1,9-Heptadecadiene-4,6-diyne-3,8-diol, (3S,8S,9Z)- (BioDeep_00000172512)

Main id: BioDeep_00000407529

 

human metabolite blood metabolite


代谢物信息卡片


1,9-Heptadecadiene-4,6-diyne-3,8-diol, (3S,8S,9Z)-

化学式: C17H24O2 (260.17762039999997)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CC(O)C#CC#CC(O)C=CCCCCCCC
InChI: InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3

描述信息

同义名列表

5 个代谢物同义名

1,9-Heptadecadiene-4,6-diyne-3,8-diol, (3S,8S,9Z)-; heptadeca-1,9-diene-4,6-diyne-3,8-diol; Heptadeca-1,9-dien-4,6-diyne-3,8-diol; falcarindiol; falcalindiol



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Likang Zhao, Changkai Li, Meng Zhang, Honglian Li, Shengli Ding, Xi Zhao, Lianjuan Yang, Jia Liu, Qing X Li, Risong Na. Design, Synthesis, and Antifungal Activity of Polyacetylenic Alcohol Derivatives and Stereoisomers against Phytopathogenic Fungi. Journal of agricultural and food chemistry. 2023 Jun; ?(?):. doi: 10.1021/acs.jafc.3c00924. [PMID: 37261403]
  • Siyue Kan, Jingwen Tan, Qing Cai, Lulu An, Zhiqin Gao, Hong Yang, Siyu Liu, Risong Na, Lianjuan Yang. Synergistic activity of the combination of falcarindiol and itraconazole in vitro against dermatophytes. Frontiers in cellular and infection microbiology. 2023; 13(?):1128000. doi: 10.3389/fcimb.2023.1128000. [PMID: 37207188]
  • Gokay Albayrak, Serdar Demir, Halil Koyu, Sura Baykan. Anticholinesterase Compounds from Endemic Prangos uechtritzii. Chemistry & biodiversity. 2022 Nov; 19(11):e202200557. doi: 10.1002/cbdv.202200557. [PMID: 36201258]
  • Kyung-Ran Park, Hyun Hee Leem, Yoon-Ju Kwon, Il Keun Kwon, Jin Tae Hong, Hyung-Mun Yun. Falcarindiol Stimulates Apoptotic and Autophagic Cell Death to Attenuate Cell Proliferation, Cell Division, and Metastasis through the PI3K/AKT/mTOR/p70S6K Pathway in Human Oral Squamous Cell Carcinomas. The American journal of Chinese medicine. 2022; 50(1):295-311. doi: 10.1142/s0192415x22500112. [PMID: 34931585]
  • Chaoyue Zhao, Hongda Zheng, Liman Zhou, Hongrui Ji, Lu Zhao, Wengong Yu, Qianhong Gong. Falcarindiol Isolated from Notopterygium incisum Inhibits the Quorum Sensing of Pseudomonas aeruginosa. Molecules (Basel, Switzerland). 2021 Sep; 26(19):. doi: 10.3390/molecules26195896. [PMID: 34641440]
  • Chong-Zhi Wang, Yun Luo, Wei-Hua Huang, Jinxiang Zeng, Chun-Feng Zhang, Mallory Lager, Wei Du, Ming Xu, Chun-Su Yuan. Falcarindiol and dichloromethane fraction are bioactive components in Oplopanax elatus: Colorectal cancer chemoprevention via induction of apoptosis and G2/M cell cycle arrest mediated by cyclin A upregulation. Journal of applied biomedicine. 2021; 19(2):113-124. doi: 10.32725/jab.2021.013. [PMID: 34754259]
  • Ju Eun Jeon, Jung-Gun Kim, Curt R Fischer, Niraj Mehta, Cosima Dufour-Schroif, Kimberly Wemmer, Mary Beth Mudgett, Elizabeth Sattely. A Pathogen-Responsive Gene Cluster for Highly Modified Fatty Acids in Tomato. Cell. 2020 01; 180(1):176-187.e19. doi: 10.1016/j.cell.2019.11.037. [PMID: 31923394]
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  • Emma Pipó-Ollé, Prasad Walke, Martine K Notabi, Rime B El-Houri, Morten Østergaard Andersen, David Needham, Eva C Arnspang. Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells. Journal of visualized experiments : JoVE. 2019 02; ?(144):. doi: 10.3791/59094. [PMID: 30799864]
  • Lucas Busta, Won Cheol Yim, Evan William LaBrant, Peng Wang, Lindsey Grimes, Kiah Malyszka, John C Cushman, Patricia Santos, Dylan K Kosma, Edgar B Cahoon. Identification of Genes Encoding Enzymes Catalyzing the Early Steps of Carrot Polyacetylene Biosynthesis. Plant physiology. 2018 12; 178(4):1507-1521. doi: 10.1104/pp.18.01195. [PMID: 30333150]
