel-Palade body 1 ECE1
cyclin A1-CDK1 complex 1 CDK1
cyclin A2-CDK1 complex 1 CDK1
cyclin B1-CDK1 complex 1 CDK1
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
[Isoform H]: Cell membrane 1 ACHE
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Shilin Wen, Jingang Huang, Weishuai Li, Mengke Wu, Felix Steyskal, Jianfang Meng, Xiaobin Xu, Pingzhi Hou, Junhong Tang. Henna plant biomass enhanced azo dye removal: Operating performance, microbial community and machine learning modeling. Chemosphere. 2024 Mar; 352(?):141471. doi: 10.1016/j.chemosphere.2024.141471. [PMID: 38373445]
  • Jin-Hyung Lee, Yong-Guy Kim, Jintae Lee. Antibiofilm activity of lawsone against polymicrobial enterohemorrhagic Escherichia coli O157:H7 and Candida albicans by suppression of curli production and hyphal growth. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Feb; 124(?):155306. doi: 10.1016/j.phymed.2023.155306. [PMID: 38176270]
  • Bolesław Szadkowski, Anna Marzec, Małgorzata Kuśmierek, Małgorzata Piotrowska, Dariusz Moszyński. Functionalization of bamboo fibers with lawsone dye (Lawsonia inermis) to produce bioinspired hybrid color composite with antibacterial activity. International journal of biological macromolecules. 2024 Jan; 259(Pt 1):129178. doi: 10.1016/j.ijbiomac.2023.129178. [PMID: 38184044]
  • K E Zannat, S M Tanzim, A Afrin, N Akter, M S Mostaqim, J B Joynal, M Ferdausee, B C Saha, N H Nira. Antibacterial Effects of Methanol Henna (Lawsone inermis) Leaf Extracts against Two Food Borne Infection Causing Pathogens: Gram-Positive Staphylococcus aureus and Gram Negative Klebsiella pneumoniae. Mymensingh medical journal : MMJ. 2023 Oct; 32(4):1009-1014. doi: . [PMID: 37777894]
  • Mohsen Rezaeian, Maryam Mohamadi, Hassan Ahmadinia, Hamidreza Mohammadi, Ali Ghaffarian-Bahraman. Lead and arsenic contamination in henna samples marketed in Iran. Environmental monitoring and assessment. 2023 Jul; 195(8):913. doi: 10.1007/s10661-023-11532-y. [PMID: 37395865]
  • Beatrycze Nowicka, Jan Walczak, Maja Kapsiak, Karolina Barnaś, Julia Dziuba, Aleksandra Suchoń. Impact of cytotoxic plant naphthoquinones, juglone, plumbagin, lawsone and 2-methoxy-1,4-naphthoquinone, on Chlamydomonas reinhardtii reveals the biochemical mechanism of juglone toxicity by rapid depletion of plastoquinol. Plant physiology and biochemistry : PPB. 2023 Apr; 197(?):107660. doi: 10.1016/j.plaphy.2023.107660. [PMID: 36996637]
  • Hany Tobia Michael, Dhanya Mohan, Hind Aljaghber, Fakhriya Alalawi, Mohammed Railey, Amna Alhadari. Topical Henna Application Causing Acute Kidney Injury and Acute Hemolytic Anemia. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. 2023 Mar; 34(2):178-186. doi: 10.4103/1319-2442.391897. [PMID: 38146728]
  • Mehdi Pasalar, Bahareh Ahadi, Hamid Reza Mirzaei, Judith Buentzel, Mojgan Mehri Ardestani, Shaghayegh Kamian, Ghazaleh Heydarirad. Comparing Dermolina-Henna Cream with Mometasone Cream in Improving Radiodermatitis Among Patients with Breast Cancer: A Randomized Active-Control Double-Blind Clinical Trial. Journal of integrative and complementary medicine. 2022 Nov; 28(11):895-903. doi: 10.1089/jicm.2022.0551. [PMID: 36103288]
  • Antony Stalin, Paul Dhivya, Ding Lin, Yue Feng, Antony Cruz Asharaja, Munusamy Rajiv Gandhi, Balakrishnan Senthamarai Kannan, Subramani Kandhasamy, Appadurai Daniel Reegan, Yuan Chen. Synthesis, Molecular Docking and Mosquitocidal Efficacy of Lawsone and its Derivatives Against the Dengue Vector Aedes aegypti L. (Diptera: Culicidae). Medicinal chemistry (Shariqah (United Arab Emirates)). 2022; 18(2):170-180. doi: 10.2174/1573406417666210727121654. [PMID: 34315380]
  • Esra Yildizhan, Hatice Aslan Sirakaya, Serdal Korkmaz. Therapeutic plasma exchange in non-immune hemolytic anemia associated with henna ingestion: A case report. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2021 Dec; 60(6):103204. doi: 10.1016/j.transci.2021.103204. [PMID: 34275735]
  • Forough Rasouliyan, Masoud Eskandani, Mehdi Jaymand, Sattar Akbari Nakhjavani, Raheleh Farahzadi, Somayeh Vandghanooni, Morteza Eskandani. Preparation, physicochemical characterization, and anti-proliferative properties of Lawsone-loaded solid lipid nanoparticles. Chemistry and physics of lipids. 2021 09; 239(?):105123. doi: 10.1016/j.chemphyslip.2021.105123. [PMID: 34403685]
  • Juliana Figueiredo Peixoto, Adriane da Silva Oliveira, Patrícia Queiroz Monteiro, Luiz Filipe Gonçalves-Oliveira, Valter Viana Andrade-Neto, Vitor Francisco Ferreira, Franklin Souza-Silva, Carlos Roberto Alves. In Silico Insights into the Mechanism of Action of Epoxy-α-Lapachone and Epoxymethyl-Lawsone in Leishmania spp. Molecules (Basel, Switzerland). 2021 Jun; 26(12):. doi: 10.3390/molecules26123537. [PMID: 34200517]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Porkodi Jeyaraman, Michael Samuel, Antonysamy Johnson, Natarajan Raman. Synthesis, characterization, ADMET, in vitro and in vivo studies of mixed ligand metal complexes from a curcumin Schiff base and lawsone. Nucleosides, nucleotides & nucleic acids. 2021; 40(3):242-263. doi: 10.1080/15257770.2020.1867865. [PMID: 33380278]
  • Amin Pasandi Pour, Hassan Farahbakhsh. Lawsonia inermis L. leaves aqueous extract as a natural antioxidant and antibacterial product. Natural product research. 2020 Dec; 34(23):3399-3403. doi: 10.1080/14786419.2019.1569006. [PMID: 30721090]
  • Lian Chee Foong, Jian Yi Chai, Anthony Siong Hock Ho, Brandon Pei Hui Yeo, Yang Mooi Lim, Sheh May Tam. Comparative transcriptome analysis to identify candidate genes involved in 2-methoxy-1,4-naphthoquinone (MNQ) biosynthesis in Impatiens balsamina L. Scientific reports. 2020 09; 10(1):16123. doi: 10.1038/s41598-020-72997-2. [PMID: 32999341]
  • Sharmeen Ishteyaque, Anjali Mishra, Sangeeta Mohapatra, Aparna Singh, Rabi S Bhatta, Narender Tadigoppula, Madhav Nilakanth Mugale. In Vitro: Cytotoxicity, Apoptosis and Ameliorative Potential of Lawsonia inermis Extract in Human Lung, Colon and Liver Cancer Cell Line. Cancer investigation. 2020 Sep; 38(8-9):476-485. doi: 10.1080/07357907.2020.1811300. [PMID: 32845783]
  • Mohammadreza Ebrahimi, Abbas Parham. Using Herbal dyes as an alternative staining method for sperm evaluation. Veterinary medicine and science. 2020 08; 6(3):441-446. doi: 10.1002/vms3.268. [PMID: 32323476]
  • V Villalobos, M J Rial, C Pastor-Vargas, I Esteban, J Cuesta, J Sastre. Occupational Asthma and Rhinitis due to Yellow and Red Henna in a Hairdresser. Journal of investigational allergology & clinical immunology. 2020 Apr; 30(2):133-134. doi: 10.18176/jiaci.0453. [PMID: 31530513]
  • Mariana Rodrigues Xavier, Manuella Maria Silva Santos, Maise Gomes Queiroz, Mariza S de Lima Silva, Alexandre José S Goes, Marcos Antonio De Morais. Lawsone, a 2-hydroxy-1,4-naphthoquinone from Lawsonia inermis (henna), produces mitochondrial dysfunctions and triggers mitophagy in Saccharomyces cerevisiae. Molecular biology reports. 2020 Feb; 47(2):1173-1185. doi: 10.1007/s11033-019-05218-3. [PMID: 31811499]
  • Laura Lozza, Pedro Moura-Alves, Teresa Domaszewska, Carolina Lage Crespo, Ioana Streata, Annika Kreuchwig, Andreas Puyskens, Marina Bechtle, Marion Klemm, Ulrike Zedler, Bogdan Silviu Ungureanu, Ute Guhlich-Bornhof, Anne-Britta Koehler, Manuela Stäber, Hans-Joachim Mollenkopf, Robert Hurwitz, Jens Furkert, Gerd Krause, January Weiner, António Jacinto, Ioana Mihai, Maria Leite-de-Moraes, Frank Siebenhaar, Marcus Maurer, Stefan H E Kaufmann. The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis. Scientific reports. 2019 07; 9(1):10878. doi: 10.1038/s41598-019-47350-x. [PMID: 31350436]