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  • Gai Liu, Daowan Lai, Qi Zhi Liu, Ligang Zhou, Zhi Long Liu. Identification of Nematicidal Constituents of Notopterygium incisum Rhizomes against Bursaphelenchus xylophilus and Meloidogyne incognita. Molecules (Basel, Switzerland). 2016 Sep; 21(10):. doi: 10.3390/molecules21101276. [PMID: 27669203]
  • Wei Sun, Yi-Sheng He, Ling-Hui Xu, Bi-Ying Zhang, Lian-Wen Qi, Jie Yang, Ping Li, Xiao-Dong Wen. Pharmacokinetic profiles of falcarindiol and oplopandiol in rats after oral administration of polyynes extract of Oplopanax elatus. Chinese journal of natural medicines. 2016 Sep; 14(9):714-720. doi: 10.1016/s1875-5364(16)30085-1. [PMID: 27667518]
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  • Jun Yoshida, Hiroko Seino, Yoshiaki Ito, Toshimitsu Nakano, Takumi Satoh, Yoshiko Ogane, Saori Suwa, Hiroyuki Koshino, Ken-Ichi Kimura. Inhibition of glycogen synthase kinase-3β by falcarindiol isolated from Japanese Parsley (Oenanthe javanica). Journal of agricultural and food chemistry. 2013 Aug; 61(31):7515-21. doi: 10.1021/jf401042m. [PMID: 23895038]
  • Juan David Guzman, Dimitrios Evangelopoulos, Antima Gupta, Jose M Prieto, Simon Gibbons, Sanjib Bhakta. Antimycobacterials from lovage root (Ligusticum officinale Koch). Phytotherapy research : PTR. 2013 Jul; 27(7):993-8. doi: 10.1002/ptr.4823. [PMID: 22899555]
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  • Atanas G Atanasov, Martina Blunder, Nanang Fakhrudin, Xin Liu, Stefan M Noha, Clemens Malainer, Matthias P Kramer, Amina Cocic, Olaf Kunert, Andreas Schinkovitz, Elke H Heiss, Daniela Schuster, Verena M Dirsch, Rudolf Bauer. Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gamma. PloS one. 2013; 8(4):e61755. doi: 10.1371/journal.pone.0061755. [PMID: 23630612]
  • Rana G Zaini, Kirsten Brandt, Malcolm R Clench, Christine L Le Maitre. Effects of bioactive compounds from carrots (Daucus carota L.), polyacetylenes, beta-carotene and lutein on human lymphoid leukaemia cells. Anti-cancer agents in medicinal chemistry. 2012 Jul; 12(6):640-52. doi: 10.2174/187152012800617704. [PMID: 22263789]
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  • Jin Woo Lee, Cheong-Yong Yun, Eunmiri Roh, Chul Lee, Qinghao Jin, Kwon Ki Bang, Sang-Hun Jung, Dongho Lee, Mi Kyeong Lee, Youngsoo Kim, Bang Yeon Hwang. Melanogenesis inhibitory bisabolane-type sesquiterpenoids from the roots of Angelica koreana. Bioorganic & medicinal chemistry letters. 2012 Apr; 22(8):2927-31. doi: 10.1016/j.bmcl.2012.02.047. [PMID: 22450129]
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  • Sébastien Louarn, Arkadiusz Nawrocki, Merete Edelenbos, Dan F Jensen, Ole N Jensen, David B Collinge, Birgit Jensen. The influence of the fungal pathogen Mycocentrospora acerina on the proteome and polyacetylenes and 6-methoxymellein in organic and conventionally cultivated carrots (Daucus carota) during post harvest storage. Journal of proteomics. 2012 Jan; 75(3):962-77. doi: 10.1016/j.jprot.2011.10.014. [PMID: 22075166]
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  • Tomokazu Ohnuma, Eisaburo Anan, Rika Hoashi, Yuika Takeda, Takahito Nishiyama, Kenichiro Ogura, Akira Hiratsuka. Dietary diacetylene falcarindiol induces phase 2 drug-metabolizing enzymes and blocks carbon tetrachloride-induced hepatotoxicity in mice through suppression of lipid peroxidation. Biological & pharmaceutical bulletin. 2011; 34(3):371-8. doi: 10.1248/bpb.34.371. [PMID: 21372387]
  • Lars Kjellenberg, Eva Johansson, Karl-Erik Gustavsson, Marie E Olsson. Effects of harvesting date and storage on the amounts of polyacetylenes in carrots, Daucus carota. Journal of agricultural and food chemistry. 2010 Nov; 58(22):11703-8. doi: 10.1021/jf103182c. [PMID: 20964297]
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