  • Daiva Majiene, Jolita Kuseliauskyte, Arturas Stimbirys, Aiste Jekabsone. Comparison of the Effect of Native 1,4-Naphthoquinones Plumbagin, Menadione, and Lawsone on Viability, Redox Status, and Mitochondrial Functions of C6 Glioblastoma Cells. Nutrients. 2019 Jun; 11(6):. doi: 10.3390/nu11061294. [PMID: 31181639]
  • Małgorzata Rudnicka, Michał Ludynia, Waldemar Karcz. Effects of Naphthazarin (DHNQ) Combined with Lawsone (NQ-2-OH) or 1,4-Naphthoquinone (NQ) on the Auxin-Induced Growth of Zea mays L. Coleoptile Segments. International journal of molecular sciences. 2019 Apr; 20(7):. doi: 10.3390/ijms20071788. [PMID: 30978914]
  • Yoshimi Oda, Souichi Nakashima, Erina Kondo, Seikou Nakamura, Mamiko Yano, Chisa Kubota, Yusuke Masumoto, Minami Hirao, Yuki Ogawa, Hisashi Matsuda. Comparison of lawsone contents among Lawsonia inermis plant parts and neurite outgrowth accelerators from branches. Journal of natural medicines. 2018 Sep; 72(4):890-896. doi: 10.1007/s11418-018-1221-y. [PMID: 29777444]
  • Mahmood Barani, Mohammad Mirzaei, Masoud Torkzadeh-Mahani, Mohammad Hadi Nematollahi. Lawsone-loaded Niosome and its antitumor activity in MCF-7 breast Cancer cell line: a Nano-herbal treatment for Cancer. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 2018 Sep; 26(1):11-17. doi: 10.1007/s40199-018-0207-3. [PMID: 30159762]
  • S Sylvester Darvin, S Esakkimuthu, Erenius Toppo, K Balakrishna, M Gabriel Paulraj, P Pandikumar, S Ignacimuthu, N A Al-Dhabi. Hepatoprotective effect of lawsone on rifampicin-isoniazid induced hepatotoxicity in in vitro and in vivo models. Environmental toxicology and pharmacology. 2018 Jul; 61(?):87-94. doi: 10.1016/j.etap.2018.05.006. [PMID: 29859372]
  • Alexandra G Durán, Nuria Chinchilla, José Mg Molinillo, Francisco A Macías. Influence of lipophilicity in O-acyl and O-alkyl derivatives of juglone and lawsone: a structure-activity relationship study in the search for natural herbicide models. Pest management science. 2018 Mar; 74(3):682-694. doi: 10.1002/ps.4764. [PMID: 29024464]
  • Sameh S M Soliman, Abrar I Alsaadi, Eman G Youssef, Gregory Khitrov, Ayman M Noreddin, Mohamed I Husseiny, Ashraf S Ibrahim. Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. Molecules (Basel, Switzerland). 2017 Dec; 22(12):. doi: 10.3390/molecules22122223. [PMID: 29261103]
  • S H S Dananjaya, R M C Udayangani, Sang Yeop Shin, M Edussuriya, Chamilani Nikapitiya, Jehee Lee, Mahanama De Zoysa. In vitro and in vivo antifungal efficacy of plant based lawsone against Fusarium oxysporum species complex. Microbiological research. 2017 Aug; 201(?):21-29. doi: 10.1016/j.micres.2017.04.011. [PMID: 28602398]
  • Lamis Beshir, Babiker Kaballo, Donald Young. Attempted suicide by ingestion of hair dye containing p-phenylenediamine: a case report. Annals of clinical biochemistry. 2017 Jul; 54(4):507-510. doi: 10.1177/0004563216685117. [PMID: 27923888]
  • Hatnagar Sarang, Pijakala Rajani, Madhugiri Mallaiah Vasanthakumari, Patel Mohana Kumara, Ramamoorthy Siva, Gudasalamani Ravikanth, R Uma Shaanker. An endophytic fungus, Gibberella moniliformis from Lawsonia inermis L. produces lawsone, an orange-red pigment. Antonie van Leeuwenhoek. 2017 Jul; 110(7):853-862. doi: 10.1007/s10482-017-0858-y. [PMID: 28315019]
  • Shi-Bin Wang, Zhenzhou Tao, Ping Li. Lawsone suppresses azoxymethane mediated colon cancer in rats and reduces proliferation of DLD-1 cells via NF-κB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 May; 89(?):152-161. doi: 10.1016/j.biopha.2017.01.169. [PMID: 28222396]
  • Ana Carolina Rennó Sodero, Bárbara Abrahim-Vieira, Pedro Henrique Monteiro Torres, Pedro Geraldo Pascutti, Célia Rs Garcia, Vitor Francisco Ferreira, David Rodrigues da Rocha, Sabrina Baptista Ferreira, Floriano Paes Silva. Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling. Memorias do Instituto Oswaldo Cruz. 2017 Apr; 112(4):299-308. doi: 10.1590/0074-02760160417. [PMID: 28327793]
  • Aysha Aslam, Faisal Samee, Muhammad Zaman, Attique Ur Rahman Mufti, Atiq Ur Rehman. FORMULATION AND ASSESSMENT OF SEMI-SOLID CARRIER INCORPORATED WITH HERBAL EXTRACT OF LAWSONIA INERMIS. Acta poloniae pharmaceutica. 2017 Mar; 74(2):497-504. doi: ". [PMID: 29624255]
  • Ayca Aktas Sukuroglu, Dilek Battal, Sema Burgaz. Monitoring of Lawsone, p-phenylenediamine and heavy metals in commercial temporary black henna tattoos sold in Turkey. Contact dermatitis. 2017 Feb; 76(2):89-95. doi: 10.1111/cod.12702. [PMID: 27757963]
  • Ruchi Badoni Semwal, Deepak Kumar Semwal, Sandra Combrinck, Catherine Cartwright-Jones, Alvaro Viljoen. Lawsonia inermis L. (henna): ethnobotanical, phytochemical and pharmacological aspects. Journal of ethnopharmacology. 2014 Aug; 155(1):80-103. doi: 10.1016/j.jep.2014.05.042. [PMID: 24886774]
  • Farzanehsadat Minoo, Masume Nouri, Simin Dashti-Khavidaki. Possible nephrotoxicity after topical application of a natural herb, henna. Iranian journal of kidney diseases. 2014 Jun; 8(4):349-51. doi: NULL. [PMID: 25001148]
  • Serena Fiorito, Francesco Epifano, Céline Bruyère, Véronique Mathieu, Robert Kiss, Salvatore Genovese. Growth inhibitory activity for cancer cell lines of lapachol and its natural and semi-synthetic derivatives. Bioorganic & medicinal chemistry letters. 2014 Jan; 24(2):454-7. doi: 10.1016/j.bmcl.2013.12.049. [PMID: 24374273]
  • Veronika Vaverkova, Oldrich Vrana, Vojtech Adam, Tomas Pekarek, Josef Jampilek, Petr Babula. The study of naphthoquinones and their complexes with DNA by using Raman spectroscopy and surface enhanced Raman spectroscopy: new insight into interactions of DNA with plant secondary metabolites. BioMed research international. 2014; 2014(?):461393. doi: 10.1155/2014/461393. [PMID: 25045679]
  • Govind J Kapadia, G Subba Rao, Rajagopalan Sridhar, Eiichiro Ichiishi, Midori Takasaki, Nobutaka Suzuki, Takao Konoshima, Akira Iida, Harukuni Tokuda. Chemoprevention of skin cancer: effect of Lawsonia inermis L. (Henna) leaf powder and its pigment artifact, lawsone in the Epstein- Barr virus early antigen activation assay and in two-stage mouse skin carcinogenesis models. Anti-cancer agents in medicinal chemistry. 2013 Dec; 13(10):1500-7. doi: 10.2174/18715206113139990096. [PMID: 23848207]
  • Sandeep Biradar, B Veeresh. Protective effect of lawsone on L-Arginine induced acute pancreatitis in rats. Indian journal of experimental biology. 2013 Mar; 51(3):256-61. doi: . [PMID: 23678547]
  • Nadjib Rahmoun, Zahia Boucherit-Otmani, Kebir Boucherit, Mohammed Benabdallah, Noureddine Choukchou-Braham. Antifungal activity of the Algerian Lawsonia inermis (henna). Pharmaceutical biology. 2013 Jan; 51(1):131-5. doi: 10.3109/13880209.2012.715166. [PMID: 23126251]
  • Thilo Christopher Fischer, Christian Gosch, Beate Mirbeth, Markus Gselmann, Veronika Thallmair, Karl Stich. Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora. Journal of agricultural and food chemistry. 2012 Dec; 60(49):12074-81. doi: 10.1021/jf303584r. [PMID: 23163769]
  • Rohan Pradhan, Prasad Dandawate, Alok Vyas, Subhash Padhye, Bernhard Biersack, Rainer Schobert, Aamir Ahmad, Fazlul H Sarkar. From body art to anticancer activities: perspectives on medicinal properties of henna. Current drug targets. 2012 Dec; 13(14):1777-98. doi: 10.2174/138945012804545588. [PMID: 23140289]
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